-
1
-
-
84890107642
-
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
-
Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Dec
-
Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat Biotechnol 2013 Dec;31(12):1102–1110.
-
(2013)
Nat Biotechnol
, vol.31
, Issue.12
, pp. 1102-1110
-
-
Denny, J.C.1
Bastarache, L.2
Ritchie, M.D.3
-
2
-
-
84928175264
-
Expanding the mutation spectrum affecting αIIbβ3 integrin in Glanzmann thrombasthenia: screening of the ITGA2B and ITGB3 genes in a large international cohort
-
Alessi MC, Bonduel M, Dreyfus M, Goudemand J, Gruel Y, Benabdallah-Guerida S, Latger-Cannard V, May
-
Nurden AT, Pillois X, Fiore M, Alessi MC, Bonduel M, Dreyfus M, Goudemand J, Gruel Y, Benabdallah-Guerida S, Latger-Cannard V, et al. Expanding the mutation spectrum affecting αIIbβ3 integrin in Glanzmann thrombasthenia:screening of the ITGA2B and ITGB3 genes in a large international cohort. Hum Mutat 2015 May;36(5):548–561.
-
(2015)
Hum Mutat
, vol.36
, Issue.5
, pp. 548-561
-
-
Nurden, A.T.1
Pillois, X.2
Fiore, M.3
-
3
-
-
84892845161
-
Human platelet antigens - 2013
-
Feb
-
Curtis BR, McFarland JG., Human platelet antigens - 2013. Vox Sang 2014 Feb;106(2):93–102.
-
(2014)
Vox Sang
, vol.106
, Issue.2
, pp. 93-102
-
-
Curtis, B.R.1
McFarland, J.G.2
-
4
-
-
85009776893
-
-
Uhrynowska M, Guz K, Orzińska A, Dębski R, Maślanka K., Nov 12. [Epub ahead of print] PubMed PMID: 26564154
-
Brojer E, Husebekk A, Dębska M, Uhrynowska M, Guz K, Orzińska A, Dębski R, Maślanka K. Fetal/Neonatal alloimmune thrombocytopenia:pathogenesis, diagnostics and prevention. Arch Immunol Ther Exp (Warsz) 2015 Nov 12. [Epub ahead of print] PubMed PMID:26564154.
-
(2015)
Fetal/Neonatal alloimmune thrombocytopenia: pathogenesis, diagnostics and prevention. Arch Immunol Ther Exp (Warsz)
-
-
Brojer, E.1
Husebekk, A.2
Dębska, M.3
-
5
-
-
84946849847
-
Advances in alloimmune thrombocytopenia: perspectives on current concepts of human platelet antigens, antibody detection strategies, and genotyping
-
Jul
-
Hayashi T, Hirayama F., Advances in alloimmune thrombocytopenia:perspectives on current concepts of human platelet antigens, antibody detection strategies, and genotyping. Blood Transfus 2015 Jul;13(3):380–390.
-
(2015)
Blood Transfus
, vol.13
, Issue.3
, pp. 380-390
-
-
Hayashi, T.1
Hirayama, F.2
-
7
-
-
79955631083
-
Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease
-
Greisenegger S, Marsik C, Wagner OF, Endler G
-
Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, Endler G. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arterioscler Thromb Vasc Biol 2011;31:1215–1218.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1215-1218
-
-
Slavka, G.1
Perkmann, T.2
Haslacher, H.3
-
8
-
-
38949103390
-
Common risk factors for both arterial and venous thrombosis
-
Lowe GDO., Common risk factors for both arterial and venous thrombosis. Br J Haematol 2008;140:488–495.
-
(2008)
Br J Haematol
, vol.140
, pp. 488-495
-
-
Lowe, G.D.O.1
-
9
-
-
73049084524
-
Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study
-
Braekken SK, Mathiesen EB, Njolstad I, et al. Mean platelet volume is a risk factor for venous thromboembolism:the Tromsø study. J Thromb Haemost 2010;8:157–162.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 157-162
-
-
Braekken, S.K.1
Mathiesen, E.B.2
Njolstad, I.3
-
10
-
-
77949652459
-
Mean platelet volume predicts early death in acute pulmonary embolism
-
Hrynkiewicz-Szymańska A, Pacho S, Jankowski K, Lichodziejewska B, Pruszczyk P
-
Kostrubiec M, Labyk A, Pedowska-Wloszek J, Hrynkiewicz-Szymańska A, Pacho S, Jankowski K, Lichodziejewska B, Pruszczyk P. Mean platelet volume predicts early death in acute pulmonary embolism. Heart 2010;96:460–465.
-
(2010)
Heart
, vol.96
, pp. 460-465
-
-
Kostrubiec, M.1
Labyk, A.2
Pedowska-Wloszek, J.3
-
11
-
-
84983184245
-
Prognostic effect of mean platelet volume in patients with coronary artery disease: a systematic review and meta-analysis
-
Sansanayudh N, Numthavaj P, Muntham D, Yamwong S, McEvoy M, Attia J, Sritara P, Thakkinstian A., Prognostic effect of mean platelet volume in patients with coronary artery disease:a systematic review and meta-analysis. Thromb Haemost 2015;114(6):1299–1309.
