-
1
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
[1] Sakai, W., et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 451:7182 (2008), 1116–1120.
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1116-1120
-
-
Sakai, W.1
-
2
-
-
33646568511
-
Mechanisms and strategies to overcome multiple drug resistance in cancer
-
[2] Ozben, T., Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett. 580:12 (2006), 2903–2909.
-
(2006)
FEBS Lett.
, vol.580
, Issue.12
, pp. 2903-2909
-
-
Ozben, T.1
-
3
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
[3] Vander Heiden, M.G., Cantley, L.C., Thompson, C.B., Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:5930 (2009), 1029–1033.
-
(2009)
Science
, vol.324
, Issue.5930
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
4
-
-
12544256565
-
Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
-
[4] Xu, R.H., et al. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 65:2 (2005), 613–621.
-
(2005)
Cancer Res.
, vol.65
, Issue.2
, pp. 613-621
-
-
Xu, R.H.1
-
5
-
-
84937798733
-
L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation
-
[5] Wagner, W., Ciszewski, W.M., Kania, K.D., L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation. Cell Commun. Signal., 13, 2015, 36.
-
(2015)
Cell Commun. Signal.
, vol.13
, pp. 36
-
-
Wagner, W.1
Ciszewski, W.M.2
Kania, K.D.3
-
6
-
-
84961219411
-
Hexokinase 2 is a determinant of neuroblastoma metastasis
-
[6] Botzer, L.E., et al. Hexokinase 2 is a determinant of neuroblastoma metastasis. Br. J. Cancer 114:7 (2016), 759–766.
-
(2016)
Br. J. Cancer
, vol.114
, Issue.7
, pp. 759-766
-
-
Botzer, L.E.1
-
7
-
-
84907883735
-
Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity
-
[7] Khiati, S., et al. Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity. Clin. Cancer Res. 20:18 (2014), 4873–4881.
-
(2014)
Clin. Cancer Res.
, vol.20
, Issue.18
, pp. 4873-4881
-
-
Khiati, S.1
-
8
-
-
33750564785
-
Anthracycline cardiotoxicity
-
[8] Jones, R.L., Swanton, C., Ewer, M.S., Anthracycline cardiotoxicity. Expert Opin. Drug Saf. 5:6 (2006), 791–809.
-
(2006)
Expert Opin. Drug Saf.
, vol.5
, Issue.6
, pp. 791-809
-
-
Jones, R.L.1
Swanton, C.2
Ewer, M.S.3
-
9
-
-
22044444055
-
Enhancement of cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line
-
[9] Yen, H.C., et al. Enhancement of cisplatin-induced apoptosis and caspase 3 activation by depletion of mitochondrial DNA in a human osteosarcoma cell line. Ann. N. Y. Acad. Sci. 1042 (2005), 516–522.
-
(2005)
Ann. N. Y. Acad. Sci.
, vol.1042
, pp. 516-522
-
-
Yen, H.C.1
-
10
-
-
27744452812
-
Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death
-
[10] Qian, W., et al. Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death. Am. J. Physiol. Cell Physiol. 289:6 (2005), C1466–C1475.
-
(2005)
Am. J. Physiol. Cell Physiol.
, vol.289
, Issue.6
, pp. C1466-C1475
-
-
Qian, W.1
-
11
-
-
84925283203
-
Overcoming 5-Fu resistance in human non-small cell lung cancer cells by the combination of 5-Fu and cisplatin through the inhibition of glucose metabolism
-
[11] Zhao, J.G., Ren, K.M., Tang, J., Overcoming 5-Fu resistance in human non-small cell lung cancer cells by the combination of 5-Fu and cisplatin through the inhibition of glucose metabolism. Tumour Biol. 35:12 (2014), 12305–12315.
-
(2014)
Tumour Biol.
, vol.35
, Issue.12
, pp. 12305-12315
-
-
Zhao, J.G.1
Ren, K.M.2
Tang, J.3
-
12
-
-
84947224189
-
Targeting cellular metabolism chemosensitizes the doxorubicin-resistant human breast adenocarcinoma cells
-
[12] Ma, S., et al. Targeting cellular metabolism chemosensitizes the doxorubicin-resistant human breast adenocarcinoma cells. Biomed. Res. Int., 2015, 2015, 453986.
