메뉴 건너뛰기




Volumn 34, Issue 28, 2014, Pages 9364-9376

Synucleins regulate the kinetics of synaptic vesicle endocytosis

Author keywords

AP180; Endocytosis; Membrane bending; Parkinson's disease; Presynaptic; Synaptobrevin

Indexed keywords

ALPHA SYNUCLEIN; BETA SYNUCLEIN; GAMMA SYNUCLEIN; SYNUCLEIN;

EID: 84904006504     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4787-13.2014     Document Type: Article
Times cited : (229)

References (67)
  • 2
    • 38049180885 scopus 로고    scopus 로고
    • Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode
    • CrossRef Medline
    • Balaji J., Ryan TA (2007) Single-vesicle imaging reveals that synaptic vesicle exocytosis and endocytosis are coupled by a single stochastic mode. Proc Natl Acad Sci U S A 104:20576-20581. CrossRef Medline
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 20576-20581
    • Balaji, J.1    Ryan, T.A.2
  • 3
    • 58549089901 scopus 로고    scopus 로고
    • Alpha-synuclein and polyunsaturated fatty acids promote clathrinmediated endocytosis and synaptic vesicle recycling
    • CrossRef Medline
    • Ben Gedalya T., Loeb V, Israeli E, Altschuler Y, Selkoe DJ, Sharon R (2009) Alpha-synuclein and polyunsaturated fatty acids promote clathrinmediated endocytosis and synaptic vesicle recycling. Traffic 10:218-234. CrossRef Medline
    • (2009) Traffic , vol.10 , pp. 218-234
    • Ben Gedalya, T.1    Loeb, V.2    Israeli, E.3    Altschuler, Y.4    Selkoe, D.J.5    Sharon, R.6
  • 4
    • 84884250340 scopus 로고    scopus 로고
    • The function of alpha-synuclein
    • CrossRef Medline
    • Bendor J. T, Logan TP, Edwards RH (2013) The function of alpha-synuclein. Neuron 79:1044-1066. CrossRef Medline
    • (2013) Neuron , vol.79 , pp. 1044-1066
    • Bendor, J.T.1    Logan, T.P.2    Edwards, R.H.3
  • 6
    • 77957347060 scopus 로고    scopus 로고
    • Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro
    • CrossRef Medline
    • Burré J., Sharma M, Tsetsenis T, Buchman V, Etherton MR, Südhof TC (2010) Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science 329:1663-1667. CrossRef Medline
    • (2010) Science , vol.329 , pp. 1663-1667
    • Burré, J.1    Sharma, M.2    Tsetsenis, T.3    Buchman, V.4    Etherton, M.R.5    Südhof, T.C.6
  • 7
    • 84867787595 scopus 로고    scopus 로고
    • Systematic mutagenesis of alphasynuclein reveals distinct sequence requirements for physiological and pathological activities
    • CrossRef Medline
    • Burré J., Sharma M, Südhof TC (2012) Systematic mutagenesis of alphasynuclein reveals distinct sequence requirements for physiological and pathological activities. J Neurosci 32:15227-15242. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 15227-15242
    • Burré, J.1    Sharma, M.2    Südhof, T.C.3
  • 9
    • 84876511972 scopus 로고    scopus 로고
    • Synucleins
    • In: (Squire L, ed.), New York: Oxford Academic
    • Chandra S. (2009) Synucleins. In: The new encyclopedia of neuroscience, Vol. 9 (Squire L, ed.), pp 833-837. New York: Oxford Academic.
