메뉴 건너뛰기




Volumn 6, Issue 6, 2015, Pages

A quantitative system-scale characterization of the metabolism of clostridium acetobutylicum

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRYL COENZYME A DEHYDROGENASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROGENASE; MESSENGER RNA; PROTEOME;

EID: 84952802569     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01808-15     Document Type: Article
Times cited : (62)

References (82)
  • 1
    • 33846791387 scopus 로고    scopus 로고
    • Applied acetone-butanol fermentation
    • In Bahl H, Dürre P (ed), Wiley-VCH Verlag GmbH, Weinheim, Germany
    • Jones DT. 2001. Applied acetone-butanol fermentation, p 125-168. In Bahl H, Dürre P (ed), Clostridia: biotechnology and medical applications. Wiley-VCH Verlag GmbH, Weinheim, Germany.
    • (2001) Clostridia: Biotechnology and medical applications , pp. 125-168
    • Jones, D.T.1
  • 2
    • 0022970603 scopus 로고
    • Acetone-butanol fermentation revisited
    • Jones DT, Woods DR. 1986. Acetone-butanol fermentation revisited. Microbiol Res 50:484-524.
    • (1986) Microbiol Res , vol.50 , pp. 484-524
    • Jones, D.T.1    Woods, D.R.2
  • 4
    • 38149030843 scopus 로고    scopus 로고
    • Biobutanol: An attractive biofuel
    • Dürre P. 2007. Biobutanol: an attractive biofuel. Biotechnol J 2:1525-1534. http://dx.doi.org/10.1002/biot.200700168.
    • (2007) Biotechnol J , vol.2 , pp. 1525-1534
    • Dürre, P.1
  • 5
    • 67349164687 scopus 로고    scopus 로고
    • Recent progress on industrial fermentative production of acetone-butanol-ethanol by Clostridium acetobutylicum in China
    • Ni Y, Sun Z. 2009. Recent progress on industrial fermentative production of acetone-butanol-ethanol by Clostridium acetobutylicum in China. Appl Microbiol Biotechnol 83:415-423. http://dx.doi.org/10.1007/s00253-009-2003-y.
    • (2009) Appl Microbiol Biotechnol , vol.83 , pp. 415-423
    • Ni, Y.1    Sun, Z.2
  • 6
    • 0028201690 scopus 로고
    • Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol
    • Vasconcelos I, Girbal L, Soucaille P. 1994. Regulation of carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH on mixtures of glucose and glycerol. J Bacteriol 176: 1443-1450.
    • (1994) J Bacteriol , vol.176 , pp. 1443-1450
    • Vasconcelos, I.1    Girbal, L.2    Soucaille, P.3
  • 7
    • 0028036995 scopus 로고
    • Regulation of Clostridium acetobutylicum metabolism as revealed by mixed-substrate steady-state continuous cultures: Role of NADH/NAD ratio and ATP pool
    • Girbal L, Soucaille P. 1994. Regulation of Clostridium acetobutylicum metabolism as revealed by mixed-substrate steady-state continuous cultures: role of NADH/NAD ratio and ATP pool. J Bacteriol 176: 6433-6438.
    • (1994) J Bacteriol , vol.176 , pp. 6433-6438
    • Girbal, L.1    Soucaille, P.2
  • 8
    • 0028907367 scopus 로고
    • How neutral red modified carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH
    • Girbal L, Vasconcelos I, Saint-Amans S, Soucaille P. 1995. How neutral red modified carbon and electron flow in Clostridium acetobutylicum grown in chemostat culture at neutral pH. FEMS Microbiol Rev 16: 151-162. http://dx.doi.org/10.1111/j.1574-6976.1995.tb00163.x.
    • (1995) FEMS Microbiol Rev , vol.16 , pp. 151-162
    • Girbal, L.1    Vasconcelos, I.2    Saint-Amans, S.3    Soucaille, P.4
  • 9
    • 0028791403 scopus 로고
    • Regulation of metabolic shifts in Clostridium acetobutylicum ATCC 824
    • Girbal L, Croux C, Vasconcelos I, Soucaille P. 1995. Regulation of metabolic shifts in Clostridium acetobutylicum ATCC 824. FEMS Microbiol Rev 17:287-297. http://dx.doi. org/1 0. 1111 / j. 1 5 7 4-6976.1995.tb00212.x.
    • (1995) FEMS Microbiol Rev , vol.17 , pp. 287-297
    • Girbal, L.1    Croux, C.2    Vasconcelos, I.3    Soucaille, P.4
  • 10
    • 0031885009 scopus 로고    scopus 로고
    • Regulation of solvent production in Clostridium acetobutylicum
    • Girbal L, Soucaille P. 1998. Regulation of solvent production in Clostridium acetobutylicum. Trends Biotechnol 16:11-16. http://dx.doi.org/ 10.1016/S0167-7799(97)01141-4.
    • (1998) Trends Biotechnol , vol.16 , pp. 11-16
    • Girbal, L.1    Soucaille, P.2
  • 11
    • 0024615960 scopus 로고
    • Phosphotransbutyrylase from Clostridium acetobutylicum ATCC 824 and its role in acidogenesis
    • Wiesenborn DP, Rudolph FB, Papoutsakis ET. 1989. Phosphotransbutyrylase from Clostridium acetobutylicum ATCC 824 and its role in acidogenesis. Appl Environ Microbiol 55:317-322.
    • (1989) Appl Environ Microbiol , vol.55 , pp. 317-322
    • Wiesenborn, D.P.1    Rudolph, F.B.2    Papoutsakis, E.T.3
  • 12
    • 0024616857 scopus 로고
    • Coenzyme A transferase from Clostridium acetobutylicum ATCC 824 and its role in the uptake of acids
    • Wiesenborn DP, Rudolph FB, Papoutsakis ET. 1989. Coenzyme A transferase from Clostridium acetobutylicum ATCC 824 and its role in the uptake of acids. Appl Environ Microbiol 55:323-329.
