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Volumn 15, Issue 2, 2017, Pages 166-174

Management of Clostridium difficile Infection in Inflammatory Bowel Disease: Expert Review from the Clinical Practice Updates Committee of the AGA Institute

Author keywords

[No Author keywords available]

Indexed keywords

FIDAXOMICIN; IMMUNOSUPPRESSIVE AGENT; METRONIDAZOLE; STEROID; VANCOMYCIN; ANTIINFECTIVE AGENT;

EID: 85009354128     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2016.10.024     Document Type: Review
Times cited : (116)

References (63)
  • 1
    • 84937028983 scopus 로고    scopus 로고
    • Clostridium difficile infection
    • 1 Leffler, D.A., Lamont, J.T., Clostridium difficile infection. N Engl J Med 373 (2015), 287–288.
    • (2015) N Engl J Med , vol.373 , pp. 287-288
    • Leffler, D.A.1    Lamont, J.T.2
  • 2
    • 77951026738 scopus 로고    scopus 로고
    • Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
    • 2 Cohen, S.H., Gerding, D.N., Johnson, S., et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 31 (2010), 431–455.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 431-455
    • Cohen, S.H.1    Gerding, D.N.2    Johnson, S.3
  • 3
    • 0017801430 scopus 로고
    • Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia
    • 3 Bartlett, J.G., Chang, T.W., Gurwith, M., et al. Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia. N Engl J Med 298 (1978), 531–534.
    • (1978) N Engl J Med , vol.298 , pp. 531-534
    • Bartlett, J.G.1    Chang, T.W.2    Gurwith, M.3
  • 4
    • 0018193196 scopus 로고
    • Clostridium difficile and the aetiology of pseudomembranous colitis
    • 4 Larson, H.E., Price, A.B., Honour, P., et al. Clostridium difficile and the aetiology of pseudomembranous colitis. Lancet 1 (1978), 1063–1066.
    • (1978) Lancet , vol.1 , pp. 1063-1066
    • Larson, H.E.1    Price, A.B.2    Honour, P.3
  • 5
    • 55249105923 scopus 로고    scopus 로고
    • Clostridium difficile–more difficult than ever
    • 5 Kelly, C.P., LaMont, J.T., Clostridium difficile–more difficult than ever. N Engl J Med 359 (2008), 1932–1940.
    • (2008) N Engl J Med , vol.359 , pp. 1932-1940
    • Kelly, C.P.1    LaMont, J.T.2
  • 6
    • 84923775846 scopus 로고    scopus 로고
    • Burden of Clostridium difficile infection in the United States
    • 6 Lessa, F.C., Mu, Y., Bamberg, W.M., et al. Burden of Clostridium difficile infection in the United States. N Engl J Med 372 (2015), 825–834.
    • (2015) N Engl J Med , vol.372 , pp. 825-834
    • Lessa, F.C.1    Mu, Y.2    Bamberg, W.M.3
  • 7
    • 33644523410 scopus 로고    scopus 로고
    • Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003
    • 7 McDonald, L.C., Owings, M., Jernigan, D.B., Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996-2003. Emerg Infect Dis 12 (2006), 409–415.
    • (2006) Emerg Infect Dis , vol.12 , pp. 409-415
    • McDonald, L.C.1    Owings, M.2    Jernigan, D.B.3
  • 8
    • 28844494086 scopus 로고    scopus 로고
    • An epidemic, toxin gene-variant strain of Clostridium difficile
    • 8 McDonald, L.C., Killgore, G.E., Thompson, A., et al. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 353 (2005), 2433–2441.
    • (2005) N Engl J Med , vol.353 , pp. 2433-2441
    • McDonald, L.C.1    Killgore, G.E.2    Thompson, A.3
  • 9
    • 28844441314 scopus 로고    scopus 로고
    • A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
    • 9 Loo, V.G., Poirier, L., Miller, M.A., et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 353 (2005), 2442–2449.
    • (2005) N Engl J Med , vol.353 , pp. 2442-2449
    • Loo, V.G.1    Poirier, L.2    Miller, M.A.3
  • 10
    • 65449155189 scopus 로고    scopus 로고
    • Clostridium difficile infection caused by the epidemic BI/NAP1/027 strain
    • 10 O'Connor, J.R., Johnson, S., Gerding, D.N., Clostridium difficile infection caused by the epidemic BI/NAP1/027 strain. Gastroenterology 136 (2009), 1913–1924.