    • (2009) The new encyclopedia of neuroscience , vol.9 , pp. 833-837
    • Chandra, S.1
  • 10
    • 0038341134 scopus 로고    scopus 로고
    • A broken alpha-helix in folded alpha-Synuclein
    • CrossRef Medline
    • Chandra S., Chen X, Rizo J, Jahn R, Südhof TC (2003) A broken alpha-helix in folded alpha-Synuclein. J Biol Chem 278:15313-15318. CrossRef Medline
    • (2003) J Biol Chem , vol.278 , pp. 15313-15318
    • Chandra, S.1    Chen, X.2    Rizo, J.3    Jahn, R.4    Südhof, T.C.5
  • 12
    • 27544507306 scopus 로고    scopus 로고
    • Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
    • CrossRef Medline
    • Chandra S., Gallardo G, Fernández-Chacón R, Schlüter OM, Südhof TC (2005) Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell 123:383-396. CrossRef Medline
    • (2005) Cell , vol.123 , pp. 383-396
    • Chandra, S.1    Gallardo, G.2    Fernández-Chacón, R.3    Schlüter, O.M.4    Südhof, T.C.5
  • 13
    • 80054823535 scopus 로고    scopus 로고
    • alpha-Synuclein promotes clathrin-mediated NMDA receptor endocytosis and attenuates NMDA-induced dopaminergic cell death
    • CrossRef Medline
    • Cheng F., Li X, Li Y, Wang C, Wang T, Liu G, Baskys A, Uéda K, Chan P, Yu S (2011) alpha-Synuclein promotes clathrin-mediated NMDA receptor endocytosis and attenuates NMDA-induced dopaminergic cell death. J Neurochem 119:815-825. CrossRef Medline
    • (2011) J Neurochem , vol.119 , pp. 815-825
    • Cheng, F.1    Li, X.2    Li, Y.3    Wang, C.4    Wang, T.5    Liu, G.6    Baskys, A.7    Uéda, K.8    Chan, P.9    Yu, S.10
  • 15
    • 0033215063 scopus 로고    scopus 로고
    • Synucleins in synaptic plasticity and neurodegenerative disorders
    • CrossRef Medline
    • Clayton D. F, George JM (1999) Synucleins in synaptic plasticity and neurodegenerative disorders. J Neurosci Res 58:120-129. CrossRef Medline
    • (1999) J Neurosci Res , vol.58 , pp. 120-129
    • Clayton, D.F.1    George, J.M.2
  • 18
    • 77954215793 scopus 로고    scopus 로고
    • Alpha-synuclein sequesters arachidonic acid to modulate SNAREmediated exocytosis
    • CrossRef Medline
    • Darios F., Ruipérez V, López I, Villanueva J, Gutierrez LM, Davletov B (2010) Alpha-synuclein sequesters arachidonic acid to modulate SNAREmediated exocytosis. EMBO Rep 11:528-533. CrossRef Medline
    • (2010) EMBO Rep , vol.11 , pp. 528-533
    • Darios, F.1    Ruipérez, V.2    López, I.3    Villanueva, J.4    Gutierrez, L.M.5    Davletov, B.6
  • 19
    • 7944229497 scopus 로고    scopus 로고
    • Synaptobrevin is essential for fast synaptic-vesicle endocytosis
    • CrossRef Medline
    • Deák F., Schoch S, Liu X, Südhof TC, Kavalali ET (2004) Synaptobrevin is essential for fast synaptic-vesicle endocytosis. Nat Cell Biol 6:1102-1108. CrossRef Medline
    • (2004) Nat Cell Biol , vol.6 , pp. 1102-1108
    • Deák, F.1    Schoch, S.2    Liu, X.3    Südhof, T.C.4    Kavalali, E.T.5
  • 20
    • 80055082804 scopus 로고    scopus 로고
    • Parkinson's disease and alpha-synuclein expression
    • CrossRef Medline
    • Devine M. J, Gwinn K, Singleton A, Hardy J (2011) Parkinson's disease and alpha-synuclein expression. Mov Disord 26:2160-2168. CrossRef Medline
    • (2011) Mov Disord , vol.26 , pp. 2160-2168
    • Devine, M.J.1    Gwinn, K.2    Singleton, A.3    Hardy, J.4
  • 21
    • 84875990438 scopus 로고    scopus 로고
    • alpha-Synuclein Can Inhibit SNAREMediated Vesicle Fusion through Direct Interactions with Lipid Bilayers
    • CrossRef Medline
    • DeWitt D. C, Rhoades E (2013) alpha-Synuclein Can Inhibit SNAREMediated Vesicle Fusion through Direct Interactions with Lipid Bilayers. Biochemistry 52:2385-2387. CrossRef Medline
    • (2013) Biochemistry , vol.52 , pp. 2385-2387
    • DeWitt, D.C.1    Rhoades, E.2
  • 22
    • 84879033702 scopus 로고    scopus 로고
    • Native α-synuclein induces clustering of synapticvesicle mimics via binding to phospholipids and synaptobrevin-2/ VAMP2
    • CrossRef Medline
    • Diao J., Burré J, Vivona S, Cipriano DJ, Sharma M, Kyoung M, Südhof TC, Brunger A. T (2013) Native α-synuclein induces clustering of synapticvesicle mimics via binding to phospholipids and synaptobrevin-2/ VAMP2. Elife 2:e00592. CrossRef Medline
