-
1
-
-
84868677556
-
Biochemistry and cell biology of tau protein in neurofibrillary degeneration
-
22762014 3385935
-
Mandelkow EM, Mandelkow E. Biochemistry and cell biology of tau protein in neurofibrillary degeneration. Cold Spring Harb Perspect Med. 2012;2:a006247.
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, pp. a006247
-
-
Mandelkow, E.M.1
Mandelkow, E.2
-
2
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
1:STN:280:DyaK387gtFOiug%3D%3D 1759558
-
Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991;82:239-59.
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
3
-
-
79451471618
-
The pathological process underlying Alzheimer's disease in individuals under thirty
-
21170538
-
Braak H, Del Tredici K. The pathological process underlying Alzheimer's disease in individuals under thirty. Acta Neuropathol. 2011;121:171-81.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 171-181
-
-
Braak, H.1
Del Tredici, K.2
-
4
-
-
0029967367
-
Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis
-
1:STN:280:DyaK28vjvFegtw%3D%3D 8841666
-
Braak H, Braak E. Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathol. 1996;92:197-201.
-
(1996)
Acta Neuropathol
, vol.92
, pp. 197-201
-
-
Braak, H.1
Braak, E.2
-
5
-
-
84884879594
-
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
-
1:CAS:528:DC%2BC3sXhtVOqtg%3D%3D 23200807
-
Yan MH, Wang X, Zhu X. Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease. Free Radic Biol Med. 2013;62:90-101.
-
(2013)
Free Radic Biol Med
, vol.62
, pp. 90-101
-
-
Yan, M.H.1
Wang, X.2
Zhu, X.3
-
6
-
-
84880950361
-
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication
-
23874151 3706306
-
Fruhbeis C, Frohlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Mobius W, Goebbels S, Nave KA, et al. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol. 2013;11:e1001604.
-
(2013)
PLoS Biol
, vol.11
, pp. e1001604
-
-
Fruhbeis, C.1
Frohlich, D.2
Kuo, W.P.3
Amphornrat, J.4
Thilemann, S.5
Saab, A.S.6
Kirchhoff, F.7
Mobius, W.8
Goebbels, S.9
Nave, K.A.10
-
7
-
-
0021145680
-
Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation
-
1:STN:280:DyaL2czgtVejsg%3D%3D 6474172
-
Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL. Alzheimer's disease: cell-specific pathology isolates the hippocampal formation. Science. 1984;225:1168-70.
-
(1984)
Science
, vol.225
, pp. 1168-1170
-
-
Hyman, B.T.1
Van Hoesen, G.W.2
Damasio, A.R.3
Barnes, C.L.4
-
8
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
1:CAS:528:DC%2BC38XisFyksr4%3D 22312444 3270029
-
Liu L, Drouet V, Wu JW, Witter MP, Small SA, Clelland C, Duff K. Trans-synaptic spread of tau pathology in vivo. PLoS One. 2012;7:e31302.
-
(2012)
PLoS One
, vol.7
, pp. e31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
9
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
22365544 3292759
-
de Calignon A, Polydoro M, Suarez-Calvet M, William C, Adamowicz DH, Kopeikina KJ, Pitstick R, Sahara N, Ashe KH, Carlson GA, et al. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron. 2012;73:685-97.
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
De Calignon, A.1
Polydoro, M.2
Suarez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
-
10
-
-
80052940324
-
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
-
1:CAS:528:DC%2BC3MXht1OgurfJ 21917794 4299126
-
Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J Neurosci. 2011;31:13110-7.
-
(2011)
J Neurosci
, vol.31
, pp. 13110-13117
-
-
Yamada, K.1
Cirrito, J.R.2
Stewart, F.R.3
Jiang, H.4
Finn, M.B.5
Holmes, B.B.6
Binder, L.I.7
Mandelkow, E.M.8
Diamond, M.I.9
Lee, V.M.10
Holtzman, D.M.11
-
11
-
-
84876459364
-
Physiological release of endogenous tau is stimulated by neuronal activity
-
1:CAS:528:DC%2BC3sXis1aht78%3D 23412472 3615658
-
Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 2013;14:389-94.
