Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence

Infection and Immunity

Volumn 77, Issue 12, 2009, Pages 5418-5427

  Yesilkaya, Hasan ^a   Spissu, Francesca ^a   Carvalho, Sandra M ^b   Terra, Vanessa S ^a   Homer, Karen A ^c   Benisty, Rachel ^d   Porat, Nurith ^d   Neves, Ana R ^b   Andrew, Peter W ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; FATTY ACID; FORMATE ACETYLTRANSFERASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GALACTOSE; GLUCOSE; LYASE; PYRUVATE KINASE; UNCLASSIFIED DRUG;

ANAEROBIC GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; BACTERIUM MUTANT; COLONY FORMING UNIT; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ANALYSIS; ENZYME MECHANISM; FEMALE; FERMENTATION; GENE EXPRESSION; GENE MUTATION; GENETIC REGULATION; LIPID COMPOSITION; LUNG; MOUSE; NASOPHARYNX; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; PROTEIN FUNCTION; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME; UPREGULATION; WILD TYPE;

ACETYLTRANSFERASES; ANAEROBIOSIS; ANIMALS; BACTEREMIA; BACTERIAL PROTEINS; COLONY COUNT, MICROBIAL; FATTY ACIDS; FEMALE; FERMENTATION; FORMIC ACIDS; GALACTOSE; GENE DELETION; GLUCOSE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICROBIAL VIABILITY; MODELS, BIOLOGICAL; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; VIRULENCE;

EID: 72449165859     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00178-09     Document Type: Article

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