-
(2015)
Thromb Haemost
, vol.114
, Issue.6
, pp. 1299-1309
-
-
Sansanayudh, N.1
Numthavaj, P.2
Muntham, D.3
Yamwong, S.4
McEvoy, M.5
Attia, J.6
Sritara, P.7
Thakkinstian, A.8
-
12
-
-
1442274814
-
PROGRESS Collaborative Group
-
Mar, Epub 2004 Feb 19
-
Bath P, Algert C, Chapman N, Neal B,; PROGRESS Collaborative Group. Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke 2004 Mar;35(3):622–626. Epub 2004 Feb 19.
-
(2004)
Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke
, vol.35
, Issue.3
, pp. 622-626
-
-
Bath, P.1
Algert, C.2
Chapman, N.3
Neal, B.4
-
13
-
-
83655167183
-
Mean platelet volume and integrin alleles correlate with levels of integrins [alpha]IIb[beta]3 and [alpha]2[beta]1 in acute coronary syndrome patients and normal subjects
-
Kunicki TJ, Williams SA, Nugent DJ, Yeager M., Mean platelet volume and integrin alleles correlate with levels of integrins [alpha]IIb[beta]3 and [alpha]2[beta]1 in acute coronary syndrome patients and normal subjects. Arterioscler Thromb Vasc Biol 2011;32:147–152.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 147-152
-
-
Kunicki, T.J.1
Williams, S.A.2
Nugent, D.J.3
Yeager, M.4
-
14
-
-
84894090437
-
Relationships of glycoproteins IIb-IIIa and Ib content with mean platelet volume and their genetic polymorphisms
-
Mar
-
Khaspekova SG, Zyuryaev IT, Yakushkin VV, Sirotkina OV, Zaytseva NO, Ruda MY, Panteleev MA, Mazurov AV., Relationships of glycoproteins IIb-IIIa and Ib content with mean platelet volume and their genetic polymorphisms. Blood Coagul Fibrinolysis 2014 Mar;25(2):128–134.
-
(2014)
Blood Coagul Fibrinolysis
, vol.25
, Issue.2
, pp. 128-134
-
-
Khaspekova, S.G.1
Zyuryaev, I.T.2
Yakushkin, V.V.3
Sirotkina, O.V.4
Zaytseva, N.O.5
Ruda, M.Y.6
Panteleev, M.A.7
Mazurov, A.V.8
-
15
-
-
79956027695
-
Glycoprotein IIb-IIIa content and platelet aggregation in healthy volunteers and patients with acute coronary syndrome
-
Sirotkina OV, Zaytseva NO, Ruda MY, Panteleev MA, Mazurov AV
-
Yakushkin VV, Zyuryaev IT, Khaspekova SG, Sirotkina OV, Zaytseva NO, Ruda MY, Panteleev MA, Mazurov AV. Glycoprotein IIb-IIIa content and platelet aggregation in healthy volunteers and patients with acute coronary syndrome. Platelets 2011;22:243–251.
-
(2011)
Platelets
, vol.22
, pp. 243-251
-
-
Yakushkin, V.V.1
Zyuryaev, I.T.2
Khaspekova, S.G.3
-
16
-
-
35648984592
-
Effects of platelet glycoprotein IIb-IIIa number and glycoprotein IIIa Leu33Pro polymorphism on platelet aggregation and sensitivity to glycoprotein IIb-IIIa antagonists
-
Shimanova YV, Mazurov AV
-
Sirotkina OV, Khaspekova SG, Zabotina AM, Shimanova YV, Mazurov AV. Effects of platelet glycoprotein IIb-IIIa number and glycoprotein IIIa Leu33Pro polymorphism on platelet aggregation and sensitivity to glycoprotein IIb-IIIa antagonists. Platelets 2007;18:506–514.
-
(2007)
Platelets
, vol.18
, pp. 506-514
-
-
Sirotkina, O.V.1
Khaspekova, S.G.2
Zabotina, A.M.3
-
17
-
-
22044443870
-
Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention
-
Horszczaruk GJ, Grabowski M, Piatkowski R, Wilczynska J, Zielinski A, Meier B, Opolski G
-
Huczek Z, Kochman J, Filipiak KJ, Horszczaruk GJ, Grabowski M, Piatkowski R, Wilczynska J, Zielinski A, Meier B, Opolski G. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. J Am Coll Cardiol 2005;46:284–290.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 284-290
-
-
Huczek, Z.1
Kochman, J.2
Filipiak, K.J.3
-
19
-
-
48549092701
-
Role of mean platelet volume in triagging acute coronary syndromes
-
Guray U, Kisacik HL, Sasmaz H, Korkmaz S
-
Yilmaz MB, Cihan G, Guray Y, Guray U, Kisacik HL, Sasmaz H, Korkmaz S. Role of mean platelet volume in triagging acute coronary syndromes. J Thromb Thrombolysis 2008;26:49–54.
-
(2008)
J Thromb Thrombolysis
, vol.26
, pp. 49-54
-
-
Yilmaz, M.B.1
Cihan, G.2
Guray, Y.3
-
20
-
-
2942717114
-
Influence of haematological parameters before coronary angioplasty on subsequent restenosis
-
Cosgun A, Gokce V, Duru E, Korkmaz S
-
Avci A, Boyaci A, Cagli K, Cosgun A, Gokce V, Duru E, Korkmaz S. Influence of haematological parameters before coronary angioplasty on subsequent restenosis. Acta Cardiol 2004;59:263–268.