    • (2013) Elife , vol.2
    • Diao, J.1    Burré, J.2    Vivona, S.3    Cipriano, D.J.4    Sharma, M.5    Kyoung, M.6    Südhof, T.C.7    Brunger, A.T.8
  • 24
    • 70350218812 scopus 로고    scopus 로고
    • Molecular circuitry of endocytosis at nerve terminals
    • CrossRef Medline
    • Dittman J., Ryan TA (2009) Molecular circuitry of endocytosis at nerve terminals. Annu Rev Cell Dev Biol 25:133-160. CrossRef Medline
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 133-160
    • Dittman, J.1    Ryan, T.A.2
  • 27
    • 65249185574 scopus 로고    scopus 로고
    • Interplay of alphasynuclein binding and conformational switching probed by singlemolecule fluorescence
    • CrossRef Medline
    • Ferreon A. C, Gambin Y, Lemke EA, Deniz AA (2009) Interplay of alphasynuclein binding and conformational switching probed by singlemolecule fluorescence. Proc Natl Acad Sci U S A 106:5645-5650. CrossRef Medline
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5645-5650
    • Ferreon, A.C.1    Gambin, Y.2    Lemke, E.A.3    Deniz, A.A.4
  • 28
    • 33748576937 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses
    • CrossRef Medline
    • Granseth B., Odermatt B, Royle SJ, Lagnado L (2006) Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron 51:773-786. CrossRef Medline
    • (2006) Neuron , vol.51 , pp. 773-786
    • Granseth, B.1    Odermatt, B.2    Royle, S.J.3    Lagnado, L.4
  • 30
    • 84865864065 scopus 로고    scopus 로고
    • The genetics and neuropathology of Parkinson's disease
    • CrossRef Medline
    • Houlden H., Singleton AB (2012) The genetics and neuropathology of Parkinson's disease. Acta Neuropathol 124:325-338. CrossRef Medline
    • (2012) Acta Neuropathol , vol.124 , pp. 325-338
    • Houlden, H.1    Singleton, A.B.2
  • 31
    • 0020955120 scopus 로고
    • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • CrossRef Medline
    • Huttner W. B, Schiebler W, Greengard P, De Camilli P (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 96:1374-1388. CrossRef Medline
    • (1983) J Cell Biol , vol.96 , pp. 1374-1388
    • Huttner, W.B.1    Schiebler, W.2    Greengard, P.3    De Camilli, P.4
  • 32
    • 2942555022 scopus 로고    scopus 로고
    • Structure of membranebound alpha-synuclein studied by site-directed spin labeling
    • CrossRef Medline
    • Jao C. C, Der-Sarkissian A, Chen J, Langen R (2004) Structure of membranebound alpha-synuclein studied by site-directed spin labeling. Proc Natl Acad Sci U S A 101:8331-8336. CrossRef Medline
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8331-8336
    • Jao, C.C.1    Der-Sarkissian, A.2    Chen, J.3    Langen, R.4
  • 33
    • 82755176258 scopus 로고    scopus 로고
    • Membrane curvature sensing by amphipathic helices: A single liposome study using alpha-synuclein and annexin B12
    • CrossRef Medline
    • Jensen M. B, Bhatia VK, Jao CC, Rasmussen JE, Pedersen SL, Jensen KJ, Langen R, Stamou D (2011) Membrane curvature sensing by amphipathic helices: a single liposome study using alpha-synuclein and annexin B12. J Biol Chem 286:42603-42614. CrossRef Medline
    • (2011) J Biol Chem , vol.286 , pp. 42603-42614
    • Jensen, M.B.1    Bhatia, V.K.2    Jao, C.C.3    Rasmussen, J.E.4    Pedersen, S.L.5    Jensen, K.J.6    Langen, R.7    Stamou, D.8
  • 34
    • 34249704608 scopus 로고    scopus 로고
    • Identification of novel proteins associated with both alpha-synuclein and DJ-1
    • CrossRef Medline
    • Jin J., Li GJ, Davis J, Zhu D, Wang Y, Pan C, Zhang J (2007) Identification of novel proteins associated with both alpha-synuclein and DJ-1. Mol Cell Proteomics 6:845-859. CrossRef Medline
    • (2007) Mol Cell Proteomics , vol.6 , pp. 845-859
    • Jin, J.1    Li, G.J.2    Davis, J.3    Zhu, D.4    Wang, Y.5    Pan, C.6    Zhang, J.7
  • 35
    • 84894252017 scopus 로고    scopus 로고
    • The clathrin-dependent localization of dopamine transporter to surface membranes is affected by alphasynuclein
    • CrossRef Medline
