Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence

PLoS Pathogens

Volumn 13, Issue 1, 2017, Pages

  Robb, Melissa ^a,e   Hobbs, Joanne K ^a   Woodiga, Shireen A ^b   Shapiro Ward, Sarah ^a   Suits, Michael D L ^a,f   McGregor, Nicholas ^c   Brumer, Harry ^c   Yesilkaya, Hasan ^d   King, Samantha J ^b   Boraston, Alisdair B ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

^e MAX PLANCK INSTITUTE FOR MARINE MICROBIOLOGY   (Germany)

^f WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ALPHA MANNOSIDASE; GLYCAN; N ACETYL BETA GLUCOSAMINIDASE; BACTERIAL PROTEIN; GLYCOSIDASE; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM CULTURE; BINDING AFFINITY; BLOOD ANALYSIS; CONTROLLED STUDY; GENE LOCUS; HIGH THROUGHPUT SCREENING; HOST PATHOGEN INTERACTION; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; ISOTHERMAL TITRATION CALORIMETRY; MICROARRAY ANALYSIS; MICROBIAL DEGRADATION; NONHUMAN; PHOTON CORRELATION SPECTROSCOPY; PNEUMONIA; PROTEIN EXPRESSION; PROTEIN GLYCOSYLATION; PROTEIN PURIFICATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SIZE EXCLUSION CHROMATOGRAPHY; STREPTOCOCCUS PNEUMONIAE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY; ANIMAL; DISEASE MODEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MOUSE; PATHOGENICITY; PHYSIOLOGY; PNEUMOCOCCAL INFECTION; VIRULENCE;

ANIMALS; BACTERIAL PROTEINS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLOGRAPHY, X-RAY; DISEASE MODELS, ANIMAL; GLYCOSIDE HYDROLASES; HOST-PATHOGEN INTERACTIONS; MICE; PNEUMOCOCCAL INFECTIONS; POLYSACCHARIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; VIRULENCE;

EID: 85010977521     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006090     Document Type: Article

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