    • (1989) Appl Environ Microbiol , vol.55 , pp. 323-329
    • Wiesenborn, D.P.1    Rudolph, F.B.2    Papoutsakis, E.T.3
  • 13
    • 0028830955 scopus 로고
    • Differential induction of genes related to solvent formation during the shift from acidogenesis to solventogenesis in continuous culture of Clostridium acetobutylicum
    • Sauer U, Dürre P. 1995. Differential induction of genes related to solvent formation during the shift from acidogenesis to solventogenesis in continuous culture of Clostridium acetobutylicum. FEMS Microbiol Lett 125: 115-120. http://dx.doi.org/10.1111/j.1574-6968.1995.tb07344.x.
    • (1995) FEMS Microbiol Lett , vol.125 , pp. 115-120
    • Sauer, U.1    Dürre, P.2
  • 14
    • 84865423798 scopus 로고    scopus 로고
    • A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum-solvent stress caused by a transient n-butanol pulse
    • Janssen H, Grimmler C, Ehrenreich A, Bahl H, Fischer R. 2012. A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum-solvent stress caused by a transient n-butanol pulse. J Biotechnol 161:354-365. http://dx.doi.org/10.1016/j.jbiotec.2012.03.027.
    • (2012) J Biotechnol , vol.161 , pp. 354-365
    • Janssen, H.1    Grimmler, C.2    Ehrenreich, A.3    Bahl, H.4    Fischer, R.5
  • 15
    • 84865403230 scopus 로고    scopus 로고
    • A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum-cellular behavior in adaptation to n-butanol
    • Schwarz KM, Kuit W, Grimmler C, Ehrenreich A, Kengen SWM. 2012. A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum-cellular behavior in adaptation to n-butanol. J Biotechnol 161:366-377. http://dx.doi.org/10.1016/j.jbiotec.2012.03.018.
    • (2012) J Biotechnol , vol.161 , pp. 366-377
    • Schwarz, K.M.1    Kuit, W.2    Grimmler, C.3    Ehrenreich, A.4    Kengen, S.W.M.5
  • 16
    • 84887028426 scopus 로고    scopus 로고
    • Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress
    • Wang Q, Venkataramanan K, Huang H, Papoutsakis ET, Wu CH. 2013. Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress. BMC Syst Biol 7:120. http://dx.doi.org/10.1186/ 1752-0509-7-120.
    • (2013) BMC Syst Biol , vol.7 , pp. 120
    • Wang, Q.1    Venkataramanan, K.2    Huang, H.3    Papoutsakis, E.T.4    Wu, C.H.5
  • 17
    • 84888800671 scopus 로고    scopus 로고
    • The clostridium small RNome that responds to stress: The paradigm and importance of toxic metabolite stress in C. acetobutylicum
    • Venkataramanan KP, Jones SW, McCormick KP, Kunjeti SG, Ralston MT, Meyers BC, Papoutsakis ET. 2013. The clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum. BMC Genomics 14:849. http://dx.doi.org/ 10.1186/1471-2164-14-849.
    • (2013) BMC Genomics , vol.14 , pp. 849
    • Venkataramanan, K.P.1    Jones, S.W.2    McCormick, K.P.3    Kunjeti, S.G.4    Ralston, M.T.5    Meyers, B.C.6    Papoutsakis, E.T.7
  • 18
    • 0029987804 scopus 로고    scopus 로고
    • Solvent-forming genes in Clostridia
    • Cornillot E, Soucaille P. 1996. Solvent-forming genes in Clostridia. Nature 380:489. http://dx.doi.org/10.1038/380489a0.
    • (1996) Nature , vol.380 , pp. 489
    • Cornillot, E.1    Soucaille, P.2
  • 19
    • 0030922888 scopus 로고    scopus 로고
    • The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain
    • Cornillot E, Nair RV, Papoutsakis ET, Soucaille P. 1997. The genes for butanol and acetone formation in Clostridium acetobutylicum ATCC 824 reside on a large plasmid whose loss leads to degeneration of the strain. J Bacteriol 179:5442-5447.
    • (1997) J Bacteriol , vol.179 , pp. 5442-5447
    • Cornillot, E.1    Nair, R.V.2    Papoutsakis, E.T.3    Soucaille, P.4
  • 21
    • 26444483354 scopus 로고    scopus 로고
    • Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum
    • Alsaker KV, Papoutsakis ET. 2005. Transcriptional program of early sporulation and stationary-phase events in Clostridium acetobutylicum. J Bacteriol 187:7103-7118. http://dx.doi.org/10.1128/JB.187.20.7103-7118.2005.
    • (2005) J Bacteriol , vol.187 , pp. 7103-7118
    • Alsaker, K.V.1    Papoutsakis, E.T.2
  • 22
    • 77955559194 scopus 로고    scopus 로고
    • A proteomic and transcriptional view of acidogenic and solventogenic steady-state cells of Clostridium acetobutylicum in a chemostat culture
    • Janssen H, Döring C, Ehrenreich A, Voigt B, Hecker M, Bahl H, Fischer R. 2010. A proteomic and transcriptional view of acidogenic and solventogenic steady-state cells of Clostridium acetobutylicum in a chemostat culture. Appl Microbiol Biotechnol 87:2209-2226. http://dx.doi.org/ 10.1007/s00253-010-2741-x.
    • (2010) Appl Microbiol Biotechnol , vol.87 , pp. 2209-2226
    • Janssen, H.1    Döring, C.2    Ehrenreich, A.3    Voigt, B.4    Hecker, M.5    Bahl, H.6    Fischer, R.7
  • 24
    • 33644765063 scopus 로고    scopus 로고
    • Proteome analysis and comparison of Clostridium acetobutylicum ATCC 824 and Spo0A strain variants
    • Sullivan L, Bennett GN. 2006. Proteome analysis and comparison of Clostridium acetobutylicum ATCC 824 and Spo0A strain variants. J Ind Microbiol Biotechnol 33:298-308. http://dx.doi.org/10.1007/s10295-005-0050-7.