    • (2009) Gastroenterology , vol.136 , pp. 1913-1924
    • O'Connor, J.R.1    Johnson, S.2    Gerding, D.N.3
  • 11
    • 0018892191 scopus 로고
    • Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease
    • 11 LaMont, J.T., Trnka, Y.M., Therapeutic implications of Clostridium difficile toxin during relapse of chronic inflammatory bowel disease. Lancet 1 (1980), 381–383.
    • (1980) Lancet , vol.1 , pp. 381-383
    • LaMont, J.T.1    Trnka, Y.M.2
  • 12
    • 58849083648 scopus 로고    scopus 로고
    • Increasing incidence of Clostridium difficile-associated diarrhea in inflammatory bowel disease
    • 12 Bossuyt, P., Verhaegen, J., Van Assche, G., et al. Increasing incidence of Clostridium difficile-associated diarrhea in inflammatory bowel disease. J Crohns Colitis 3 (2009), 4–7.
    • (2009) J Crohns Colitis , vol.3 , pp. 4-7
    • Bossuyt, P.1    Verhaegen, J.2    Van Assche, G.3
  • 13
    • 33947105999 scopus 로고    scopus 로고
    • Incidence of Clostridium difficile infection in inflammatory bowel disease
    • 13 Rodemann, J.F., Dubberke, E.R., Reske, K.A., et al. Incidence of Clostridium difficile infection in inflammatory bowel disease. Clin Gastroenterol Hepatol 5 (2007), 339–344.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 339-344
    • Rodemann, J.F.1    Dubberke, E.R.2    Reske, K.A.3
  • 14
    • 84931050069 scopus 로고    scopus 로고
    • Risk factors for Clostridium difficile diarrhea in patients with inflammatory bowel disease
    • 14 Ramos-Martinez, A., Ortiz-Balbuena, J., Curto-Garcia, I., et al. Risk factors for Clostridium difficile diarrhea in patients with inflammatory bowel disease. Rev Esp Enferm Dig 107 (2015), 4–8.
    • (2015) Rev Esp Enferm Dig , vol.107 , pp. 4-8
    • Ramos-Martinez, A.1    Ortiz-Balbuena, J.2    Curto-Garcia, I.3
  • 15
    • 33947111354 scopus 로고    scopus 로고
    • Impact of Clostridium difficile on inflammatory bowel disease
    • 15 Issa, M., Vijayapal, A., Graham, M.B., et al. Impact of Clostridium difficile on inflammatory bowel disease. Clin Gastroenterol Hepatol 5 (2007), 345–351.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 345-351
    • Issa, M.1    Vijayapal, A.2    Graham, M.B.3
  • 16
    • 38549093523 scopus 로고    scopus 로고
    • Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease
    • 16 Ananthakrishnan, A.N., McGinley, E.L., Binion, D.G., Excess hospitalisation burden associated with Clostridium difficile in patients with inflammatory bowel disease. Gut 57 (2008), 205–210.
    • (2008) Gut , vol.57 , pp. 205-210
    • Ananthakrishnan, A.N.1    McGinley, E.L.2    Binion, D.G.3
  • 17
    • 44949261865 scopus 로고    scopus 로고
    • A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients
    • 17 Nguyen, G.C., Kaplan, G.G., Harris, M.L., et al. A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients. Am J Gastroenterol 103 (2008), 1443–1450.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1443-1450
    • Nguyen, G.C.1    Kaplan, G.G.2    Harris, M.L.3
  • 18
    • 84946914195 scopus 로고    scopus 로고
    • Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease
    • 18 Monaghan, T.M., Cockayne, A., Mahida, Y.R., Pathogenesis of Clostridium difficile infection and its potential role in inflammatory bowel disease. Inflamm Bowel Dis 21 (2015), 1957–1966.
    • (2015) Inflamm Bowel Dis , vol.21 , pp. 1957-1966
    • Monaghan, T.M.1    Cockayne, A.2    Mahida, Y.R.3
  • 19
    • 84959144376 scopus 로고    scopus 로고
    • Identification of Medicare recipients at highest risk for Clostridium difficile infection in the US by population attributable risk analysis
    • 19 Dubberke, E.R., Olsen, M.A., Stwalley, D., et al. Identification of Medicare recipients at highest risk for Clostridium difficile infection in the US by population attributable risk analysis. PLoS One, 11, 2016, e0146822.
