-
1
-
-
33751159209
-
Intracellular signaling by the unfolded protein response
-
Bernales S, Papa FR and Walter P (2006) Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol 22, 487–508.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 487-508
-
-
Bernales, S.1
Papa, F.R.2
Walter, P.3
-
2
-
-
0036853914
-
Orchestrating the unfolded protein response in health and disease
-
Kaufman RJ (2002) Orchestrating the unfolded protein response in health and disease. J Clin Invest 110, 1389–1398.
-
(2002)
J Clin Invest
, vol.110
, pp. 1389-1398
-
-
Kaufman, R.J.1
-
3
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D and Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8, 519–529.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
4
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M and Ron D (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 17, 5708–5717.
-
(1998)
EMBO J
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
5
-
-
0027324844
-
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
-
Cox JS, Shamu CE and Walter P (1993) Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73, 1197–1206.
-
(1993)
Cell
, vol.73
, pp. 1197-1206
-
-
Cox, J.S.1
Shamu, C.E.2
Walter, P.3
-
6
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon W, Welihinda AA and Kaufman RJ (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 12, 1812–1824.
-
(1998)
Genes Dev
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
7
-
-
0031941355
-
Unconventional splicing of HAC1/ERN4 mRNA required for the unfolded protein response – sequence-specific and non-sequential cleavage of the splice sites
-
Kawahara T, Yanagi H, Yura T and Mori K (1998) Unconventional splicing of HAC1/ERN4 mRNA required for the unfolded protein response – sequence-specific and non-sequential cleavage of the splice sites. J Biol Chem 273, 1802–1807.
-
(1998)
J Biol Chem
, vol.273
, pp. 1802-1807
-
-
Kawahara, T.1
Yanagi, H.2
Yura, T.3
Mori, K.4
-
8
-
-
0030954870
-
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
-
Sidrauski C and Walter P (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90, 1031–1039.
-
(1997)
Cell
, vol.90
, pp. 1031-1039
-
-
Sidrauski, C.1
Walter, P.2
-
9
-
-
0030808558
-
Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response
-
Kawahara T, Yanagi H, Yura T and Mori K (1997) Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response. Mol Biol Cell 8, 1845–1862.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1845-1862
-
-
Kawahara, T.1
Yanagi, H.2
Yura, T.3
Mori, K.4
-
10
-
-
0034712734
-
mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response
-
Mori K, Ogawa N, Kawahara T, Yanagi H and Yura T (2000) mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response. Proc Natl Acad Sci USA 97, 4660–4665.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4660-4665
-
-
Mori, K.1
Ogawa, N.2
Kawahara, T.3
Yanagi, H.4
Yura, T.5
-
11
-
-
0033152626
-
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway
-
Gonzalez TN, Sidrauski C, Dörfler S and Walter P (1999) Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J 18, 3119–3132.
-
(1999)
EMBO J
, vol.18
, pp. 3119-3132
-
-
Gonzalez, T.N.1
Sidrauski, C.2
Dörfler, S.3
Walter, P.4
-
12
-
-
18244405070
-
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
-
Shen X, Ellis RE, Lee K, Liu CY, Yang K, Solomon A, Yoshida H, Morimoto R, Kurnit DM, Mori K et al. (2001) Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development. Cell 107, 893–903.
-
(2001)
Cell
, vol.107
, pp. 893-903
-
-
Shen, X.1
Ellis, R.E.2
Lee, K.3
Liu, C.Y.4
Yang, K.5
Solomon, A.6
Yoshida, H.7
Morimoto, R.8
Kurnit, D.M.9
Mori, K.10
-
13
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T and Mori K (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881–891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
14
-
-
79960079763
-
Conserved RNA structures in the non-canonical Hac1/Xbp1 intron
-
Hooks KB and Griffiths-Jones S (2011) Conserved RNA structures in the non-canonical Hac1/Xbp1 intron. RNA Biol 8, 552–556.
-
(2011)
RNA Biol
, vol.8
, pp. 552-556
-
-
Hooks, K.B.1
Griffiths-Jones, S.2
-
15
-
-
0033598996
-
A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response
-
Niwa M, Sidrauski C, Kaufman RJ and Walter P (1999) A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Cell 99, 691–702.
-
(1999)
Cell
, vol.99
, pp. 691-702
-
-
Niwa, M.1
Sidrauski, C.2
Kaufman, R.J.3
Walter, P.4
-
16
-
-
0035964874
-
Differences in HAC1 mRNA processing and translation between yeast and mammalian cells indicate divergence of the eukaryotic ER stress response
-
Bowring CE and Llewellyn DH (2001) Differences in HAC1 mRNA processing and translation between yeast and mammalian cells indicate divergence of the eukaryotic ER stress response. Biochem Biophys Res Commun 287, 789–800.
-
(2001)
Biochem Biophys Res Commun
, vol.287
, pp. 789-800
-
-
Bowring, C.E.1
Llewellyn, D.H.2
-
17
-
-
77954175676
-
Domain compatibility in Ire1 kinase is critical for the unfolded protein response
-
Poothong J, Sopha P, Kaufman RJ and Tirasophon W (2010) Domain compatibility in Ire1 kinase is critical for the unfolded protein response. FEBS Lett 584, 3203–3208.
