메뉴 건너뛰기




Volumn 34, Issue 3, 2017, Pages 746-754

High-mobility group box 1 (HMGB1) is elevated systemically in persons with acute or chronic traumatic spinal cord injury

Author keywords

damage associated molecular pattern; high mobility group box 1; inflammation; spinal cord injury

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; STEROID; BIOLOGICAL MARKER; HMGB1 PROTEIN, HUMAN;

EID: 85010796578     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2016.4596     Document Type: Article
Times cited : (54)

References (56)
  • 1
    • 85010779573 scopus 로고    scopus 로고
    • National Spinal Cord Injury Statistical Center. University of Alabama: Birmingham
    • National Spinal Cord Injury Statistical Center. (2016). Spinal Cord Injury (SCI) Facts, and Figures at a Glance. University of Alabama: Birmingham
    • (2016) Spinal Cord Injury (SCI) Facts, and Figures at A Glance
  • 2
    • 84904768726 scopus 로고    scopus 로고
    • The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury
    • Schwab, J.M., Zhang, Y., Kopp, M.A., Brommer, B., and Popovich, P.G. (2014). The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury. Exp. Neurol. 258, 121-129
    • (2014) Exp. Neurol , vol.258 , pp. 121-129
    • Schwab, J.M.1    Zhang, Y.2    Kopp, M.A.3    Brommer, B.4    Popovich, P.G.5
  • 4
    • 79952798014 scopus 로고    scopus 로고
    • Inflammatory, and structural biomarkers in acute traumatic spinal cord injury
    • Kwon, B.K., Casha, S., Hurlbert, R.J., and Yong, V.W. (2011). Inflammatory, and structural biomarkers in acute traumatic spinal cord injury. Clin. Chem. Lab. Med. 49, 425-433
    • (2011) Clin. Chem. Lab. Med , vol.49 , pp. 425-433
    • Kwon, B.K.1    Casha, S.2    Hurlbert, R.J.3    Yong, V.W.4
  • 6
    • 84925626720 scopus 로고    scopus 로고
    • Elevated circulating levels of the pro-inflammatory cytokine macrophage migration inhibitory factor in individuals with acute spinal cord injury
    • Bank, M., Stein, A., Sison, C., Glazer, A., Jassal, N., McCarthy, D., Shatzer, M., Hahn, B., Chugh, R., Davies, P., and Bloom, O. (2015). Elevated circulating levels of the pro-inflammatory cytokine macrophage migration inhibitory factor in individuals with acute spinal cord injury. Arch. Phys. Med. Rehabil. 96, 633-644
    • (2015) Arch. Phys. Med. Rehabil , vol.96 , pp. 633-644
    • Bank, M.1    Stein, A.2    Sison, C.3    Glazer, A.4    Jassal, N.5    McCarthy, D.6    Shatzer, M.7    Hahn, B.8    Chugh, R.9    Davies, P.10    Bloom, O.11
  • 7
    • 84876273574 scopus 로고    scopus 로고
    • B-cell maturation antigen, a proliferation-inducing ligand, and B-cell activating factor are candidate mediators of spinal cord injury-induced autoimmunity
    • Saltzman, J.W., Battaglino, R., Salles, L., Jha, P., Sudhakar, S., Garshick, E., Stott, H.L., Zafonte, R., and Morse, L.R. (2012). B-cell maturation antigen, a proliferation-inducing ligand, and B-cell activating factor are candidate mediators of spinal cord injury-induced autoimmunity. J. Neurotrauma 30, 434-440
    • (2012) J. Neurotrauma , vol.30 , pp. 434-440
    • Saltzman, J.W.1    Battaglino, R.2    Salles, L.3    Jha, P.4    Sudhakar, S.5    Garshick, E.6    Stott, H.L.7    Zafonte, R.8    Morse, L.R.9
  • 8
    • 0036311119 scopus 로고    scopus 로고
    • Elevated serum titers of proinflammatory cytokines, and CNS autoantibodies in patients with chronic spinal cord injury