-
(2013)
EMBO Rep
, vol.14
, pp. 389-394
-
-
Pooler, A.M.1
Phillips, E.C.2
Lau, D.H.3
Noble, W.4
Hanger, D.P.5
-
12
-
-
84871141635
-
Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies
-
1:CAS:528:DC%2BC38XhvVeksbrN 23105105 3522274
-
Karch CM, Jeng AT, Goate AM. Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J Biol Chem. 2012;287:42751-62.
-
(2012)
J Biol Chem
, vol.287
, pp. 42751-42762
-
-
Karch, C.M.1
Jeng, A.T.2
Goate, A.M.3
-
13
-
-
84896830709
-
Neuronal activity regulates extracellular tau in vivo
-
1:CAS:528:DC%2BC2cXktlOmsbY%3D 24534188 3949564
-
Yamada K, Holth JK, Liao F, Stewart FR, Mahan TE, Jiang H, Cirrito JR, Patel TK, Hochgraefe K, Mandelkow E-M, Holtzman DM. Neuronal activity regulates extracellular tau in vivo. J Exp Med. 2014;211:387-93.
-
(2014)
J Exp Med
, vol.211
, pp. 387-393
-
-
Yamada, K.1
Holth, J.K.2
Liao, F.3
Stewart, F.R.4
Mahan, T.E.5
Jiang, H.6
Cirrito, J.R.7
Patel, T.K.8
Hochgraefe, K.9
Mandelkow, E.-M.10
Holtzman, D.M.11
-
14
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
1:CAS:528:DC%2BD1MXltlemsro%3D 19282288 2676015
-
Frost B, Jacks RL, Diamond MI. Propagation of tau misfolding from the outside to the inside of a cell. J Biol Chem. 2009;284:12845-52.
-
(2009)
J Biol Chem
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
15
-
-
79955441814
-
Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles
-
1:CAS:528:DC%2BC3MXltVSqu70%3D 21372138 3083182
-
Guo JL, Lee VM. Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles. J Biol Chem. 2011;286:15317-31.
-
(2011)
J Biol Chem
, vol.286
, pp. 15317-15331
-
-
Guo, J.L.1
Lee, V.M.2
-
16
-
-
84872714502
-
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
-
1:CAS:528:DC%2BC3sXhtFagu7Y%3D 23188818
-
Wu JW, Herman M, Liu L, Simoes S, Acker CM, Figueroa H, Steinberg JI, Margittai M, Kayed R, Zurzolo C, et al. Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem. 2013;288:1856-70.
-
(2013)
J Biol Chem
, vol.288
, pp. 1856-1870
-
-
Wu, J.W.1
Herman, M.2
Liu, L.3
Simoes, S.4
Acker, C.M.5
Figueroa, H.6
Steinberg, J.I.7
Margittai, M.8
Kayed, R.9
Zurzolo, C.10
-
17
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
1:CAS:528:DC%2BD1MXnvF2ku7g%3D 19503072 2726961
-
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol. 2009;11:909-13.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
-
18
-
-
84879232559
-
Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission
-
23773063
-
Mohamed NV, Herrou T, Plouffe V, Piperno N, Leclerc N. Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission. Eur J Neurosci. 2013;37:1939-48.
-
(2013)
Eur J Neurosci
, vol.37
, pp. 1939-1948
-
-
Mohamed, N.V.1
Herrou, T.2
Plouffe, V.3
Piperno, N.4
Leclerc, N.5
-
19
-
-
84873173557
-
Exosomes as a novel way of interneuronal communication
-
1:CAS:528:DC%2BC3sXhs1eiurs%3D 23356290
-
Chivet M, Javalet C, Hemming F, Pernet-Gallay K, Laulagnier K, Fraboulet S, Sadoul R. Exosomes as a novel way of interneuronal communication. Biochem Soc Trans. 2013;41:241-4.