-
(2004)
Acta Cardiol
, vol.59
, pp. 263-268
-
-
Avci, A.1
Boyaci, A.2
Cagli, K.3
-
21
-
-
79955631083
-
Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease
-
Greisenegger S, Marsik C, Wagner OF, Endler G
-
Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, Endler G. Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease. Arterioscler Thromb Vasc Biol 2011;31:1215–1218.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1215-1218
-
-
Slavka, G.1
Perkmann, T.2
Haslacher, H.3
-
22
-
-
78650936225
-
High platelet volume and increased risk of myocardial infarction: 39 531 participants from the general population
-
Klovaite J, Benn M, Yazdanyar S, Nordestgaard BG., High platelet volume and increased risk of myocardial infarction:39 531 participants from the general population. J Thromb Haemost 2011;9:49–56.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 49-56
-
-
Klovaite, J.1
Benn, M.2
Yazdanyar, S.3
Nordestgaard, B.G.4
-
23
-
-
72649106813
-
Prognostic role of mean platelet volume and platelet count in ischemic and hemorrhagic stroke
-
Mayda-Domaç F, Misirli H, Yilmaz M., Prognostic role of mean platelet volume and platelet count in ischemic and hemorrhagic stroke. J Stroke Cerebrovasc Dis 2010;19:66–72.
-
(2010)
J Stroke Cerebrovasc Dis
, vol.19
, pp. 66-72
-
-
Mayda-Domaç, F.1
Misirli, H.2
Yilmaz, M.3
-
24
-
-
0031788476
-
The relationship between mean platelet volume, stroke subtype and clinical outcome
-
Butterworth RJ, Bath PM., The relationship between mean platelet volume, stroke subtype and clinical outcome. Platelets 1998;9:359–364.
-
(1998)
Platelets
, vol.9
, pp. 359-364
-
-
Butterworth, R.J.1
Bath, P.M.2
-
25
-
-
38949103390
-
Common risk factors for both arterial and venous thrombosis
-
Lowe GDO., Common risk factors for both arterial and venous thrombosis. Br J Haematol 2008; 140:488–495.
-
(2008)
Br J Haematol
, vol.140
, pp. 488-495
-
-
Lowe, G.D.O.1
-
26
-
-
73049108488
-
Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis
-
Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, Mohler ER, Reilly MP, Berger JS., Mean platelet volume as a predictor of cardiovascular risk:a systematic review and meta-analysis. J Thromb Haemost 2010;8:148–156.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 148-156
-
-
Chu, S.G.1
Becker, R.C.2
Berger, P.B.3
Bhatt, D.L.4
Eikelboom, J.W.5
Konkle, B.6
Mohler, E.R.7
Reilly, M.P.8
Berger, J.S.9
-
27
-
-
84938418116
-
Genetic determinants of platelet large-cell ratio, immature platelet fraction, and other platelet-related phenotypes
-
Aug
-
Pujol-Moix N, Vázquez-Santiago M, Morera A, Ziyatdinov A, Remacha A, Nomdedeu JF, Fontcuberta J, Soria JM, Souto JC., Genetic determinants of platelet large-cell ratio, immature platelet fraction, and other platelet-related phenotypes. Thromb Res 2015 Aug;136(2):361–366.
-
(2015)
Thromb Res
, vol.136
, Issue.2
, pp. 361-366
-
-
Pujol-Moix, N.1
Vázquez-Santiago, M.2
Morera, A.3
Ziyatdinov, A.4
Remacha, A.5
Nomdedeu, J.F.6
Fontcuberta, J.7
Soria, J.M.8
Souto, J.C.9
-
28
-
-
73049084524
-
Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study
-
Wilsgaard T, Størmer J, Hansen JB
-
Braekken SK, Mathiesen EB, Njolstad I, Wilsgaard T, Størmer J, Hansen JB. Mean platelet volume is a risk factor for venous thromboembolism:the Tromsø study. J Thromb Haemost 2010;8:157–162.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 157-162
-
-
Braekken, S.K.1
Mathiesen, E.B.2
Njolstad, I.3
-
29
-
-
77949652459
-
Mean platelet volume predicts early death in acute pulmonary embolism
-
Hrynkiewicz-Szymańska A, Pacho S, Jankowski K, Lichodziejewska B, Pruszczyk P
-
Kostrubiec M, Labyk A, Pedowska-Wloszek J, Hrynkiewicz-Szymańska A, Pacho S, Jankowski K, Lichodziejewska B, Pruszczyk P. Mean platelet volume predicts early death in acute pulmonary embolism. Heart 2010;96:460–465.
-
(2010)
Heart
, vol.96
, pp. 460-465
-
-
Kostrubiec, M.1
Labyk, A.2
Pedowska-Wloszek, J.3
-
30
-
-
42549093946
-
The effects of coronary artery disease severity on time-dependent changes in platelet activation indices in stored whole blood
-
Boos CJ, Balakrishnan B, Lip GYH., The effects of coronary artery disease severity on time-dependent changes in platelet activation indices in stored whole blood. J Thromb Thrombolysis 2008;25:135–140.
