메뉴 건너뛰기




Volumn 9, Issue 1, 2016, Pages

Elucidation of the roles of adhE1 and adhE2 in the primary metabolism of Clostridium acetobutylicum by combining in-frame gene deletion and a quantitative system-scale approach

Author keywords

AdhE; Butanol; Clostridium acetobutylicum; System scale analysis

Indexed keywords


EID: 85009954120     PISSN: 17546834     EISSN: None     Source Type: Journal    
DOI: 10.1186/s13068-016-0507-0     Document Type: Article
Times cited : (38)

References (39)
  • 1
    • 0027957210 scopus 로고
    • Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824
    • Nair RV, Bennett GN, Papoutsakis ET. Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824. J Bacteriol. 1994;176(3):871-85.
    • (1994) J Bacteriol. , vol.176 , Issue.3 , pp. 871-885
    • Nair, R.V.1    Bennett, G.N.2    Papoutsakis, E.T.3
  • 2
    • 80052625837 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicum: Recent advances to improve butanol production
    • Lutke-Eversloh T, Bahl H. Metabolic engineering of Clostridium acetobutylicum: recent advances to improve butanol production. Curr Opin Biotechnol. 2011;22(5):634-47.
    • (2011) Curr Opin Biotechnol. , vol.22 , Issue.5 , pp. 634-647
    • Lutke-Eversloh, T.1    Bahl, H.2
  • 3
    • 53049083876 scopus 로고    scopus 로고
    • Metabolic engineering for advanced biofuels production from Escherichia coli
    • Atsumi S, Liao JC. Metabolic engineering for advanced biofuels production from Escherichia coli. Curr Opin Biotechnol. 2008;19(5):414-9.
    • (2008) Curr Opin Biotechnol. , vol.19 , Issue.5 , pp. 414-419
    • Atsumi, S.1    Liao, J.C.2
  • 4
    • 0028201690 scopus 로고
    • Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol
    • Vasconcelos I, Girbal L, Soucaille P. Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol. J Bacteriol. 1994;176(5):1443-50.
    • (1994) J Bacteriol. , vol.176 , Issue.5 , pp. 1443-1450
    • Vasconcelos, I.1    Girbal, L.2    Soucaille, P.3
  • 5
    • 0028907367 scopus 로고
    • How neutral red modified carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH
    • Girbal L, Vasconcelos I, Saint-Amans S, Soucaille P. How neutral red modified carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH. FEMS Microbiol Rev. 1995;16(2):151-62.
    • (1995) FEMS Microbiol Rev. , vol.16 , Issue.2 , pp. 151-162
    • Girbal, L.1    Vasconcelos, I.2    Saint-Amans, S.3    Soucaille, P.4
  • 6
    • 0028036995 scopus 로고
    • Regulation of Clostridium acetobutylicum metabolism as revealed by mixed-substrate steady-state continuous cultures: Role of NADH/NAD ratio and ATP pool
    • Girbal L, Soucaille P. Regulation of Clostridium acetobutylicum metabolism as revealed by mixed-substrate steady-state continuous cultures: role of NADH/NAD ratio and ATP pool. J Bacteriol. 1994;176(21):6433-8.
    • (1994) J Bacteriol. , vol.176 , Issue.21 , pp. 6433-6438
    • Girbal, L.1    Soucaille, P.2
  • 7
    • 0031885009 scopus 로고    scopus 로고
    • Regulation of solvent production in Clostridium acetobutylicum
    • Girbal L, Soucaille P. Regulation of solvent production in Clostridium acetobutylicum. Trends Biotechnol. 1998;16(1):11-6.
    • (1998) Trends Biotechnol. , vol.16 , Issue.1 , pp. 11-16
    • Girbal, L.1    Soucaille, P.2
  • 8
    • 0020358856 scopus 로고
    • Continuous production of acetone and butanol by Clostridium acetobutylicum in a two-stage phosphate limited chemostat
    • Bahl H, Andersch W, Gottschalk G. Continuous production of acetone and butanol by Clostridium acetobutylicum in a two-stage phosphate limited chemostat. Eur J Appl Microbiol Biotechnol. 1982;15(4):201-5.