-
(2013)
Biochem Soc Trans
, vol.41
, pp. 241-244
-
-
Chivet, M.1
Javalet, C.2
Hemming, F.3
Pernet-Gallay, K.4
Laulagnier, K.5
Fraboulet, S.6
Sadoul, R.7
-
20
-
-
84959386845
-
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
-
1:CAS:528:DC%2BC28Xit12rs70%3D 26858453 4776515
-
Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, Dingli F, Loew D, Tkach M, Thery C. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A. 2016;113:E968-77.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E968-E977
-
-
Kowal, J.1
Arras, G.2
Colombo, M.3
Jouve, M.4
Morath, J.P.5
Primdal-Bengtson, B.6
Dingli, F.7
Loew, D.8
Tkach, M.9
Thery, C.10
-
21
-
-
3142630225
-
Exosomes: Endosomal-derived vesicles shipping extracellular messages
-
1:CAS:528:DC%2BD2cXlsl2lu74%3D 15261674
-
Fevrier B, Raposo G. Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol. 2004;16:415-21.
-
(2004)
Curr Opin Cell Biol
, vol.16
, pp. 415-421
-
-
Fevrier, B.1
Raposo, G.2
-
22
-
-
84875495379
-
Regulation of postsynaptic retrograde signaling by presynaptic exosome release
-
1:CAS:528:DC%2BC3sXktlKqu70%3D 23522040 3626103
-
Korkut C, Li Y, Koles K, Brewer C, Ashley J, Yoshihara M, Budnik V. Regulation of postsynaptic retrograde signaling by presynaptic exosome release. Neuron. 2013;77:1039-46.
-
(2013)
Neuron
, vol.77
, pp. 1039-1046
-
-
Korkut, C.1
Li, Y.2
Koles, K.3
Brewer, C.4
Ashley, J.5
Yoshihara, M.6
Budnik, V.7
-
23
-
-
84939939990
-
Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation
-
1:CAS:528:DC%2BC2MXltVWmurc%3D 25778619 4405286
-
Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kugler S, Falomir Lockhart L, Schwalbe M, et al. Extracellular vesicle sorting of alpha-Synuclein is regulated by sumoylation. Acta Neuropathol. 2015;129:695-713.
-
(2015)
Acta Neuropathol
, vol.129
, pp. 695-713
-
-
Kunadt, M.1
Eckermann, K.2
Stuendl, A.3
Gong, J.4
Russo, B.5
Strauss, K.6
Rai, S.7
Kugler, S.8
Falomir Lockhart, L.9
Schwalbe, M.10
-
24
-
-
33746593662
-
Alzheimer's disease beta-amyloid peptides are released in association with exosomes
-
1:CAS:528:DC%2BD28XnvVamurk%3D 16837572 1544060
-
Rajendran L, Honsho M, Zahn TR, Keller P, Geiger KD, Verkade P, Simons K. Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc Natl Acad Sci U S A. 2006;103:11172-7.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11172-11177
-
-
Rajendran, L.1
Honsho, M.2
Zahn, T.R.3
Keller, P.4
Geiger, K.D.5
Verkade, P.6
Simons, K.7
-
25
-
-
3042788972
-
Cells release prions in association with exosomes
-
1:CAS:528:DC%2BD2cXlvVahtr4%3D 15210972 470735
-
Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G. Cells release prions in association with exosomes. Proc Natl Acad Sci U S A. 2004;101:9683-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9683-9688
-
-
Fevrier, B.1
Vilette, D.2
Archer, F.3
Loew, D.4
Faigle, W.5
Vidal, M.6
Laude, H.7
Raposo, G.8
-
26
-
-
84860221929
-
Tau overexpression results in its secretion via membrane vesicles
-
1:CAS:528:DC%2BC38XlvVOmsLo%3D 22269430
-
Simon D, Garcia-Garcia E, Gomez-Ramos A, Falcon-Perez JM, Diaz-Hernandez M, Hernandez F, Avila J. Tau overexpression results in its secretion via membrane vesicles. Neurodegener Dis. 2012;10:73-5.
