MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2

eLife

Volumn 6, Issue , 2017, Pages

  Walker, Lauren J ^a   Summers, Daniel W ^a   Sasaki, Yo ^a   Brace, E J ^a   Milbrandt, Jeffrey ^a   DiAntonio, Aaron ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; ARMADILLO DOMAIN PROTEIN; CYTOSKELETON PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NMNAT2 PROTEIN, MOUSE; SARM1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; AXOTOMY; CONTROLLED STUDY; CRISPR CAS SYSTEM; DROSOPHILA; GAIN OF FUNCTION MUTATION; GENE; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; LOSS OF FUNCTION MUTATION; MOUSE; NERVE FIBER DEGENERATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARM1 GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; METABOLISM; NERVE DEGENERATION; PATHOPHYSIOLOGY;

ANIMALS; ARMADILLO DOMAIN PROTEINS; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DROSOPHILA; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NERVE DEGENERATION; NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE; SIGNAL TRANSDUCTION;

EID: 85010637423     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.22540     Document Type: Article

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