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Volumn 5, Issue OCTOBER2016, 2016, Pages

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+depletion

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; COMPLEMENTARY DNA; LENTIVIRUS VECTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE; NICOTINAMIDE NUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINAMIDE RIBOSIDE; SELECTIVE ANDROGEN RECEPTOR MODULATOR; ARMADILLO DOMAIN PROTEIN; CYTOSKELETON PROTEIN; NMNAT1 PROTEIN, MOUSE; SARM1 PROTEIN, MOUSE;

EID: 84991628947     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.19749     Document Type: Article
Times cited : (160)

References (25)
  • 1
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • Araki T, Sasaki Y, Milbrandt J. 2004. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305:1010-1013. doi:10.1126/science.1098014
    • (2004) Science , vol.305 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 3
    • 27644591304 scopus 로고    scopus 로고
    • Axon degeneration mechanisms: Commonality amid diversity
    • Coleman M. 2005. Axon degeneration mechanisms: commonality amid diversity. Nature Reviews Neuroscience 6:889-898. doi:10.1038/nrn1788
    • (2005) Nature Reviews Neuroscience , vol.6 , pp. 889-898
    • Coleman, M.1
  • 4
    • 84901007122 scopus 로고    scopus 로고
    • Wallerian degeneration: An emerging axon death pathway linking injury and disease
    • Conforti L, Gilley J, Coleman MP. 2014. Wallerian degeneration: an emerging axon death pathway linking injury and disease. Nature Reviews Neuroscience 15:394-409. doi:10.1038/nrn3680
    • (2014) Nature Reviews Neuroscience , vol.15 , pp. 394-409
    • Conforti, L.1    Gilley, J.2    Coleman, M.P.3
  • 6
    • 0020058197 scopus 로고
    • Evidence for a physiologically active nicotinamide phosphoribosyltransferase in cultured human fibroblasts
    • Elliott GC, Rechsteiner MC. 1982. Evidence for a physiologically active nicotinamide phosphoribosyltransferase in cultured human fibroblasts. Biochemical and Biophysical Research Communications 104:996-1002. doi:10.1016/0006-291X(82)91348-1
    • (1982) Biochemical and Biophysical Research Communications , vol.104 , pp. 996-1002
    • Elliott, G.C.1    Rechsteiner, M.C.2
  • 7
    • 80051519518 scopus 로고    scopus 로고
    • Image-based screening identifies novel roles for IkappaB kinase and glycogen synthase kinase 3 in axonal degeneration
    • Gerdts J, Sasaki Y, Vohra B, Marasa J, Milbrandt J. 2011. Image-based screening identifies novel roles for IkappaB kinase and glycogen synthase kinase 3 in axonal degeneration. Journal of Biological Chemistry 286: 28011-28018. doi:10.1074/jbc.M111.250472
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 28011-28018
    • Gerdts, J.1    Sasaki, Y.2    Vohra, B.3    Marasa, J.4    Milbrandt, J.5
  • 8
    • 84881495428 scopus 로고    scopus 로고
    • Sarm1-mediated axon degeneration requires both SAM and TIR interactions
    • Gerdts J, Summers DW, Sasaki Y, DiAntonio A, Milbrandt J. 2013. Sarm1-mediated axon degeneration requires both SAM and TIR interactions. Journal of Neuroscience 33:13569-13580. doi:10.1523/JNEUROSCI.1197-13.2013
    • (2013) Journal of Neuroscience , vol.33 , pp. 13569-13580
    • Gerdts, J.1    Summers, D.W.2    Sasaki, Y.3    Diantonio, A.4    Milbrandt, J.5
  • 9
    • 84928411460 scopus 로고    scopus 로고
    • SARM1 activation triggers axon degeneration locally via NAD+ destruction
    • Gerdts J, Brace EJ, Sasaki Y, DiAntonio A, Milbrandt J. 2015. SARM1 activation triggers axon degeneration locally via NAD+ destruction. Science 348:453-457. doi:10.1126/science.1258366
    • (2015) Science , vol.348 , pp. 453-457
    • Gerdts, J.1    Brace, E.J.2    Sasaki, Y.3    Diantonio, A.4    Milbrandt, J.5
  • 10
    • 84959314882 scopus 로고    scopus 로고
    • Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism
    • Gerdts J, Summers DW, Milbrandt J, DiAntonio A. 2016. Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism. Neuron 89:449-460. doi:10.1016/j.neuron.2015.12.023
    • (2016) Neuron , vol.89 , pp. 449-460