-
(2012)
Neurodegener Dis
, vol.10
, pp. 73-75
-
-
Simon, D.1
Garcia-Garcia, E.2
Gomez-Ramos, A.3
Falcon-Perez, J.M.4
Diaz-Hernandez, M.5
Hernandez, F.6
Avila, J.7
-
27
-
-
84655176335
-
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
-
1:CAS:528:DC%2BC38XisVehuw%3D%3D 22138183
-
Simon D, Garcia-Garcia E, Royo F, Falcon-Perez JM, Avila J. Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett. 2012;586:47-54.
-
(2012)
FEBS Lett
, vol.586
, pp. 47-54
-
-
Simon, D.1
Garcia-Garcia, E.2
Royo, F.3
Falcon-Perez, J.M.4
Avila, J.5
-
28
-
-
84856707794
-
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
-
1:CAS:528:DC%2BC38XhvVSjt7w%3D 22057275
-
Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, Jackson B, McKee AC, Alvarez VE, Lee NC, Hall GF. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem. 2012;287:3842-9.
-
(2012)
J Biol Chem
, vol.287
, pp. 3842-3849
-
-
Saman, S.1
Kim, W.2
Raya, M.3
Visnick, Y.4
Miro, S.5
Saman, S.6
Jackson, B.7
McKee, A.C.8
Alvarez, V.E.9
Lee, N.C.10
Hall, G.F.11
-
29
-
-
33645357271
-
Exosomes are released by cultured cortical neurones
-
1:CAS:528:DC%2BD28XjtFOlsbg%3D 16446100
-
Faure J, Lachenal G, Court M, Hirrlinger J, Chatellard-Causse C, Blot B, Grange J, Schoehn G, Goldberg Y, Boyer V, et al. Exosomes are released by cultured cortical neurones. Mol Cell Neurosci. 2006;31:642-8.
-
(2006)
Mol Cell Neurosci
, vol.31
, pp. 642-648
-
-
Faure, J.1
Lachenal, G.2
Court, M.3
Hirrlinger, J.4
Chatellard-Causse, C.5
Blot, B.6
Grange, J.7
Schoehn, G.8
Goldberg, Y.9
Boyer, V.10
-
30
-
-
33644851265
-
Inducible expression of Tau repeat domain in cell models of tauopathy: Aggregation is toxic to cells but can be reversed by inhibitor drugs
-
1:CAS:528:DC%2BD28Xit1Sitg%3D%3D 16246844
-
Khlistunova I, Biernat J, Wang Y, Pickhardt M, von Bergen M, Gazova Z, Mandelkow E, Mandelkow EM. Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs. J Biol Chem. 2006;281:1205-14.
-
(2006)
J Biol Chem
, vol.281
, pp. 1205-1214
-
-
Khlistunova, I.1
Biernat, J.2
Wang, Y.3
Pickhardt, M.4
Von Bergen, M.5
Gazova, Z.6
Mandelkow, E.7
Mandelkow, E.M.8
-
31
-
-
84873438430
-
Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors
-
1:CAS:528:DC%2BC38XhslSmu7rO 23158765
-
Messing L, Decker JM, Joseph M, Mandelkow E, Mandelkow EM. Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors. Neurobiol Aging. 2013;34:1343-54.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 1343-1354
-
-
Messing, L.1
Decker, J.M.2
Joseph, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
32
-
-
43249109372
-
Clayton A: Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
Chapter 3:Unit 3 22
-
Thery C, Amigorena S, Raposo G, Clayton A: Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol 2006, Chapter 3:Unit 3 22.
-
(2006)
Curr Protoc Cell Biol
-
-
Thery, C.1
Amigorena, S.2
Raposo, G.3
-
33
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
1:STN:280:DyaL2c3ks1altQ%3D%3D 6610841
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-44.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
34
-
-
84977123370
-
Induction of alpha-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies
-
26647156
-
Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of alpha-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain. 2016;139:481-94.