    • Hayes, K.C., Hull, T.C., Delaney, G.A., Potter, P.J., Sequeira, K.A., Campbell, K., and Popovich, P.G. (2002). Elevated serum titers of proinflammatory cytokines, and CNS autoantibodies in patients with chronic spinal cord injury. J. Neurotrauma 19, 753-761
    • (2002) J. Neurotrauma , vol.19 , pp. 753-761
    • Hayes, K.C.1    Hull, T.C.2    Delaney, G.A.3    Potter, P.J.4    Sequeira, K.A.5    Campbell, K.6    Popovich, P.G.7
  • 9
    • 84880923779 scopus 로고    scopus 로고
    • Pilot study: Elevated circulating levels of the proinflammatory cytokine macrophage migration inhibitory factor in patients with chronic spinal cord injury
    • Stein, A., Panjwani, A., Sison, C., Rosen, L., Chugh, R., Metz, C., Bank, M., and Bloom, O. (2013). Pilot study: elevated circulating levels of the proinflammatory cytokine macrophage migration inhibitory factor in patients with chronic spinal cord injury. Arch. Phys. Med. Rehabil. 94, 1498-1507
    • (2013) Arch. Phys. Med. Rehabil , vol.94 , pp. 1498-1507
    • Stein, A.1    Panjwani, A.2    Sison, C.3    Rosen, L.4    Chugh, R.5    Metz, C.6    Bank, M.7    Bloom, O.8
  • 11
    • 35448987983 scopus 로고    scopus 로고
    • Clinical correlates of elevated serum concentrations of cytokines, and autoantibodies in patients with spinal cord injury
    • Davies, A.L., Hayes, K.C., and Dekaban, G.A. (2007). Clinical correlates of elevated serum concentrations of cytokines, and autoantibodies in patients with spinal cord injury. Arch. Phys. Med. Rehabil. 88, 1384-1393
    • (2007) Arch. Phys. Med. Rehabil , vol.88 , pp. 1384-1393
    • Davies, A.L.1    Hayes, K.C.2    Dekaban, G.A.3
  • 12
    • 13444271845 scopus 로고    scopus 로고
    • Inflammatory C-reactive protein, and cytokine levels in asymptomatic people with chronic spinal cord injury
    • Frost, F., Roach, M.J., Kushner, I., and Schreiber, P. (2005). Inflammatory C-reactive protein, and cytokine levels in asymptomatic people with chronic spinal cord injury. Arch. Phys. Med. Rehabil. 86, 312-317
    • (2005) Arch. Phys. Med. Rehabil , vol.86 , pp. 312-317
    • Frost, F.1    Roach, M.J.2    Kushner, I.3    Schreiber, P.4
  • 13
    • 84893067621 scopus 로고    scopus 로고
    • Spinal cord injury: How can we improve the classification, and quantification of its severity, and prognosis?
    • Krishna, V., Andrews, H., Varma, A., Mintzer, J., Kindy, M.S., and Guest, J. (2014). Spinal cord injury: how can we improve the classification, and quantification of its severity, and prognosis? J. Neurotrauma 31, 215-227
    • (2014) J. Neurotrauma , vol.31 , pp. 215-227
    • Krishna, V.1    Andrews, H.2    Varma, A.3    Mintzer, J.4    Kindy, M.S.5    Guest, J.6
  • 15
    • 84870266144 scopus 로고    scopus 로고
    • High-mobility group box-1 induces proinflammatory cytokines production of Kupffer cells through TLRsdependent signaling pathway after burn injury
    • Chen, X.L., Sun, L., Guo, F., Wang, F., Liu, S., Liang, X., Wang, R.S., Wang, Y.J., and Sun, Y.X. (2012). High-mobility group box-1 induces proinflammatory cytokines production of Kupffer cells through TLRsdependent signaling pathway after burn injury. PLoS One 7, e50668
    • (2012) Plos One , vol.7 , pp. e50668
    • Chen, X.L.1    Sun, L.2    Guo, F.3    Wang, F.4    Liu, S.5    Liang, X.6    Wang, R.S.7    Wang, Y.J.8    Sun, Y.X.9
  • 17
    • 84868273388 scopus 로고    scopus 로고
    • Elevated plasma high-mobility group box 1 protein is a potential marker for neuromyelitis optica
    • Wang, K.C., Tsai, C.P., Lee, C.L., Chen, S.Y., Chin, L.T., and Chen, S.J. (2012). Elevated plasma high-mobility group box 1 protein is a potential marker for neuromyelitis optica. Neuroscience 226, 510-516
