-
1
-
-
77955984085
-
The role of innate immunity in septic acute kidney injuries
-
Goncalves, Zamboni, and Camara The role of innate immunity in septic acute kidney injuries Shock 34 Suppl. 1 2010 22 26
-
(2010)
Shock
, vol.34
, pp. 22-26
-
-
Goncalves1
Zamboni2
Camara3
-
2
-
-
77949351028
-
Acute kidney injury associates with increased long-term mortality
-
Lafrance, and Miller Acute kidney injury associates with increased long-term mortality J. Am. Soc. Nephrol. 21 2010 345 352
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 345-352
-
-
Lafrance1
Miller2
-
4
-
-
34548229961
-
Septic acute kidney injury in critically ill patients: Clinical characteristics and outcomes
-
Bagshaw, Uchino, Bellomo, Morimatsu, Morgera, Schetz, and et al. Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes Clin. J. Am. Soc. Nephrol. 2 2007 431 439
-
(2007)
Clin. J. Am. Soc. Nephrol.
, vol.2
, pp. 431-439
-
-
Bagshaw1
Uchino2
Bellomo3
Morimatsu4
Morgera5
Schetz6
-
5
-
-
33747802067
-
Pharmacological properties of the ubiquitous natural product betulin
-
Alakurtti, Makela, Koskimies, and Yli-Kauhaluoma Pharmacological properties of the ubiquitous natural product betulin Eur. J. Pharm. Sci. 29 2006 1 13
-
(2006)
Eur. J. Pharm. Sci.
, vol.29
, pp. 1-13
-
-
Alakurtti1
Makela2
Koskimies3
Yli-Kauhaluoma4
-
6
-
-
0037049876
-
Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells
-
Zuco, Supino, Righetti, Cleris, Marchesi, Gambacorti-Passerini, and et al. Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells Cancer Lett. 175 2002 17 25
-
(2002)
Cancer Lett.
, vol.175
, pp. 17-25
-
-
Zuco1
Supino2
Righetti3
Cleris4
Marchesi5
Gambacorti-Passerini6
-
7
-
-
41649102467
-
Pathophysiology of septic acute kidney injury: What do we really know?
-
Wan, Bagshaw, Langenberg, Saotome, May, and Bellomo Pathophysiology of septic acute kidney injury: what do we really know? Crit. Care Med. 36 2008 S198 S203
-
(2008)
Crit. Care Med.
, vol.36
, pp. S198-S203
-
-
Wan1
Bagshaw2
Langenberg3
Saotome4
May5
Bellomo6
-
8
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss, and Karl The pathophysiology and treatment of sepsis N. Engl. J. Med. 348 2003 138 150
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 138-150
-
-
Hotchkiss1
Karl2
-
9
-
-
84973434090
-
Dexmedetomidine protects against acute kidney injury through downregulating inflammatory reactions in endotoxemia rats
-
Tan, Chen, Yuan, Gong, Li, and Zhou Dexmedetomidine protects against acute kidney injury through downregulating inflammatory reactions in endotoxemia rats Biomed. Rep. 3 2015 365 370
-
(2015)
Biomed. Rep.
, vol.3
, pp. 365-370
-
-
Tan1
Chen2
Yuan3
Gong4
Li5
Zhou6
-
10
-
-
84935854517
-
MiR-15a/16 are upreuglated in the serum of neonatal sepsis patients and inhibit the LPS-induced inflammatory pathway
-
Wang, Wang, Liu, Wang, Xu, Hou, and et al. miR-15a/16 are upreuglated in the serum of neonatal sepsis patients and inhibit the LPS-induced inflammatory pathway Int. J. Clin. Exp. Med. 8 2015 5683 5690
-
(2015)
Int. J. Clin. Exp. Med.
, vol.8
, pp. 5683-5690
-
-
Wang1
Wang2
Liu3
Wang4
Xu5
Hou6
-
11
-
-
84938630574
-
Decoy receptor 3 improves survival in experimental sepsis by suppressing the inflammatory response and lymphocyte apoptosis
-
Liang, Hou, Lou, and Chen Decoy receptor 3 improves survival in experimental sepsis by suppressing the inflammatory response and lymphocyte apoptosis PLoS One 10 2015 e0131680
-
(2015)
PLoS One
, vol.10
-
-
Liang1
Hou2
Lou3
Chen4
-
12
-
-
84935505553
-
Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-kappaB pathway
-
Zhang, Jiao, Li, and Wang Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-kappaB pathway Mol. Med. Rep. 2015
-
(2015)
Mol. Med. Rep.