-
(2015)
Biomed. Res. Int.
, vol.2015
, pp. 453986
-
-
Ma, S.1
-
13
-
-
82955173044
-
Drug resistance and cellular adaptation to tumor acidic pH microenvironment
-
[13] Wojtkowiak, J.W., et al. Drug resistance and cellular adaptation to tumor acidic pH microenvironment. Mol. Pharm. 8:6 (2011), 2032–2038.
-
(2011)
Mol. Pharm.
, vol.8
, Issue.6
, pp. 2032-2038
-
-
Wojtkowiak, J.W.1
-
14
-
-
0030942009
-
Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan
-
[14] Vukovic, V., Tannock, I.F., Influence of low pH on cytotoxicity of paclitaxel, mitoxantrone and topotecan. Br. J. Cancer 75:8 (1997), 1167–1172.
-
(1997)
Br. J. Cancer
, vol.75
, Issue.8
, pp. 1167-1172
-
-
Vukovic, V.1
Tannock, I.F.2
-
15
-
-
33745110220
-
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
-
[15] Gerweck, L.E., Vijayappa, S., Kozin, S., Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics. Mol. Cancer Ther. 5:5 (2006), 1275–1279.
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.5
, pp. 1275-1279
-
-
Gerweck, L.E.1
Vijayappa, S.2
Kozin, S.3
-
16
-
-
84943380853
-
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread
-
[16] Giannoni, E., et al. Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs oxphos and prostate cancer metastatic spread. Oncotarget 6:27 (2015), 24061–24074.
-
(2015)
Oncotarget
, vol.6
, Issue.27
, pp. 24061-24074
-
-
Giannoni, E.1
-
17
-
-
84911861458
-
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
-
[17] Viale, A., et al. Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function. Nature 514:7524 (2014), 628–632.
-
(2014)
Nature
, vol.514
, Issue.7524
, pp. 628-632
-
-
Viale, A.1
-
18
-
-
84969730632
-
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer
-
[18] Matassa, D.S., et al. Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer. Cell Death Differ. 23:9 (2016), 1542–1554.
-
(2016)
Cell Death Differ.
, vol.23
, Issue.9
, pp. 1542-1554
-
-
Matassa, D.S.1
-
19
-
-
84941950274
-
SIRT1/PGC1α-dependent increase in oxidative phosphorylation supports chemotherapy resistance of colon cancer
-
[19] Vellinga, T.T., et al. SIRT1/PGC1α-dependent increase in oxidative phosphorylation supports chemotherapy resistance of colon cancer. Clin. Cancer Res. 21:12 (2015), 2870–2879.
-
(2015)
Clin. Cancer Res.
, vol.21
, Issue.12
, pp. 2870-2879
-
-
Vellinga, T.T.1
-
20
-
-
84991829685
-
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells
-
[20] Ippolito, L., et al. Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells. Oncotarget, 2016.
-
(2016)
Oncotarget
-
-
Ippolito, L.1
-
21
-
-
84855363557
-
Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells
-
[21] Zhou, Y., et al. Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells. Cancer Res. 72:1 (2012), 304–314.
-
(2012)
Cancer Res.
, vol.72
, Issue.1
, pp. 304-314
-
-
Zhou, Y.1
-
22
-
-
84969951574
-
Hallmarks of cancer stem cell metabolism
-
[22] Sancho, P., Barneda, D., Heeschen, C., Hallmarks of cancer stem cell metabolism. Br. J. Cancer 114:12 (2016), 1305–1312.
-
(2016)
Br. J. Cancer
, vol.114
, Issue.12
, pp. 1305-1312
-
-
Sancho, P.1
Barneda, D.2
Heeschen, C.3
-
23
-
-
84897544161
-
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
-
[23] Martinez-Outschoorn, U.E., Lisanti, M.P., Sotgia, F., Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth. Semin. Cancer Biol. 25 (2014), 47–60.
-
(2014)
Semin. Cancer Biol.
, vol.25
, pp. 47-60
-
-
Martinez-Outschoorn, U.E.1
Lisanti, M.P.2
Sotgia, F.3
-
24
-
-
84867112200
-
Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay
-
[24] Fiaschi, T., et al. Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay. Cancer Res. 72:19 (2012), 5130–5140.
