Differential roles of AXIN1 and AXIN2 in tankyrase inhibitor-induced formation of degradasomes and β-catenin degradation

PLoS ONE

Volumn 12, Issue 1, 2017, Pages

  Thorvaldsen, Tor Espen ^a   Pedersen, Nina Marie ^a   Wenzel, Eva Maria ^a   Stenmark, Harald ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AXIN; AXIN1; AXIN2; BETA CATENIN; G 007LK; UNCLASSIFIED DRUG; AXIN1 PROTEIN, HUMAN; AXIN2 PROTEIN, HUMAN; G007-LK; PROTEASOME; SULFONE; TANKYRASE; TRIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COLORECTAL CANCER CELL LINE; COMPLEX FORMATION; CONTROLLED STUDY; DEGRADASOME; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; UPREGULATION; WNT SIGNALING PATHWAY; ANTAGONISTS AND INHIBITORS; COLORECTAL TUMOR; CYTOPLASM VESICLE; HUMAN; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE; WESTERN BLOTTING; WNT SIGNALING;

AXIN PROTEIN; BETA CATENIN; BLOTTING, WESTERN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYTOPLASMIC VESICLES; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SULFONES; TANKYRASES; TRIAZOLES; WNT SIGNALING PATHWAY;

EID: 85010297395     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0170508     Document Type: Article

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