메뉴 건너뛰기




Volumn 215, Issue , 2017, Pages 23-29

Lessons from the genomes and transcriptomes of filarial nematodes

Author keywords

Filaria; Genomics; Parasitic nematodes; Transcriptomics

Indexed keywords

PROTEIN KINASE; VACCINE; TRANSCRIPTOME;

EID: 85010952890     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2017.01.004     Document Type: Article
Times cited : (10)

References (59)
  • 1
    • 84905507693 scopus 로고    scopus 로고
    • The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases
    • Hotez, P.J., et al. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl. Trop. Dis., 8(7), 2014, e2865.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , Issue.7 , pp. e2865
    • Hotez, P.J.1
  • 2
    • 84994092049 scopus 로고    scopus 로고
    • Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
    • Disease, G.B.D., Injury, I., Prevalence, C., Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet 388:10053 (2016), 1545–1602.
    • (2016) Lancet , vol.388 , Issue.10053 , pp. 1545-1602
    • Disease, G.B.D.1    Injury, I.2    Prevalence, C.3
  • 3
    • 0014859385 scopus 로고
    • Development of Brugia pahangi in the jird Meriones unguiculatus, with notes on infections in other rodents
    • Ash, L.R., Riley, J.M., Development of Brugia pahangi in the jird Meriones unguiculatus, with notes on infections in other rodents. J. Parasitol. 56:5 (1970), 962–968.
    • (1970) J. Parasitol. , vol.56 , Issue.5 , pp. 962-968
    • Ash, L.R.1    Riley, J.M.2
  • 4
    • 0015879102 scopus 로고
    • Chronic Brugia pahangi and Brugia malayi infections in Meriones unguiculatus
    • Ash, L.R., Chronic Brugia pahangi and Brugia malayi infections in Meriones unguiculatus. J. Parasitol. 59:3 (1973), 442–447.
    • (1973) J. Parasitol. , vol.59 , Issue.3 , pp. 442-447
    • Ash, L.R.1
  • 5
    • 0015852551 scopus 로고
    • Worm burdens and prepatent periods in jirds (Meriones unguiculatus) infected with Brugia malayi
    • el-Bihari, S., Ewert, A., Worm burdens and prepatent periods in jirds (Meriones unguiculatus) infected with Brugia malayi. Southeast Asian J. Trop. Med. Public Health 4:2 (1973), 184–186.
    • (1973) Southeast Asian J. Trop. Med. Public Health , vol.4 , Issue.2 , pp. 184-186
    • el-Bihari, S.1    Ewert, A.2
  • 6
    • 84882568608 scopus 로고    scopus 로고
    • Development of a facile system for mass production of Brugia malayi in a small-space laboratory
    • Saeung, A., Choochote, W., Development of a facile system for mass production of Brugia malayi in a small-space laboratory. Parasitol. Res. 112:9 (2013), 3259–3265.
    • (2013) Parasitol. Res. , vol.112 , Issue.9 , pp. 3259-3265
    • Saeung, A.1    Choochote, W.2
  • 7
    • 84996538227 scopus 로고    scopus 로고
    • The genome of Onchocerca volvulus, agent of river blindness
    • Cotton, J.A., et al. The genome of Onchocerca volvulus, agent of river blindness. Nat. Microbiol., 2, 2016, 16216.
    • (2016) Nat. Microbiol. , vol.2 , pp. 16216
    • Cotton, J.A.1
  • 8
    • 84878534378 scopus 로고    scopus 로고
    • Genomics of Loa loa, a Wolbachia-free filarial parasite of humans
    • Desjardins, C.A., et al. Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Nat. Genet. 45:5 (2013), 495–500.
    • (2013) Nat. Genet. , vol.45 , Issue.5 , pp. 495-500
    • Desjardins, C.A.1
  • 9
    • 84941135183 scopus 로고    scopus 로고
    • Draft genome of Brugia pahangi: high similarity between B. pahangi and B. malayi
    • Lau, Y.L., et al. Draft genome of Brugia pahangi: high similarity between B. pahangi and B. malayi. Parasites Vectors, 8, 2015, 451.