-
(2012)
Cancer Res.
, vol.72
, Issue.19
, pp. 5130-5140
-
-
Fiaschi, T.1
-
25
-
-
84923194150
-
Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
-
[25] Fong, M.Y., et al. Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis. Nat. Cell Biol. 17:2 (2015), 183–194.
-
(2015)
Nat. Cell Biol.
, vol.17
, Issue.2
, pp. 183-194
-
-
Fong, M.Y.1
-
26
-
-
84953321022
-
Prognostic indications of elevated MCT4 and CD147 across cancer types: a meta-analysis
-
[26] Bovenzi, C.D., et al. Prognostic indications of elevated MCT4 and CD147 across cancer types: a meta-analysis. Biomed. Res. Int., 2015, 2015, 242437.
-
(2015)
Biomed. Res. Int.
, vol.2015
, pp. 242437
-
-
Bovenzi, C.D.1
-
27
-
-
84962179922
-
miR-155 drives metabolic reprogramming of ER + breast cancer cells following long-term estrogen deprivation and predicts clinical response to aromatase inhibitors
-
[27] Bacci, M., et al. miR-155 drives metabolic reprogramming of ER + breast cancer cells following long-term estrogen deprivation and predicts clinical response to aromatase inhibitors. Cancer Res., 2016.
-
(2016)
Cancer Res.
-
-
Bacci, M.1
-
28
-
-
84906282434
-
Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome
-
[28] Doyen, J., et al. Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome. Biochem. Biophys. Res. Commun. 451:1 (2014), 54–61.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.451
, Issue.1
, pp. 54-61
-
-
Doyen, J.1
-
29
-
-
84983543658
-
Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer
-
[29] Fribbens, C., et al. Plasma ESR1 mutations and the treatment of estrogen receptor-positive advanced breast cancer. J. Clin. Oncol. 34:25 (2016), 2961–2968.
-
(2016)
J. Clin. Oncol.
, vol.34
, Issue.25
, pp. 2961-2968
-
-
Fribbens, C.1
-
30
-
-
84924244611
-
Estrogen receptor mutations and their role in breast cancer progression
-
[30] Alluri, P.G., Speers, C., Chinnaiyan, A.M., Estrogen receptor mutations and their role in breast cancer progression. Breast Cancer Res., 16(6), 2014, 494.
-
(2014)
Breast Cancer Res.
, vol.16
, Issue.6
, pp. 494
-
-
Alluri, P.G.1
Speers, C.2
Chinnaiyan, A.M.3
-
31
-
-
84879108302
-
GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors
-
[31] Morandi, A., et al. GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res. 73:12 (2013), 3783–3795.
-
(2013)
Cancer Res.
, vol.73
, Issue.12
, pp. 3783-3795
-
-
Morandi, A.1
-
32
-
-
84941338833
-
Inhibition of aerobic glycolysis represses Akt/mTOR/HIF-1α axis and restores tamoxifen sensitivity in antiestrogen-resistant breast cancer cells
-
[32] Woo, Y.M., et al. Inhibition of aerobic glycolysis represses Akt/mTOR/HIF-1α axis and restores tamoxifen sensitivity in antiestrogen-resistant breast cancer cells. PLoS One, 10(7), 2015, e0132285.
-
(2015)
PLoS One
, vol.10
, Issue.7
, pp. e0132285
-
-
Woo, Y.M.1
-
33
-
-
79961118758
-
Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells
-
[33] Martinez-Outschoorn, U.E., et al. Understanding the metabolic basis of drug resistance: therapeutic induction of the Warburg effect kills cancer cells. Cell Cycle 10:15 (2011), 2521–2528.
-
(2011)
Cell Cycle
, vol.10
, Issue.15
, pp. 2521-2528
-
-
Martinez-Outschoorn, U.E.1
-
34
-
-
84894070673
-
Metabolic implication of tumor:stroma crosstalk in breast cancer
-
[34] Morandi, A., Chiarugi, P., Metabolic implication of tumor:stroma crosstalk in breast cancer. J. Mol. Med. (Berl.) 92:2 (2014), 117–126.
