-
1
-
-
77958449984
-
α-Synuclein: membrane interactions and toxicity in Parkinson's disease
-
Auluck, P.K., Caraveo, G., Lindquist, S., α-Synuclein: membrane interactions and toxicity in Parkinson's disease. Annu. Rev. Cell Dev. Biol. 26 (2010), 211–233.
-
(2010)
Annu. Rev. Cell Dev. Biol.
, vol.26
, pp. 211-233
-
-
Auluck, P.K.1
Caraveo, G.2
Lindquist, S.3
-
2
-
-
77957347060
-
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro
-
Burré, J., Sharma, M., Tsetsenis, T., Buchman, V., Etherton, M.R., Südhof, T.C., Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science 329 (2010), 1663–1667.
-
(2010)
Science
, vol.329
, pp. 1663-1667
-
-
Burré, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.R.5
Südhof, T.C.6
-
3
-
-
84919449363
-
α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
-
Burré, J., Sharma, M., Südhof, T.C., α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation. Proc. Natl. Acad. Sci. USA 111 (2014), E4274–E4283.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E4274-E4283
-
-
Burré, J.1
Sharma, M.2
Südhof, T.C.3
-
4
-
-
84859702745
-
Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy
-
Cartier, A.E., Ubhi, K., Spencer, B., Vazquez-Roque, R.A., Kosberg, K.A., Fourgeaud, L., Kanayson, P., Patrick, C., Rockenstein, E., Patrick, G.N., Masliah, E., Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy. PLoS ONE, 7, 2012, e34713.
-
(2012)
PLoS ONE
, vol.7
, pp. e34713
-
-
Cartier, A.E.1
Ubhi, K.2
Spencer, B.3
Vazquez-Roque, R.A.4
Kosberg, K.A.5
Fourgeaud, L.6
Kanayson, P.7
Patrick, C.8
Rockenstein, E.9
Patrick, G.N.10
Masliah, E.11
-
5
-
-
27544507306
-
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
-
Chandra, S., Gallardo, G., Fernández-Chacón, R., Schlüter, O.M., Südhof, T.C., Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 123 (2005), 383–396.
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernández-Chacón, R.3
Schlüter, O.M.4
Südhof, T.C.5
-
6
-
-
0035903813
-
Co-association of parkin and alpha-synuclein
-
Choi, P., Golts, N., Snyder, H., Chong, M., Petrucelli, L., Hardy, J., Sparkman, D., Cochran, E., Lee, J.M., Wolozin, B., Co-association of parkin and alpha-synuclein. Neuroreport 12 (2001), 2839–2843.
-
(2001)
Neuroreport
, vol.12
, pp. 2839-2843
-
-
Choi, P.1
Golts, N.2
Snyder, H.3
Chong, M.4
Petrucelli, L.5
Hardy, J.6
Sparkman, D.7
Cochran, E.8
Lee, J.M.9
Wolozin, B.10
-
7
-
-
76049093950
-
Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression
-
Chung, C.Y., Koprich, J.B., Hallett, P.J., Isacson, O., Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression. Proc. Natl. Acad. Sci. USA 106 (2009), 22474–22479.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 22474-22479
-
-
Chung, C.Y.1
Koprich, J.B.2
Hallett, P.J.3
Isacson, O.4
-
8
-
-
84888070126
-
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons
-
Chung, C.Y., Khurana, V., Auluck, P.K., Tardiff, D.F., Mazzulli, J.R., Soldner, F., Baru, V., Lou, Y., Freyzon, Y., Cho, S., et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science 342 (2013), 983–987.
-
(2013)
Science
, vol.342
, pp. 983-987
-
-
Chung, C.Y.1
Khurana, V.2
Auluck, P.K.3
Tardiff, D.F.4
Mazzulli, J.R.5
Soldner, F.6
Baru, V.7
Lou, Y.8
Freyzon, Y.9
Cho, S.10
-
9
-
-
0032540327
-
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
-
Davidson, W.S., Jonas, A., Clayton, D.F., George, J.M., Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes. J. Biol. Chem. 273 (1998), 9443–9449.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
10
-
-
84860487766
-
A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism
-
Edvardson, S., Cinnamon, Y., Ta-Shma, A., Shaag, A., Yim, Y.I., Zenvirt, S., Jalas, C., Lesage, S., Brice, A., Taraboulos, A., et al. A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism. PLoS ONE, 7, 2012, e36458.