    • (1982) Eur J Appl Microbiol Biotechnol. , vol.15 , Issue.4 , pp. 201-205
    • Bahl, H.1    Andersch, W.2    Gottschalk, G.3
  • 9
    • 78650924319 scopus 로고    scopus 로고
    • Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis in continuous cultures of Clostridium acetobutylicum
    • Grimmler C, Janssen H, Krauße D, Fischer R-J, Bahl H, Dürre P, Liebl W, Ehrenreich A. Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis in continuous cultures of Clostridium acetobutylicum. J Mol Microbiol Biotechnol. 2011;20(1):1-15.
    • (2011) J Mol Microbiol Biotechnol. , vol.20 , Issue.1 , pp. 1-15
    • Grimmler, C.1    Janssen, H.2    Krauße, D.3    Fischer, R.-J.4    Bahl, H.5    Dürre, P.6    Liebl, W.7    Ehrenreich, A.8
  • 10
    • 0028893691 scopus 로고
    • Modulation of Carbon and Electron Flow in Clostridium acetobutylicum by Iron Limitation and Methyl Viologen Addition
    • Peguin S, Soucaille P. Modulation of Carbon and Electron Flow in Clostridium acetobutylicum by Iron Limitation and Methyl Viologen Addition. Appl Environ Microbiol. 1995;61(1):403-5.
    • (1995) Appl Environ Microbiol. , vol.61 , Issue.1 , pp. 403-405
    • Peguin, S.1    Soucaille, P.2
  • 11
    • 0027383357 scopus 로고
    • Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis
    • Fischer RJ, Helms J, Durre P. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis. J Bacteriol. 1993;175(21):6959-69.
    • (1993) J Bacteriol. , vol.175 , Issue.21 , pp. 6959-6969
    • Fischer, R.J.1    Helms, J.2    Durre, P.3
  • 12
    • 84952802569 scopus 로고    scopus 로고
    • A Quantitative System-Scale Characterization of the Metabolism of Clostridium acetobutylicum
    • Yoo M, Bestel-Corre G, Croux C, Riviere A, Meynial-Salles I, Soucaille P. A Quantitative System-Scale Characterization of the Metabolism of Clostridium acetobutylicum. MBio 2015, 6(6):e01808-01815.
    • (2015) MBio , vol.6 , Issue.6 , pp. e01808-01815
    • Yoo, M.1    Bestel-Corre, G.2    Croux, C.3    Riviere, A.4    Meynial-Salles, I.5    Soucaille, P.6
  • 13
    • 0028830955 scopus 로고
    • Differential induction of genes related to solvent formation during the shift from acidogenesis to solventogenesis in continuous culture of Clostridium acetobutylicum
    • Sauer U, Dürre P. Differential induction of genes related to solvent formation during the shift from acidogenesis to solventogenesis in continuous culture of Clostridium acetobutylicum. FEMS Microbiol Lett. 1995;125(1):115-20.
    • (1995) FEMS Microbiol Lett. , vol.125 , Issue.1 , pp. 115-120
    • Sauer, U.1    Dürre, P.2
  • 14
    • 0036180998 scopus 로고    scopus 로고
    • Molecular characterization and transcriptional analysis of adhE2, the gene encoding the NADH-dependent aldehyde/alcohol dehydrogenase responsible for butanol production in alcohologenic cultures of Clostridium acetobutylicum ATCC 824
    • Fontaine L, Meynial-Salles I, Girbal L, Yang X, Croux C, Soucaille P. Molecular characterization and transcriptional analysis of adhE2, the gene encoding the NADH-dependent aldehyde/alcohol dehydrogenase responsible for butanol production in alcohologenic cultures of Clostridium acetobutylicum ATCC 824. J Bacteriol. 2002;184(3):821-30.
    • (2002) J Bacteriol. , vol.184 , Issue.3 , pp. 821-830
    • Fontaine, L.1    Meynial-Salles, I.2    Girbal, L.3    Yang, X.4    Croux, C.5    Soucaille, P.6
  • 15
    • 84874738185 scopus 로고    scopus 로고
    • A genetic system for Clostridium ljungdahlii: A chassis for autotrophic production of biocommodities and a model homoacetogen
    • Leang C, Ueki T, Nevin KP, Lovley DR. A genetic system for Clostridium ljungdahlii: a chassis for autotrophic production of biocommodities and a model homoacetogen. Appl Environ Microbiol. 2013;79(4):1102-9.