-
(2008)
J Thromb Thrombolysis
, vol.25
, pp. 135-140
-
-
Boos, C.J.1
Balakrishnan, B.2
Lip, G.Y.H.3
-
31
-
-
84860227260
-
Mean platelet volume: comparison of three analysers towards standardization of platelet morphological phenotype
-
Baumgart D, Nurden P, Lecompte T
-
Latger-Cannard V, Hoarau M, Salignac S, Baumgart D, Nurden P, Lecompte T. Mean platelet volume:comparison of three analysers towards standardization of platelet morphological phenotype. Int J Lab Hematol 2012;34:300–310.
-
(2012)
Int J Lab Hematol
, vol.34
, pp. 300-310
-
-
Latger-Cannard, V.1
Hoarau, M.2
Salignac, S.3
-
32
-
-
84865777825
-
Linking disease associations with regulatory information in the human genome
-
Schaub MA, Boyle AP, Kundaje A, Batzoglou S, Snyder M., Linking disease associations with regulatory information in the human genome. Genome Res 2012;22:1748–1759.
-
(2012)
Genome Res
, vol.22
, pp. 1748-1759
-
-
Schaub, M.A.1
Boyle, A.P.2
Kundaje, A.3
Batzoglou, S.4
Snyder, M.5
-
33
-
-
83055161438
-
New gene functions in megakaryopoiesis and platelet formation
-
Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y
-
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, et al. New gene functions in megakaryopoiesis and platelet formation. Nature 2011;480:201–208.
-
(2011)
Nature
, vol.480
, pp. 201-208
-
-
Gieger, C.1
Radhakrishnan, A.2
Cvejic, A.3
-
34
-
-
84859224216
-
A meta-analysis and genome-wide association study of platelet count and mean platelet volume in African Americans
-
Nalls MA, Liu Y, Tang W, Yanek LR, Lange L, Evans MK, Ganesh S
-
Qayyum R, Snively BM, Ziv E, Nalls MA, Liu Y, Tang W, Yanek LR, Lange L, Evans MK, Ganesh S, et al. A meta-analysis and genome-wide association study of platelet count and mean platelet volume in African Americans. PLoS Genet 2012;8:e1002491.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002491
-
-
Qayyum, R.1
Snively, B.M.2
Ziv, E.3
-
35
-
-
79953756857
-
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
-
Folsom AR, Galarneau G, Ganesh SK, Grant SF, Keating BJ, McCarroll SA, Mohler ER 3rd, et al
-
Lo KS, Wilson JG, Lange LA, Folsom AR, Galarneau G, Ganesh SK, Grant SF, Keating BJ, McCarroll SA, Mohler ER 3rd, et al. Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. Hum Genet 2011;129:307–317.
-
(2011)
Hum Genet
, vol.129
, pp. 307-317
-
-
Lo, K.S.1
Wilson, J.G.2
Lange, L.A.3
-
36
-
-
84957838060
-
Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans
-
Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, et al
-
Schick UM, Jain D, Hodonsky CJ, Morrison JV, Davis JP, Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, et al. Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. Am J Hum Genet 2016;98(2):229–242.
-
(2016)
Am J Hum Genet
, vol.98
, Issue.2
, pp. 229-242
-
-
Schick, U.M.1
Jain, D.2
Hodonsky, C.J.3
Morrison, J.V.4
Davis, J.P.5
-
37
-
-
46249103285
-
Polymorphisms in platelet glycoprotein 1bα and factor VII and risk of ischemic stroke: a meta-analysis
-
Levi C, Lincz L, Parsons M, Whyte S, Attia J
-
Maguire JM, Thakkinstian A, Sturm J, Levi C, Lincz L, Parsons M, Whyte S, Attia J. Polymorphisms in platelet glycoprotein 1bα and factor VII and risk of ischemic stroke:a meta-analysis. Stroke 2008;39:1710–1716.
-
(2008)
Stroke
, vol.39
, pp. 1710-1716
-
-
Maguire, J.M.1
Thakkinstian, A.2
Sturm, J.3
-
38
-
-
84905455420
-
A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis
-
7, eCollection 2014 Jul
-
Bielczyk-Maczyńska E, Serbanovic-Canic J, Ferreira L, Soranzo N, Stemple DL, Ouwehand WH, Cvejic A., A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis. PLoS Genet 2014;10(7):e1004450. doi:10.1371/journal.pgen.1004450. eCollection 2014 Jul.
-
(2014)
PLoS Genet
, vol.10
, pp. e1004450
-
-
Bielczyk-Maczyńska, E.1
Serbanovic-Canic, J.2
Ferreira, L.3
Soranzo, N.4
Stemple, D.L.5
Ouwehand, W.H.6
Cvejic, A.7
-
39
-
-
84891858260
-
A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects
-
Jan
-
Shameer K, Denny JC, Ding K, Jouni H, Crosslin DR, de Andrade M, Chute CG, Peissig P, Pacheco JA, Li R, et al. A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. Hum Genet 2014 Jan;133(1):95–109.
-
(2014)
Hum Genet
, vol.133
, Issue.1
, pp. 95-109
-
-
-
40
-
-
84964687940
-
Integrative multi-omic analysis of human platelet eQTLs reveals alternative start site in Mitofusin 2
-
May 5
-
Simon LM, Chen ES, Edelstein LC, Kong X, Bhatlekar S, Rigoutsos I, Bray PF, Shaw CA., Integrative multi-omic analysis of human platelet eQTLs reveals alternative start site in Mitofusin 2. Am J Hum Genet 2016 May 5;98(5):883–897.
