Metabolic syndrome relates to lacunar stroke without white matter lesions: A study in first-ever lacunar stroke patients

Cerebrovascular Diseases

Volumn 29, Issue 5, 2010, Pages 503-507

  Zhang, C E ^a   Van Raak, E P M ^a   Rouhl, R P W ^a   Lodder, J ^a,b   Staals, J ^a   Knottnerus, I L H ^a   Van Oostenbrugge, R J ^a,b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Lacunar infarction; Lacunar stroke; Metabolic syndrome; White matter lesions

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN DAMAGE; BRAIN HEMORRHAGE; BRAIN INFARCTION; CONTROLLED STUDY; FEMALE; HUMAN; LACUNAR STROKE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STROKE; WHITE MATTER;

AGED; AGED, 80 AND OVER; BRAIN; BRAIN INFARCTION; CASE-CONTROL STUDIES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; STROKE;

EID: 77951842306     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000297967     Document Type: Article

References (26)

1. Cornier MA, Dabelea D, Hernandez TL, Lindstrom RC, Steig AJ, Stob NR, Van Pelt RE, Wang H Eckel RH: The metabolic syndrome. Endocr Rev 2008; 29: 777-822.
2. Day C: Metabolic syndrome, or what you will: definitions and epidemiology. Diab Vasc Dis Res 2007; 4: 32-38. (Pubitemid 46649071)
3. Plutzky J: A cardiologist's perspective on cardiometabolic risk. Am J Cardiol 2007; 100: 3P-6P. (Pubitemid 350278499)
4. Butler J, Rodondi N, Zhu Y, et al: Metabolic syndrome and the risk of cardiovascular disease in older adults. J Am Coll Cardiol 2006; 47: 1595-1602.
5. Dekker JM, Girman C, Rhodes T, et al: Metabolic syndrome and 10-year cardiovascular disease risk in the Hoorn Study. Circulation. 2005; 112: 666-673. (Pubitemid 41099045)
6. Gorter PM, Olijhoek JK, van der Graaf Y, Algra A, Rabelink TJ, Visseren FL: Prevalence of the metabolic syndrome in patients with coronary heart disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm. Atherosclerosis 2004; 173: 363-369. (Pubitemid 38469808)
7. Bang OY, Kim JW, Lee JH, Lee MA, Lee PH, Joo IS, Huh K: Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology 205; 65: 296-298. (Pubitemid 41022378)
8. Ovbiagele B, Saver JL, Lynn MJ, Chimowitz M: Impact of metabolic syndrome on prognosis of symptomatic intracranial atherostenosis. Neurology 2006; 66: 1344-1349. (Pubitemid 43739642)
9. Li W, Ma D, Liu M, Liu H, Feng S, Hao Z, Wu B, Zhang S: Association between metabolic syndrome and risk of stroke: a meta-analysis of cohort studies. Cerebrovasc Dis 2008; 25: 539-554. (Pubitemid 351861472)
10. Gil-Nunez A: The metabolic syndrome and cerebrovascular disease: suspicion and evidence. Cerebrovasc Dis 2007; 24(suppl 1):64-75. (Pubitemid 350035854)
11. Fisher CM: The arterial lesions underlying lacunes. Acta Neuropathol (Berl) 1968; 12: 1-15.
12. Lammie GA, Brannan F, Slattery J, Warlow J: Nonhypertensive cerebral small-vessel disease: an autopsy study. Stroke 1997; 28: 2222-2229. (Pubitemid 27497927)
13. Markus HS, Lythgoe DJ, Ostegaard L, O'Sullivan M, Williams SC: Reduced CBF in white matter in ischemic leukoaraiosis demonstrate using quantitative exogenous contrast based perusion MRI. J Neurol Neurosurg Psychiatry 2000; 69: 48-53. (Pubitemid 30410414)
14. Boiten J, Lodder J, Kessels F: Two clinically distinct lacunar infarct entities? A hypothesis. Stroke 1993; 24: 652-656. (Pubitemid 23134281)
15. de Jong G, Kessels F, Lodder J: Two types of lacunar infarcts: further arguments from a study on prognosis. Stroke 2002; 33: 2072-2076. (Pubitemid 34840070)
16. Rouhl RP, van Oostenbrugge RJ, Knottnerus IL, Staals JE, Lodder J: Virchow-Robin spaces relate to cerebral small vessel disease severity. J Neurol 2008; 255: 692-696.
17. Mounier-Vehier F, Leys D, Pruvo JP: Stroke patterns in unilateral atherothrombotic occlusion of the internal carotid artery. Stroke 1995; 26: 422-425.
18. Warlow CP , Dennis MS, Wardlow JM, Bamford JM, Hankey GJ, Sandercock PAG, Rinkel G, Langhorne P, Sudlow C, Rothwell P: What pathological type of stroke is it? In: Stroke: A Practical Guide to Management, ed 2. Oxford, Blackwell Science, 2008, pp 151-222.
19. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497.
20. Takahashi K, Bokura H, Kobayashi S, Iijima K, Nagai A, Yamaguchi S: Metabolic syndrome increases the risk of ischemic stroke in women. Intern Med 2007; 46: 643-648. (Pubitemid 46845833)
21. Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA: MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR AM J Roentgenol 1987; 149: 351-356. (Pubitemid 17104996)
22. Rincon F, Sacco RL, Kranwinkel G, Xu Q, Paik MC, Boden-Albala B, Elkind MSV: Incidence and risk factors of intracranial atherosclerotic stroke: the Northern Manhattan Stroke Study. Cerebrovasc Dis 2009; 28: 65-71.
23. Bang OY, Saver JL, Liebeskind DS, Pineda S, Ovbiagele B: Association of serum lipid indices with large artery atherosclerotic stroke. Neurology 2008; 70: 841-847. (Pubitemid 351367520)
24. Laloux P, Galanti L, Jamart J: Lipids in ischemic stroke subtypes. Acta Neurol Belg 2004; 104: 13-19. (Pubitemid 38559372)
25. Milionis HJ, Rizos E, Goudevenos J, Seferiadis K, Mikhailidis DP, Elisaf MS: Components of the metabolic syndrome and risk for first-ever ischemic nonembolic stroke in elderly subjects. Stroke 2005; 36: 1372-1376. (Pubitemid 40967496)
26. Park K, Yasuda N, Toyonaga S, Tsubosaki E, Nakabayashi H, Shimizu K: Significant associations of metabolic syndrome and its components with silent lacunar infarction in middle aged subjects. J Neurol Neurosurg Psychiatry 2008; 79: 719-721. (Pubitemid 351829449)