    • (2006) J Ind Microbiol Biotechnol , vol.33 , pp. 298-308
    • Sullivan, L.1    Bennett, G.N.2
  • 25
    • 0038782128 scopus 로고    scopus 로고
    • DNA array-based transcriptional analysis of asporogenous, nonsolventogenic Clostridium acetobutylicum strains SKO1 and M5
    • Tomas CA, Alsaker KV, Bonarius HPJ, Hendriksen WT, Yang H, Beamish JA, Paredes CJ, Papoutsakis ET. 2003. DNA array-based transcriptional analysis of asporogenous, nonsolventogenic Clostridium acetobutylicum strains SKO1 and M5. J Bacteriol 185:4539-4547. http:// dx.doi.org/10.1128/JB.185.15.4539-4547.2003.
    • (2003) J Bacteriol , vol.185 , pp. 4539-4547
    • Tomas, C.A.1    Alsaker, K.V.2    Bonarius, H.P.J.3    Hendriksen, W.T.4    Yang, H.5    Beamish, J.A.6    Paredes, C.J.7    Papoutsakis, E.T.8
  • 26
    • 0036146379 scopus 로고    scopus 로고
    • Changes in protein synthesis and identification of proteins specifically induced during solventogenesis in Clostridium acetobutylicum
    • Schaffer S, Isci N, Zickner B, Dürre P. 2002. Changes in protein synthesis and identification of proteins specifically induced during solventogenesis in Clostridium acetobutylicum. Electrophoresis 23:110-121. http:// dx.doi. org/1 0. 1 0 0 2 / 1 5 2 2-2 6 8 3 ( 2 0 0 2 0 1 ) 2 3: 1_110::AID-ELPS110_3.0.CO;2-G.
    • (2002) Electrophoresis , vol.23 , pp. 110-121
    • Schaffer, S.1    Isci, N.2    Zickner, B.3    Dürre, P.4
  • 27
    • 34547180289 scopus 로고    scopus 로고
    • Ageneral framework for designing and validating oligomer-basedDNA microarrays and its application to Clostridium acetobutylicum
    • Paredes CJ, Senger RS, Spath IS, Borden JR, Sillers R, Papoutsakis ET. 2007.Ageneral framework for designing and validating oligomer-basedDNA microarrays and its application to Clostridium acetobutylicum. Appl Environ Microbiol 73:4631-4638. http://dx.doi.org/10.1128/AEM.00144-07.
    • (2007) Appl Environ Microbiol , vol.73 , pp. 4631-4638
    • Paredes, C.J.1    Senger, R.S.2    Spath, I.S.3    Borden, J.R.4    Sillers, R.5    Papoutsakis, E.T.6
  • 28
    • 78049506965 scopus 로고    scopus 로고
    • Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum
    • Servinsky MD, Kiel JT, Dupuy NF, Sund CJ. 2010. Transcriptional analysis of differential carbohydrate utilization by Clostridium acetobutylicum. Microbiology 156:3478-3491. http://dx.doi.org/10.1099/ mic.0.037085-0.
    • (2010) Microbiology , vol.156 , pp. 3478-3491
    • Servinsky, M.D.1    Kiel, J.T.2    Dupuy, N.F.3    Sund, C.J.4
  • 29
    • 78149464840 scopus 로고    scopus 로고
    • Transcriptional analysis of catabolite repression in Clostridium acetobutylicum growing on mixtures of D-glucose and D-xylose
    • Grimmler C, Held C, Liebl W, Ehrenreich A. 2010. Transcriptional analysis of catabolite repression in Clostridium acetobutylicum growing on mixtures of D-glucose and D-xylose. J Biotechnol 150:315-323. http:// dx.doi.org/10.1016/j.jbiotec.2010.09.938.
    • (2010) J Biotechnol , vol.150 , pp. 315-323
    • Grimmler, C.1    Held, C.2    Liebl, W.3    Ehrenreich, A.4
  • 30
    • 84928124725 scopus 로고    scopus 로고
    • Comparative transcriptome analysis between csrA-disruption Clostridium acetobutylicum and its parent strain
    • Tan Y, Liu Z, Liu Z, Zheng H, Li F. 2015. Comparative transcriptome analysis between csrA-disruption Clostridium acetobutylicum and its parent strain. Mol Biosyst 11:1434-1442. http://dx.doi.org/10.1039/ C4MB00600C.
    • (2015) Mol Biosyst , vol.11 , pp. 1434-1442
    • Tan, Y.1    Liu, Z.2    Liu, Z.3    Zheng, H.4    Li, F.5
  • 31
    • 77954604280 scopus 로고    scopus 로고
    • Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield
    • Mao S, Luo Y, Zhang T, Li J, Bao G, Zhu Y, Chen Z, Zhang Y, Li Y, Ma Y. 2010. Proteome reference map and comparative proteomic analysis between a wild type Clostridium acetobutylicum DSM 1731 and its mutant with enhanced butanol tolerance and butanol yield. J Proteome Res 9:3046-3061. http://dx.doi.org/10.1021/pr9012078.
    • (2010) J Proteome Res , vol.9 , pp. 3046-3061
    • Mao, S.1    Luo, Y.2    Zhang, T.3    Li, J.4    Bao, G.5    Zhu, Y.6    Chen, Z.7    Zhang, Y.8    Li, Y.9    Ma, Y.10
  • 32
    • 79954526956 scopus 로고    scopus 로고
    • Comparative analysis on the membrane proteome of Clostridium acetobutylicum wild type strain and its butanol-tolerant mutant
    • Mao S, Luo Y, Bao G, Zhang Y, Li Y, Ma Y. 2011. Comparative analysis on the membrane proteome of Clostridium acetobutylicum wild type strain and its butanol-tolerant mutant. Mol Biosyst 7:1660-1677. http:// dx.doi.org/10.1039/c0mb00330a.