    • (2012) Neuroscience , vol.226 , pp. 510-516
    • Wang, K.C.1    Tsai, C.P.2    Lee, C.L.3    Chen, S.Y.4    Chin, L.T.5    Chen, S.J.6
  • 18
    • 84864469515 scopus 로고    scopus 로고
    • Plasma high-mobility group box 1 levels, and prediction of outcome in patients with traumatic brain injury
    • Wang, K.Y., Yu, G.F., Zhang, Z.Y., Huang, Q., and Dong, X.Q. (2012). Plasma high-mobility group box 1 levels, and prediction of outcome in patients with traumatic brain injury. Clin. Chim. Acta 413, 1737-1741
    • (2012) Clin. Chim. Acta , vol.413 , pp. 1737-1741
    • Wang, K.Y.1    Yu, G.F.2    Zhang, Z.Y.3    Huang, Q.4    Dong, X.Q.5
  • 19
    • 84878408642 scopus 로고    scopus 로고
    • The many faces of HMGB1: Molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
    • Yang, H., Antoine, D.J., Andersson, U., and Tracey, K.J. (2013). The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis. J. Leukoc. Biol. 93, 865-873
    • (2013) J. Leukoc. Biol , vol.93 , pp. 865-873
    • Yang, H.1    Antoine, D.J.2    Andersson, U.3    Tracey, K.J.4
  • 20
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): Nuclear weapon in the immune arsenal
    • Lotze, M.T., and Tracey, K.J. (2005). High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 5, 331-342
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 22
    • 84911156693 scopus 로고    scopus 로고
    • The functions of HMGB1 depend on molecular localization, and post-translational modifications
    • Andersson, U., Antoine, D.J, and Tracey, K.J. (2014). The functions of HMGB1 depend on molecular localization, and post-translational modifications. J. Int. Med. 276, 420-424
    • (2014) J. Int. Med , vol.276 , pp. 420-424
    • Andersson, U.1    Antoine, D.J.2    Tracey, K.J.3
  • 23
    • 74449089862 scopus 로고    scopus 로고
    • Targeting HMGB1 in inflammation
    • Yang, H., and Tracey, K.J. (2010). Targeting HMGB1 in inflammation. Biochim. Biophys. Acta 1799, 149-156
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 149-156
    • Yang, H.1    Tracey, K.J.2
  • 24
    • 84903549187 scopus 로고    scopus 로고
    • Disulfidecontaining high mobility group box-1 promotes N-methyl-D-aspartate receptor function, and excitotoxicity by activating Toll-like receptor 4-dependent signaling in hippocampal neurons
    • Balosso, S., Liu, J., Bianchi, M.E., and Vezzani, A. (2014). Disulfidecontaining high mobility group box-1 promotes N-methyl-D-aspartate receptor function, and excitotoxicity by activating Toll-like receptor 4-dependent signaling in hippocampal neurons. Antioxid. Redox. Signal 21, 1726-1740
    • (2014) Antioxid. Redox. Signal , vol.21 , pp. 1726-1740
    • Balosso, S.1    Liu, J.2    Bianchi, M.E.3    Vezzani, A.4
  • 26
    • 84901010218 scopus 로고    scopus 로고
    • Molecular mechanism, and therapeutic modulation of high mobility group box 1 release, and action: An updated review
    • Lu, B., Wang, C., Wang, M., Li, W., Chen, F., Tracey, K.J., and Wang, H. (2014). Molecular mechanism, and therapeutic modulation of high mobility group box 1 release, and action: an updated review. Expert Rev. Clin. Immunol. 10, 713-727
    • (2014) Expert Rev. Clin. Immunol , vol.10 , pp. 713-727
    • Lu, B.1    Wang, C.2    Wang, M.3    Li, W.4    Chen, F.5    Tracey, K.J.6    Wang, H.7
  • 30
    • 84908640980 scopus 로고    scopus 로고
    • High-mobility group box-1 in sterile inflammation
    • Tsung, A., Tohme, S., and Billiar, T.R. (2014). High-mobility group box-1 in sterile inflammation. J. Int. Med. 276, 425-443