    • Kisos H., Ben-Gedalya T, Sharon R (2014) The clathrin-dependent localization of dopamine transporter to surface membranes is affected by alphasynuclein. J Mol Neurosci 52:167-176. CrossRef Medline
    • (2014) J Mol Neurosci , vol.52 , pp. 167-176
    • Kisos, H.1    Ben-Gedalya, T.2    Sharon, R.3
  • 38
    • 52949083619 scopus 로고    scopus 로고
    • A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans
    • CrossRef Medline
    • Kuwahara T., Koyama A, Koyama S, Yoshina S, Ren CH, Kato T, Mitani S, Iwatsubo T. (2008) A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans. Hum Mol Genet 17:2997-3009. CrossRef Medline
    • (2008) Hum Mol Genet , vol.17 , pp. 2997-3009
    • Kuwahara, T.1    Koyama, A.2    Koyama, S.3    Yoshina, S.4    Ren, C.H.5    Kato, T.6    Mitani, S.7    Iwatsubo, T.8
  • 39
    • 79958033258 scopus 로고    scopus 로고
    • Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons
    • CrossRef Medline
    • Kwon S. E, Chapman ER (2011) Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70:847-854. CrossRef Medline
    • (2011) Neuron , vol.70 , pp. 847-854
    • Kwon, S.E.1    Chapman, E.R.2
  • 41
    • 0037067993 scopus 로고    scopus 로고
    • Differential localization of alpha-, beta-and gamma-synucleins in the rat CNS
    • CrossRef Medline
    • Li J., Henning Jensen P, Dahlström A (2002) Differential localization of alpha-, beta-and gamma-synucleins in the rat CNS. Neuroscience 113: 463-478. CrossRef Medline
    • (2002) Neuroscience , vol.113 , pp. 463-478
    • Li, J.1    Henning Jensen, P.2    Dahlström, A.3
  • 43
    • 37049034663 scopus 로고    scopus 로고
    • The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals
    • CrossRef Medline
    • Mani M., Lee SY, Lucast L, Cremona O, Di Paolo G, De Camilli P, Ryan TA (2007) The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals. Neuron 56:1004-1018. CrossRef Medline
    • (2007) Neuron , vol.56 , pp. 1004-1018
    • Mani, M.1    Lee, S.Y.2    Lucast, L.3    Cremona, O.4    Di Paolo, G.5    De Camilli, P.6    Ryan, T.A.7
  • 45
    • 0026727853 scopus 로고
    • Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling
    • CrossRef Medline
    • Maycox P. R, Link E, Reetz A, Morris SA, Jahn R (1992) Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling. J Cell Biol 118:1379-1388. CrossRef Medline
    • (1992) J Cell Biol , vol.118 , pp. 1379-1388
    • Maycox, P.R.1    Link, E.2    Reetz, A.3    Morris, S.A.4    Jahn, R.5
  • 47
    • 84865479029 scopus 로고    scopus 로고
    • Remodeling of lipid vesicles into cylindrical micelles by alphasynuclein in an extended alpha-helical conformation
    • CrossRef Medline
    • Mizuno N., Varkey J, Kegulian NC, Hegde BG, Cheng N, Langen R, Steven AC (2012) Remodeling of lipid vesicles into cylindrical micelles by alphasynuclein in an extended alpha-helical conformation. J Biol Chem 287: 29301-29311. CrossRef Medline
    • (2012) J Biol Chem , vol.287 , pp. 29301-29311
    • Mizuno, N.1    Varkey, J.2    Kegulian, N.C.3    Hegde, B.G.4    Cheng, N.5    Langen, R.6    Steven, A.C.7
  • 49
    • 0035928748 scopus 로고    scopus 로고
    • Membrane binding and self-association of alpha-synucleins
    • CrossRef Medline
    • Narayanan V., Scarlata S (2001) Membrane binding and self-association of alpha-synucleins. Biochemistry 40:9927-9934. CrossRef Medline
    • (2001) Biochemistry , vol.40 , pp. 9927-9934
    • Narayanan, V.1    Scarlata, S.2
  • 50
    • 73549085595 scopus 로고    scopus 로고
    • Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis
    • CrossRef Medline
    • Nemani V. M, Lu W, Berge V, Nakamura K, Onoa B, Lee MK, Chaudhry FA, Nicoll R. A, Edwards RH (2010) Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis. Neuron 65:66-79. CrossRef Medline
    • (2010) Neuron , vol.65 , pp. 66-79
    • Nemani, V.M.1    Lu, W.2    Berge, V.3    Nakamura, K.4    Onoa, B.5    Lee, M.K.6    Chaudhry, F.A.7    Nicoll, R.A.8    Edwards, R.H.9
  • 51
    • 84871745200 scopus 로고    scopus 로고
    • Contrasting effects of alpha-synuclein and gammasynuclein on the phenotype of cysteine string protein alpha (CSPalpha) null mutant mice suggest distinct function of these proteins in neuronal synapses