-
-
Zhang1
Jiao2
Li3
Wang4
-
13
-
-
84895864300
-
Pleiotropic effects of Blastocystis spp. Subtypes 4 and 7 on ligand-specific toll-like receptor signaling and NF-kappaB activation in a human monocyte cell line
-
Teo, Macary, and Tan Pleiotropic effects of Blastocystis spp. Subtypes 4 and 7 on ligand-specific toll-like receptor signaling and NF-kappaB activation in a human monocyte cell line PLoS One 9 2014 e89036
-
(2014)
PLoS One
, vol.9
-
-
Teo1
MacAry2
Tan3
-
14
-
-
84928102563
-
Continuous hemodiafiltration therapy reduces damage of multi-organs by ameliorating of HMGB1/TLR4/NFkappaB in a dog sepsis model
-
Sun, Shi, Wang, Yu, Wang Continuous hemodiafiltration therapy reduces damage of multi-organs by ameliorating of HMGB1/TLR4/NFkappaB in a dog sepsis model Int. J. Clin. Exp. Pathol. 8 2015 1555 1564
-
(2015)
Int. J. Clin. Exp. Pathol.
, vol.8
, pp. 1555-1564
-
-
Sun1
Shi2
Wang3
Yu4
Wang5
-
15
-
-
84877272838
-
Dexmedetomidine inhibits inflammatory reaction in lung tissues of septic rats by suppressing TLR4/NF-kappaB pathway
-
Wu, Liu, Huang, Zhu, Zhang, Lu, and et al. Dexmedetomidine inhibits inflammatory reaction in lung tissues of septic rats by suppressing TLR4/NF-kappaB pathway Mediators. Inflamm. 2013 2013 562154
-
(2013)
Mediators. Inflamm.
, vol.2013
, pp. 562154
-
-
Wu1
Liu2
Huang3
Zhu4
Zhang5
Lu6
-
16
-
-
84855379544
-
Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction
-
Rodrigues, Sanches, Volpini, Shimizu, Kuriki, Camara, and et al. Effects of continuous erythropoietin receptor activator in sepsis-induced acute kidney injury and multi-organ dysfunction PLoS One 7 2012 e29893
-
(2012)
PLoS One
, vol.7
-
-
Sanches1
Volpini2
Shimizu3
Kuriki4
Camara5
-
17
-
-
84941066671
-
Betulin inhibits pro-inflammatory cytokines expression through activation STAT3 signaling pathway in human cardiac cells
-
Zhang, Zhao, Fang, Yu Betulin inhibits pro-inflammatory cytokines expression through activation STAT3 signaling pathway in human cardiac cells Eur. Rev. Med. Pharmacol. Sci. 19 2015 455 460
-
(2015)
Eur. Rev. Med. Pharmacol. Sci.
, vol.19
, pp. 455-460
-
-
Zhang1
Zhao2
Fang3
Yu4
-
18
-
-
84908692664
-
Betulin protects mice from bacterial pneumonia and acute lung injury
-
Wu, Li, Qiu, Feng Betulin protects mice from bacterial pneumonia and acute lung injury Microb. Pathog. 75 2014 21 28
-
(2014)
Microb. Pathog.
, vol.75
, pp. 21-28
-
-
Wu1
Li2
Qiu3
Feng4
-
19
-
-
0142249406
-
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice
-
Miyaji, Hu, Yuen, Muramatsu, Iyer, Hewitt, and et al. Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice Kidney Int. 64 2003 1620 1631
-
(2003)
Kidney Int.
, vol.64
, pp. 1620-1631
-
-
Miyaji1
Hu2
Yuen3
Muramatsu4
Iyer5
Hewitt6
-
20
-
-
0018964280
-
Sepsis and septic shock - A review of laboratory models and a proposal
-
Wichterman, Baue, Chaudry Sepsis and septic shock - a review of laboratory models and a proposal J. Surg. Res. 29 1980 189 201
-
(1980)
J. Surg. Res.
, vol.29
, pp. 189-201
-
-
Wichterman1
Baue2
Chaudry3
-
21
-
-
79953292076
-
Cecal ligation and puncture: The gold standard model for polymicrobial sepsis?
-
Dejager, Pinheiro, Dejonckheere, Libert Cecal ligation and puncture: the gold standard model for polymicrobial sepsis? Trends Microbiol. 19 2011 198 208
-
(2011)
Trends Microbiol.
, vol.19
, pp. 198-208
-
-
Dejager1
Pinheiro2
Dejonckheere3
-
22
-
-
84961288986
-
Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis
-
Lingaraju, Pathak, Begum, Balaganur, Ramachandra, Bhat, and et al. Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis Eur. J. Pharm. Sci. 70 2015 12 21
-
(2015)
Eur. J. Pharm. Sci.