    • (2015) Parasites Vectors , vol.8 , pp. 451
    • Lau, Y.L.1
  • 10
    • 84868274725 scopus 로고    scopus 로고
    • The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets
    • Godel, C., et al. The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. FASEB J. 26:11 (2012), 4650–4661.
    • (2012) FASEB J. , vol.26 , Issue.11 , pp. 4650-4661
    • Godel, C.1
  • 11
    • 84901594241 scopus 로고    scopus 로고
    • A lack of parasitic reduction in the obligate parasitic green alga Helicosporidium
    • Pombert, J.F., et al. A lack of parasitic reduction in the obligate parasitic green alga Helicosporidium. PLoS Genet., 10(5), 2014, e1004355.
    • (2014) PLoS Genet. , vol.10 , Issue.5 , pp. e1004355
    • Pombert, J.F.1
  • 12
    • 34648836102 scopus 로고    scopus 로고
    • Draft genome of the filarial nematode parasite Brugia malayi
    • Ghedin, E., et al. Draft genome of the filarial nematode parasite Brugia malayi. Science 317:5845 (2007), 1756–1760.
    • (2007) Science , vol.317 , Issue.5845 , pp. 1756-1760
    • Ghedin, E.1
  • 13
    • 79952195648 scopus 로고    scopus 로고
    • The draft genome of the parasitic nematode Trichinella spiralis
    • Mitreva, M., et al. The draft genome of the parasitic nematode Trichinella spiralis. Nat. Genet. 43:3 (2011), 228–235.
    • (2011) Nat. Genet. , vol.43 , Issue.3 , pp. 228-235
    • Mitreva, M.1
  • 14
    • 38549180634 scopus 로고    scopus 로고
    • Nematode genome evolution
    • Coghlan, A., Nematode genome evolution. WormBook, 2005: p. 1–15.
    • (2005) WormBook , pp. 1-15
    • Coghlan, A.1
  • 15
    • 0023133965 scopus 로고
    • Chromosomes of Onchocerca volvulus (Spirurida: Onchocercidae): a comparative study between Nigeria and Guatemala
    • Hirai, H., et al. Chromosomes of Onchocerca volvulus (Spirurida: Onchocercidae): a comparative study between Nigeria and Guatemala. J. Helminthol. 61:1 (1987), 43–46.
    • (1987) J. Helminthol. , vol.61 , Issue.1 , pp. 43-46
    • Hirai, H.1
  • 16
    • 0033525845 scopus 로고    scopus 로고
    • Identification of a molecular marker for the Y chromosome of Brugia malayi
    • Underwood, A.P., Bianco, A.E., Identification of a molecular marker for the Y chromosome of Brugia malayi. Mol. Biochem. Parasitol. 99:1 (1999), 1–10.
    • (1999) Mol. Biochem. Parasitol. , vol.99 , Issue.1 , pp. 1-10
    • Underwood, A.P.1    Bianco, A.E.2
  • 17
    • 0003764187 scopus 로고
    • 3d ed. University Press Cambridge, Eng (961 p.)
    • White, M.J.D., 3d ed. Animal Cytology and Evolution, Vol. viii, 1973, University Press, Cambridge, Eng (961 p.).
    • (1973) Animal Cytology and Evolution , vol.8
    • White, M.J.D.1
  • 18
    • 27844602007 scopus 로고    scopus 로고
    • The chromosomes of the Filariae
    • Post, R., The chromosomes of the Filariae. Filaria J., 4, 2005, 10.
    • (2005) Filaria J. , vol.4 , pp. 10
    • Post, R.1
  • 19
    • 0022642002 scopus 로고
    • Gametogenesis and fertilization in Dirofilaria immitis (Nematoda: Filarioidea)
    • Delves, C.J., Howells, R.E., Post, R.J., Gametogenesis and fertilization in Dirofilaria immitis (Nematoda: Filarioidea). Parasitology 92:Pt 1 (1986), 181–197.
