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Volumn 88, Issue 5, 2017, Pages 426-432

Blood-brain barrier leakage is more widespread in patients with cerebral small vessel disease

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AGED; AGING; ARTICLE; ARTIFACT; BLOOD BRAIN BARRIER; BLOOD BRAIN BARRIER LEAKAGE; BRAIN CORTEX; BRAIN DISEASE; BRAIN SIZE; CARDIOVASCULAR RISK; CEREBROVASCULAR DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE ASSOCIATION; DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING; FEMALE; GRAY MATTER; HISTOGRAM; HUMAN; HYPERCHOLESTEROLEMIA; LACUNAR STROKE; MAJOR CLINICAL STUDY; MALE; PLASMA VOLUME; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING; WHITE MATTER; CAPILLARY PERMEABILITY; CARDIOVASCULAR DISEASE; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC IMAGING; METABOLISM; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX; SEXUAL DEVELOPMENT; STATISTICAL MODEL;

EID: 85011263099     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000003556     Document Type: Article
Times cited : (159)

References (31)
  • 1
    • 84876488222 scopus 로고    scopus 로고
    • Mechanisms of sporadic cerebral small vessel disease: Insights from neuroimaging
    • Wardlaw JM, Smith C, Dichgans M. Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging. Lancet Neurol 2013;12:483-497.
    • (2013) Lancet Neurol , vol.12 , pp. 483-497
    • Wardlaw, J.M.1    Smith, C.2    Dichgans, M.3
  • 2
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010;9:689-701.
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 3
    • 0141596878 scopus 로고    scopus 로고
    • Pathophysiology of cerebral small vessels in vascular cognitive impairment
    • Pantoni L, Simoni M. Pathophysiology of cerebral small vessels in vascular cognitive impairment. Int Psychogeriatr 2003;15(suppl 1):59-65.
    • (2003) Int Psychogeriatr , vol.15 , pp. 59-65
    • Pantoni, L.1    Simoni, M.2
  • 4
    • 0031922362 scopus 로고    scopus 로고
    • A population study on blood-brain barrier function in 85-year-olds: Relation to Alzheimer's disease and vascular dementia
    • Skoog I, Wallin A, Fredman P, et al. A population study on blood-brain barrier function in 85-year-olds: Relation to Alzheimer's disease and vascular dementia. Neurology 1998;50:966-971.
    • (1998) Neurology , vol.50 , pp. 966-971
    • Skoog, I.1    Wallin, A.2    Fredman, P.3
  • 5
    • 0027402238 scopus 로고
    • Cerebrospinal fluid proteins in patients with leucoaraiosis: Possible abnormalities in blood-brain barrier function
    • Pantoni L, Inzitari D, Pracucci G, et al. Cerebrospinal fluid proteins in patients with leucoaraiosis: possible abnormalities in blood-brain barrier function. J Neurol Sci 1993;115:125-131.
    • (1993) J Neurol, Sci , vol.115 , pp. 125-131
    • Pantoni, L.1    Inzitari, D.2    Pracucci, G.3
  • 6
    • 0037338557 scopus 로고    scopus 로고
    • Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?
    • Wardlaw JM, Sandercock PA, Dennis MS, Starr J. Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke 2003;34: 806-812.
    • (2003) Stroke , vol.34 , pp. 806-812
    • Wardlaw, J.M.1    Sandercock, P.A.2    Dennis, M.S.3    Starr, J.4
  • 7
    • 67349220310 scopus 로고    scopus 로고
    • Blood-brain barrier alterations in ageing and dementia
    • Popescu BO, Toescu EC, Popescu LM, et al. Blood-brain barrier alterations in ageing and dementia. J Neurol Sci 2009;283:99-106.
    • (2009) J Neurol Sci , vol.283 , pp. 99-106
    • Popescu, B.O.1    Toescu, E.C.2    Popescu, L.M.3
  • 8
    • 62549145764 scopus 로고    scopus 로고
    • Lacunar stroke is associated with diffuse blood-brain barrier dysfunction
    • Wardlaw JM, Doubal F, Armitage P, et al. Lacunar stroke is associated with diffuse blood-brain barrier dysfunction. Ann Neurol 2009;65:194-202.
    • (2009) Ann Neurol , vol.65 , pp. 194-202