    • (2014) J. Int. Med , vol.276 , pp. 425-443
    • Tsung, A.1    Tohme, S.2    Billiar, T.R.3
  • 31
    • 84884702854 scopus 로고    scopus 로고
    • Acute hyperglycemia worsens ischemic stroke-induced brain damage via high mobility group box-1 in rats
    • Huang, J., Liu, B., Yang, C., Chen, H., Eunice, D., and Yuan, Z. (2013). Acute hyperglycemia worsens ischemic stroke-induced brain damage via high mobility group box-1 in rats. Brain Res. 1535, 148-155
    • (2013) Brain Res , vol.1535 , pp. 148-155
    • Huang, J.1    Liu, B.2    Yang, C.3    Chen, H.4    Eunice, D.5    Yuan, Z.6
  • 32
    • 84872068621 scopus 로고    scopus 로고
    • Severe stroke induces long-lasting alterations of high-mobility group box 1
    • Schulze, J., Zierath, D., Tanzi, P., Cain, K., Shibata, D., Dressel, A., and Becker, K. (2013). Severe stroke induces long-lasting alterations of high-mobility group box 1. Stroke 44, 246-248
    • (2013) Stroke , vol.44 , pp. 246-248
    • Schulze, J.1    Zierath, D.2    Tanzi, P.3    Cain, K.4    Shibata, D.5    Dressel, A.6    Becker, K.7
  • 34
    • 84864621433 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of high-mobility group box 1, and cytochrome C predict outcome after pediatric traumatic brain injury
    • Au, A.K., Aneja, R.K., Bell, M.J., Bayir, H., Feldman, K., Adelson, P.D., Fink, E.L., Kochanek, P.M., and Clark, R.S. (2012). Cerebrospinal fluid levels of high-mobility group box 1, and cytochrome C predict outcome after pediatric traumatic brain injury. J. Neurotrauma 29, 2013-2021
    • (2012) J. Neurotrauma , vol.29 , pp. 2013-2021
    • Au, A.K.1    Aneja, R.K.2    Bell, M.J.3    Bayir, H.4    Feldman, K.5    Adelson, P.D.6    Fink, E.L.7    Kochanek, P.M.8    Clark, R.S.9
  • 37
    • 84872269578 scopus 로고    scopus 로고
    • Cerebrospinal fluid high-mobility group box protein 1 in neuromyelitis optica, and multiple sclerosis
    • Wang, H., Wang, K., Wang, C., Xu, F., Zhong, X., Qiu, W., and Hu, X. (2013). Cerebrospinal fluid high-mobility group box protein 1 in neuromyelitis optica, and multiple sclerosis. Neuroimmunomodulation 20, 113-118
    • (2013) Neuroimmunomodulation , vol.20 , pp. 113-118
    • Wang, H.1    Wang, K.2    Wang, C.3    Xu, F.4    Zhong, X.5    Qiu, W.6    Hu, X.7
  • 39
    • 67049132380 scopus 로고    scopus 로고
    • Ethyl pyruvate attenuates spinal cord ischemic injury with a wide therapeutic window through inhibiting highmobility group box 1 release in rabbits
    • Wang, Q., Ding, Q., Zhou, Y., Gou, X., Hou, L., Chen, S., Zhu, Z., and Xiong, L. (2009). Ethyl pyruvate attenuates spinal cord ischemic injury with a wide therapeutic window through inhibiting highmobility group box 1 release in rabbits. Anesthesiology 110, 1279-1286
    • (2009) Anesthesiology , vol.110 , pp. 1279-1286
    • Wang, Q.1    Ding, Q.2    Zhou, Y.3    Gou, X.4    Hou, L.5    Chen, S.6    Zhu, Z.7    Xiong, L.8
  • 40
    • 84855471701 scopus 로고    scopus 로고
    • Glycyrrhizin attenuates rat ischemic spinal cord injury by suppressing inflammatory cytokines, and HMGB1
    • Gong, G., Yuan, L.B., Hu, L., Wu, W., Yin, L., Hou, J.L., Liu, Y.H., and Zhou, L.S. (2012). Glycyrrhizin attenuates rat ischemic spinal cord injury by suppressing inflammatory cytokines, and HMGB1. Acta Pharmacol. Sin 33, 11-18
    • (2012) Acta Pharmacol. Sin , vol.33 , pp. 11-18
    • Gong, G.1    Yuan, L.B.2    Hu, L.3    Wu, W.4    Yin, L.5    Hou, J.L.6    Liu, Y.H.7    Zhou, L.S.8
  • 41