-
(2012)
PLoS ONE
, vol.7
, pp. e36458
-
-
Edvardson, S.1
Cinnamon, Y.2
Ta-Shma, A.3
Shaag, A.4
Yim, Y.I.5
Zenvirt, S.6
Jalas, C.7
Lesage, S.8
Brice, A.9
Taraboulos, A.10
-
11
-
-
84883521293
-
Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1
-
Ekholm-Reed, S., Goldberg, M.S., Schlossmacher, M.G., Reed, S.I., Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1. Mol. Cell. Biol. 33 (2013), 3627–3643.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 3627-3643
-
-
Ekholm-Reed, S.1
Goldberg, M.S.2
Schlossmacher, M.G.3
Reed, S.I.4
-
12
-
-
0032952414
-
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions
-
Engelender, S., Kaminsky, Z., Guo, X., Sharp, A.H., Amaravi, R.K., Kleiderlein, J.J., Margolis, R.L., Troncoso, J.C., Lanahan, A.A., Worley, P.F., et al. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat. Genet. 22 (1999), 110–114.
-
(1999)
Nat. Genet.
, vol.22
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Guo, X.3
Sharp, A.H.4
Amaravi, R.K.5
Kleiderlein, J.J.6
Margolis, R.L.7
Troncoso, J.C.8
Lanahan, A.A.9
Worley, P.F.10
-
13
-
-
38349160161
-
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis
-
Gitler, A.D., Bevis, B.J., Shorter, J., Strathearn, K.E., Hamamichi, S., Su, L.J., Caldwell, K.A., Caldwell, G.A., Rochet, J.C., McCaffery, J.M., et al. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proc. Natl. Acad. Sci. USA 105 (2008), 145–150.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 145-150
-
-
Gitler, A.D.1
Bevis, B.J.2
Shorter, J.3
Strathearn, K.E.4
Hamamichi, S.5
Su, L.J.6
Caldwell, K.A.7
Caldwell, G.A.8
Rochet, J.C.9
McCaffery, J.M.10
-
14
-
-
84871921766
-
100 years of Lewy pathology
-
Goedert, M., Spillantini, M.G., Del Tredici, K., Braak, H., 100 years of Lewy pathology. Nat. Rev. Neurol. 9 (2013), 13–24.
-
(2013)
Nat. Rev. Neurol.
, vol.9
, pp. 13-24
-
-
Goedert, M.1
Spillantini, M.G.2
Del Tredici, K.3
Braak, H.4
-
15
-
-
78650431984
-
αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction
-
Greten-Harrison, B., Polydoro, M., Morimoto-Tomita, M., Diao, L., Williams, A.M., Nie, E.H., Makani, S., Tian, N., Castillo, P.E., Buchman, V.L., Chandra, S.S., αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction. Proc. Natl. Acad. Sci. USA 107 (2010), 19573–19578.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 19573-19578
-
-
Greten-Harrison, B.1
Polydoro, M.2
Morimoto-Tomita, M.3
Diao, L.4
Williams, A.M.5
Nie, E.H.6
Makani, S.7
Tian, N.8
Castillo, P.E.9
Buchman, V.L.10
Chandra, S.S.11
-
16
-
-
84907772320
-
Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging
-
Hung, V., Zou, P., Rhee, H.W., Udeshi, N.D., Cracan, V., Svinkina, T., Carr, S.A., Mootha, V.K., Ting, A.Y., Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging. Mol. Cell 55 (2014), 332–341.