, vol.70
, pp. 12-21
-
-
Lingaraju1
Pathak2
Begum3
Balaganur4
Ramachandra5
Bhat6
-
23
-
-
0029944101
-
Christman Sepsis and cytokines: Current status
-
Blackwell, Christman Sepsis and cytokines: current status Br. J. Anaesth. 77 1996 110 117
-
(1996)
Br. J. Anaesth.
, vol.77
, pp. 110-117
-
-
Blackwell1
-
24
-
-
0036738495
-
Cancer therapy and renal injury
-
Schrier Cancer therapy and renal injury J. Clin. Invest. 110 2002 743 745
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 743-745
-
-
Schrier1
-
25
-
-
0036604216
-
Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney
-
Cunningham, Dyanov, Park, Wang, Newell, Quigg Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney J. Immunol. 168 2002 5817 5823
-
(2002)
J. Immunol.
, vol.168
, pp. 5817-5823
-
-
Cunningham1
Dyanov2
Park3
Wang4
Newell5
-
26
-
-
0029835023
-
Carlet INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group
-
Cohen, Carlet INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group Crit. Care Med. 24 1996 1431 1440
-
(1996)
Crit. Care Med.
, vol.24
, pp. 1431-1440
-
-
Cohen1
-
27
-
-
77954382754
-
The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1beta production, ROS production and endosomal rupture
-
Morishige, Yoshioka, Inakura, Tanabe, Yao, Narimatsu, and et al. The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1beta production, ROS production and endosomal rupture Biomaterials 31 2010 6833 6842
-
(2010)
Biomaterials
, vol.31
, pp. 6833-6842
-
-
Orishige1
Yoshioka2
Inakura3
Tanabe4
Yao5
Narimatsu6
-
28
-
-
48049096638
-
IL-6/IL-6R axis plays a critical role in acute kidney injury
-
Nechemia-Arbely, Barkan, Pizov, Shriki, Rose-John, Galun, and et al. IL-6/IL-6R axis plays a critical role in acute kidney injury J. Am. Soc. Nephrol. 19 2008 1106 1115
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 1106-1115
-
-
Barkan1
Pizov2
Shriki3
Rose-John4
Galun5
-
29
-
-
34548259894
-
Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis
-
Chawla, Seneff, Nelson, Williams, Levy, Kimmel, and et al. Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis Clin. J. Am. Soc. Nephrol. 2 2007 22 30
-
(2007)
Clin. J. Am. Soc. Nephrol.
, vol.2
, pp. 22-30
-
-
Seneff1
Nelson2
Williams3
Levy4
Kimmel5
-
30
-
-
0015857760
-
A new group of chromatin-associated proteins with a high content of acidic and basic amino acids
-
Goodwin, Sanders, Johns A new group of chromatin-associated proteins with a high content of acidic and basic amino acids Eur. J. Biochem. 38 1973 14 19
-
(1973)
Eur. J. Biochem.
, vol.38
, pp. 14-19
-
-
Goodwin1
Sanders2
Johns3
-
31
-
-
0033538467
-
HMG-1 as a late mediator of endotoxin lethality in mice
-
Wang, Bloom, Zhang, Vishnubhakat, Ombrellino, Che, and et al. HMG-1 as a late mediator of endotoxin lethality in mice Science 285 1999 248 251
-
(1999)
Science
, vol.285
, pp. 248-251
-
-
Bloom1
Zhang2
Vishnubhakat3
Ombrellino4
Che5
-
32
-
-
48149096398
-
HMGB1: Endogenous danger signaling
-
Klune, Dhupar, Cardinal, Billiar, Tsung HMGB1: endogenous danger signaling Mol. Med. 14 2008 476 484
-
(2008)
Mol. Med.
, vol.14
, pp. 476-484
-
-
Klune1
Dhupar2
Cardinal3
Billiar4
Tsung5
-
33
-
-
79961120130
-
HMGB1 as an autophagy sensor in oxidative stress
-
Kang, Livesey, Zeh, Lotze, Tang HMGB1 as an autophagy sensor in oxidative stress Autophagy 7 2011 904 906
-
(2011)
Autophagy
, vol.7
, pp. 904-906
-
-
Kang1
Livesey2
Zeh3
Lotze4
Tang5
-
34
-
-
0141830087
-
IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism
-
Rendon-Mitchell, Ochani, Li, Han, Wang, Yang, and et al. IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism J. Immunol. 170 2003 3890 3897
-
(2003)