    • (2016) PLoS One , vol.11 , pp. e0146822
    • Dubberke, E.R.1    Olsen, M.A.2    Stwalley, D.3
  • 20
    • 0034628426 scopus 로고    scopus 로고
    • Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A
    • 20 Kyne, L., Warny, M., Qamar, A., et al. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 342 (2000), 390–397.
    • (2000) N Engl J Med , vol.342 , pp. 390-397
    • Kyne, L.1    Warny, M.2    Qamar, A.3
  • 21
    • 84855416808 scopus 로고    scopus 로고
    • Editorial: not so nosocomial anymore: the growing threat of community-acquired Clostridium difficile
    • 21 Leffler, D.A., Lamont, J.T., Editorial: not so nosocomial anymore: the growing threat of community-acquired Clostridium difficile. Am J Gastroenterol 107 (2012), 96–98.
    • (2012) Am J Gastroenterol , vol.107 , pp. 96-98
    • Leffler, D.A.1    Lamont, J.T.2
  • 22
    • 66949151443 scopus 로고    scopus 로고
    • The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission
    • 22 Clayton, E.M., Rea, M.C., Shanahan, F., et al. The vexed relationship between Clostridium difficile and inflammatory bowel disease: an assessment of carriage in an outpatient setting among patients in remission. Am J Gastroenterol 104 (2009), 1162–1169.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1162-1169
    • Clayton, E.M.1    Rea, M.C.2    Shanahan, F.3
  • 23
    • 84898809123 scopus 로고    scopus 로고
    • The microbiome in inflammatory bowel disease: current status and the future ahead
    • 23 Kostic, A.D., Xavier, R.J., Gevers, D., The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology 146 (2014), 1489–1499.
    • (2014) Gastroenterology , vol.146 , pp. 1489-1499
    • Kostic, A.D.1    Xavier, R.J.2    Gevers, D.3
  • 24
    • 35348857386 scopus 로고    scopus 로고
    • Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
    • 24 Frank, D.N., St Amand, A.L., Feldman, R.A., et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 104 (2007), 13780–13785.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13780-13785
    • Frank, D.N.1    St Amand, A.L.2    Feldman, R.A.3
  • 25
    • 84904048875 scopus 로고    scopus 로고
    • A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis
    • 25 Machiels, K., Joossens, M., Sabino, J., et al. A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis. Gut 63 (2014), 1275–1283.
    • (2014) Gut , vol.63 , pp. 1275-1283
    • Machiels, K.1    Joossens, M.2    Sabino, J.3
  • 26
    • 77649282955 scopus 로고    scopus 로고
    • Metabolism of bile salts in mice influences spore germination in Clostridium difficile
    • 26 Giel, J.L., Sorg, J.A., Sonenshein, A.L., et al. Metabolism of bile salts in mice influences spore germination in Clostridium difficile. PLoS One, 5, 2010, e8740.
    • (2010) PLoS One , vol.5 , pp. e8740
    • Giel, J.L.1    Sorg, J.A.2    Sonenshein, A.L.3
  • 27
    • 84963891450 scopus 로고    scopus 로고
    • Recurrent Clostridium difficile infection associates with distinct bile acid and microbiome profiles
    • 27 Allegretti, J.R., Kearney, S., Li, N., et al. Recurrent Clostridium difficile infection associates with distinct bile acid and microbiome profiles. Aliment Pharmacol Ther 43 (2016), 1142–1153.
    • (2016) Aliment Pharmacol Ther , vol.43 , pp. 1142-1153
    • Allegretti, J.R.1    Kearney, S.2    Li, N.3
  • 28
    • 0035915688 scopus 로고    scopus 로고
    • Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea
    • 28 Kyne, L., Warny, M., Qamar, A., et al. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhoea. Lancet 357 (2001), 189–193.
    • (2001) Lancet , vol.357 , pp. 189-193
    • Kyne, L.1    Warny, M.2    Qamar, A.3
  • 29
    • 74849098405 scopus 로고    scopus 로고
    • Treatment with monoclonal antibodies against Clostridium difficile toxins
    • 29 Lowy, I., Molrine, D.C., Leav, B.A., et al. Treatment with monoclonal antibodies against Clostridium difficile toxins. N Engl J Med 362 (2010), 197–205.