-
(2014)
Mol. Cell
, vol.55
, pp. 332-341
-
-
Hung, V.1
Zou, P.2
Rhee, H.W.3
Udeshi, N.D.4
Cracan, V.5
Svinkina, T.6
Carr, S.A.7
Mootha, V.K.8
Ting, A.Y.9
-
17
-
-
84924625546
-
Impaired intracellular trafficking defines early Parkinson's disease
-
Hunn, B.H.M., Cragg, S.J., Bolam, J.P., Spillantini, M.G., Wade-Martins, R., Impaired intracellular trafficking defines early Parkinson's disease. Trends Neurosci. 38 (2015), 178–188.
-
(2015)
Trends Neurosci.
, vol.38
, pp. 178-188
-
-
Hunn, B.H.M.1
Cragg, S.J.2
Bolam, J.P.3
Spillantini, M.G.4
Wade-Martins, R.5
-
18
-
-
84902142503
-
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy
-
Ivatt, R.M., Sanchez-Martinez, A., Godena, V.K., Brown, S., Ziviani, E., Whitworth, A.J., Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. Proc. Natl. Acad. Sci. USA 111 (2014), 8494–8499.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 8494-8499
-
-
Ivatt, R.M.1
Sanchez-Martinez, A.2
Godena, V.K.3
Brown, S.4
Ziviani, E.5
Whitworth, A.J.6
-
19
-
-
0033520474
-
alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356
-
Jensen, P.H., Hager, H., Nielsen, M.S., Hojrup, P., Gliemann, J., Jakes, R., alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356. J. Biol. Chem. 274 (1999), 25481–25489.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25481-25489
-
-
Jensen, P.H.1
Hager, H.2
Nielsen, M.S.3
Hojrup, P.4
Gliemann, J.5
Jakes, R.6
-
20
-
-
85010868689
-
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways
-
Khurana, V., Peng, J., Chung, C.Y., Auluck, P.K., Fanning, S., Tardiff, D.F., Bartels, T., Koeva, M., Eichhorn, S.W., Benyamini, H., et al. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Syst., 4, 2017, 10.1016/j.cels.2016.12.011.
-
(2017)
Cell Syst.
, vol.4
-
-
Khurana, V.1
Peng, J.2
Chung, C.Y.3
Auluck, P.K.4
Fanning, S.5
Tardiff, D.F.6
Bartels, T.7
Koeva, M.8
Eichhorn, S.W.9
Benyamini, H.10
-
21
-
-
84875605133
-
Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
-
Kim, H.J., Kim, N.C., Wang, Y.D., Scarborough, E.A., Moore, J., Diaz, Z., MacLea, K.S., Freibaum, B., Li, S., Molliex, A., et al. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature 495 (2013), 467–473.
-
(2013)
Nature
, vol.495
, pp. 467-473
-
-
Kim, H.J.1
Kim, N.C.2
Wang, Y.D.3
Scarborough, E.A.4
Moore, J.5
Diaz, Z.6
MacLea, K.S.7
Freibaum, B.8
Li, S.9
Molliex, A.10
-
22
-
-
33749583553
-
Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
-
Kontopoulos, E., Parvin, J.D., Feany, M.B., Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum. Mol. Genet. 15 (2006), 3012–3023.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 3012-3023
-
-
Kontopoulos, E.1
Parvin, J.D.2
Feany, M.B.3
-
23
-
-
84874271513
-
DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability
-
Köroğlu, Ç., Baysal, L., Cetinkaya, M., Karasoy, H., Tolun, A., DNAJC6 is responsible for juvenile parkinsonism with phenotypic variability. Parkinsonism Relat. Disord. 19 (2013), 320–324.
-
(2013)
Parkinsonism Relat. Disord.
, vol.19
, pp. 320-324
-
-
Köroğlu, Ç.1
Baysal, L.2
Cetinkaya, M.3
Karasoy, H.4
Tolun, A.5
-
24
-
-
84881610810
-
The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures
-
Krebs, C.E., Karkheiran, S., Powell, J.C., Cao, M., Makarov, V., Darvish, H., Di Paolo, G., Walker, R.H., Shahidi, G.A., Buxbaum, J.D., et al. The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures. Hum. Mutat. 34 (2013), 1200–1207.