-
(2014)
J. Mol. Med. (Berl.)
, vol.92
, Issue.2
, pp. 117-126
-
-
Morandi, A.1
Chiarugi, P.2
-
35
-
-
84957921760
-
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer
-
[35] Sansone, P., et al. Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer. Nat. Commun., 7, 2016, 10442.
-
(2016)
Nat. Commun.
, vol.7
, pp. 10442
-
-
Sansone, P.1
-
36
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
[36] Bergers, G., Hanahan, D., Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8:8 (2008), 592–603.
-
(2008)
Nat. Rev. Cancer
, vol.8
, Issue.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
37
-
-
84926166792
-
Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality
-
[37] McIntyre, A., Harris, A.L., Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality. EMBO Mol. Med. 7:4 (2015), 368–379.
-
(2015)
EMBO Mol. Med.
, vol.7
, Issue.4
, pp. 368-379
-
-
McIntyre, A.1
Harris, A.L.2
-
38
-
-
84920532087
-
VEGF-targeted therapy stably modulates the glycolytic phenotype of tumor cells
-
[38] Curtarello, M., et al. VEGF-targeted therapy stably modulates the glycolytic phenotype of tumor cells. Cancer Res. 75:1 (2015), 120–133.
-
(2015)
Cancer Res.
, vol.75
, Issue.1
, pp. 120-133
-
-
Curtarello, M.1
-
39
-
-
84965100853
-
Metabolic symbiosis enables adaptive resistance to anti-angiogenic therapy that is dependent on mTOR signaling
-
[39] Allen, E., et al. Metabolic symbiosis enables adaptive resistance to anti-angiogenic therapy that is dependent on mTOR signaling. Cell Rep. 15:6 (2016), 1144–1160.
-
(2016)
Cell Rep.
, vol.15
, Issue.6
, pp. 1144-1160
-
-
Allen, E.1
-
40
-
-
84964685809
-
Resistance to antiangiogenic therapies by metabolic symbiosis in renal cell carcinoma PDX models and patients
-
[40] Jimenez-Valerio, G., et al. Resistance to antiangiogenic therapies by metabolic symbiosis in renal cell carcinoma PDX models and patients. Cell Rep. 15:6 (2016), 1134–1143.
-
(2016)
Cell Rep.
, vol.15
, Issue.6
, pp. 1134-1143
-
-
Jimenez-Valerio, G.1
-
41
-
-
84964682256
-
Targeting metabolic symbiosis to overcome resistance to anti-angiogenic therapy
-
[41] Pisarsky, L., et al. Targeting metabolic symbiosis to overcome resistance to anti-angiogenic therapy. Cell Rep. 15:6 (2016), 1161–1174.
-
(2016)
Cell Rep.
, vol.15
, Issue.6
, pp. 1161-1174
-
-
Pisarsky, L.1
-
42
-
-
84964300029
-
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
-
[42] Perez-Escuredo, J., et al. Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. Cell Cycle 15:1 (2016), 72–83.
-
(2016)
Cell Cycle
, vol.15
, Issue.1
, pp. 72-83
-
-
Perez-Escuredo, J.1
-
43
-
-
84899416850
-
Metabolic effects of antiangiogenic drugs in tumors: therapeutic implications
-
[43] Quintieri, L., Selmy, M., Indraccolo, S., Metabolic effects of antiangiogenic drugs in tumors: therapeutic implications. Biochem. Pharmacol. 89:2 (2014), 162–170.
-
(2014)
Biochem. Pharmacol.
, vol.89
, Issue.2
, pp. 162-170
-
-
Quintieri, L.1
Selmy, M.2
Indraccolo, S.3
-
44
-
-
84958138936
-
Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer
-
[44] Davidson, S.M., et al. Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer. Cell Metab. 23:3 (2016), 517–528.
-
(2016)
Cell Metab.
, vol.23
, Issue.3
, pp. 517-528
-
-
Davidson, S.M.1
-
45
-
-
84955326448
-
The emerging hallmarks of cancer metabolism
-
[45] Pavlova, N.N., Thompson, C.B., The emerging hallmarks of cancer metabolism. Cell Metab. 23:1 (2016), 27–47.
-
(2016)
Cell Metab.