    • 34250182782 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-2, and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury
    • Kigerl, K.A., Lai, W., Rivest, S., Hart, R.P., Satoskar, A.R., and Popovich, P.G. (2007). Toll-like receptor (TLR)-2, and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J. Neurochem. 102, 37-50
    • (2007) J. Neurochem , vol.102 , pp. 37-50
    • Kigerl, K.A.1    Lai, W.2    Rivest, S.3    Hart, R.P.4    Satoskar, A.R.5    Popovich, P.G.6
  • 43
    • 84959107602 scopus 로고    scopus 로고
    • High-throughput proteomics reveal alarmins as amplifiers of tissue pathology, and inflammation after spinal cord injury
    • Didangelos, A., Puglia, M., Iberl, M., Sanchez-Bellot, C., Roschitzki, B., and Bradbury, E.J. (2016). High-throughput proteomics reveal alarmins as amplifiers of tissue pathology, and inflammation after spinal cord injury. Sci. Rep. 6, 21607
    • (2016) Sci. Rep , vol.6 , pp. 21607
    • Didangelos, A.1    Puglia, M.2    Iberl, M.3    Sanchez-Bellot, C.4    Roschitzki, B.5    Bradbury, E.J.6
  • 44
    • 84891560348 scopus 로고    scopus 로고
    • Hyperbaric oxygen alleviates experimental (spinal cord) injury by downregulating HMGB1/NF-kappaB expression
    • Yang, J., Liu, X., Zhou, Y., Wang, G., Gao, C., and Su, Q. (2013). Hyperbaric oxygen alleviates experimental (spinal cord) injury by downregulating HMGB1/NF-kappaB expression. Spine (Phila Pa 1976) 38, E1641-E1648
    • (2013) Spine (Phila Pa 1976 , vol.38 , pp. E1641-E1648
    • Yang, J.1    Liu, X.2    Zhou, Y.3    Wang, G.4    Gao, C.5    Su, Q.6
  • 45
    • 77950817867 scopus 로고    scopus 로고
    • Early release of high mobility group box nuclear protein 1 after severe trauma in humans: Role of injury severity, and tissue hypoperfusion
    • Cohen, M.J., Brohi, K., Calfee, C.S., Rahn, P., Chesebro, B.B., Christiaans, S.C., Carles, M., Howard, M., and Pittet, J.F. (2009). Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity, and tissue hypoperfusion. Crit. Care 13, R174
    • (2009) Crit. Care , vol.13 , pp. R174
    • Cohen, M.J.1    Brohi, K.2    Calfee, C.S.3    Rahn, P.4    Chesebro, B.B.5    Christiaans, S.C.6    Carles, M.7    Howard, M.8    Pittet, J.F.9
  • 46
    • 84938743663 scopus 로고    scopus 로고
    • HMGB1 level in cerebrospinal fluid as a marker of treatment outcome in patients with acute hydrocephalus following aneurysmal subarachnoid hemorrhage
    • Sokol, B., Wozniak, A., Jankowski, R., Jurga, S., Wasik, N., Shahid, H., and Grzeskowiak, B. (2015). HMGB1 level in cerebrospinal fluid as a marker of treatment outcome in patients with acute hydrocephalus following aneurysmal subarachnoid hemorrhage. J. Stroke Cerebrovasc. Dis. 24, 1897-1904
    • (2015) J. Stroke Cerebrovasc. Dis , vol.24 , pp. 1897-1904
    • Sokol, B.1    Wozniak, A.2    Jankowski, R.3    Jurga, S.4    Wasik, N.5    Shahid, H.6    Grzeskowiak, B.7
  • 48
    • 84954039309 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products, and its inflammatory ligands are upregulated in amyotrophic lateral sclerosis
    • Juranek, J.K., Daffu, G.K., Wojtkiewicz, J., Lacomis, D., Kofler, J., and Schmidt, A.M. (2015). Receptor for advanced glycation end products, and its inflammatory ligands are upregulated in amyotrophic lateral sclerosis. Front. Cell Neurosci. 9, 485
    • (2015) Front. Cell Neurosci , vol.9 , pp. 485
    • Juranek, J.K.1    Daffu, G.K.2    Wojtkiewicz, J.3    Lacomis, D.4    Kofler, J.5    Schmidt, A.M.6
  • 49
    • 77952390069 scopus 로고    scopus 로고