-
(2013)
Hum. Mutat.
, vol.34
, pp. 1200-1207
-
-
Krebs, C.E.1
Karkheiran, S.2
Powell, J.C.3
Cao, M.4
Makarov, V.5
Darvish, H.6
Di Paolo, G.7
Walker, R.H.8
Shahidi, G.A.9
Buxbaum, J.D.10
-
25
-
-
84926166583
-
Directed evolution of APEX2 for electron microscopy and proximity labeling
-
Lam, S.S., Martell, J.D., Kamer, K.J., Deerinck, T.J., Ellisman, M.H., Mootha, V.K., Ting, A.Y., Directed evolution of APEX2 for electron microscopy and proximity labeling. Nat. Methods 12 (2015), 51–54.
-
(2015)
Nat. Methods
, vol.12
, pp. 51-54
-
-
Lam, S.S.1
Martell, J.D.2
Kamer, K.J.3
Deerinck, T.J.4
Ellisman, M.H.5
Mootha, V.K.6
Ting, A.Y.7
-
26
-
-
63849154465
-
Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease
-
Liu, Z., Meray, R.K., Grammatopoulos, T.N., Fredenburg, R.A., Cookson, M.R., Liu, Y., Logan, T., Lansbury, P.T. Jr., Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinson's disease. Proc. Natl. Acad. Sci. USA 106 (2009), 4635–4640.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4635-4640
-
-
Liu, Z.1
Meray, R.K.2
Grammatopoulos, T.N.3
Fredenburg, R.A.4
Cookson, M.R.5
Liu, Y.6
Logan, T.7
Lansbury, P.T.8
-
27
-
-
0023722437
-
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
-
Maroteaux, L., Campanelli, J.T., Scheller, R.H., Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J. Neurosci. 8 (1988), 2804–2815.
-
(1988)
J. Neurosci.
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
28
-
-
57049151865
-
Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions
-
McFarland, M.A., Ellis, C.E., Markey, S.P., Nussbaum, R.L., Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. Mol. Cell. Proteomics 7 (2008), 2123–2137.
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 2123-2137
-
-
McFarland, M.A.1
Ellis, C.E.2
Markey, S.P.3
Nussbaum, R.L.4
-
29
-
-
84865479029
-
Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation
-
Mizuno, N., Varkey, J., Kegulian, N.C., Hegde, B.G., Cheng, N., Langen, R., Steven, A.C., Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation. J. Biol. Chem. 287 (2012), 29301–29311.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 29301-29311
-
-
Mizuno, N.1
Varkey, J.2
Kegulian, N.C.3
Hegde, B.G.4
Cheng, N.5
Langen, R.6
Steven, A.C.7
-
30
-
-
84936777038
-
A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells
-
Müller-Kuller, U., Ackermann, M., Kolodziej, S., Brendel, C., Fritsch, J., Lachmann, N., Kunkel, H., Lausen, J., Schambach, A., Moritz, T., Grez, M., A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res. 43 (2015), 1577–1592.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 1577-1592
-
-
Müller-Kuller, U.1
Ackermann, M.2
Kolodziej, S.3
Brendel, C.4
Fritsch, J.5
Lachmann, N.6
Kunkel, H.7
Lausen, J.8
Schambach, A.9
Moritz, T.10
Grez, M.11
-
31
-
-
34248205797
-
Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage
-
Nakai, M., Fujita, M., Waragai, M., Sugama, S., Wei, J., Akatsu, H., Ohtaka-Maruyama, C., Okado, H., Hashimoto, M., Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage. Biochem. Biophys. Res. Commun. 358 (2007), 104–110.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.358
, pp. 104-110
-
-
Nakai, M.1
Fujita, M.2
Waragai, M.3
Sugama, S.4
Wei, J.5
Akatsu, H.6
Ohtaka-Maruyama, C.7
Okado, H.8
Hashimoto, M.9
-
32
-
-
84939599004
-
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
-
Nalls, M.A., Pankratz, N., Lill, C.M., Do, C.B., Hernandez, D.G., Saad, M., DeStefano, A.L., Kara, E., Bras, J., Sharma, M., et al. International Parkinson's Disease Genomics Consortium (IPDGC) Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI) 23andMe GenePD NeuroGenetics Research Consortium (NGRC) Hussman Institute of Human Genomics (HIHG) Ashkenazi Jewish Dataset Investigator Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE) North American Brain Expression Consortium (NABEC) United Kingdom Brain Expression Consortium (UKBEC) Greek Parkinson's Disease Consortium, Alzheimer Genetic Analysis Group. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat. Genet. 46 (2014), 989–993.