    • Gerdts, J.1    Summers, D.W.2    Milbrandt, J.3    Diantonio, A.4
  • 11
    • 77954617977 scopus 로고    scopus 로고
    • Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons
    • Gilley J, Coleman MP. 2010. Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. PLoS Biology 8:e1000300. doi:10.1371/journal.pbio.1000300
    • (2010) Plos Biology , vol.8
    • Gilley, J.1    Coleman, M.P.2
  • 12
    • 84925956889 scopus 로고    scopus 로고
    • Absence of SARM1 rescues development and survival of NMNAT2-deficient axons
    • Gilley J, Orsomando G, Nascimento-Ferreira I, Coleman MP. 2015. Absence of SARM1 rescues development and survival of NMNAT2-deficient axons. Cell Reports 10:1974-1981. doi:10.1016/j.celrep.2015.02.060
    • (2015) Cell Reports , vol.10 , pp. 1974-1981
    • Gilley, J.1    Orsomando, G.2    Nascimento-Ferreira, I.3    Coleman, M.P.4
  • 15
    • 0036468677 scopus 로고    scopus 로고
    • Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
    • Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. 2002. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science 295:868-872. doi:10.1126/science.1067081
    • (2002) Science , vol.295 , pp. 868-872
    • Lois, C.1    Hong, E.J.2    Pease, S.3    Brown, E.J.4    Baltimore, D.5
  • 18
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • Revollo JR, Grimm AA, Imai S. 2004. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. Journal of Biological Chemistry 279: 50754-50763. doi:10.1074/jbc.M408388200
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.3
  • 19
    • 33748174151 scopus 로고    scopus 로고
    • Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy
    • Sasaki Y, Araki T, Milbrandt J. 2006. Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy. Journal of Neuroscience 26:8484-8491. doi:10.1523/JNEUROSCI.2320-06.2006
    • (2006) Journal of Neuroscience , vol.26 , pp. 8484-8491
    • Sasaki, Y.1    Araki, T.2    Milbrandt, J.3
  • 20
    • 66249146403 scopus 로고    scopus 로고
    • Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo
    • Sasaki Y, Vohra BPS, Baloh RH, Milbrandt J. 2009a. Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo. Journal of Neuroscience 29:6526-6534. doi:10.1523/JNEUROSCI.1429-09.2009
    • (2009) Journal of Neuroscience , vol.29 , pp. 6526-6534
    • Sasaki, Y.1    Vohra, B.2    Baloh, R.H.3    Milbrandt, J.4
  • 21
    • 65649126738 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
    • Sasaki Y, Vohra BPS, Lund FE, Milbrandt J. 2009b. Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide. Journal of Neuroscience 29:5525-5535. doi:10.1523/JNEUROSCI.5469-08.2009
    • (2009) Journal of Neuroscience , vol.29 , pp. 5525-5535
    • Sasaki, Y.1    Vohra, B.2    Lund, F.E.3    Milbrandt, J.4
  • 22
    • 78650647681 scopus 로고    scopus 로고
    • Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons
    • Sasaki Y, Milbrandt J. 2010. Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons. Journal of Biological Chemistry 285: 41211-41215. doi:10.1074/jbc.C110.193904
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 41211-41215
    • Sasaki, Y.1    Milbrandt, J.2
  • 23
    • 69449098052 scopus 로고    scopus 로고
    • The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis
    • Szretter KJ, Samuel MA, Gilfillan S, Fuchs A, Colonna M, Diamond MS. 2009. The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis. Journal of Virology 83:9329-9338. doi:10.1128/JVI.00836-09
    • (2009) Journal of Virology , vol.83 , pp. 9329-9338
    • Szretter, K.J.1    Samuel, M.A.2    Gilfillan, S.3    Fuchs, A.4    Colonna, M.5    Diamond, M.S.6
  • 25
    • 84863012284 scopus 로고    scopus 로고
    • Axon degeneration: Molecular mechanisms of a self-destruction pathway
    • Wang JT, Medress ZA, Barres BA. 2012. Axon degeneration: molecular mechanisms of a self-destruction pathway. The Journal of Cell Biology 196:7-18. doi:10.1083/jcb.201108111
    • (2012) The Journal of Cell Biology , vol.196 , pp. 7-18
    • Wang, J.T.1    Medress, Z.A.2    Barres, B.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.