    • CrossRef Medline
    • Ninkina N., Peters OM, Connor-Robson N, Lytkina O, Sharfeddin E, Buchman VL (2012) Contrasting effects of alpha-synuclein and gammasynuclein on the phenotype of cysteine string protein alpha (CSPalpha) null mutant mice suggest distinct function of these proteins in neuronal synapses. J Biol Chem 287:44471-44477. CrossRef Medline
    • (2012) J Biol Chem , vol.287 , pp. 44471-44477
    • Ninkina, N.1    Peters, O.M.2    Connor-Robson, N.3    Lytkina, O.4    Sharfeddin, E.5    Buchman, V.L.6
  • 52
    • 0035500991 scopus 로고    scopus 로고
    • Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells
    • CrossRef Medline
    • Payton J. E, Perrin RJ, Clayton DF, George JM (2001) Protein-protein interactions of alpha-synuclein in brain homogenates and transfected cells. Brain Res Mol Brain Res 95:138-145. CrossRef Medline
    • (2001) Brain Res Mol Brain Res , vol.95 , pp. 138-145
    • Payton, J.E.1    Perrin, R.J.2    Clayton, D.F.3    George, J.M.4
  • 53
    • 79960279832 scopus 로고    scopus 로고
    • alpha-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding
    • CrossRef Medline
    • Pranke I. M, Morello V, Bigay J, Gibson K, Verbavatz JM, Antonny B, Jackson CL (2011) alpha-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding. J Cell Biol 194:89-103. CrossRef Medline
    • (2011) J Cell Biol , vol.194 , pp. 89-103
    • Pranke, I.M.1    Morello, V.2    Bigay, J.3    Gibson, K.4    Verbavatz, J.M.5    Antonny, B.6    Jackson, C.L.7
  • 57
    • 84864258151 scopus 로고    scopus 로고
    • alpha-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis
    • CrossRef Medline
    • Scott D., Roy S (2012) alpha-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis. J Neurosci 32:10129-10135. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 10129-10135
    • Scott, D.1    Roy, S.2
  • 58
    • 78650505099 scopus 로고    scopus 로고
    • CSPalpha promotes SNAREcomplex assembly by chaperoning SNAP-25 during synaptic activity
    • CrossRef Medline
    • Sharma M., Burré J, Südhof TC (2011) CSPalpha promotes SNAREcomplex assembly by chaperoning SNAP-25 during synaptic activity. Nat Cell Biol 13:30-39. CrossRef Medline
    • (2011) Nat Cell Biol , vol.13 , pp. 30-39
    • Sharma, M.1    Burré, J.2    Südhof, T.C.3
  • 60
    • 2942556680 scopus 로고    scopus 로고
    • The synaptic vesicle cycle
    • CrossRef Medline
    • Sudhof T. C (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27:509-547. CrossRef Medline
    • (2004) Annu Rev Neurosci , vol.27 , pp. 509-547
    • Sudhof, T.C.1
  • 61
    • 72149095496 scopus 로고    scopus 로고
    • SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination
    • CrossRef Medline
    • Trempe J. F, Chen CX, Grenier K, Camacho EM, Kozlov G, McPherson PS, Gehring K., Fon EA (2009) SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination. Mol Cell 36:1034-1047. CrossRef Medline
    • (2009) Mol Cell , vol.36 , pp. 1034-1047
    • Trempe, J.F.1    Chen, C.X.2    Grenier, K.3    Camacho, E.M.4    Kozlov, G.5    McPherson, P.S.6    Gehring, K.7    Fon, E.A.8
  • 64
    • 84872744821 scopus 로고    scopus 로고
    • Monomeric synucleins generate membrane curvature
    • CrossRef Medline
    • Westphal C. H, Chandra SS (2013) Monomeric synucleins generate membrane curvature. J Biol Chem 288:1829-1840. CrossRef Medline
    • (2013) J Biol Chem , vol.288 , pp. 1829-1840
    • Westphal, C.H.1    Chandra, S.S.2
  • 65
    • 36348950454 scopus 로고    scopus 로고
    • Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy
    • CrossRef Medline
    • Woods W. S, Boettcher JM, Zhou DH, Kloepper KD, Hartman KL, Ladror DT, Qi Z., Rienstra CM, George JM (2007) Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy. J Biol Chem 282:34555-34567. CrossRef Medline
    • (2007) J Biol Chem , vol.282 , pp. 34555-34567
    • Woods, W.S.1    Boettcher, J.M.2    Zhou, D.H.3    Kloepper, K.D.4    Hartman, K.L.5    Ladror, D.T.6    Qi, Z.7    Rienstra, C.M.8    George, J.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.