-
(2010)
FEBS Lett
, vol.584
, pp. 3203-3208
-
-
Poothong, J.1
Sopha, P.2
Kaufman, R.J.3
Tirasophon, W.4
-
18
-
-
33846829603
-
Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster
-
Plongthongkum N, Kullawong N, Panyim S and Tirasophon W (2007) Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster. Biochem Biophys Res Commun 354, 789–794.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 789-794
-
-
Plongthongkum, N.1
Kullawong, N.2
Panyim, S.3
Tirasophon, W.4
-
19
-
-
0347915684
-
High efficiency transformation by electroporation of Pichia pastoris pretreated with lithium acetate and dithiothreitol
-
Wu S and Letchworth GJ (2004) High efficiency transformation by electroporation of Pichia pastoris pretreated with lithium acetate and dithiothreitol. Biotechniques 36, 152–154.
-
(2004)
Biotechniques
, vol.36
, pp. 152-154
-
-
Wu, S.1
Letchworth, G.J.2
-
20
-
-
33644812855
-
Study of transcriptional regulation using a reporter gene assay
-
In, Xiao W, ed), Humana Press, Totowa, NJ
-
Fu Y and Xiao W (2006) Study of transcriptional regulation using a reporter gene assay. In Yeast Protocol (Xiao W, ed), pp. 257–264. Humana Press, Totowa, NJ.
-
(2006)
Yeast Protocol
, pp. 257-264
-
-
Fu, Y.1
Xiao, W.2
-
21
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K and Kaufman RJ (2002) IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16, 452–466.
-
(2002)
Genes Dev
, vol.16
, pp. 452-466
-
-
Lee, K.1
Tirasophon, W.2
Shen, X.3
Michalak, M.4
Prywes, R.5
Okada, T.6
Yoshida, H.7
Mori, K.8
Kaufman, R.J.9
-
22
-
-
0034637605
-
Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum
-
Liu CY, Schroder M and Kaufman RJ (2000) Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J Biol Chem 275, 24881–24885.
-
(2000)
J Biol Chem
, vol.275
, pp. 24881-24885
-
-
Liu, C.Y.1
Schroder, M.2
Kaufman, R.J.3
-
23
-
-
84918823958
-
The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells
-
Jurkin J, Henkel T, Nielsen AF, Minnich M, Popow J, Kaufmann T, Heindl K, Hoffmann T, Busslinger M and Martinez J (2014) The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO J 33, 2922–2936.
-
(2014)
EMBO J
, vol.33
, pp. 2922-2936
-
-
Jurkin, J.1
Henkel, T.2
Nielsen, A.F.3
Minnich, M.4
Popow, J.5
Kaufmann, T.6
Heindl, K.7
Hoffmann, T.8
Busslinger, M.9
Martinez, J.10
-
24
-
-
84926106643
-
A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB
-
Lu YY, Liang FX and Wang XZ (2014) A synthetic biology approach identifies the mammalian UPR RNA ligase RtcB. Mol Cell 55, 758–770.
-
(2014)
Mol Cell
, vol.55
, pp. 758-770
-
-
Lu, Y.Y.1
Liang, F.X.2
Wang, X.Z.3
-
25
-
-
79960272681
-
Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro
-
Shinya S, Kadokura H, Imagawa Y, Inoue M, Yanagitani K and Kohno K (2011) Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro. Nucleic Acids Res 39, 5245–5254.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 5245-5254
-
-
Shinya, S.1
Kadokura, H.2
Imagawa, Y.3
Inoue, M.4
Yanagitani, K.5
Kohno, K.6
-
26
-
-
0030297538
-
tRNA ligase is required for regulated mRNA splicing in the unfolded protein response
-
Sidrauski C, Cox JS and Walter P (1996) tRNA ligase is required for regulated mRNA splicing in the unfolded protein response. Cell 87, 405–413.
-
(1996)
Cell
, vol.87
, pp. 405-413
-
-
Sidrauski, C.1
Cox, J.S.2
Walter, P.3
-
27
-
-
0032698571
-
Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1
-
Foti DM, Welihinda A, Kaufman RJ and Lee AS (1999) Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1. J Biol Chem 274, 30402–30409.
-
(1999)
J Biol Chem
, vol.274
, pp. 30402-30409
-
-
Foti, D.M.1
Welihinda, A.2
Kaufman, R.J.3
Lee, A.S.4
-
28
-
-
84870159094
-
Structural basis of the unfolded protein response
-
Korennykh A and Walter P (2012) Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol 28, 251–277.
-
(2012)
Annu Rev Cell Dev Biol
, vol.28
, pp. 251-277
-
-
Korennykh, A.1
Walter, P.2
-
29
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J, Lin JH, Li H, Stevens N, Walter P and Weissman JS (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186, 323–331.
-
(2009)
J Cell Biol
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
30
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J and Weissman JS (2006) Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 104.
-
(2006)
Science
, vol.313
, pp. 104
-
-
Hollien, J.1
Weissman, J.S.2
-
31
-
-
68049110633
-
IRE1α kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D, Lerner AG, Walle LV, Upton J-P, Xu W, Hagen A, Backes BJ, Oakes SA and Papa FR (2009) IRE1α kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138, 562–575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Walle, L.V.3
Upton, J.-P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
32
-
-
77956016131
-
Identification of a consensus element recognized and cleaved by IRE1 alpha
-
Oikawa D, Tokuda M, Hosoda A and Iwawaki T (2010) Identification of a consensus element recognized and cleaved by IRE1 alpha. Nucleic Acids Res 38, 6265–6273.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 6265-6273
-
-
Oikawa, D.1
Tokuda, M.2
Hosoda, A.3
Iwawaki, T.4
-
34
-
-
84955445779
-
Protein misfolding in the endoplasmic reticulum as a conduit to human disease
-
Wang M and Kaufman RJ (2016) Protein misfolding in the endoplasmic reticulum as a conduit to human disease. Nature 529, 326–335.
-
(2016)
Nature
, vol.529
, pp. 326-335
-
-
Wang, M.1
Kaufman, R.J.2
|