, vol.23
, Issue.1
, pp. 27-47
-
-
Pavlova, N.N.1
Thompson, C.B.2
-
46
-
-
67349129399
-
Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies
-
[46] Rapisarda, A., Melillo, G., Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies. Drug Resist. Updat. 12:3 (2009), 74–80.
-
(2009)
Drug Resist. Updat.
, vol.12
, Issue.3
, pp. 74-80
-
-
Rapisarda, A.1
Melillo, G.2
-
47
-
-
84872596428
-
Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma
-
[47] Shen, Y.C., et al. Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma. Br. J. Cancer 108:1 (2013), 72–81.
-
(2013)
Br. J. Cancer
, vol.108
, Issue.1
, pp. 72-81
-
-
Shen, Y.C.1
-
48
-
-
84861762712
-
Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy
-
[48] McIntyre, A., et al. Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clin. Cancer Res. 18:11 (2012), 3100–3111.
-
(2012)
Clin. Cancer Res.
, vol.18
, Issue.11
, pp. 3100-3111
-
-
McIntyre, A.1
-
49
-
-
84977673155
-
Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity
-
[49] Eichner, R., et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat. Med. 22:7 (2016), 735–743.
-
(2016)
Nat. Med.
, vol.22
, Issue.7
, pp. 735-743
-
-
Eichner, R.1
-
50
-
-
84864402951
-
Anticancer agents that counteract tumor glycolysis
-
[50] Granchi, C., Minutolo, F., Anticancer agents that counteract tumor glycolysis. ChemMedChem 7:8 (2012), 1318–1350.
-
(2012)
ChemMedChem
, vol.7
, Issue.8
, pp. 1318-1350
-
-
Granchi, C.1
Minutolo, F.2
-
52
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
[52] Mancuso, M.R., et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J. Clin. Invest. 116:10 (2006), 2610–2621.
-
(2006)
J. Clin. Invest.
, vol.116
, Issue.10
, pp. 2610-2621
-
-
Mancuso, M.R.1
-
53
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
[53] Keunen, O., et al. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc. Natl. Acad. Sci. U. S. A. 108:9 (2011), 3749–3754.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.9
, pp. 3749-3754
-
-
Keunen, O.1
-
54
-
-
84905731719
-
Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal
-
[54] Sounni, N.E., et al. Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal. Cell Metab. 20:2 (2014), 280–294.
-
(2014)
Cell Metab.
, vol.20
, Issue.2
, pp. 280-294
-
-
Sounni, N.E.1
-
55
-
-
84908012698
-
Fatty acid uptake and lipid storage induced by HIF-1alpha contribute to cell growth and survival after hypoxia-reoxygenation
-
[55] Bensaad, K., et al. Fatty acid uptake and lipid storage induced by HIF-1alpha contribute to cell growth and survival after hypoxia-reoxygenation. Cell Rep. 9:1 (2014), 349–365.
-
(2014)
Cell Rep.
, vol.9
, Issue.1
, pp. 349-365
-
-
Bensaad, K.1
-
56
-
-
84953260059
-
Imaging metabolic heterogeneity in cancer
-
[56] Sengupta, D., Pratx, G., Imaging metabolic heterogeneity in cancer. Mol. Cancer, 15, 2016, 4.
-
(2016)
Mol. Cancer
, vol.15
, pp. 4
-
-
Sengupta, D.1
Pratx, G.2
-
57
-
-
79959861423
-
Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism
-
[57] Zhao, Y., et al. Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism. Cancer Res. 71:13 (2011), 4585–4597.
-
(2011)
Cancer Res.
, vol.71
, Issue.13
, pp. 4585-4597
-
-
Zhao, Y.1
-
58
-
-
84901007722
-
Resistance to the tyrosine kinase inhibitor axitinib is associated with increased glucose metabolism in pancreatic adenocarcinoma
-
[58] Hudson, C.D., et al. Resistance to the tyrosine kinase inhibitor axitinib is associated with increased glucose metabolism in pancreatic adenocarcinoma. Cell Death Dis., 5, 2014, e1160.
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1160
-
-
Hudson, C.D.1
-
59
-
-
84944076036
-
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia
-
[59] Herranz, D., et al. Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat. Med. 21:10 (2015), 1182–1189.
-
(2015)
Nat. Med.
, vol.21
, Issue.10
, pp. 1182-1189
-
-
Herranz, D.1
|