    • (2013) Appl Environ Microbiol. , vol.79 , Issue.4 , pp. 1102-1109
    • Leang, C.1    Ueki, T.2    Nevin, K.P.3    Lovley, D.R.4
  • 16
    • 84869014233 scopus 로고    scopus 로고
    • Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway
    • Cooksley CM, Zhang Y, Wang H, Redl S, Winzer K, Minton NP. Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway. Metab Eng. 2012;14(6):630-41.
    • (2012) Metab Eng. , vol.14 , Issue.6 , pp. 630-641
    • Cooksley, C.M.1    Zhang, Y.2    Wang, H.3    Redl, S.4    Winzer, K.5    Minton, N.P.6
  • 18
    • 85026903165 scopus 로고    scopus 로고
    • Salmonella marker vaccine
    • Apfel H. Salmonella marker vaccine. In.: Google Patents; 2012.
    • (2012) Google Patents
    • Apfel, H.1
  • 19
    • 0037652305 scopus 로고    scopus 로고
    • Specific targeted integration of kanamycin resistance-associated nonselectable DNA in the genome of the yeast Saccharomyces cerevisiae
    • 1033
    • Waghmare SK, Caputo V, Radovic S, Bruschi CV. Specific targeted integration of kanamycin resistance-associated nonselectable DNA in the genome of the yeast Saccharomyces cerevisiae. Biotechniques 2003, 34(5):1024-1028, 1033.
    • (2003) Biotechniques , vol.34 , Issue.5 , pp. 1024-1028
    • Waghmare, S.K.1    Caputo, V.2    Radovic, S.3    Bruschi, C.V.4
  • 20
    • 0033833940 scopus 로고    scopus 로고
    • Involvement of the inverted repeat of the yeast 2-micron plasmid in Flp site-specific and RAD52-dependent homologous recombination
    • Storici F, Bruschi CV. Involvement of the inverted repeat of the yeast 2-micron plasmid in Flp site-specific and RAD52-dependent homologous recombination. Mol Gen Genet. 2000;263(1):81-9.
    • (2000) Mol Gen Genet. , vol.263 , Issue.1 , pp. 81-89
    • Storici, F.1    Bruschi, C.V.2
  • 21
    • 0028791403 scopus 로고
    • Regulation of metabolic shifts in Clostridium acetobutylicum ATCC 824
    • Girbal L, Croux C, Vasconcelos I, Soucaille P. Regulation of metabolic shifts in Clostridium acetobutylicum ATCC 824. FEMS Microbiol Rev. 1995;17(3):287-97.
    • (1995) FEMS Microbiol Rev. , vol.17 , Issue.3 , pp. 287-297
    • Girbal, L.1    Croux, C.2    Vasconcelos, I.3    Soucaille, P.4
  • 22
    • 0030922888 scopus 로고    scopus 로고
    • The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain
    • Cornillot E, Nair RV, Papoutsakis ET, Soucaille P. The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain. J Bacteriol. 1997;179(17):5442-7.
    • (1997) J Bacteriol. , vol.179 , Issue.17 , pp. 5442-5447
    • Cornillot, E.1    Nair, R.V.2    Papoutsakis, E.T.3    Soucaille, P.4
  • 23
    • 0029987804 scopus 로고    scopus 로고
    • Solvent-forming genes in clostridia
    • Cornillot E, Soucaille P. Solvent-forming genes in clostridia. Nature. 1996;380(6574):489-489.
    • (1996) Nature. , vol.380 , Issue.6574 , pp. 489
    • Cornillot, E.1    Soucaille, P.2
  • 24
    • 38049001166 scopus 로고    scopus 로고
    • Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
    • Atsumi S, Hanai T, Liao JC. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature. 2008;451(7174):86-9.
    • (2008) Nature. , vol.451 , Issue.7174 , pp. 86-89
    • Atsumi, S.1    Hanai, T.2    Liao, J.C.3
  • 25
    • 80052029042 scopus 로고    scopus 로고
    • Switching Clostridium acetobutylicum to an ethanol producer by disruption of the butyrate/butanol fermentative pathway
    • Lehmann D, Lutke-Eversloh T. Switching Clostridium acetobutylicum to an ethanol producer by disruption of the butyrate/butanol fermentative pathway. Metab Eng. 2011;13(5):464-73.
