Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 5, 2017, Pages E859-E868

  Eisner, Verónica ^a,b   Cupo, Ryan R ^a   Gao, Erhe ^c   Csordás, György ^a   Slovinsky, William S ^a   Paillard, Melanie ^a   Cheng, Lan ^a   Ibetti, Jessica ^c   Chen, S R Wayne ^d   Chuprun, J Kurt ^c   Hoek, Jan B ^a   Koch, Walter J ^c   Hajnóczky, György ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

Alcohol; Calcium; Cardiomyopathy; Fusion; Mitochondria

Indexed keywords

ADENOVIRUS VECTOR; CALCIUM; GREEN FLUORESCENT PROTEIN; MITOFUSIN 1; RYANODINE RECEPTOR 2; VERAPAMIL; PHOTOPROTEIN;

ADULT; ALCOHOLIC CARDIOMYOPATHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; CALCIUM SIGNALING; CARDIAC MUSCLE CELL; CELL CULTURE; CELL FUSION; CELL ISOLATION; CONFERENCE PAPER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENETIC TRANSDUCTION; HEART MUSCLE CONTRACTILITY; HEK293 CELL LINE; IN VIVO STUDY; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; NONHUMAN; PATHOGENESIS; PHOTOACTIVATION; PRIORITY JOURNAL; RAT; ANIMAL; CELL LINE; GENE VECTOR; GENETICS; HEART CONTRACTION; HEART MITOCHONDRION; HUMAN; PHYSIOLOGY; REPORTER GENE; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; CALCIUM SIGNALING; CELL LINE; GENES, REPORTER; GENETIC VECTORS; HUMANS; LUMINESCENT PROTEINS; MALE; MICROSCOPY, CONFOCAL; MITOCHONDRIA, HEART; MITOCHONDRIAL DYNAMICS; MYOCARDIAL CONTRACTION; RATS; RATS, SPRAGUE-DAWLEY; TRANSDUCTION, GENETIC;

EID: 85010992004     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1617288114     Document Type: Article

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