    • (2011) Mol Biosyst , vol.7 , pp. 1660-1677
    • Mao, S.1    Luo, Y.2    Bao, G.3    Zhang, Y.4    Li, Y.5    Ma, Y.6
  • 33
    • 84901610547 scopus 로고    scopus 로고
    • Proteomic analyses of the phase transition from acidogenesis to solventogenesis using solventogenic and non-solventogenic Clostridium acetobutylicum strains
    • Jang Y, Han M, Lee J, Im JA, Lee YH, Papoutsakis ET, Bennett G, Lee SY. 2014. Proteomic analyses of the phase transition from acidogenesis to solventogenesis using solventogenic and non-solventogenic Clostridium acetobutylicum strains. Appl Microbiol Biotechnol 98:5105-5115. http:// dx.doi.org/10.1007/s00253-014-5738-z.
    • (2014) Appl Microbiol Biotechnol , vol.98 , pp. 5105-5115
    • Jang, Y.1    Han, M.2    Lee, J.3    Im, J.A.4    Lee, Y.H.5    Papoutsakis, E.T.6    Bennett, G.7    Lee, S.Y.8
  • 35
    • 80054111671 scopus 로고    scopus 로고
    • Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose
    • Sivagnanam K, Raghavan VG, Shah M, Hettich RL, Verberkmoes NC, Lefsrud MG. 2011. Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. Proteome Sci 9:66. http://dx.doi.org/10.1186/1477-5956-9-66.
    • (2011) Proteome Sci , vol.9 , pp. 66
    • Sivagnanam, K.1    Raghavan, V.G.2    Shah, M.3    Hettich, R.L.4    Verberkmoes, N.C.5    Lefsrud, M.G.6
  • 36
    • 84879563967 scopus 로고    scopus 로고
    • Workflow for quantitative proteomic analysis of Clostridium acetobutylicum ATCC 824 using iTRAQ tags
    • Hou S, Jones SW, Choe LH, Papoutsakis ET, Lee KH. 2013. Workflow for quantitative proteomic analysis of Clostridium acetobutylicum ATCC 824 using iTRAQ tags. Methods 61:269-276. http://dx.doi.org/10.1016/ j.ymeth.2013.03.013.
    • (2013) Methods , vol.61 , pp. 269-276
    • Hou, S.1    Jones, S.W.2    Choe, L.H.3    Papoutsakis, E.T.4    Lee, K.H.5
  • 37
    • 78650924319 scopus 로고    scopus 로고
    • Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis in continuous cultures of Clostridium acetobutylicum
    • Grimmler C, Janssen H, Krau_e D, Fischer R, Bahl H, Dürre P, Liebl W, Ehrenreich A. 2011. Genome-wide gene expression analysis of the switch between acidogenesis and solventogenesis in continuous cultures of Clostridium acetobutylicum. J Mol Microbiol Biotechnol 20:1-15. http://dx.doi.org/10.1159/000320973.
    • (2011) J Mol Microbiol Biotechnol , vol.20 , pp. 1-15
    • Grimmler, C.1    Janssen, H.2    Krau_e, D.3    Fischer, R.4    Bahl, H.5    Dürre, P.6    Liebl, W.7    Ehrenreich, A.8
  • 38
    • 79952399941 scopus 로고    scopus 로고
    • Inactivation of sigmaE and sigmaG in Clostridium acetobutylicum illuminates their roles in clostridialcell-form biogenesis, granulose synthesis, solventogenesis, and spore morphogenesis
    • Tracy BP, Jones SW, Papoutsakis ET. 2011. Inactivation of sigmaE and sigmaG in Clostridium acetobutylicum illuminates their roles in clostridialcell-form biogenesis, granulose synthesis, solventogenesis, and spore morphogenesis. J Bacteriol 193:1414-1426. http://dx.doi.org/10.1128/ JB.01380-10.
    • (2011) J Bacteriol , vol.193 , pp. 1414-1426
    • Tracy, B.P.1    Jones, S.W.2    Papoutsakis, E.T.3
  • 39
    • 79956108383 scopus 로고    scopus 로고
    • Inactivation of sigmaF in Clostridium acetobutylicum ATCC 824 blocks sporulation prior to asymmetric division and abolishes sigmaE and sigmaG protein expression but does not block solvent formation
    • Jones SW, Tracy BP, Gaida SM, Papoutsakis ET. 2011. Inactivation of sigmaF in Clostridium acetobutylicum ATCC 824 blocks sporulation prior to asymmetric division and abolishes sigmaE and sigmaG protein expression but does not block solvent formation. J Bacteriol 193:2429-2440. http://dx.doi.org/10.1128/JB.00088-11.
    • (2011) J Bacteriol , vol.193 , pp. 2429-2440
    • Jones, S.W.1    Tracy, B.P.2    Gaida, S.M.3    Papoutsakis, E.T.4
  • 40
    • 84938928334 scopus 로고    scopus 로고
    • Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum
    • Venkataramanan KP, Min L, Hou S, Jones SW, Ralston MT, Lee KH, Papoutsakis ET. 2015. Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum. Biotechnol Biofuels 8:1-29. http://dx.doi.org/10.1186/s13068-015-0260-9.
    • (2015) Biotechnol Biofuels , vol.8 , pp. 1-29
    • Venkataramanan, K.P.1    Min, L.2    Hou, S.3    Jones, S.W.4    Ralston, M.T.5    Lee, K.H.6    Papoutsakis, E.T.7
  • 41
    • 0020358856 scopus 로고
    • Continuous production of acetone and butanol by Clostridium acetobutylicum in a two-stage phosphate limited chemostat
    • Bahl H, Andersch W, Gottschalk G. 1982. Continuous production of acetone and butanol by Clostridium acetobutylicum in a two-stage phosphate limited chemostat. Eur J Appl Microbiol Biotechnol 15:201-205. http://dx.doi.org/10.1007/BF00499955.