-
(2016)
Brain
, vol.139
, pp. 481-494
-
-
Stuendl, A.1
Kunadt, M.2
Kruse, N.3
Bartels, C.4
Moebius, W.5
Danzer, K.M.6
Mollenhauer, B.7
Schneider, A.8
-
35
-
-
25644458666
-
Automated electron microscope tomography using robust prediction of specimen movements
-
16182563
-
Mastronarde DN. Automated electron microscope tomography using robust prediction of specimen movements. J Struct Biol. 2005;152:36-51.
-
(2005)
J Struct Biol
, vol.152
, pp. 36-51
-
-
Mastronarde, D.N.1
-
36
-
-
84926476627
-
Higher-order architecture of rhodopsin in intact photoreceptors and its implication for phototransduction kinetics
-
1:CAS:528:DC%2BC2MXjs1Grs70%3D 25728926
-
Gunkel M, Schoneberg J, Alkhaldi W, Irsen S, Noe F, Kaupp UB, Al-Amoudi A. Higher-order architecture of rhodopsin in intact photoreceptors and its implication for phototransduction kinetics. Structure. 2015;23:628-38.
-
(2015)
Structure
, vol.23
, pp. 628-638
-
-
Gunkel, M.1
Schoneberg, J.2
Alkhaldi, W.3
Irsen, S.4
Noe, F.5
Kaupp, U.B.6
Al-Amoudi, A.7
-
37
-
-
0031422417
-
Dual-axis tomography: An approach with alignment methods that preserve resolution
-
1:STN:280:DyaK1c7htVaqsQ%3D%3D 9441937
-
Mastronarde DN. Dual-axis tomography: an approach with alignment methods that preserve resolution. J Struct Biol. 1997;120:343-52.
-
(1997)
J Struct Biol
, vol.120
, pp. 343-352
-
-
Mastronarde, D.N.1
-
38
-
-
34547203592
-
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
-
1:CAS:528:DC%2BD2sXmvVCms7k%3D 17535890 1891218
-
Wang YP, Biernat J, Pickhardt M, Mandelkow E, Mandelkow EM. Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model. Proc Natl Acad Sci U S A. 2007;104:10252-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 10252-10257
-
-
Wang, Y.P.1
Biernat, J.2
Pickhardt, M.3
Mandelkow, E.4
Mandelkow, E.M.5
-
39
-
-
78751703517
-
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity
-
1:CAS:528:DC%2BC3MXhtlalu74%3D 21111824
-
Lachenal G, Pernet-Gallay K, Chivet M, Hemming FJ, Belly A, Bodon G, Blot B, Haase G, Goldberg Y, Sadoul R. Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity. Mol Cell Neurosci. 2011;46:409-18.
-
(2011)
Mol Cell Neurosci
, vol.46
, pp. 409-418
-
-
Lachenal, G.1
Pernet-Gallay, K.2
Chivet, M.3
Hemming, F.J.4
Belly, A.5
Bodon, G.6
Blot, B.7
Haase, G.8
Goldberg, Y.9
Sadoul, R.10
-
40
-
-
0041689948
-
Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
-
1:CAS:528:DC%2BD3sXmvVeisrc%3D 12888622 187753
-
Gamblin TC, Chen F, Zambrano A, Abraha A, Lagalwar S, Guillozet AL, Lu M, Fu Y, Garcia-Sierra F, LaPointe N, et al. Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease. Proc Natl Acad Sci U S A. 2003;100:10032-7.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10032-10037
-
-
Gamblin, T.C.1
Chen, F.2
Zambrano, A.3
Abraha, A.4
Lagalwar, S.5
Guillozet, A.L.6
Lu, M.7
Fu, Y.8
Garcia-Sierra, F.9
LaPointe, N.10
-
41
-
-
84903535019
-
Ectosomes: A new mechanism for non-exosomal secretion of tau protein
-
24971751 4074092
-
Dujardin S, Begard S, Caillierez R, Lachaud C, Delattre L, Carrier S, Loyens A, Galas MC, Bousset L, Melki R, et al. Ectosomes: a new mechanism for non-exosomal secretion of tau protein. PLoS One. 2014;9:e100760.