-
(2014)
Nat. Genet.
, vol.46
, pp. 989-993
-
-
Nalls, M.A.1
Pankratz, N.2
Lill, C.M.3
Do, C.B.4
Hernandez, D.G.5
Saad, M.6
DeStefano, A.L.7
Kara, E.8
Bras, J.9
Sharma, M.10
-
33
-
-
84904559734
-
PARK20 caused by SYNJ1 homozygous Arg258Gln mutation in a new Italian family
-
Olgiati, S., De Rosa, A., Quadri, M., Criscuolo, C., Breedveld, G.J., Picillo, M., Pappatà, S., Quarantelli, M., Barone, P., De Michele, G., Bonifati, V., PARK20 caused by SYNJ1 homozygous Arg258Gln mutation in a new Italian family. Neurogenetics 15 (2014), 183–188.
-
(2014)
Neurogenetics
, vol.15
, pp. 183-188
-
-
Olgiati, S.1
De Rosa, A.2
Quadri, M.3
Criscuolo, C.4
Breedveld, G.J.5
Picillo, M.6
Pappatà, S.7
Quarantelli, M.8
Barone, P.9
De Michele, G.10
Bonifati, V.11
-
34
-
-
84958133702
-
DNAJC6 mutations associated with early-onset Parkinson's disease
-
Olgiati, S., et al. DNAJC6 mutations associated with early-onset Parkinson's disease. Ann. Neurol., 2015.
-
(2015)
Ann. Neurol.
-
-
Olgiati, S.1
-
35
-
-
84881612311
-
Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism
-
Quadri, M., Fang, M., Picillo, M., Olgiati, S., Breedveld, G.J., Graafland, J., Wu, B., Xu, F., Erro, R., Amboni, M., et al., International Parkinsonism Genetics Network. Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism. Hum. Mutat. 34 (2013), 1208–1215.
-
(2013)
Hum. Mutat.
, vol.34
, pp. 1208-1215
-
-
Quadri, M.1
Fang, M.2
Picillo, M.3
Olgiati, S.4
Breedveld, G.J.5
Graafland, J.6
Wu, B.7
Xu, F.8
Erro, R.9
Amboni, M.10
-
36
-
-
84874956967
-
Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging
-
Rhee, H.W., Zou, P., Udeshi, N.D., Martell, J.D., Mootha, V.K., Carr, S.A., Ting, A.Y., Proteomic mapping of mitochondria in living cells via spatially restricted enzymatic tagging. Science 339 (2013), 1328–1331.
-
(2013)
Science
, vol.339
, pp. 1328-1331
-
-
Rhee, H.W.1
Zou, P.2
Udeshi, N.D.3
Martell, J.D.4
Mootha, V.K.5
Carr, S.A.6
Ting, A.Y.7
-
37
-
-
77953796839
-
A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration
-
Scott, D.A., Tabarean, I., Tang, Y., Cartier, A., Masliah, E., Roy, S., A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. J. Neurosci. 30 (2010), 8083–8095.
-
(2010)
J. Neurosci.
, vol.30
, pp. 8083-8095
-
-
Scott, D.A.1
Tabarean, I.2
Tang, Y.3
Cartier, A.4
Masliah, E.5
Roy, S.6
-
38
-
-
84857059950
-
CSPα knockout causes neurodegeneration by impairing SNAP-25 function
-
Sharma, M., Burré, J., Bronk, P., Zhang, Y., Xu, W., Südhof, T.C., CSPα knockout causes neurodegeneration by impairing SNAP-25 function. EMBO J. 31 (2012), 829–841.