    • (1982) Eur J Appl Microbiol Biotechnol , vol.15 , pp. 201-205
    • Bahl, H.1    Andersch, W.2    Gottschalk, G.3
  • 42
    • 0030059857 scopus 로고    scopus 로고
    • Cloning, sequencing, and expression of clustered genes encoding beta-hydroxybutyryl-coenzyme A (CoA) dehydrogenase, crotonase, and butyryl-CoA dehydrogenase from Clostridium acetobutylicum ATCC 824
    • Boynton ZL, Bennet GN, Rudolph FB. 1996. Cloning, sequencing, and expression of clustered genes encoding beta-hydroxybutyryl-coenzyme A (CoA) dehydrogenase, crotonase, and butyryl-CoA dehydrogenase from Clostridium acetobutylicum ATCC 824. J Bacteriol 178:3015-3024.
    • (1996) J Bacteriol , vol.178 , pp. 3015-3024
    • Boynton, Z.L.1    Bennet, G.N.2    Rudolph, F.B.3
  • 43
    • 38649099718 scopus 로고    scopus 로고
    • Coupled ferredoxin and crotonyl coenzyme A (CoA) reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri
    • Li F, Hinderberger J, Seedorf H, Zhang J, Buckel W, Thauer RK. 2008. Coupled ferredoxin and crotonyl coenzyme A (CoA) reduction with NADH catalyzed by the butyryl-CoA dehydrogenase/Etf complex from Clostridium kluyveri. J Bacteriol 190:843-850. http://dx.doi.org/10.1128/ JB.01417-07.
    • (2008) J Bacteriol , vol.190 , pp. 843-850
    • Li, F.1    Hinderberger, J.2    Seedorf, H.3    Zhang, J.4    Buckel, W.5    Thauer, R.K.6
  • 44
    • 57049169148 scopus 로고    scopus 로고
    • Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance
    • Sillers R, Chow A, Tracy B, Papoutsakis ET. 2008. Metabolic engineering of the non-sporulating, non-solventogenic Clostridium acetobutylicum strain M5 to produce butanol without acetone demonstrate the robustness of the acid-formation pathways and the importance of the electron balance. Metab Eng 10:321-332. http://dx.doi.org/10.1016/ j.ymben.2008.07.005.
    • (2008) Metab Eng , vol.10 , pp. 321-332
    • Sillers, R.1    Chow, A.2    Tracy, B.3    Papoutsakis, E.T.4
  • 45
    • 84988815635 scopus 로고    scopus 로고
    • Capturing the response of Clostridium acetobutylicum to chemical stressors using a regulated genome-scale metabolic model
    • Dash S, Mueller TJ, Venkataramanan KP, Papoutsakis ET, Maranas CD. 2014. Capturing the response of Clostridium acetobutylicum to chemical stressors using a regulated genome-scale metabolic model. Biotechnol Biofuels 7:144. http://dx.doi.org/10.1186/s13068-014-0144-4.
    • (2014) Biotechnol Biofuels , vol.7 , pp. 144
    • Dash, S.1    Mueller, T.J.2    Venkataramanan, K.P.3    Papoutsakis, E.T.4    Maranas, C.D.5
  • 46
    • 84860822839 scopus 로고    scopus 로고
    • Genome-scale modeling using flux ratio constraints to enable metabolic engineering of clostridial metabolism in silico
    • McAnulty MJ, Yen JY, Freedman BG, Senger RS. 2012. Genome-scale modeling using flux ratio constraints to enable metabolic engineering of clostridial metabolism in silico. BMC Syst Biol 6:42. http://dx.doi.org/ 10.1186/1752-0509-6-42.
    • (2012) BMC Syst Biol , vol.6 , pp. 42
    • McAnulty, M.J.1    Yen, J.Y.2    Freedman, B.G.3    Senger, R.S.4
  • 47
    • 0027957210 scopus 로고
    • Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824
    • Nair RV, Bennett GN, Papoutsakis ET. 1994. Molecular characterization of an aldehyde/alcohol dehydrogenase gene from Clostridium acetobutylicum ATCC 824. J Bacteriol 176:871-885.
    • (1994) J Bacteriol , vol.176 , pp. 871-885
    • Nair, R.V.1    Bennett, G.N.2    Papoutsakis, E.T.3
  • 48
    • 0027383357 scopus 로고
    • Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis
    • Fischer RJ, Helms J, Durre P. 1993. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis. J Bacteriol 175:6959-6969.
    • (1993) J Bacteriol , vol.175 , pp. 6959-6969
    • Fischer, R.J.1    Helms, J.2    Durre, P.3
  • 49
    • 0026563908 scopus 로고
    • Molecular characterization of two Clostridium acetobutylicum ATCC 824 butanol dehydrogenase isozyme genes
    • Walter KA, Bennett GN, Papoutsakis ET. 1992. Molecular characterization of two Clostridium acetobutylicum ATCC 824 butanol dehydrogenase isozyme genes. J Bacteriol 174:7149-7158.
    • (1992) J Bacteriol , vol.174 , pp. 7149-7158
    • Walter, K.A.1    Bennett, G.N.2    Papoutsakis, E.T.3
  • 50
    • 0024454383 scopus 로고
    • Purification and characterization of the NADH-dependent butanol dehydrogenase from Clostridium acetobutylicum (ATCC 824)
    • Welch RW, Rudolph FB, Papoutsakis ET. 1989. Purification and characterization of the NADH-dependent butanol dehydrogenase from Clostridium acetobutylicum (ATCC 824). Arch Biochem Biophys 273: 309-318. http://dx.doi.org/10.1016/0003-9861(89)90489-X.
