Genetic variation of platelet function and pharmacology: An update of current knowledge

Thrombosis and Haemostasis

Volumn 110, Issue 5, 2013, Pages 876-887

  Geisler, Tobias ^a   Schaeffeler, Elke ^a   Gawaz, Meinrad ^a   Schwab, Matthias ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Platelet pharmacology; Platelet physiology; Polymorphisms

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA 2A ADRENERGIC RECEPTOR; ALPHA2 INTEGRIN; ANTITHROMBOCYTIC AGENT; APIXABAN; ARYLDIALKYLPHOSPHATASE; ATOPAXAR; CLOPIDOGREL; CYCLOOXYGENASE 1; CYTOCHROME P450 2C19; DABIGATRAN; DRUG METABOLIZING ENZYME; FC RECEPTOR IIA; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIIA; GLYCOPROTEIN VI; JANUS KINASE 2; PADGEM PROTEIN; PLACEBO; PRASUGREL; PROTEINASE ACTIVATED RECEPTOR 1; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; RIVAROXABAN; THROMBOCYTE RECEPTOR; THROMBOXANE A2 RECEPTOR; TICAGRELOR; UNINDEXED DRUG; VERY LATE ACTIVATION ANTIGEN 2; VORAPAXAR;

ACUTE CORONARY SYNDROME; ARTICLE; BLEEDING; CARDIOVASCULAR DISEASE; CEREBROVASCULAR ACCIDENT; CLINICAL PHARMACOLOGY; CORONARY ARTERY DISEASE; DRUG DOSE INCREASE; DRUG EFFICACY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GENOMICS; HEART DEATH; HEART INFARCTION; HUMAN; LOADING DRUG DOSE; META ANALYSIS (TOPIC); PHARMACOGENETICS; PHASE 2 CLINICAL TRIAL (TOPIC); PHENOTYPIC VARIATION; PLATELET REACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE NUCLEOTIDE POLYMORPHISM; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOCYTE VOLUME;

PLATELET PHARMACOLOGY; PLATELET PHYSIOLOGY; POLYMORPHISMS;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; PLATELET AGGREGATION INHIBITORS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RECEPTORS, COLLAGEN; RECEPTORS, FIBRINOGEN; RECEPTORS, PURINERGIC P2Y; RISK;

EID: 84886391924     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-02-0145     Document Type: Article

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