    • (1986) Parasitology , vol.92 , pp. 181-197
    • Delves, C.J.1    Howells, R.E.2    Post, R.J.3
  • 20
    • 0020963292 scopus 로고
    • Karyotypes of Brugia pahangi and Brugia malayi (Nematoda: Filarioidea)
    • Sakaguchi, Y., et al. Karyotypes of Brugia pahangi and Brugia malayi (Nematoda: Filarioidea). J. Parasitol. 69:6 (1983), 1090–1093.
    • (1983) J. Parasitol. , vol.69 , Issue.6 , pp. 1090-1093
    • Sakaguchi, Y.1
  • 21
    • 0013966914 scopus 로고
    • Observations on spermatogenesis in Onchocerca volvulus and Wuchereria bancrofti
    • Miller, M.J., Observations on spermatogenesis in Onchocerca volvulus and Wuchereria bancrofti. Can. J. Zool. 44:6 (1966), 1003–1006.
    • (1966) Can. J. Zool. , vol.44 , Issue.6 , pp. 1003-1006
    • Miller, M.J.1
  • 22
    • 0024422884 scopus 로고
    • Chromosomes of six species of Onchocerca (Nematoda: Filarioidea)
    • Post, R.J., et al. Chromosomes of six species of Onchocerca (Nematoda: Filarioidea). Trop. Med. Parasitol. 40:3 (1989), 292–294.
    • (1989) Trop. Med. Parasitol. , vol.40 , Issue.3 , pp. 292-294
    • Post, R.J.1
  • 23
    • 0025867029 scopus 로고
    • Chromosome numbers in Onchocerca dukei and O. tarsicola
    • Post, R.J., Bain, O., Klager, S., Chromosome numbers in Onchocerca dukei and O. tarsicola. J. Helminthol. 65:3 (1991), 208–210.
    • (1991) J. Helminthol. , vol.65 , Issue.3 , pp. 208-210
    • Post, R.J.1    Bain, O.2    Klager, S.3
  • 24
    • 26844459599 scopus 로고    scopus 로고
    • Wolbachia bacterial endosymbionts of filarial nematodes
    • Taylor, M.J., Bandi, C., Hoerauf, A., Wolbachia bacterial endosymbionts of filarial nematodes. Adv. Parasitol. 60 (2005), 245–284.
    • (2005) Adv. Parasitol. , vol.60 , pp. 245-284
    • Taylor, M.J.1    Bandi, C.2    Hoerauf, A.3
  • 25
    • 21144432943 scopus 로고    scopus 로고
    • The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode
    • Foster, J., et al. The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode. PLoS Biol., 3(4), 2005, e121.
    • (2005) PLoS Biol. , vol.3 , Issue.4 , pp. e121
    • Foster, J.1
  • 26
    • 84868113800 scopus 로고    scopus 로고
    • Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis
    • Darby, A.C., et al. Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis. Genome Res. 22:12 (2012), 2467–2477.
    • (2012) Genome Res. , vol.22 , Issue.12 , pp. 2467-2477
    • Darby, A.C.1
  • 27
    • 77955265557 scopus 로고    scopus 로고
    • Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer
    • McNulty, S.N., et al. Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer. PLoS One, 5(6), 2010, e11029.
    • (2010) PLoS One , vol.5 , Issue.6 , pp. e11029
    • McNulty, S.N.1
  • 28
    • 84884308327 scopus 로고    scopus 로고
    • Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi
    • Ioannidis, P., et al. Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi. BMC Genom. 14:1 (2013), 1–17.
    • (2013) BMC Genom. , vol.14 , Issue.1 , pp. 1-17
    • Ioannidis, P.1
  • 29
    • 84928713006 scopus 로고    scopus 로고
    • Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression
    • Luck, A.N., et al. Concurrent transcriptional profiling of Dirofilaria immitis and its Wolbachia endosymbiont throughout the nematode life cycle reveals coordinated gene expression. BMC Genom., 15, 2014, 1041.