    • (1989) Arch Biochem Biophys , vol.273 , pp. 309-318
    • Welch, R.W.1    Rudolph, F.B.2    Papoutsakis, E.T.3
  • 52
    • 0006699878 scopus 로고
    • Enzymatic investigations on butanol dehydrogenase and butyraldehyde dehydrogenase in extracts of Clostridium acetobutylicum
    • Durre P, Kuhn A, Gottwald M, Gottschalk G. 1987. Enzymatic investigations on butanol dehydrogenase and butyraldehyde dehydrogenase in extracts of Clostridium acetobutylicum. Appl Microbiol Biotechnol 26: 268-272. http://dx.doi.org/10.1007/BF00286322.
    • (1987) Appl Microbiol Biotechnol , vol.26 , pp. 268-272
    • Durre, P.1    Kuhn, A.2    Gottwald, M.3    Gottschalk, G.4
  • 53
    • 0019309213 scopus 로고
    • Affinity purification of glutamate synthase from Escherichia coli
    • Schmidt CNG, Jervis L. 1980. Affinity purification of glutamate synthase from Escherichia coli. Anal Biochem 104:127-129. http://dx.doi.org/ 10.1016/0003-2697(80)90286-9.
    • (1980) Anal Biochem , vol.104 , pp. 127-129
    • Schmidt, C.N.G.1    Jervis, L.2
  • 54
    • 0016697801 scopus 로고
    • Glutamate dehydrogenase from Escherichia coli: Purification and properties
    • Sakamoto N, Kotre AM, Savageau MA. 1975. Glutamate dehydrogenase from Escherichia coli: purification and properties. J Bacteriol 124:775-783.
    • (1975) J Bacteriol , vol.124 , pp. 775-783
    • Sakamoto, N.1    Kotre, A.M.2    Savageau, M.A.3
  • 55
    • 77956511890 scopus 로고    scopus 로고
    • Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum
    • Amador-Noguez D, Feng X, Fan J, Roquet N, Rabitz H, Rabinowitz JD. 2010. Systems-level metabolic flux profiling elucidates a complete, bifurcated tricarboxylic acid cycle in Clostridium acetobutylicum. J Bacteriol 192:4452-4461. http://dx.doi.org/10.1128/JB.00490-10.
    • (2010) J Bacteriol , vol.192 , pp. 4452-4461
    • Amador-Noguez, D.1    Feng, X.2    Fan, J.3    Roquet, N.4    Rabitz, H.5    Rabinowitz, J.D.6
  • 56
    • 51849142353 scopus 로고    scopus 로고
    • Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis
    • Senger RS, Papoutsakis ET. 2008. Genome-scale model for Clostridium acetobutylicum: part I. Metabolic network resolution and analysis. Biotechnol Bioeng 101:1036-1052. http://dx.doi.org/10.1002/bit.22010.
    • (2008) Biotechnol Bioeng , vol.101 , pp. 1036-1052
    • Senger, R.S.1    Papoutsakis, E.T.2
  • 57
    • 51849157931 scopus 로고    scopus 로고
    • Genome-scale model for Clostridium acetobutylicum: Part II. Development of specific proton flux states and numerically determined sub-systems
    • Senger RS, Papoutsakis ET. 2008. Genome-scale model for Clostridium acetobutylicum: part II. Development of specific proton flux states and numerically determined sub-systems. Biotechnol Bioeng 101:1053-1071. http://dx.doi.org/10.1002/bit.22009.
    • (2008) Biotechnol Bioeng , vol.101 , pp. 1053-1071
    • Senger, R.S.1    Papoutsakis, E.T.2
  • 58
    • 51849115840 scopus 로고    scopus 로고
    • Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network
    • Lee J, Yun H, Feist AM, Palsson BØ, Lee SY. 2008. Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network. Appl Microbiol Biotechnol 80:849-862. http://dx.doi.org/10.1007/s00253-008-1654-4.
    • (2008) Appl Microbiol Biotechnol , vol.80 , pp. 849-862
    • Lee, J.1    Yun, H.2    Feist, A.M.3    Palsson, B.Ø.4    Lee, S.Y.5
  • 59
    • 0034606690 scopus 로고    scopus 로고
    • Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: Need for new phenomenological models for solventogenesis and butanol inhibition?
    • Harris LM, Desai RP, Welker NE, Papoutsakis ET. 2000. Characterization of recombinant strains of the Clostridium acetobutylicum butyrate kinase inactivation mutant: need for new phenomenological models for solventogenesis and butanol inhibition? Biotechnol Bioeng 67:1-11. http://dx.doi.org/10.1002/(SICI)1097-0290(20000105)67:1_1::AID-BIT1_3.0.CO;2-G.
    • (2000) Biotechnol Bioeng , vol.67 , pp. 1-11
    • Harris, L.M.1    Desai, R.P.2    Welker, N.E.3    Papoutsakis, E.T.4
  • 60
    • 70449575862 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicumM5for highly selective butanol production
    • Lee JY, Jang Y, Lee J, Papoutsakis ET, Lee SY. 2009. Metabolic engineering of Clostridium acetobutylicumM5for highly selective butanol production. Biotechnol J 4:1432-1440. http://dx.doi.org/10.1002/ biot.200900142.
    • (2009) Biotechnol J , vol.4 , pp. 1432-1440
    • Lee, J.Y.1    Jang, Y.2    Lee, J.3    Papoutsakis, E.T.4    Lee, S.Y.5
  • 61
    • 0002437481 scopus 로고    scopus 로고
    • Chemical composition of E. coli
    • In Neidhardt FC, Curtiss R, III, Ingraham JL, Lin ECC, Low KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE (ed), 2nd ed. American Society for Microbiology, Washington, DC
    • Neidhardt FC, Umbarger HE. 1996. Chemical composition of E. coli, p 13-16. In Neidhardt FC, Curtiss R, III, Ingraham JL, Lin ECC, Low KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE (ed), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. American Society for Microbiology, Washington, DC.