    • High mobility group box 1 is upregulated after spinal cord injury, and is associated with neuronal cell apoptosis
    • Kawabata, H., Setoguchi, T., Yone, K., Souda, M., Yoshida, H., Kawahara, K., Maruyama, I., and Komiya, S. (2010). High mobility group box 1 is upregulated after spinal cord injury, and is associated with neuronal cell apoptosis. Spine (Phila Pa 1976) 35, 1109-1115
    • (2010) Spine (Phila Pa 1976 , vol.35 , pp. 1109-1115
    • Kawabata, H.1    Setoguchi, T.2    Yone, K.3    Souda, M.4    Yoshida, H.5    Kawahara, K.6    Maruyama, I.7    Komiya, S.8
  • 51
    • 84898904071 scopus 로고    scopus 로고
    • Genetic ablation of receptor for advanced glycation end products promotes functional recovery in mouse model of spinal cord injury
    • Guo, J.D., Li, L., Shi, Y.M., Wang, H.D., Yuan, Y.L., Shi, X.X., and Hou, S.X. (2014). Genetic ablation of receptor for advanced glycation end products promotes functional recovery in mouse model of spinal cord injury. Mol. Cell. Biochem. 390, 215-223
    • (2014) Mol. Cell. Biochem , vol.390 , pp. 215-223
    • Guo, J.D.1    Li, L.2    Shi, Y.M.3    Wang, H.D.4    Yuan, Y.L.5    Shi, X.X.6    Hou, S.X.7
  • 52
    • 84870845880 scopus 로고    scopus 로고
    • Glycyrrhizin protects rat heart against ischemia-reperfusion injury through blockade of HMGB1-dependent phospho-JNK/Bax pathway
    • Zhai, C.L., Zhang, M.Q., Zhang, Y., Xu, H.X., Wang, J.M., An, G.P., Wang, Y.Y., and Li, L. (2012). Glycyrrhizin protects rat heart against ischemia-reperfusion injury through blockade of HMGB1-dependent phospho-JNK/Bax pathway. Acta Pharmacol. Sin. 33, 1477-1487
    • (2012) Acta Pharmacol. Sin , vol.33 , pp. 1477-1487
    • Zhai, C.L.1    Zhang, M.Q.2    Zhang, Y.3    Xu, H.X.4    Wang, J.M.5    An, G.P.6    Wang, Y.Y.7    Li, L.8
  • 54
    • 42549119565 scopus 로고    scopus 로고
    • Systemic TNF blockade does not modulate synovial expression of the proinflammatory mediator HMGB1 in rheumatoid arthritis patients-a prospective clinical study
    • Sundberg, E., Grundtman, C., Af Klint, E., Lindberg, J., Ernestam, S., Ulfgren, A.K., Harris, H.E., and Andersson, U. (2008). Systemic TNF blockade does not modulate synovial expression of the proinflammatory mediator HMGB1 in rheumatoid arthritis patients-a prospective clinical study. Arthritis Res. Ther. 10, R33
    • (2008) Arthritis Res. Ther , vol.10 , pp. R33
    • Sundberg, E.1    Grundtman, C.2    Af Klint, E.3    Lindberg, J.4    Ernestam, S.5    Ulfgren, A.K.6    Harris, H.E.7    Andersson, U.8
  • 55
    • 84907270248 scopus 로고    scopus 로고
    • Identification of a functional interaction of HMGB1 with receptor for advanced glycation end-products in a model of neuropathic pain
    • Allette, Y.M., Due, M.R., Wilson, S.M., Feldman, P., Ripsch, M.S., Khanna, R., and White, F.A. (2014). Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain. Brain Behav. Immun. 42, 169-177
    • (2014) Brain Behav. Immun , vol.42 , pp. 169-177
    • Allette, Y.M.1    Due, M.R.2    Wilson, S.M.3    Feldman, P.4    Ripsch, M.S.5    Khanna, R.6    White, F.A.7
  • 56
    • 84868359842 scopus 로고    scopus 로고
    • The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain
    • Feldman, P., Due, M.R., Ripsch, M.S., Khanna, R., and White, F.A. (2012). The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain. J. Neuroinflammation 9, 180
    • (2012) J. Neuroinflammation , vol.9 , pp. 180
    • Feldman, P.1    Due, M.R.2    Ripsch, M.S.3    Khanna, R.4    White, F.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.