Human exceptional longevity: Transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging

Aging

Volumn 8, Issue 12, 2016, Pages 3185-3208

  Borras, Consuelo ^a,b   Abdelaziz, Kheira M ^a,b   Gambini, Juan ^a,b   Serna, Eva ^a,b   Inglés, Marta ^c   de la Fuente, Monica ^d   Garcia, Idoia ^e,f   Matheu, Ander ^e,f   Sanchís, Paula ^g   Belenguer, Angel ^g   Errigo, Alessandra ^h   Avellana, Juan Antonio ^g   Barettino, Ana ⁱ   Lloret Fernández, Carla ⁱ   Flames, Nuria ⁱ   Pes, Gianni ^h   Rodriguez Mañas, Leocadio ^j   Viña, Jose ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Instituto Universitario IVI INCLIVA   (Spain)

^c UNIVERSITY OF VALENCIA   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^f BASQUE FOUNDATION FOR SCIENCE   (Spain)

^g HOSPITAL DE LA RIBERA   (Spain)

^h Dipartimento di Medicina Clinica e Sperimentale   (Italy)

ⁱ INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^j HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

more..

Author keywords

Apoptosis; Bcl 2; FAS ligand; Healthy aging; Longevity; RNA

Indexed keywords

BCL2L1 PROTEIN, HUMAN; MESSENGER RNA; PROTEIN BCL X; TRANSCRIPTOME;

AGED; ANIMAL; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LONGEVITY; METABOLISM; PHYSIOLOGY; UPREGULATION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANIMALS; BCL-X PROTEIN; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; HUMANS; LONGEVITY; RNA, MESSENGER; TRANSCRIPTOME; UP-REGULATION;

EID: 85010617301     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.101078     Document Type: Article

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