-
(2016)
Am J Hum Genet
, vol.98
, Issue.5
, pp. 883-897
-
-
Simon, L.M.1
Chen, E.S.2
Edelstein, L.C.3
Kong, X.4
Bhatlekar, S.5
Rigoutsos, I.6
Bray, P.F.7
Shaw, C.A.8
-
41
-
-
83655167183
-
Mean platelet volume and integrin alleles correlate with levels of integrins αIIbβ3 and α2β1 in acute coronary syndrome patients and normal subjects
-
Kunicki TJ, Williams SA, Nugent DJ, Yeager M., Mean platelet volume and integrin alleles correlate with levels of integrins αIIbβ3 and α2β1 in acute coronary syndrome patients and normal subjects. Arterioscler Thromb Vasc Biol 2011;32:147–152.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 147-152
-
-
Kunicki, T.J.1
Williams, S.A.2
Nugent, D.J.3
Yeager, M.4
-
42
-
-
83055161438
-
New gene functions in megakaryopoiesis and platelet formation
-
Gieger C, Radhakrishnan A, Cvejic A, et al. New gene functions in megakaryopoiesis and platelet formation. Nature 2011; 480:201–208.
-
(2011)
Nature
, vol.480
, pp. 201-208
-
-
-
43
-
-
77949534952
-
Bone marrow osteoblastic niche: a new model to study physiological regulation of megakaryopoiesis
-
Pallotta I, Lovett M, Rice W, Kaplan DL, Balduini A. Bone marrow osteoblastic niche:a new model to study physiological regulation of megakaryopoiesis. PLoS One 2009;4:e8359.
-
(2009)
PLoS One
, vol.4
, pp. e8359
-
-
Pallotta, I.1
Lovett, M.2
Rice, W.3
-
44
-
-
33745609531
-
Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment
-
Franc B, Charrier S, Jandrot-Perrus M, Farndale RW, Jalil A, Blundell MP, Cramer EM, et al
-
Sabri S, Foudi A, Boukour S, Franc B, Charrier S, Jandrot-Perrus M, Farndale RW, Jalil A, Blundell MP, Cramer EM, et al. Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment. Blood 2006;108:134–140.
-
(2006)
Blood
, vol.108
, pp. 134-140
-
-
Sabri, S.1
Foudi, A.2
Boukour, S.3
-
45
-
-
79959279291
-
Mutations in ANKRD26 are responsible for a frequent form of inherited thrombocytopenia: analysis of 78 patients from 21 families
-
Noris P, Perrotta S, Seri M, Pecci A, Gnan C, Loffredo G, Pujol-Moix N, Zecca M, Scognamiglio F, De Rocco D, et al. Mutations in ANKRD26 are responsible for a frequent form of inherited thrombocytopenia:analysis of 78 patients from 21 families. Blood 2011;117:6673–6680.
-
(2011)
Blood
, vol.117
, pp. 6673-6680
-
-
Noris, P.1
Perrotta, S.2
Seri, M.3
-
46
-
-
0031456787
-
Interdonor variability of platelet response to thrombin receptor activation: influence of PIA2 polymorphism
-
Lasne D, Krenn M, Pingault V, Arnaud E, Fiessinger JN, Aiach M, Rendu F. Interdonor variability of platelet response to thrombin receptor activation:influence of PIA2 polymorphism. Br J Haematol 1997;99:801–807.
-
(1997)
Br J Haematol
, vol.99
, pp. 801-807
-
-
Lasne, D.1
Krenn, M.2
Pingault, V.3
-
47
-
-
0033135674
-
Increased binding of fibrinogen to glycoprotein IIIa-proline33 (HPA-1b, PlA2, Zwb) positive platelets in patients with cardiovascular disease
-
Hurd C, Knight CJ, Ouwehand WH, Fox KM
-
Goodall AH, Curzen N, Panesar M, Hurd C, Knight CJ, Ouwehand WH, Fox KM. Increased binding of fibrinogen to glycoprotein IIIa-proline33 (HPA-1b, PlA2, Zwb) positive platelets in patients with cardiovascular disease. Eur Heart J 1999;20:742–747.
-
(1999)
Eur Heart J
, vol.20
, pp. 742-747
-
-
Goodall, A.H.1
Curzen, N.2
Panesar, M.3
-
48
-
-
18244414272
-
Platelet GP IIIa PI(A) polymorphisms display different sensitivities to agonists
-
Mascelli MA, Hendrix C, Coleman L, Hamlington J, Barnard MR, Kickler T, Christie DJ, et al
-
Michelson AD, Furman MI, Goldschmidt-Clermont P, Mascelli MA, Hendrix C, Coleman L, Hamlington J, Barnard MR, Kickler T, Christie DJ, et al. Platelet GP IIIa PI(A) polymorphisms display different sensitivities to agonists. Circulation 2000;101:1013–1018.
-
(2000)
Circulation
, vol.101
, pp. 1013-1018
-
-
Michelson, A.D.1
Furman, M.I.2
Goldschmidt-Clermont, P.3
-
49
-
-
0034889515
-
The effect of human platelet alloantigen polymorphisms on the in vitro responsiveness to adrenaline and collagen
-
Dimitriadou E, Economopoulos P, Loucopoulos D
-
Theodoropoulos I, Christopoulos C, Metcalfe P, Dimitriadou E, Economopoulos P, Loucopoulos D. The effect of human platelet alloantigen polymorphisms on the in vitro responsiveness to adrenaline and collagen. Br J Haematol 2001;114:387–393.
