A Loss of Function Screen of Identified Genome-Wide Association Study Loci Reveals New Genes Controlling Hematopoiesis

PLoS Genetics

Volumn 10, Issue 7, 2014, Pages

  Bielczyk Maczyńska, Ewa ^a,b,c   Serbanovic Canic, Jovana ^d   Ferreira, Lauren ^a,b   Soranzo, Nicole ^a,b   Stemple, Derek L ^b   Ouwehand, Willem H ^a,b,c   Cvejic, Ana ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c NHS BLOOD AND TRANSPLANT   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE MORPHOLINO OLIGONUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; GENOMIC DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRD3A GENE; CELL COUNT; CELL SIZE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; GENE; GENE FUNCTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SCREENING; GENOTYPE; HEMATOPOIESIS; HISTOLOGY; IN SITU HYBRIDIZATION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOCYTE; THROMBOCYTOPOIESIS; ZEBRA FISH; ANIMAL; BLOOD; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; HEMATOPOIETIC STEM CELL; HUMAN; META ANALYSIS; METABOLISM;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION PROFILING; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; ZEBRAFISH;

EID: 84905455420     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004450     Document Type: Article

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