Optimal acquisition and modeling parameters for accurate assessment of low Ktrans blood-brain barrier permeability using dynamic contrast-enhanced MRI

Magnetic Resonance in Medicine

Volumn 75, Issue 5, 2016, Pages 1967-1977

  Barnes, Samuel R ^a   Ng, Thomas S C ^a,b   Montagne, Axel ^c   Law, Meng ^c   Zlokovic, Berislav V ^c   Jacobs, Russell E ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

blood brain barrier; DCE MRI; Ktrans estimation; parameter optimization; permeability

Indexed keywords

MAGNETIC RESONANCE IMAGING; MECHANICAL PERMEABILITY; MERGERS AND ACQUISITIONS; NEURODEGENERATIVE DISEASES; POSITRON EMISSION TOMOGRAPHY; TISSUE;

ALZHEIMER'S DISEASE; BLOOD-BRAIN BARRIER; CONTRAST TO NOISE RATIO; DCE-MRI; DYNAMIC CONTRAST ENHANCED MRI; EXTRACELLULAR VOLUMES; PARAMETER OPTIMIZATION; TEMPORAL RESOLUTION;

BLOOD;

GADOBENATE DIMEGLUMINE; CONTRAST MEDIUM;

ACCURACY; ADULT; ARTICLE; BIOLOGICAL MODEL; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTRAST TO NOISE RATIO; CONTROLLED STUDY; DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING; FEMALE; HUMAN; HUMAN TISSUE; IMAGING; KINETICS; MALE; MATHEMATICAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIMIZED IMAGE ACQUISITION; RADIOLOGICAL PARAMETERS; RADIOLOGICAL PROCEDURES; SCAN DURATION; SIGNAL DRIFT; SIMULATION; TEMPORAL RESOLUTION; TISSUE EXTRAVASCULAR EXTRACELLULAR VOLUME FRACTION; AGED; ALGORITHM; ALZHEIMER DISEASE; CHEMISTRY; COMPUTER SIMULATION; DEGENERATIVE DISEASE; DIAGNOSTIC IMAGING; IMAGE PROCESSING; MIDDLE AGED; MULTIPLE SCLEROSIS; NORMAL DISTRIBUTION; PERMEABILITY; PROCEDURES; REPRODUCIBILITY; SIGNAL PROCESSING; YOUNG ADULT;

ADULT; AGED; ALGORITHMS; ALZHEIMER DISEASE; BLOOD-BRAIN BARRIER; COMPUTER SIMULATION; CONTRAST MEDIA; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NEURODEGENERATIVE DISEASES; NORMAL DISTRIBUTION; PERMEABILITY; REPRODUCIBILITY OF RESULTS; SIGNAL PROCESSING, COMPUTER-ASSISTED; YOUNG ADULT;

EID: 84930897116     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25793     Document Type: Article

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