-
(2001)
Br J Haematol
, vol.114
, pp. 387-393
-
-
Theodoropoulos, I.1
Christopoulos, C.2
Metcalfe, P.3
-
50
-
-
33744976086
-
Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3
-
Vijayan KV, Bray PF., Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes:Enhanced outside-in signaling through the Pro33 variant of integrin beta3. Exp Biol Med (Maywood) 2006;231:505–513.
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, pp. 505-513
-
-
Vijayan, K.V.1
Bray, P.F.2
-
51
-
-
0030942489
-
Hereditary variation in platelet integrin alpha2beta1 copy number is associated with two silent polymorphisms in the alpha2 gene coding sequence
-
Kunicki TJ, Kritzik M, Annis DS, Nugent DJ., Hereditary variation in platelet integrin alpha2beta1 copy number is associated with two silent polymorphisms in the alpha2 gene coding sequence. Blood 1997;89:1939–1943.
-
(1997)
Blood
, vol.89
, pp. 1939-1943
-
-
Kunicki, T.J.1
Kritzik, M.2
Annis, D.S.3
Nugent, D.J.4
-
52
-
-
23244440000
-
Association of the -92C/G and 807C/T polymorphisms of the alpha2 subunit gene with human platelets alpha2beta1 receptor density
-
Grandchamp B, Ducellier P, Huart V, Verpillat P, Guillin MC, Benessiano J
-
Ajzenberg N, Berroeta C, Philip I, Grandchamp B, Ducellier P, Huart V, Verpillat P, Guillin MC, Benessiano J. Association of the -92C/G and 807C/T polymorphisms of the alpha2 subunit gene with human platelets alpha2beta1 receptor density. Arterioscler Thromb Vasc Biol 2005;25:1756–1760.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1756-1760
-
-
Ajzenberg, N.1
Berroeta, C.2
Philip, I.3
-
53
-
-
0038819123
-
The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression
-
Gray E, IJsseldijk M, Onley CM, Watkins NA, Williamson LM, Goodall AH, de Groot PG, et al
-
Joutsi-Korhonen L, Smethurst PA, Rankin A, Gray E, IJsseldijk M, Onley CM, Watkins NA, Williamson LM, Goodall AH, de Groot PG, et al. The low-frequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression. Blood 2003;101:4372–4379.
-
(2003)
Blood
, vol.101
, pp. 4372-4379
-
-
Joutsi-Korhonen, L.1
Smethurst, P.A.2
Rankin, A.3
-
54
-
-
70349249996
-
The low-frequency isoform of platelet glycoprotein VIb attenuates ligand-mediated signal transduction but not receptor expression or ligand binding
-
Furihata K, Pulcinelli FM, Nugent DJ, Kunicki TJ
-
Trifiro E, Williams SA, Cheli Y, Furihata K, Pulcinelli FM, Nugent DJ, Kunicki TJ. The low-frequency isoform of platelet glycoprotein VIb attenuates ligand-mediated signal transduction but not receptor expression or ligand binding. Blood 2009;114:1893–1899.
-
(2009)
Blood
, vol.114
, pp. 1893-1899
-
-
Trifiro, E.1
Williams, S.A.2
Cheli, Y.3
-
55
-
-
0026655919
-
Polymorphism of human glycoprotein Ib-alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region
-
Lopez JA, Ludwig EH, McCarthy BJ., Polymorphism of human glycoprotein Ib-alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. J Biol Chem 1992;267:10055–10061.
-
(1992)
J Biol Chem
, vol.267
, pp. 10055-10061
-
-
Lopez, J.A.1
Ludwig, E.H.2
McCarthy, B.J.3
-
56
-
-
0029088691
-
The largest variant of platelet glycoprotein Ib++_has four tandem repeats of 13 amino acids in the macroglycopeptide region and a genetic linkage with Methionine 145
-
Yan J, Kitano K, Kiyosawa K, Furuta S
-
Ishida F, Furihata K, Ishida K, Yan J, Kitano K, Kiyosawa K, Furuta S. The largest variant of platelet glycoprotein Ib++_has four tandem repeats of 13 amino acids in the macroglycopeptide region and a genetic linkage with Methionine 145. Blood 1995;86:1356–1360.
-
(1995)
Blood
, vol.86
, pp. 1356-1360
-
-
Ishida, F.1
Furihata, K.2
Ishida, K.3
-
57
-
-
0033168684
-
Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex
-
Afshar-Kharghan V, Li CQ, Khoshnevis-Asl M, Lopez JA., Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex. Blood 1999;94:186–191.
-
(1999)
Blood
, vol.94
, pp. 186-191
-
-
Afshar-Kharghan, V.1
Li, C.Q.2
Khoshnevis-Asl, M.3
Lopez, J.A.4
-
58
-
-
0026610362
-
NH2-Terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145 /threonine 145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens
-
Ouwehand WH, von dem Borne AE
-
Kuijpers RWAM, Faber NM, Cuypers HTM, Ouwehand WH, von dem Borne AE. NH2-Terminal globular domain of human platelet glycoprotein Ib alpha has a methionine 145 /threonine 145 amino acid polymorphism, which is associated with the HPA-2 (Ko) alloantigens. J Clin Invest 1992;89:381–384.