    • (2010) N Engl J Med , vol.362 , pp. 197-205
    • Lowy, I.1    Molrine, D.C.2    Leav, B.A.3
  • 30
    • 76849114352 scopus 로고    scopus 로고
    • Clinical outcomes of patients with ulcerative colitis and co-existing Clostridium difficile infection
    • 30 Jodorkovsky, D., Young, Y., Abreu, M.T., Clinical outcomes of patients with ulcerative colitis and co-existing Clostridium difficile infection. Dig Dis Sci 55 (2010), 415–420.
    • (2010) Dig Dis Sci , vol.55 , pp. 415-420
    • Jodorkovsky, D.1    Young, Y.2    Abreu, M.T.3
  • 31
    • 84861968425 scopus 로고    scopus 로고
    • IBD: poor outcomes after Clostridium difficile infection in IBD
    • 31 Khanna, S., Pardi, D.S., IBD: poor outcomes after Clostridium difficile infection in IBD. Nat Rev Gastroenterol Hepatol 9 (2012), 307–308.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 307-308
    • Khanna, S.1    Pardi, D.S.2
  • 32
    • 62949146399 scopus 로고    scopus 로고
    • Prospective derivation and validation of a clinical prediction rule for recurrent Clostridium difficile infection
    • 32 Hu, M.Y., Katchar, K., Kyne, L., et al. Prospective derivation and validation of a clinical prediction rule for recurrent Clostridium difficile infection. Gastroenterology 136 (2009), 1206–1214.
    • (2009) Gastroenterology , vol.136 , pp. 1206-1214
    • Hu, M.Y.1    Katchar, K.2    Kyne, L.3
  • 33
    • 84868546746 scopus 로고    scopus 로고
    • Can we identify patients at high risk of recurrent Clostridium difficile infection?
    • 33 Kelly, C.P., Can we identify patients at high risk of recurrent Clostridium difficile infection?. Clin Microbiol Infect 18:Suppl 6 (2012), 21–27.
    • (2012) Clin Microbiol Infect , vol.18 , pp. 21-27
    • Kelly, C.P.1
  • 34
    • 56249107224 scopus 로고    scopus 로고
    • Meta-analysis to assess risk factors for recurrent Clostridium difficile infection
    • 34 Garey, K.W., Sethi, S., Yadav, Y., et al. Meta-analysis to assess risk factors for recurrent Clostridium difficile infection. J Hosp Infect 70 (2008), 298–304.
    • (2008) J Hosp Infect , vol.70 , pp. 298-304
    • Garey, K.W.1    Sethi, S.2    Yadav, Y.3
  • 35
    • 84970004349 scopus 로고    scopus 로고
    • Recurrence of Clostridium difficile infection in patients with inflammatory bowel disease: the RECIDIVISM study
    • 35 Razik, R., Rumman, A., Bahreini, Z., et al. Recurrence of Clostridium difficile infection in patients with inflammatory bowel disease: the RECIDIVISM study. Am J Gastroenterol 111 (2016), 1141–1146.
    • (2016) Am J Gastroenterol , vol.111 , pp. 1141-1146
    • Razik, R.1    Rumman, A.2    Bahreini, Z.3
  • 36
    • 84875952150 scopus 로고    scopus 로고
    • Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections
    • quiz 99
    • 36 Surawicz, C.M., Brandt, L.J., Binion, D.G., et al. Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol 108 (2013), 478–498 quiz 99.
    • (2013) Am J Gastroenterol , vol.108 , pp. 478-498
    • Surawicz, C.M.1    Brandt, L.J.2    Binion, D.G.3
  • 37
    • 84887259304 scopus 로고    scopus 로고
    • European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection
    • 37 Debast, S.B., Bauer, M.P., Kuijper, E.J., et al. European Society of Clinical Microbiology and Infectious Diseases: update of the treatment guidance document for Clostridium difficile infection. Clin Microbiol Infect 20:Suppl 2 (2014), 1–26.
    • (2014) Clin Microbiol Infect , vol.20 , pp. 1-26
    • Debast, S.B.1    Bauer, M.P.2    Kuijper, E.J.3
  • 38
    • 34848846245 scopus 로고    scopus 로고
    • Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents
    • 38 Riggs, M.M., Sethi, A.K., Zabarsky, T.F., et al. Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin Infect Dis 45 (2007), 992–998.