    • (1996) Escherichia coli and Salmonella: Cellular and molecular biology , pp. 13-16
    • Neidhardt, F.C.1    Umbarger, H.E.2
  • 62
    • 0343035686 scopus 로고    scopus 로고
    • Stoichiometric model of Escherichia coli metabolism: Incorporation of growth-rate dependent biomass composition and mechanistic energy requirements
    • Pramanik J, Keasling JD. 1997. Stoichiometric model of Escherichia coli metabolism: incorporation of growth-rate dependent biomass composition and mechanistic energy requirements. Biotechnol Bioeng 56: 398-421.
    • (1997) Biotechnol Bioeng , vol.56 , pp. 398-421
    • Pramanik, J.1    Keasling, J.D.2
  • 63
  • 65
    • 0000640710 scopus 로고    scopus 로고
    • Modulation of chemical composition and other parameters of the cell by growth rate
    • In Neidhardt FC, Curtiss R, III, Ingraham JL, Lin ECC, Low KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE (ed), 2nd ed. American Society for Microbiology, Washington, DC
    • Bremer H, Dennis PP. 1996. Modulation of chemical composition and other parameters of the cell by growth rate, p 1553-1569. In Neidhardt FC, Curtiss R, III, Ingraham JL, Lin ECC, Low KB, Magasanik B, Reznikoff WS, Riley M, Schaechter M, Umbarger HE (ed), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. American Society for Microbiology, Washington, DC.
    • (1996) Escherichia coli and Salmonella: Cellular and molecular biology , pp. 1553-1569
    • Bremer, H.1    Dennis, P.P.2
  • 66
    • 0036180998 scopus 로고    scopus 로고
    • Molecular characterization and transcriptional analysis of adhE2, the gene encoding the NADH-dependent aldehyde/alcohol dehydrogenase responsible for butanol production in alcohologenic cultures of Clostridium acetobutylicum ATCC 824
    • Fontaine L, Meynial-Salles I, Girbal L, Yang X, Croux C, Soucaille P. 2002. Molecular characterization and transcriptional analysis of adhE2, the gene encoding the NADH-dependent aldehyde/alcohol dehydrogenase responsible for butanol production in alcohologenic cultures of Clostridium acetobutylicum ATCC 824. J Bacteriol 184:821-830. http:// dx.doi.org/10.1128/JB.184.3.821-830.2002.
    • (2002) J Bacteriol , vol.184 , pp. 821-830
    • Fontaine, L.1    Meynial-Salles, I.2    Girbal, L.3    Yang, X.4    Croux, C.5    Soucaille, P.6
  • 67
    • 83055188821 scopus 로고    scopus 로고
    • Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum
    • Amador-Noguez D, Brasg IA, Feng X, Roquet N, Rabinowitz JD. 2011. Metabolome remodeling during the acidogenic-solventogenic transition in Clostridium acetobutylicum. Appl Environ Microbiol 77:7984-7997. http://dx.doi.org/10.1128/AEM.05374-11.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 7984-7997
    • Amador-Noguez, D.1    Brasg, I.A.2    Feng, X.3    Roquet, N.4    Rabinowitz, J.D.5
  • 68
    • 0037137211 scopus 로고    scopus 로고
    • Characterization of the cellulolytic complex (cellulosome) of Clostridium acetobutylicum
    • Sabathé F, Bélaïch A, Soucaille P. 2002. Characterization of the cellulolytic complex (cellulosome) of Clostridium acetobutylicum. FEMS Microbiol Lett 217:15-22. http://dx.doi. org/1 0. 111 1 / j. 1 5 7 4-6968.2002.tb11450.x.
    • (2002) FEMS Microbiol Lett , vol.217 , pp. 15-22
    • Sabathé, F.1    Bélaïch, A.2    Soucaille, P.3
  • 69
    • 0036282456 scopus 로고    scopus 로고
    • Northern, morphological, and fermentation analysis of spo0A inactivation and overexpression in Clostridium acetobutylicum ATCC 824
    • Harris LM, Welker NE, Papoutsakis ET. 2002. Northern, morphological, and fermentation analysis of spo0A inactivation and overexpression in Clostridium acetobutylicum ATCC 824. J Bacteriol 184:3586-3597. http:// dx.doi.org/10.1128/JB.184.13.3586-3597.2002.
    • (2002) J Bacteriol , vol.184 , pp. 3586-3597
    • Harris, L.M.1    Welker, N.E.2    Papoutsakis, E.T.3
  • 71
    • 0036208358 scopus 로고    scopus 로고
    • Control of butanol formation in Clostridium acetobutylicum by transcriptional activation
    • Thormann K, Feustel L, Lorenz K, Nakotte S, Durre P. 2002. Control of butanol formation in Clostridium acetobutylicum by transcriptional activation. J Bacteriol 184:1966-1973. http://dx.doi.org/10.1128/ JB.184.7.1966-1973.2002.
    • (2002) J Bacteriol , vol.184 , pp. 1966-1973
    • Thormann, K.1    Feustel, L.2    Lorenz, K.3    Nakotte, S.4    Durre, P.5
  • 72
    • 1642396325 scopus 로고    scopus 로고
    • Transcriptional analysis of butanol stress and tolerance in Clostridium acetobutylicum
    • Tomas CA, Beamish J, Papoutsakis ET. 2004. Transcriptional analysis of butanol stress and tolerance in Clostridium acetobutylicum. J Bacteriol 186:2006-2018. http://dx.doi.org/10.1128/JB.186.7.2006-2018.2004.
    • (2004) J Bacteriol , vol.186 , pp. 2006-2018
    • Tomas, C.A.1    Beamish, J.2    Papoutsakis, E.T.3
  • 73
    • 84870868614 scopus 로고    scopus 로고
    • Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: Insights into the substrate specificity and the catalytic mechanism
    • Hu K, Zhao M, Zhang T, Zha M, Zhong C, Jiang Y, Ding J. 2013. Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism. Biochem J 449:79-89. http://dx.doi.org/ 10.1042/BJ20120871.