-
(2014)
PLoS One
, vol.9
, pp. e100760
-
-
Dujardin, S.1
Begard, S.2
Caillierez, R.3
Lachaud, C.4
Delattre, L.5
Carrier, S.6
Loyens, A.7
Galas, M.C.8
Bousset, L.9
Melki, R.10
-
42
-
-
77649101462
-
Nanostructural and transcriptomic analyses of human saliva derived exosomes
-
20052414 2797607
-
Palanisamy V, Sharma S, Deshpande A, Zhou H, Gimzewski J, Wong DT. Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One. 2010;5:e8577.
-
(2010)
PLoS One
, vol.5
, pp. e8577
-
-
Palanisamy, V.1
Sharma, S.2
Deshpande, A.3
Zhou, H.4
Gimzewski, J.5
Wong, D.T.6
-
43
-
-
84867118648
-
Exosomes and microvesicles: Extracellular vesicles for genetic information transfer and gene therapy
-
1:CAS:528:DC%2BC38XhsVarsbfN 22872698
-
Lee Y, El Andaloussi S, Wood MJ. Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy. Hum Mol Genet. 2012;21:R125-34.
-
(2012)
Hum Mol Genet
, vol.21
, pp. R125-R134
-
-
Lee, Y.1
El Andaloussi, S.2
Wood, M.J.3
-
44
-
-
84903541550
-
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: Relevance to sporadic tauopathies
-
24479894 3922636
-
Dujardin S, Lecolle K, Caillierez R, Begard S, Zommer N, Lachaud C, Carrier S, Dufour N, Auregan G, Winderickx J, et al. Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol Commun. 2014;2:14.
-
(2014)
Acta Neuropathol Commun
, vol.2
, pp. 14
-
-
Dujardin, S.1
Lecolle, K.2
Caillierez, R.3
Begard, S.4
Zommer, N.5
Lachaud, C.6
Carrier, S.7
Dufour, N.8
Auregan, G.9
Winderickx, J.10
-
45
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
1:CAS:528:DC%2BD1MXht1CrtrrI 19654187 2758146
-
Wang Y, Martinez-Vicente M, Kruger U, Kaushik S, Wong E, Mandelkow EM, Cuervo AM, Mandelkow E. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum Mol Genet. 2009;18:4153-70.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Kruger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
46
-
-
33750805030
-
Molecular anatomy of a trafficking organelle
-
1:CAS:528:DC%2BD28Xht1yqs7vE 17110340
-
Takamori S, Holt M, Stenius K, Lemke EA, Gronborg M, Riedel D, Urlaub H, Schenck S, Brugger B, Ringler P, et al. Molecular anatomy of a trafficking organelle. Cell. 2006;127:831-46.
-
(2006)
Cell
, vol.127
, pp. 831-846
-
-
Takamori, S.1
Holt, M.2
Stenius, K.3
Lemke, E.A.4
Gronborg, M.5
Riedel, D.6
Urlaub, H.7
Schenck, S.8
Brugger, B.9
Ringler, P.10
-
47
-
-
58849089529
-
Mechanisms of regulated unconventional protein secretion
-
Nickel W and Rabouille C. Mechanisms of regulated unconventional protein secretion.Nat Rev Mol Cell Biol. 2009;10(2):148-55.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, Issue.2
, pp. 148-155
-
-
Nickel, W.1
Rabouille, C.2
-
48
-
-
77049123465
-
Interneuronal transfer of human tau between Lamprey central neurons in situ
-
1:CAS:528:DC%2BC3cXht1SltLo%3D 20110609
-
Kim W, Lee S, Jung C, Ahmed A, Lee G, Hall GF. Interneuronal transfer of human tau between Lamprey central neurons in situ. J Alzheimers Dis. 2010;19:647-64.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 647-664
-
-
Kim, W.1
Lee, S.2
Jung, C.3
Ahmed, A.4
Lee, G.5
Hall, G.F.6
-
49
-
-
84862003756
-
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes
-
1:CAS:528:DC%2BC38Xot1Kjurc%3D 22496370 3370237
-
Santa-Maria I, Varghese M, Ksiezak-Reding H, Dzhun A, Wang J, Pasinetti GM. Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. J Biol Chem. 2012;287:20522-33.