-
(1992)
J Clin Invest
, vol.89
, pp. 381-384
-
-
Kuijpers, R.W.A.M.1
Faber, N.M.2
Cuypers, H.T.M.3
-
59
-
-
0042859862
-
Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects
-
Bachelot-Loza C, Reny JL, Aiach M, Gaussem P
-
Fontana P, Dupont A, Gandrille S, Bachelot-Loza C, Reny JL, Aiach M, Gaussem P. Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects. Circulation 2003;108:989–995.
-
(2003)
Circulation
, vol.108
, pp. 989-995
-
-
Fontana, P.1
Dupont, A.2
Gandrille, S.3
-
60
-
-
0037369218
-
An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN
-
Reny JL, Biéche I, Desvard F, Aiach M, Gaussem P
-
Dupont A, Fontana P, Bachelot-Loza C, Reny JL, Biéche I, Desvard F, Aiach M, Gaussem P. An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN. Blood 2003;101:1833–1840.
-
(2003)
Blood
, vol.101
, pp. 1833-1840
-
-
Dupont, A.1
Fontana, P.2
Bachelot-Loza, C.3
-
61
-
-
11144232964
-
Dimorphism in the P2Y1 ADP receptor gene is associated with increased platelet activation response to ADP
-
Thompson JR, Goodall AH, Samani NJ
-
Hetherington SL, Singh RK, Lodwick D, Thompson JR, Goodall AH, Samani NJ. Dimorphism in the P2Y1 ADP receptor gene is associated with increased platelet activation response to ADP. Arterioscler Thromb Vasc Biol 2005;25:252–257.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 252-257
-
-
Hetherington, S.L.1
Singh, R.K.2
Lodwick, D.3
-
62
-
-
33748607448
-
Identification of functional polymorphisms of the thromboxane A2 receptor gene in healthy volunteers
-
Dupont A, Reny JL, Aiach M, Gaussem P
-
Fontana P, Gandrille S, Remones V, Dupont A, Reny JL, Aiach M, Gaussem P. Identification of functional polymorphisms of the thromboxane A2 receptor gene in healthy volunteers. Thromb Haemost 2006;96:356–360.
-
(2006)
Thromb Haemost
, vol.96
, pp. 356-360
-
-
Fontana, P.1
Gandrille, S.2
Remones, V.3
-
63
-
-
33746329904
-
Identification of ADRA2A polymorphisms related to shear-mediated platelet function
-
Ishihara H, Shibano T, Miyaki K, Omae K, Watanabe G, Murata M, Ikeda Y
-
Yabe M, Matsubara Y, Takahashi S, Ishihara H, Shibano T, Miyaki K, Omae K, Watanabe G, Murata M, Ikeda Y. Identification of ADRA2A polymorphisms related to shear-mediated platelet function. Biochem Biophys Res Commun 2006;347:1001–1005.
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 1001-1005
-
-
Yabe, M.1
Matsubara, Y.2
Takahashi, S.3
-
64
-
-
67849089161
-
A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways
-
Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, et al
-
Jones CI, Bray S, Garner SF, Stephens J, de Bono B, Angenent WG, Bentley D, Burns P, Coffey A, Deloukas P, et al. A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways. Blood 2009;114:1405–1416.
-
(2009)
Blood
, vol.114
, pp. 1405-1416
-
-
Jones, C.I.1
Bray, S.2
Garner, S.F.3
-
65
-
-
77954145555
-
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists
-
Johnson AD, Yanek LR, Chen M-H, Faraday N, Larson MG, Tofler G, Lin SJ, Kraja AT, Province MA, Yang Q, et al. Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. Nat Genet 2010;42:608–613.
-
(2010)
Nat Genet
, vol.42
, pp. 608-613
-
-
Johnson, A.D.1
Yanek, L.R.2
Chen, M.-H.3
-
66
-
-
33646812887
-
polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms
-
Watkins NA, O’Connor MN, Rankin A, Jennings N, Wilson E, Harmer IJ, Davies L, Smethurst PA, Dudbridge F, Farndale RW, Ouwehand WH. Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms. J Thromb Haemost 2006;4:1197–1205.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 1197-1205
-
-
-
67
-
-
80053187033
-
Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression
-
Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, et al
-
Faraday N, Yanek LR, Yang XP, Mathias R, Herrera-Galeano JE, Suktitipat B, Qayyum R, Johnson AD, Chen MH, Tofler GH, et al. Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. Blood 2011;118:3367–3375.
-
(2011)
Blood
, vol.118
, pp. 3367-3375
-
-
Faraday, N.1
Yanek, L.R.2
Yang, X.P.3
-
68
-
-
84930662804
-
Genome-wide association study of platelet aggregation in African Americans
-
Qayyum R, Becker LC, Becker DM, Faraday N, Yanek LR, Leal SM, Shaw C, Mathias R, Suktitipat B, Bray PF., Genome-wide association study of platelet aggregation in African Americans. BMC Genet 2015;16:58.
-
(2015)
BMC Genet
, vol.16
, pp. 58
-
-
Qayyum, R.1
Becker, L.C.2
Becker, D.M.3
Faraday, N.4
Yanek, L.R.5
Leal, S.M.6
Shaw, C.7
Mathias, R.8
Suktitipat, B.9
Bray, P.F.10
-
69
-
-
70350644759
-
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
-
Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, et al
-
Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet 2009;41:1182–1190.