    • (2013) Biochem J , vol.449 , pp. 79-89
    • Hu, K.1    Zhao, M.2    Zhang, T.3    Zha, M.4    Zhong, C.5    Jiang, Y.6    Ding, J.7
  • 74
    • 0043044779 scopus 로고    scopus 로고
    • The glyceraldehyde-3-phosphate dehydrogenase of Clostridium acetobutylicum: Isolation and purification of the enzyme, and sequencing and localization of the gap gene within a cluster of other glycolytic genes
    • Schreiber W, Durre P. 1999. The glyceraldehyde-3-phosphate dehydrogenase of Clostridium acetobutylicum: isolation and purification of the enzyme, and sequencing and localization of the gap gene within a cluster of other glycolytic genes. Microbiology 145:1839-1847. http://dx.doi.org/ 10.1099/13500872-145-8-1839.
    • (1999) Microbiology , vol.145 , pp. 1839-1847
    • Schreiber, W.1    Durre, P.2
  • 75
    • 0036409043 scopus 로고    scopus 로고
    • Expression, purification, and characterization of recombinant nonphosphorylating NADPdependent glyceraldehyde-3-phosphate dehydrogenase from Clostridium acetobutylicum
    • Iddar A, Valverde F, Serrano A, Soukri A. 2002. Expression, purification, and characterization of recombinant nonphosphorylating NADPdependent glyceraldehyde-3-phosphate dehydrogenase from Clostridium acetobutylicum. Protein Expr Purif 25:519-526. http://dx.doi.org/ 10.1016/S1046-5928(02)00032-3.
    • (2002) Protein Expr Purif , vol.25 , pp. 519-526
    • Iddar, A.1    Valverde, F.2    Serrano, A.3    Soukri, A.4
  • 76
    • 84907920598 scopus 로고    scopus 로고
    • Parallel labeling experiments validate Clostridium acetobutylicum metabolic network model for C metabolic flux analysis
    • Au J, Choi J, Jones SW, Venkataramanan KP, Antoniewicz MR. 2014. Parallel labeling experiments validate Clostridium acetobutylicum metabolic network model for C metabolic flux analysis. Metab Eng 26:23-33. http://dx.doi.org/10.1016/j.ymben.2014.08.002.
    • (2014) Metab Eng , vol.26 , pp. 23-33
    • Au, J.1    Choi, J.2    Jones, S.W.3    Venkataramanan, K.P.4    Antoniewicz, M.R.5
  • 77
    • 0022066470 scopus 로고
    • The effect of pH on nitrogen supply, cell lysis, and solvent production in fermentations of Clostridium acetobutylicum
    • Roos JW, McLaughlin JK, Papoutsakis ET. 1985. The effect of pH on nitrogen supply, cell lysis, and solvent production in fermentations of Clostridium acetobutylicum. Biotechnol Bioeng 27:681-694. http:// dx.doi.org/10.1002/bit.260270518.
    • (1985) Biotechnol Bioeng , vol.27 , pp. 681-694
    • Roos, J.W.1    McLaughlin, J.K.2    Papoutsakis, E.T.3
  • 78
    • 33846464622 scopus 로고    scopus 로고
    • A standard operating procedure (SOP) for the preparation of intra-and extracellular proteins of Clostridium acetobutylicum for proteome analysis
    • Schwarz K, Fiedler T, Fischer R, Bahl H. 2007. A standard operating procedure (SOP) for the preparation of intra-and extracellular proteins of Clostridium acetobutylicum for proteome analysis. J Microbiol Methods 68:396-402. http://dx.doi.org/10.1016/j.mimet.2006.09.018.
    • (2007) J Microbiol Methods , vol.68 , pp. 396-402
    • Schwarz, K.1    Fiedler, T.2    Fischer, R.3    Bahl, H.4
  • 79
    • 0020669405 scopus 로고
    • Determination of total protein
    • Peterson GL. 1983. Determination of total protein. Methods Enzymol 91:95-119.
    • (1983) Methods Enzymol , vol.91 , pp. 95-119
    • Peterson, G.L.1
  • 80
    • 0003037055 scopus 로고
    • Chemical composition
    • In Gerhardt P, Murray RGE, Costilow RN, Nester EW, Wood WA, Krieg NR, Phillips GB (ed), American Society for Microbiology, Washington, DC
    • Hanson R, Phillips J. 1981. Chemical composition, p 328-364. In Gerhardt P, Murray RGE, Costilow RN, Nester EW, Wood WA, Krieg NR, Phillips GB (ed), Manual of methods for general bacteriology. American Society for Microbiology, Washington, DC.
    • (1981) Manual of methods for general bacteriology , pp. 328-364
    • Hanson, R.1    Phillips, J.2
  • 81
    • 0022694453 scopus 로고
    • Acetonobutylic fermentation: Improvement of performances by coupling continuous fermentation and ultrafiltration
    • Ferras E, Minier M, Goma G. 1986. Acetonobutylic fermentation: improvement of performances by coupling continuous fermentation and ultrafiltration. Biotechnol Bioeng 28:523-533. http://dx.doi.org/10.1002/ bit.260280408.
    • (1986) Biotechnol Bioeng , vol.28 , pp. 523-533
    • Ferras, E.1    Minier, M.2    Goma, G.3
  • 82
    • 84876863362 scopus 로고    scopus 로고
    • Metabolic engineering of Clostridium acetobutylicum ATCC 824 for the high-yield production of a biofuel composed of an isopropanol/butanol/ethanol mixture
    • Dusséaux S, Croux C, Soucaille P, Meynial-Salles I. 2013. Metabolic engineering of Clostridium acetobutylicum ATCC 824 for the high-yield production of a biofuel composed of an isopropanol/butanol/ethanol mixture. Metab Eng 18:1-8. http://dx.doi.org/10.1016/j.ymben.2013.03.003.
    • (2013) Metab Eng , vol.18 , pp. 1-8
    • Dusséaux, S.1    Croux, C.2    Soucaille, P.3    Meynial-Salles, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.