    • (2011) Metab Eng. , vol.13 , Issue.5 , pp. 464-473
    • Lehmann, D.1    Lutke-Eversloh, T.2
  • 26
    • 84887028426 scopus 로고    scopus 로고
    • Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress
    • Wang Q, Venkataramanan KP, Huang H, Papoutsakis ET, Wu CH. Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress. BMC Syst Biol. 2013;7:120.
    • (2013) BMC Syst Biol. , vol.7 , pp. 120
    • Wang, Q.1    Venkataramanan, K.P.2    Huang, H.3    Papoutsakis, E.T.4    Wu, C.H.5
  • 27
    • 77950629484 scopus 로고    scopus 로고
    • Metabolite stress and tolerance in the production of biofuels and chemicals: Gene-expression-based systems analysis of butanol, butyrate, and acetate stresses in the anaerobe Clostridium acetobutylicum
    • Alsaker KV, Paredes C, Papoutsakis ET. Metabolite stress and tolerance in the production of biofuels and chemicals: gene-expression-based systems analysis of butanol, butyrate, and acetate stresses in the anaerobe Clostridium acetobutylicum. Biotechnol Bioeng. 2010;105(6):1131-47.
    • (2010) Biotechnol Bioeng. , vol.105 , Issue.6 , pp. 1131-1147
    • Alsaker, K.V.1    Paredes, C.2    Papoutsakis, E.T.3
  • 28
    • 84911806132 scopus 로고    scopus 로고
    • Chemostat cultivation and transcriptional analyses of Clostridium acetobutylicum mutants with defects in the acid and acetone biosynthetic pathways
    • Honicke D, Lutke-Eversloh T, Liu Z, Lehmann D, Liebl W, Ehrenreich A. Chemostat cultivation and transcriptional analyses of Clostridium acetobutylicum mutants with defects in the acid and acetone biosynthetic pathways. Appl Microbiol Biotechnol. 2014;98(23):9777-94.
    • (2014) Appl Microbiol Biotechnol. , vol.98 , Issue.23 , pp. 9777-9794
    • Honicke, D.1    Lutke-Eversloh, T.2    Liu, Z.3    Lehmann, D.4    Liebl, W.5    Ehrenreich, A.6
  • 29
    • 70349288293 scopus 로고    scopus 로고
    • The role of PerR in O2-affected gene expression of Clostridium acetobutylicum
    • Hillmann F, Doring C, Riebe O, Ehrenreich A, Fischer RJ, Bahl H. The role of PerR in O2-affected gene expression of Clostridium acetobutylicum. J Bacteriol. 2009;191(19):6082-93.
    • (2009) J Bacteriol. , vol.191 , Issue.19 , pp. 6082-6093
    • Hillmann, F.1    Doring, C.2    Riebe, O.3    Ehrenreich, A.4    Fischer, R.J.5    Bahl, H.6
  • 30
    • 84865403230 scopus 로고    scopus 로고
    • A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum- Cellular behavior in adaptation to n-butanol
    • Schwarz KM, Kuit W, Grimmler C, Ehrenreich A, Kengen SW. A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum- Cellular behavior in adaptation to n-butanol. J Biotechnol. 2012;161(3):366-77.
    • (2012) J Biotechnol. , vol.161 , Issue.3 , pp. 366-377
    • Schwarz, K.M.1    Kuit, W.2    Grimmler, C.3    Ehrenreich, A.4    Kengen, S.W.5
  • 31
    • 84857087282 scopus 로고    scopus 로고
    • An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum
    • Steiner E, Scott J, Minton NP, Winzer K. An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum. Appl Environ Microbiol. 2012;78(4):1113-22.
    • (2012) Appl Environ Microbiol. , vol.78 , Issue.4 , pp. 1113-1122
    • Steiner, E.1    Scott, J.2    Minton, N.P.3    Winzer, K.4
  • 32
    • 26444483354 scopus 로고    scopus 로고
    • Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum
    • Alsaker KV, Papoutsakis ET. Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum. J Bacteriol. 2005;187(20):7103-18.