    • (2014) BMC Genom. , vol.15 , pp. 1041
    • Luck, A.N.1
  • 30
    • 84947867268 scopus 로고    scopus 로고
    • Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont
    • Luck, A.N., et al. Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont. BMC Genom., 16, 2015, 920.
    • (2015) BMC Genom. , vol.16 , pp. 920
    • Luck, A.N.1
  • 31
    • 84861220352 scopus 로고    scopus 로고
    • Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni
    • Ingram, J.R., et al. Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni. PLoS Negl. Trop. Dis., 6(4), 2012, e1589.
    • (2012) PLoS Negl. Trop. Dis. , vol.6 , Issue.4 , pp. e1589
    • Ingram, J.R.1
  • 32
    • 80053436285 scopus 로고    scopus 로고
    • Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes
    • Ingram, J., et al. Proteomic analysis of human skin treated with larval schistosome peptidases reveals distinct invasion strategies among species of blood flukes. PLoS Negl. Trop. Dis., 5(9), 2011, e1337.
    • (2011) PLoS Negl. Trop. Dis. , vol.5 , Issue.9 , pp. e1337
    • Ingram, J.1
  • 33
    • 84897427611 scopus 로고    scopus 로고
    • Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni- ‘the undiscovered country’
    • Horn, M., et al. Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni- ‘the undiscovered country’. PLoS Negl. Trop. Dis., 8(3), 2014, e2766.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , Issue.3 , pp. e2766
    • Horn, M.1
  • 34
    • 57449101334 scopus 로고    scopus 로고
    • The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti
    • Doleckova, K., et al. The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti. Int. J. Parasitol. 39:2 (2009), 201–211.
    • (2009) Int. J. Parasitol. , vol.39 , Issue.2 , pp. 201-211
    • Doleckova, K.1
  • 35
    • 85007550882 scopus 로고    scopus 로고
    • Stage-specific transcriptome and proteome analyses of the filarial parasite Onchocerca volvulus and its Wolbachia endosymbiont
    • Bennuru, S., et al. Stage-specific transcriptome and proteome analyses of the filarial parasite Onchocerca volvulus and its Wolbachia endosymbiont. MBio, 7(6), 2016.
    • (2016) MBio , vol.7 , Issue.6
    • Bennuru, S.1
  • 36
    • 8844224148 scopus 로고    scopus 로고
    • RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting
    • Lustigman, S., et al. RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting. Mol. Biochem. Parasitol. 138:2 (2004), 165–170.
    • (2004) Mol. Biochem. Parasitol. , vol.138 , Issue.2 , pp. 165-170
    • Lustigman, S.1
  • 37
    • 2942538289 scopus 로고    scopus 로고
    • A gene family of cathepsin L-like proteases of filarial nematodes are associated with larval molting and cuticle and eggshell remodeling
    • Guiliano, D.B., et al. A gene family of cathepsin L-like proteases of filarial nematodes are associated with larval molting and cuticle and eggshell remodeling. Mol. Biochem. Parasitol. 136:2 (2004), 227–242.
    • (2004) Mol. Biochem. Parasitol. , vol.136 , Issue.2 , pp. 227-242
    • Guiliano, D.B.1
  • 38
    • 78651240094 scopus 로고    scopus 로고
    • Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi
    • Song, C., et al. Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi. PLoS Pathog., 6(12), 2010, e1001239.
    • (2010) PLoS Pathog. , vol.6 , Issue.12 , pp. e1001239
    • Song, C.1
  • 39
    • 77950649023 scopus 로고    scopus 로고
    • Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi
    • (p)
    • Kariuki, M.M., Hearne, L.B., Beerntsen, B.T., Differential transcript expression between the microfilariae of the filarial nematodes, Brugia malayi and B. pahangi. BMC Genom., 11, 2010, 225 (p).