    • Wardlaw, J.M.1    Doubal, F.2    Armitage, P.3
  • 9
    • 76549093011 scopus 로고    scopus 로고
    • Bloodbrain barrier permeability is increased in normal-Appearing white matter in patients with lacunar stroke and leucoaraiosis
    • Topakian R, Barrick TR, Howe FA, Markus HS. Bloodbrain barrier permeability is increased in normal-Appearing white matter in patients with lacunar stroke and leucoaraiosis. J Neurol Neurosurg Psychiatry 2010;81:192-197.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 192-197
    • Topakian, R.1    Barrick, T.R.2    Howe, F.A.3    Markus, H.S.4
  • 10
    • 79961208538 scopus 로고    scopus 로고
    • Blood-brain barrier permeability abnormalities in vascular cognitive impairment
    • Taheri S, Gasparovic C, Huisa BN, et al. Blood-brain barrier permeability abnormalities in vascular cognitive impairment. Stroke 2011;42:2158-2163.
    • (2011) Stroke , vol.42 , pp. 2158-2163
    • Taheri, S.1    Gasparovic, C.2    Huisa, B.N.3
  • 11
    • 77951842306 scopus 로고    scopus 로고
    • Metabolic syndrome relates to lacunar stroke without white matter lesions: A study in first-ever lacunar stroke patients
    • Zhang CE, van Raak EP, Rouhl RP, et al. Metabolic syndrome relates to lacunar stroke without white matter lesions: A study in first-ever lacunar stroke patients. Cerebrovasc Dis 2010;29:503-507.
    • (2010) Cerebrovasc Dis , vol.29 , pp. 503-507
    • Zhang, C.E.1    Van Raak, E.P.2    Rouhl, R.P.3
  • 12
    • 84880391350 scopus 로고    scopus 로고
    • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
    • Wardlaw JM, Smith EE, Biessels GJ, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013;12:822-838.
    • (2013) Lancet Neurol , vol.12 , pp. 822-838
    • Wardlaw, J.M.1    Smith, E.E.2    Biessels, G.J.3
  • 13
    • 0026680886 scopus 로고
    • Symptomatic carotid artery stenosis: A solvable problem: North American Symptomatic Carotid Endarterectomy Trial
    • Barnett HJ, Barnes RW, Clagett GP, Ferguson GG, Robertson JT, Walker PM. Symptomatic carotid artery stenosis: A solvable problem: North American Symptomatic Carotid Endarterectomy Trial. Stroke 1992;23:1048-1053.
    • (1992) Stroke , vol.23 , pp. 1048-1053
    • Barnett, H.J.1    Barnes, R.W.2    Clagett, G.P.3    Ferguson, G.G.4    Robertson, J.T.5    Walker, P.M.6
  • 14
    • 80055019036 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in acute and chronic cerebrovascular disease
    • Yang Y, Rosenberg GA. Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke 2011;42: 3323-3328.
    • (2011) Stroke , vol.42 , pp. 3323-3328
    • Yang, Y.1    Rosenberg, G.A.2
  • 15
    • 80052400687 scopus 로고    scopus 로고
    • Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American Stroke Association
    • Gorelick PB, Scuteri A, Black SE, et al. Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42:2672-2713.
    • (2011) Stroke , vol.42 , pp. 2672-2713
    • Gorelick, P.B.1    Scuteri, A.2    Black, S.E.3
  • 17
    • 84992111543 scopus 로고    scopus 로고
    • Blood-brain barrier leakage in patients with early Alzheimer disease
    • van de Haar HJ, Burgmans S, Jansen JF, et al. Blood-brain barrier leakage in patients with early Alzheimer disease. Radiology 2016;281:527-535.
    • (2016) Radiology , vol.281 , pp. 527-535
    • Van De Haar, H.J.1    Burgmans, S.2    Jansen, J.F.3
  • 18
    • 70449411152 scopus 로고    scopus 로고
    • Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T (1)-weighted MRI at 3 tesla
    • Larsson HB, Courivaud F, Rostrup E, Hansen AE. Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T (1)-weighted MRI at 3 tesla. Magn Reson Med 2009;62: 1270-1281.
    • (2009) Magn Reson Med , vol.62 , pp. 1270-1281
    • Larsson, H.B.1    Courivaud, F.2    Rostrup, E.3    Hansen, A.E.4
  • 19
    • 84862997809 scopus 로고    scopus 로고
    • Freesurfer
    • Fischl B. FreeSurfer. Neuroimage 2012;62:774-781.