    • (2005) J Bacteriol. , vol.187 , Issue.20 , pp. 7103-7118
    • Alsaker, K.V.1    Papoutsakis, E.T.2
  • 33
    • 3042565140 scopus 로고    scopus 로고
    • Transcriptional organization of the Clostridium acetobutylicum genome
    • Paredes CJ, Rigoutsos I, Papoutsakis ET. Transcriptional organization of the Clostridium acetobutylicum genome. Nucleic Acids Res. 2004;32(6):1973-81.
    • (2004) Nucleic Acids Res. , vol.32 , Issue.6 , pp. 1973-1981
    • Paredes, C.J.1    Rigoutsos, I.2    Papoutsakis, E.T.3
  • 34
    • 84914149151 scopus 로고    scopus 로고
    • Simultaneous production of butanol and acetoin by metabolically engineered Clostridium acetobutylicum
    • Liu D, Chen Y, Ding F, Guo T, Xie J, Zhuang W, Niu H, Shi X, Zhu C, Ying H. Simultaneous production of butanol and acetoin by metabolically engineered Clostridium acetobutylicum. Metab Eng. 2015;27:107-14.
    • (2015) Metab Eng. , vol.27 , pp. 107-114
    • Liu, D.1    Chen, Y.2    Ding, F.3    Guo, T.4    Xie, J.5    Zhuang, W.6    Niu, H.7    Shi, X.8    Zhu, C.9    Ying, H.10
  • 35
    • 0034003163 scopus 로고    scopus 로고
    • Analysis of a catabolic operon for sucrose transport and metabolism in Clostridium acetobutylicum ATCC 824
    • Tangney M, Mitchell WJ. Analysis of a catabolic operon for sucrose transport and metabolism in Clostridium acetobutylicum ATCC 824. J Mol Microbiol Biotechnol. 2000;2(1):71-80.
    • (2000) J Mol Microbiol Biotechnol. , vol.2 , Issue.1 , pp. 71-80
    • Tangney, M.1    Mitchell, W.J.2
  • 36
    • 78049506965 scopus 로고    scopus 로고
    • Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum
    • Servinsky MD, Kiel JT, Dupuy NF, Sund CJ. Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum. Microbiology. 2010;156(11):3478-91.
    • (2010) Microbiology. , vol.156 , Issue.11 , pp. 3478-3491
    • Servinsky, M.D.1    Kiel, J.T.2    Dupuy, N.F.3    Sund, C.J.4
  • 37
    • 33746609376 scopus 로고    scopus 로고
    • Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH
    • Fischer RJ, Oehmcke S, Meyer U, Mix M, Schwarz K, Fiedler T, Bahl H. Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH. J Bacteriol. 2006;188(15):5469-78.
    • (2006) J Bacteriol. , vol.188 , Issue.15 , pp. 5469-5478
    • Fischer, R.J.1    Oehmcke, S.2    Meyer, U.3    Mix, M.4    Schwarz, K.5    Fiedler, T.6    Bahl, H.7
  • 38
    • 84956996943 scopus 로고    scopus 로고
    • Construction of a restriction-less, marker-less mutant useful for functional genomic and metabolic engineering of the biofuel producer Clostridium acetobutylicum
    • Croux C, Nguyen NPT, Lee J, Raynaud C, Saint-Prix F, Gonzalez-Pajuelo M, Meynial-Salles I, Soucaille P. Construction of a restriction-less, marker-less mutant useful for functional genomic and metabolic engineering of the biofuel producer Clostridium acetobutylicum. Biotechnol Biofuel. 2016;9:21.
    • (2016) Biotechnol Biofuel. , vol.9 , pp. 21
    • Croux, C.1    Nguyen, N.P.T.2    Lee, J.3    Raynaud, C.4    Saint-Prix, F.5    Gonzalez-Pajuelo, M.6    Meynial-Salles, I.7    Soucaille, P.8
  • 39
    • 84876863362 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicum ATCC 824 for the high-yield production of a biofuel composed of an isopropanol/butanol/ethanol mixture
    • Dusseaux S, Croux C, Soucaille P, Meynial-Salles I. Metabolic engineering of Clostridium acetobutylicum ATCC 824 for the high-yield production of a biofuel composed of an isopropanol/butanol/ethanol mixture. Metab Eng. 2013;18:1-8.
    • (2013) Metab Eng. , vol.18 , pp. 1-8
    • Dusseaux, S.1    Croux, C.2    Soucaille, P.3    Meynial-Salles, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.