    • (2010) BMC Genom. , vol.11 , pp. 225
    • Kariuki, M.M.1    Hearne, L.B.2    Beerntsen, B.T.3
  • 40
    • 28844497908 scopus 로고    scopus 로고
    • Characterization of a novel filarial serine protease inhibitor: Ov-SPI-1, from Onchocerca volvulus, with potential multifunctional roles during development of the parasite
    • Ford, L., et al. Characterization of a novel filarial serine protease inhibitor: Ov-SPI-1, from Onchocerca volvulus, with potential multifunctional roles during development of the parasite. J. Biol. Chem. 280:49 (2005), 40845–40856.
    • (2005) J. Biol. Chem. , vol.280 , Issue.49 , pp. 40845-40856
    • Ford, L.1
  • 41
    • 0034981964 scopus 로고    scopus 로고
    • Immune evasion genes from filarial nematodes
    • Maizels, R.M., et al. Immune evasion genes from filarial nematodes. Int. J. Parasitol. 31:9 (2001), 889–898.
    • (2001) Int. J. Parasitol. , vol.31 , Issue.9 , pp. 889-898
    • Maizels, R.M.1
  • 42
    • 84943327423 scopus 로고    scopus 로고
    • Targeting filarial Abl-like kinases: orally available, food and drug administration-approved tyrosine kinase inhibitors are microfilaricidal and macrofilaricidal
    • O'Connell, E.M., et al. Targeting filarial Abl-like kinases: orally available, food and drug administration-approved tyrosine kinase inhibitors are microfilaricidal and macrofilaricidal. J. Infect. Dis. 212:5 (2015), 684–693.
    • (2015) J. Infect. Dis. , vol.212 , Issue.5 , pp. 684-693
    • O'Connell, E.M.1
  • 43
    • 58549108388 scopus 로고    scopus 로고
    • Reconstruction of biochemical networks in microorganisms
    • Feist, A.M., et al. Reconstruction of biochemical networks in microorganisms. Nat. Rev. Microbiol. 7:2 (2009), 129–143.
    • (2009) Nat. Rev. Microbiol. , vol.7 , Issue.2 , pp. 129-143
    • Feist, A.M.1
  • 44
    • 84888149629 scopus 로고    scopus 로고
    • Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii
    • Song, C., et al. Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii. Mol. Syst. Biol., 9, 2013, 708.
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 708
    • Song, C.1
  • 45
    • 84924106975 scopus 로고    scopus 로고
    • Systems-based analysis of the Sarcocystis neurona genome identifies pathways that contribute to a heteroxenous life cycle
    • Blazejewski, T., et al. Systems-based analysis of the Sarcocystis neurona genome identifies pathways that contribute to a heteroxenous life cycle. MBio, 6(1), 2015.
    • (2015) MBio , vol.6 , Issue.1
    • Blazejewski, T.1
  • 46
  • 47
    • 77956456621 scopus 로고    scopus 로고
    • Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis
    • Huthmacher, C., et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. BMC Syst. Biol., 4, 2010, 120.
    • (2010) BMC Syst. Biol. , vol.4 , pp. 120
    • Huthmacher, C.1
  • 48
    • 41149169317 scopus 로고    scopus 로고
    • Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major
    • Chavali, A.K., et al. Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. Mol. Syst. Biol., 4, 2008, 177.
    • (2008) Mol. Syst. Biol. , vol.4 , pp. 177
    • Chavali, A.K.1
  • 49
    • 77649324484 scopus 로고    scopus 로고
    • Schistosomiasis vaccine discovery using immunomics
    • Driguez, P., et al. Schistosomiasis vaccine discovery using immunomics. Parasites Vectors, 3, 2010, 4.
