Gold-quercetin nanoparticles prevent metabolic endotoxemia-induced kidney injury by regulating TLR4/NF-kB signaling and Nrf2 pathway in high fat diet fed mice

International Journal of Nanomedicine

Volumn 12, Issue , 2017, Pages 327-345

  Xu, Min Xuan ^a,b   Wang, Ming ^c   Yang, Wei Wei ^d  

^a CHONGQING UNIVERSITY OF EDUCATION   (China)

^b NANJING UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gold quercetin nanoparticles; Kidney injury; Nrf2; Podocytes; TLR4 NF B

Indexed keywords

ENDOTOXIN; GOLD NANOPARTICLE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; POLYGLACTIN; QUERCETIN; SUPEROXIDE DISMUTASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR NRF2; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE; GOLD; LIPOPOLYSACCHARIDE; NANOPARTICLE; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD EXAMINATION; C57BL 6 MOUSE; CELL DAMAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG MECHANISM; ENDOTOXEMIA; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IN VITRO STUDY; INFLAMMATION; INSULIN RESISTANCE; KIDNEY FAILURE; KIDNEY INJURY; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PODOCYTE; RENAL PROTECTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BLOOD; C57BL MOUSE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; KIDNEY; LIVER; METABOLISM; PATHOLOGY; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT;

ANIMALS; CELL SURVIVAL; DIET, HIGH-FAT; ENDOTOXEMIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; GOLD; INFLAMMATION; KIDNEY; LIPOPOLYSACCHARIDES; LIVER; MALE; MICE, INBRED C57BL; NANOPARTICLES; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PLATELET AGGREGATION; PLATELET COUNT; PODOCYTES; QUERCETIN; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TOLL-LIKE RECEPTOR 4;

EID: 85010030252     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S116010     Document Type: Article

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