A second β-hexosaminidase encoded in the streptococcus pneumoniae genome provides an expanded biochemical ability to degrade host glycans

Journal of Biological Chemistry

Volumn 290, Issue 52, 2015, Pages 30888-30900

  Robb, Melissa ^a   Robb, Craig S ^a   Higgins, Melanie A ^b,c   Hobbs, Joanne K ^a   Paton, James C ^b   Boraston, Alisdair B ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIODEGRADATION; ENZYMES; PLANTS (BOTANY); POLYSACCHARIDES; SUGARS;

GLYCOSIDE HYDROLASES; INHIBITION CONSTANTS; N-ACETYL-D-GALACTOSAMINE; N-ACETYL-D-GLUCOSAMINE; N-ACETYLGLUCOSAMINE; N-ACETYLHEXOSAMINIDASE; STREPTOCOCCUS PNEUMONIAE; X RAY CRYSTAL STRUCTURES;

HYDROLASES;

AGLYCONE; BETA N ACETYLHEXOSAMINIDASE; CARBAMIC ACID DERIVATIVE; FAMILY 20 GLYCOSIDE HYDROLASE; GLYCAN; GLYCOSIDASE; N ACETYL DEXTRO GALACTOSAMINE THIAZOLINE; N ACETYL DEXTRO GLUCOSAMINE THIAZOLINE; N ACETYLGALACTOSAMINE; N ACETYLGLUCOSAMINE; O (2 ACETAMIDO 2 DEOXY DEXTRO GALACTOPYRANOSYLIDENE)AMINO N PHENYL CARBAMATE; O (2 ACETAMIDO 2 DEOXY DEXTRO GLUCOPYRANOSYLIDENE)AMINO N PHENYL CARBAMATE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; POLYSACCHARIDE;

ARTICLE; BACTERIAL GENOME; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEGRADATION; ENZYME ANALYSIS; HOST PATHOGEN INTERACTION; HYDROLYSIS; IN VITRO STUDY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BETA-N-ACETYLHEXOSAMINIDASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; GENOME, BACTERIAL; HUMANS; POLYSACCHARIDES; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS PNEUMONIAE;

EID: 84951768903     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.688630     Document Type: Article

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