    • (2010) Parasites Vectors , vol.3 , pp. 4
    • Driguez, P.1
  • 50
    • 84897465663 scopus 로고    scopus 로고
    • An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas
    • Gaze, S., et al. An immunomics approach to schistosome antigen discovery: antibody signatures of naturally resistant and chronically infected individuals from endemic areas. PLoS Pathog., 10(3), 2014, e1004033.
    • (2014) PLoS Pathog. , vol.10 , Issue.3 , pp. e1004033
    • Gaze, S.1
  • 51
    • 84895883455 scopus 로고    scopus 로고
    • Genome of the human hookworm Necator americanus
    • Tang, Y.T., et al. Genome of the human hookworm Necator americanus. Nat. Genet. 46:3 (2014), 261–269.
    • (2014) Nat. Genet. , vol.46 , Issue.3 , pp. 261-269
    • Tang, Y.T.1
  • 52
    • 84969961367 scopus 로고    scopus 로고
    • A next-generation proteome array for Schistosoma mansoni
    • de Assis, R.R., et al. A next-generation proteome array for Schistosoma mansoni. Int. J. Parasitol. 46:7 (2016), 411–415.
    • (2016) Int. J. Parasitol. , vol.46 , Issue.7 , pp. 411-415
    • de Assis, R.R.1
  • 53
    • 84855167015 scopus 로고    scopus 로고
    • Computational vaccinology: an important strategy to discover new potential S. mansoni vaccine candidates
    • Pinheiro, C.S., et al. Computational vaccinology: an important strategy to discover new potential S. mansoni vaccine candidates. J. Biomed. Biotechnol., 2011, 503068.
    • (2011) J. Biomed. Biotechnol. , pp. 503068
    • Pinheiro, C.S.1
  • 54
    • 84939445609 scopus 로고    scopus 로고
    • The case for vaccine development in the strategy to eradicate river blindness (onchocerciasis) from Africa
    • Makepeace, B.L., et al. The case for vaccine development in the strategy to eradicate river blindness (onchocerciasis) from Africa. Expert Rev. Vaccines 14:9 (2015), 1163–1165.
    • (2015) Expert Rev. Vaccines , vol.14 , Issue.9 , pp. 1163-1165
    • Makepeace, B.L.1
  • 55
    • 0036498233 scopus 로고    scopus 로고
    • Towards a recombinant antigen vaccine against Onchocerca volvulus
    • Lustigman, S., et al. Towards a recombinant antigen vaccine against Onchocerca volvulus. Trends Parasitol. 18:3 (2002), 135–141.
    • (2002) Trends Parasitol. , vol.18 , Issue.3 , pp. 135-141
    • Lustigman, S.1
  • 56
    • 84880035622 scopus 로고    scopus 로고
    • Anti-filarial Vaccine Development: Present and Future Approaches
    • R. Conor Caffrey First Edition Wiley-VCH Verlag GmbH & Co. KGaA
    • Lustigman, S., et al. Anti-filarial Vaccine Development: Present and Future Approaches. Conor Caffrey, R., (eds.) Parasitic Helminths: Targets, Screens, Drugs and Vaccines, First Edition, 2012, Wiley-VCH Verlag GmbH & Co. KGaA.
    • (2012) Parasitic Helminths: Targets, Screens, Drugs and Vaccines
    • Lustigman, S.1
  • 58
    • 0842283890 scopus 로고    scopus 로고
    • Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae
    • Abraham, D., et al. Immunoglobulin E and eosinophil-dependent protective immunity to larval Onchocerca volvulus in mice immunized with irradiated larvae. Infect. Immun. 72:2 (2004), 810–817.
    • (2004) Infect. Immun. , vol.72 , Issue.2 , pp. 810-817
    • Abraham, D.1
  • 59
    • 84862856774 scopus 로고    scopus 로고
    • Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths
    • (e6)
    • Diemert, D.J., et al. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J. Allergy Clin. Immunol. 130:1 (2012), 169–176 (e6).
    • (2012) J. Allergy Clin. Immunol. , vol.130 , Issue.1 , pp. 169-176
    • Diemert, D.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.