-
(2012)
J Biol Chem
, vol.287
, pp. 20522-20533
-
-
Santa-Maria, I.1
Varghese, M.2
Ksiezak-Reding, H.3
Dzhun, A.4
Wang, J.5
Pasinetti, G.M.6
-
50
-
-
84938490181
-
C-Terminally Truncated Forms of Tau, but Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death
-
1:CAS:528:DC%2BC2MXhsVGksrnF 26224867
-
Kanmert D, Cantlon A, Muratore CR, Jin M, O'Malley TT, Lee G, Young-Pearse TL, Selkoe DJ, Walsh DM. C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death. J Neurosci. 2015;35:10851-65.
-
(2015)
J Neurosci
, vol.35
, pp. 10851-10865
-
-
Kanmert, D.1
Cantlon, A.2
Muratore, C.R.3
Jin, M.4
O'Malley, T.T.5
Lee, G.6
Young-Pearse, T.L.7
Selkoe, D.J.8
Walsh, D.M.9
-
51
-
-
84931577633
-
Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study
-
25130657 e601
-
Fiandaca MS, Kapogiannis D, Mapstone M, Boxer A, Eitan E, Schwartz JB, Abner EL, Petersen RC, Federoff HJ, Miller BL, Goetzl EJ. Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study. Alzheimers Dement. 2015;11:600-7. e601.
-
(2015)
Alzheimers Dement
, vol.11
, pp. 600-607
-
-
Fiandaca, M.S.1
Kapogiannis, D.2
Mapstone, M.3
Boxer, A.4
Eitan, E.5
Schwartz, J.B.6
Abner, E.L.7
Petersen, R.C.8
Federoff, H.J.9
Miller, B.L.10
Goetzl, E.J.11
-
52
-
-
84947284577
-
Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers
-
26426747 4591334
-
Lugli G, Cohen AM, Bennett DA, Shah RC, Fields CJ, Hernandez AG, Smalheiser NR. Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers. PLoS One. 2015;10:e0139233.
-
(2015)
PLoS One
, vol.10
, pp. e0139233
-
-
Lugli, G.1
Cohen, A.M.2
Bennett, D.A.3
Shah, R.C.4
Fields, C.J.5
Hernandez, A.G.6
Smalheiser, N.R.7
-
53
-
-
84865307818
-
Exosomal cell-to-cell transmission of alpha synuclein oligomers
-
1:CAS:528:DC%2BC38XhvVSiurvJ 22920859 3483256
-
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol Neurodegener. 2012;7:42.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 42
-
-
Danzer, K.M.1
Kranich, L.R.2
Ruf, W.P.3
Cagsal-Getkin, O.4
Winslow, A.R.5
Zhu, L.6
Vanderburg, C.R.7
McLean, P.J.8
-
54
-
-
84969262605
-
Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
-
1:CAS:528:DC%2BC28XhslCitrjP 27114500 5084269
-
Heusermann W, Hean J, Trojer D, Steib E, von Bueren S, Graff-Meyer A, Genoud C, Martin K, Pizzato N, Voshol J, et al. Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. J Cell Biol. 2016;213:173-84.
-
(2016)
J Cell Biol
, vol.213
, pp. 173-184
-
-
Heusermann, W.1
Hean, J.2
Trojer, D.3
Steib, E.4
Von Bueren, S.5
Graff-Meyer, A.6
Genoud, C.7
Martin, K.8
Pizzato, N.9
Voshol, J.10
-
55
-
-
84945474523
-
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
-
1:CAS:528:DC%2BC2MXhs1Wls7bJ 26436904 4694577
-
Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kugler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci. 2015;18:1584-93.