    • (2012) Neuroimage , vol.62 , pp. 774-781
    • Fischl, B.1
  • 20
    • 62049085638 scopus 로고    scopus 로고
    • White matter lesion extension to automatic brain tissue segmentation on MRI
    • de Boer R, Vrooman HA, van der Lijn F, et al. White matter lesion extension to automatic brain tissue segmentation on MRI. Neuroimage 2009;45:1151-1161.
    • (2009) Neuroimage , vol.45 , pp. 1151-1161
    • De Boer, R.1    Vrooman, H.A.2    Van Der Lijn, F.3
  • 21
    • 0036425968 scopus 로고    scopus 로고
    • Improved optimization for the robust and accurate linear registration and motion correction of brain images
    • Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 2002; 17:825-841.
    • (2002) Neuroimage , vol.17 , pp. 825-841
    • Jenkinson, M.1    Bannister, P.2    Brady, M.3    Smith, S.4
  • 22
    • 78449255742 scopus 로고    scopus 로고
    • Reproducibility of the gadolinium concentration measurements and of the fitting parameters of the vascular input function in the superior sagittal sinus in a patient population
    • Lavini C, Verhoeff JJ. Reproducibility of the gadolinium concentration measurements and of the fitting parameters of the vascular input function in the superior sagittal sinus in a patient population. Magn Reson Imaging 2010;28:1420-1430.
    • (2010) Magn Reson Imaging , vol.28 , pp. 1420-1430
    • Lavini, C.1    Verhoeff, J.J.2
  • 23
    • 0022389649 scopus 로고
    • Graphical evaluation of blood-Tobrain transfer constants from multiple-Time uptake data: Generalizations
    • Patlak CS, Blasberg RG. Graphical evaluation of blood-Tobrain transfer constants from multiple-Time uptake data: generalizations. J Cereb Blood Flow Metab 1985;5:584-590.
    • (1985) J Cereb Blood Flow Metab , vol.5 , pp. 584-590
    • Patlak, C.S.1    Blasberg, R.G.2
  • 24
  • 25
    • 53049101053 scopus 로고    scopus 로고
    • Neuropathologic correlates of white matter hyperintensities
    • Young VG, Halliday GM, Kril JJ. Neuropathologic correlates of white matter hyperintensities. Neurology 2008;71: 804-811.
    • (2008) Neurology , vol.71 , pp. 804-811
    • Young, V.G.1    Halliday, G.M.2    Kril, J.J.3
  • 26
    • 84916224368 scopus 로고    scopus 로고
    • Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people
    • Bridges LR, Andoh J, Lawrence AJ, et al. Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. J Neuropathol Exp Neurol 2014;73:1026-1033.
    • (2014) J Neuropathol Exp Neurol , vol.73 , pp. 1026-1033
    • Bridges, L.R.1    Andoh, J.2    Lawrence, A.J.3
  • 27
    • 84921326695 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in the aging human hippocampus
    • Montagne A, Barnes SR, Sweeney MD, et al. Blood-brain barrier breakdown in the aging human hippocampus. Neuron 2015;85:296-302.
    • (2015) Neuron , vol.85 , pp. 296-302
    • Montagne, A.1    Barnes, S.R.2    Sweeney, M.D.3
  • 30
    • 84883333125 scopus 로고    scopus 로고
    • Incident lacunes preferentially localize to the edge of white matter hyperintensities: Insights into the pathophysiology of cerebral small vessel disease
    • Duering M, Csanadi E, Gesierich B, et al. Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel disease. Brain 2013;136:2717-2726.
    • (2013) Brain , vol.136 , pp. 2717-2726
    • Duering, M.1    Csanadi, E.2    Gesierich, B.3
  • 31
    • 84930897116 scopus 로고    scopus 로고
    • Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood-brain barrier permeability using dynamic contrast-enhanced MRI
    • Barnes SR, Ng TS, Montagne A, Law M, Zlokovic BV, Jacobs RE. Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood-brain barrier permeability using dynamic contrast-enhanced MRI. Magn Reson Med 2016;75:1967-1977.
    • (2016) Magn Reson Med , vol.75 , pp. 1967-1977
    • Barnes, S.R.1    Ng, T.S.2    Montagne, A.3    Law, M.4    Zlokovic, B.V.5    Jacobs, R.E.6


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