-
(2009)
Nat Genet
, vol.41
, pp. 1182-1190
-
-
Soranzo, N.1
Spector, T.D.2
Mangino, M.3
-
70
-
-
66549084876
-
A HaemAtlas: characterizing gene expression in differentiated human blood cells
-
De S, Miranda-Saavedra D, Hardie DL, Angenent WG, Attwood AP, Ellis PD, Erber W, et al
-
Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, Hardie DL, Angenent WG, Attwood AP, Ellis PD, Erber W, et al. A HaemAtlas:characterizing gene expression in differentiated human blood cells. Blood 2009;113:e1–e9.
-
(2009)
Blood
, vol.113
, pp. e1-e9
-
-
Watkins, N.A.1
Gusnanto, A.2
de Bono, B.3
-
71
-
-
0028980648
-
Genetic polymorphism of the alpha 2-adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive humans
-
Freeman K, Farrow S, Schmaier A, Freedman R, Schork T, Lockette W. Genetic polymorphism of the alpha 2-adrenergic receptor is associated with increased platelet aggregation, baroreceptor sensitivity, and salt excretion in normotensive humans. Am J Hypertens 1995;8:863–869.
-
(1995)
Am J Hypertens
, vol.8
, pp. 863-869
-
-
Freeman, K.1
Farrow, S.2
Schmaier, A.3
-
72
-
-
0030061416
-
Prevalence of impaired responsiveness to epinephrine in platelets among Japanese
-
Ariyoshi H, Kawasaki T, Sakon M, Monden M
-
Kambayashi J, Shinoki N, Nakamura T, Ariyoshi H, Kawasaki T, Sakon M, Monden M. Prevalence of impaired responsiveness to epinephrine in platelets among Japanese. Thromb Res 1996;81:85–90.
-
(1996)
Thromb Res
, vol.81
, pp. 85-90
-
-
Kambayashi, J.1
Shinoki, N.2
Nakamura, T.3
-
73
-
-
0035949498
-
Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction
-
Hampton KK, Steeds RP, Channer KS, Daly ME
-
Croft SA, Samani NJ, Teare MD, Hampton KK, Steeds RP, Channer KS, Daly ME. Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction. Circulation 2001;104:1459–1463.
-
(2001)
Circulation
, vol.104
, pp. 1459-1463
-
-
Croft, S.A.1
Samani, N.J.2
Teare, M.D.3
-
74
-
-
52449108714
-
A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability
-
Herrera-Galeano JE, Becker DM, Wilson AF, Yanek LR, Bray P, Vaidya D, Faraday N, Becker LC. A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability. Arterioscler Thromb Vasc Biol 2008;28:1484–1490.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1484-1490
-
-
Herrera-Galeano, J.E.1
Becker, D.M.2
Wilson, A.F.3
-
75
-
-
84886391924
-
Genetic variation of platelet function and pharmacology: an update of current knowledge
-
Geisler T, Schaeffeler E, Gawaz M, Schwab M., Genetic variation of platelet function and pharmacology:an update of current knowledge. Thromb Haemost 2013;110(5):876–887.
-
(2013)
Thromb Haemost
, vol.110
, Issue.5
, pp. 876-887
-
-
Geisler, T.1
Schaeffeler, E.2
Gawaz, M.3
Schwab, M.4
-
76
-
-
84974555434
-
Personalized medicine in thrombosis: back to the future
-
Feb 4, pii: blood-2015-11-634832. [Epub ahead of print]
-
Nagalla S, Bray PF., Personalized medicine in thrombosis:back to the future. Blood 2016 Feb 4. pii:blood-2015-11-634832. [Epub ahead of print]
-
(2016)
Blood
-
-
Nagalla, S.1
Bray, P.F.2
-
77
-
-
77649184039
-
Genome-wide association study of hematological and biochemical traits in a Japanese population
-
Mar
-
Kamatani Y, Matsuda K, Okada Y, Kubo M, Hosono N, Daigo Y, Nakamura, Y, Kamatani N. Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat Genet 2010 Mar;42(3):210–215.
-
(2010)
Nat Genet
, vol.42
, Issue.3
, pp. 210-215
-
-
Kamatani, Y.1
Matsuda, K.2
Okada, Y.3
Kubo, M.4
Hosono, N.5
Daigo, N.6
Kamatani, Y.7
-
78
-
-
58049220179
-
A genome-wide association study identifies three loci associated with mean platelet volume
-
Jan
-
Meisinger C, Prokisch H, Gieger C, Soranzo N, Mehta D, Rosskopf D, Lichtner P, Klopp N, Stephens J, Watkins NA, Deloukas P, et al. A genome-wide association study identifies three loci associated with mean platelet volume. Am J Hum Genet 2009 Jan;84(1):66–71.
-
(2009)
Am J Hum Genet
, vol.84
, Issue.1
, pp. 66-71
-
-
Meisinger, C.1
Prokisch, H.2
Gieger, C.3
Soranzo, N.4
Mehta, D.5
Rosskopf, D.6
Lichtner, P.7
Klopp, N.8
Stephens, J.9
Watkins, N.A.10
Deloukas, P.11
|