J. Immunol.
, vol.170
, pp. 3890-3897
-
-
Ochani1
Li2
Han3
Wang4
Yang5
-
35
-
-
33845867117
-
HMGB1-secreting capacity of multiple cell lineages revealed by a novel HMGB1 ELISPOT assay
-
Wahamaa, Vallerskog, Qin, Lunderius, LaRosa, Andersson, and et al. HMGB1-secreting capacity of multiple cell lineages revealed by a novel HMGB1 ELISPOT assay J. Leukoc. Biol. 81 2007 129 136
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 129-136
-
-
Vallerskog1
Qin2
Lunderius3
LaRosa4
Andersson5
-
36
-
-
79952366675
-
High-mobility group box 1, oxidative stress, and disease
-
Tang, Kang, Zeh, Lotze High-mobility group box 1, oxidative stress, and disease Antioxid. Redox Signal 14 2011 1315 1335
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 1315-1335
-
-
Tang1
Kang2
Zeh3
Lotze4
-
37
-
-
33646578794
-
Sepsis induces changes in the expression and distribution of Toll-like receptor 4 in the rat kidney
-
El-Achkar, Huang, Plotkin, Sandoval, Rhodes, Dagher Sepsis induces changes in the expression and distribution of Toll-like receptor 4 in the rat kidney Am. J. Physiol. Renal Physiol. 290 2006 F1034 F1043
-
(2006)
Am. J. Physiol. Renal Physiol.
, vol.290
, pp. F1034-F1043
-
-
El-Achkar1
Huang2
Plotkin3
Sandoval4
Rhodes5
Dagher6
-
38
-
-
84940399401
-
Therapeutic effects of treatment with anti-TLR2 and anti-TLR4 monoclonal antibodies in polymicrobial sepsis
-
Lima, Souza, Amaral, Fagundes, Rodrigues, Alves-Filho, and et al. Therapeutic effects of treatment with anti-TLR2 and anti-TLR4 monoclonal antibodies in polymicrobial sepsis PLoS One 10 2015 e0132336
-
(2015)
PLoS One
, vol.10
-
-
Souza1
Amaral2
Fagundes3
Rodrigues4
Alves-Filho5
-
39
-
-
33645116785
-
NF-kappa B activation as a pathological mechanism of septic shock and inflammation
-
Liu, Malik NF-kappa B activation as a pathological mechanism of septic shock and inflammation Am. J. Physiol. Lung. Cell. Mol. Physiol. 290 2006 L622 L645
-
(2006)
Am. J. Physiol. Lung. Cell. Mol. Physiol.
, vol.290
, pp. L622-L645
-
-
Malik, L.1
-
40
-
-
0030611086
-
Role of NFkappaB in the mortality of sepsis
-
Bohrer, Qiu, Zimmermann, Zhang, Jllmer, Mannel, and et al. Role of NFkappaB in the mortality of sepsis J. Clin. Invest. 100 1997 972 985
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 972-985
-
-
Qiu1
Zimmermann2
Zhang3
Jllmer4
Mannel5
-
41
-
-
0036275030
-
Inhibition of nuclear factor-kappaB activation by IRFI 042, protects against endotoxin-induced shock
-
Altavilla, Squadrito, Minutoli, Deodato, Bova, Sardella, and et al. Inhibition of nuclear factor-kappaB activation by IRFI 042, protects against endotoxin-induced shock Cardiovasc. Res. 54 2002 684 693
-
(2002)
Cardiovasc. Res.
, vol.54
, pp. 684-693
-
-
Squadrito1
Minutoli2
Deodato3
Bova4
Sardella5
-
42
-
-
33750860428
-
Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin
-
Shames, Meldrum, Selzman, Pulido, Cain, Banerjee, and et al. Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin Am. J. Physiol. 275 1998 H1084 H1091
-
(1998)
Am. J. Physiol.
, vol.275
, pp. H1084-H1091
-
-
Meldrum1
Selzman2
Pulido3
Cain4
Banerjee5
-
43
-
-
1542380035
-
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
-
Park, Svetkauskaite, He, Kim, Strassheim, Ishizaka, and et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein J. Biol. Chem. 279 2004 7370 7377
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7370-7377
-
-
Park1
Svetkauskaite2
He3
Kim4
Strassheim5
Ishizaka6
-
44
-
-
33645461206
-
High mobility group box 1 protein interacts with multiple Toll-like receptors
-
Park, Gamboni-Robertson, He, Svetkauskaite, Kim, Strassheim, and et al. High mobility group box 1 protein interacts with multiple Toll-like receptors Am. J. Physiol. Cell. Physiol. 290 2006 C917 C924
-
(2006)
Am. J. Physiol. Cell. Physiol.
, vol.290
, pp. C917-C924
-
-
Gamboni-Robertson1
He2
Svetkauskaite3
Kim4
Strassheim5
-
45
-
-
33847193122
-
A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin
-
Orlova, Choi, Xie, Chavakis, Bierhaus, Ihanus, and et al. A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin EMBO J. 26 2007 1129 1139
-
(2007)
EMBO J.
, vol.26
, pp. 1129-1139
-
-
Choi1
Xie2
Chavakis3
Bierhaus4
Ihanus5
|