-
(2015)
Nat Neurosci
, vol.18
, pp. 1584-1593
-
-
Asai, H.1
Ikezu, S.2
Tsunoda, S.3
Medalla, M.4
Luebke, J.5
Haydar, T.6
Wolozin, B.7
Butovsky, O.8
Kugler, S.9
Ikezu, T.10
-
56
-
-
84929951298
-
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation
-
1:CAS:528:DC%2BC2MXosVaqt74%3D 25981034
-
Calafate S, Buist A, Miskiewicz K, Vijayan V, Daneels G, de Strooper B, de Wit J, Verstreken P, Moechars D. Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation. Cell Rep. 2015;11:1176-83.
-
(2015)
Cell Rep
, vol.11
, pp. 1176-1183
-
-
Calafate, S.1
Buist, A.2
Miskiewicz, K.3
Vijayan, V.4
Daneels, G.5
De Strooper, B.6
De Wit, J.7
Verstreken, P.8
Moechars, D.9
-
57
-
-
84944088611
-
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain
-
1:CAS:528:DC%2BC2MXhs1KksrnL 26458742 4608380
-
Takeda S, Wegmann S, Cho H, DeVos SL, Commins C, Roe AD, Nicholls SB, Carlson GA, Pitstick R, Nobuhara CK, et al. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain. Nat Commun. 2015;6:8490.
-
(2015)
Nat Commun
, vol.6
, pp. 8490
-
-
Takeda, S.1
Wegmann, S.2
Cho, H.3
DeVos, S.L.4
Commins, C.5
Roe, A.D.6
Nicholls, S.B.7
Carlson, G.A.8
Pitstick, R.9
Nobuhara, C.K.10
-
58
-
-
84876908676
-
Tau passive immunotherapy in mutant P301L mice: Antibody affinity versus specificity
-
23638068 3639259
-
d'Abramo C, Acker CM, Jimenez HT, Davies P. Tau passive immunotherapy in mutant P301L mice: antibody affinity versus specificity. PLoS One. 2013;8:e62402.
-
(2013)
PLoS One
, vol.8
, pp. e62402
-
-
D'Abramo, C.1
Acker, C.M.2
Jimenez, H.T.3
Davies, P.4
-
59
-
-
84896269359
-
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles
-
24647946
-
Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J Neurosci. 2014;34:4260-72.
-
(2014)
J Neurosci
, vol.34
, pp. 4260-4272
-
-
Castillo-Carranza, D.L.1
Sengupta, U.2
Guerrero-Munoz, M.J.3
Lasagna-Reeves, C.A.4
Gerson, J.E.5
Singh, G.6
Estes, D.M.7
Barrett, A.D.8
Dineley, K.T.9
Jackson, G.R.10
Kayed, R.11
-
60
-
-
84885783467
-
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo
-
1:CAS:528:DC%2BC3sXhsFems73N 24075978 3924573
-
Yanamandra K, Kfoury N, Jiang H, Mahan TE, Ma S, Maloney SE, Wozniak DF, Diamond MI, Holtzman DM. Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo. Neuron. 2013;80:402-14.
-
(2013)
Neuron
, vol.80
, pp. 402-414
-
-
Yanamandra, K.1
Kfoury, N.2
Jiang, H.3
Mahan, T.E.4
Ma, S.5
Maloney, S.E.6
Wozniak, D.F.7
Diamond, M.I.8
Holtzman, D.M.9
-
62
-
-
79551542416
-
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
-
1:CAS:528:DC%2BC3MXisFyjsro%3D 21242314
-
Fitzner D, Schnaars M, van Rossum D, Krishnamoorthy G, Dibaj P, Bakhti M, Regen T, Hanisch UK, Simons M. Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J Cell Sci. 2011;124:447-58.
-
(2011)
J Cell Sci
, vol.124
, pp. 447-458
-
-
Fitzner, D.1
Schnaars, M.2
Van Rossum, D.3
Krishnamoorthy, G.4
Dibaj, P.5
Bakhti, M.6
Regen, T.7
Hanisch, U.K.8
Simons, M.9
|