-
(2012)
EMBO J.
, vol.31
, pp. 829-841
-
-
Sharma, M.1
Burré, J.2
Bronk, P.3
Zhang, Y.4
Xu, W.5
Südhof, T.C.6
-
39
-
-
79960149653
-
Parkinson's Disease: Genetics and Pathogenesis
-
Shulman, J.M., De Jager, P.L., Feany, M.B., Parkinson's Disease: Genetics and Pathogenesis. Annu. Rev. Pathol., 2010.
-
(2010)
Annu. Rev. Pathol.
-
-
Shulman, J.M.1
De Jager, P.L.2
Feany, M.B.3
-
40
-
-
0032574840
-
A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo
-
Stagljar, I., Korostensky, C., Johnsson, N., te Heesen, S., A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. Proc. Natl. Acad. Sci. USA 95 (1998), 5187–5192.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5187-5192
-
-
Stagljar, I.1
Korostensky, C.2
Johnsson, N.3
te Heesen, S.4
-
41
-
-
84940029424
-
Multisystem proteinopathy: intersecting genetics in muscle, bone, and brain degeneration
-
Taylor, J.P., Multisystem proteinopathy: intersecting genetics in muscle, bone, and brain degeneration. Neurology 85 (2015), 658–660.
-
(2015)
Neurology
, vol.85
, pp. 658-660
-
-
Taylor, J.P.1
-
42
-
-
84885012783
-
Large-scale identification of ubiquitination sites by mass spectrometry
-
Udeshi, N.D., Mertins, P., Svinkina, T., Carr, S.A., Large-scale identification of ubiquitination sites by mass spectrometry. Nat. Protoc. 8 (2013), 1950–1960.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 1950-1960
-
-
Udeshi, N.D.1
Mertins, P.2
Svinkina, T.3
Carr, S.A.4
-
43
-
-
84904006504
-
Synucleins regulate the kinetics of synaptic vesicle endocytosis
-
Vargas, K.J., Makani, S., Davis, T., Westphal, C.H., Castillo, P.E., Chandra, S.S., Synucleins regulate the kinetics of synaptic vesicle endocytosis. J. Neurosci. 34 (2014), 9364–9376.
-
(2014)
J. Neurosci.
, vol.34
, pp. 9364-9376
-
-
Vargas, K.J.1
Makani, S.2
Davis, T.3
Westphal, C.H.4
Castillo, P.E.5
Chandra, S.S.6
-
44
-
-
58549119203
-
Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease
-
Yasuda, T., Nihira, T., Ren, Y.R., Cao, X.Q., Wada, K., Setsuie, R., Kabuta, T., Wada, K., Hattori, N., Mizuno, Y., Mochizuki, H., Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease. J. Neurochem. 108 (2009), 932–944.
-
(2009)
J. Neurochem.
, vol.108
, pp. 932-944
-
-
Yasuda, T.1
Nihira, T.2
Ren, Y.R.3
Cao, X.Q.4
Wada, K.5
Setsuie, R.6
Kabuta, T.7
Wada, K.8
Hattori, N.9
Mizuno, Y.10
Mochizuki, H.11
-
45
-
-
80051534540
-
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease
-
Zimprich, A., Benet-Pagès, A., Struhal, W., Graf, E., Eck, S.H., Offman, M.N., Haubenberger, D., Spielberger, S., Schulte, E.C., Lichtner, P., et al. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am. J. Hum. Genet. 89 (2011), 168–175.
-
(2011)
Am. J. Hum. Genet.
, vol.89
, pp. 168-175
-
-
Zimprich, A.1
Benet-Pagès, A.2
Struhal, W.3
Graf, E.4
Eck, S.H.5
Offman, M.N.6
Haubenberger, D.7
Spielberger, S.8
Schulte, E.C.9
Lichtner, P.10
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