    • (2007) Clin Infect Dis , vol.45 , pp. 992-998
    • Riggs, M.M.1    Sethi, A.K.2    Zabarsky, T.F.3
  • 39
    • 84963620243 scopus 로고    scopus 로고
    • Asymptomatic Clostridium difficile colonization: epidemiology and clinical implications
    • 39 Furuya-Kanamori, L., Marquess, J., Yakob, L., et al. Asymptomatic Clostridium difficile colonization: epidemiology and clinical implications. BMC Infect Dis, 15, 2015, 516.
    • (2015) BMC Infect Dis , vol.15 , pp. 516
    • Furuya-Kanamori, L.1    Marquess, J.2    Yakob, L.3
  • 40
    • 84903950312 scopus 로고    scopus 로고
    • Prevalence and risk factors for asymptomatic Clostridium difficile carriage
    • 40 Alasmari, F., Seiler, S.M., Hink, T., et al. Prevalence and risk factors for asymptomatic Clostridium difficile carriage. Clin Infect Dis 59 (2014), 216–222.
    • (2014) Clin Infect Dis , vol.59 , pp. 216-222
    • Alasmari, F.1    Seiler, S.M.2    Hink, T.3
  • 41
    • 84885955622 scopus 로고    scopus 로고
    • Differences in outcome according to Clostridium difficile testing method: a prospective multicentre diagnostic validation study of C difficile infection
    • 41 Planche, T.D., Davies, K.A., Coen, P.G., et al. Differences in outcome according to Clostridium difficile testing method: a prospective multicentre diagnostic validation study of C difficile infection. Lancet Infect Dis 13 (2013), 936–945.
    • (2013) Lancet Infect Dis , vol.13 , pp. 936-945
    • Planche, T.D.1    Davies, K.A.2    Coen, P.G.3
  • 42
    • 84946147732 scopus 로고    scopus 로고
    • Overdiagnosis of Clostridium difficile infection in the molecular test era
    • 42 Polage, C.R., Gyorke, C.E., Kennedy, M.A., et al. Overdiagnosis of Clostridium difficile infection in the molecular test era. JAMA Intern Med 175 (2015), 1792–1801.
    • (2015) JAMA Intern Med , vol.175 , pp. 1792-1801
    • Polage, C.R.1    Gyorke, C.E.2    Kennedy, M.A.3
  • 43
    • 84875952150 scopus 로고    scopus 로고
    • Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections
    • 43 Surawicz, C.M., Brandt, L.J., Binion, D.G., et al. Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections. Am J Gastroenterol 108 (2013), 478–498.
    • (2013) Am J Gastroenterol , vol.108 , pp. 478-498
    • Surawicz, C.M.1    Brandt, L.J.2    Binion, D.G.3
  • 44
    • 34547133720 scopus 로고    scopus 로고
    • A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity
    • 44 Zar, F.A., Bakkanagari, S.R., Moorthi, K.M., et al. A comparison of vancomycin and metronidazole for the treatment of Clostridium difficile-associated diarrhea, stratified by disease severity. Clin Infect Dis 45 (2007), 302–307.
    • (2007) Clin Infect Dis , vol.45 , pp. 302-307
    • Zar, F.A.1    Bakkanagari, S.R.2    Moorthi, K.M.3
  • 45
    • 19344363493 scopus 로고    scopus 로고
    • Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada
    • 45 Pepin, J., Alary, M.E., Valiquette, L., et al. Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada. Clin Infect Dis 40 (2005), 1591–1597.
    • (2005) Clin Infect Dis , vol.40 , pp. 1591-1597
    • Pepin, J.1    Alary, M.E.2    Valiquette, L.3
  • 46
    • 19344364596 scopus 로고    scopus 로고
    • Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole
    • 46 Musher, D.M., Aslam, S., Logan, N., et al. Relatively poor outcome after treatment of Clostridium difficile colitis with metronidazole. Clin Infect Dis 40 (2005), 1586–1590.
    • (2005) Clin Infect Dis , vol.40 , pp. 1586-1590
    • Musher, D.M.1    Aslam, S.2    Logan, N.3
  • 47
    • 84905057299 scopus 로고    scopus 로고
    • Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials
    • 47 Johnson, S., Louie, T.J., Gerding, D.N., et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin Infect Dis 59 (2014), 345–354.
    • (2014) Clin Infect Dis , vol.59 , pp. 345-354
    • Johnson, S.1    Louie, T.J.2    Gerding, D.N.3
  • 48
    • 79551527297 scopus 로고    scopus 로고
    • Fidaxomicin versus vancomycin for Clostridium difficile infection
    • 48 Louie, T.J., Miller, M.A., Mullane, K.M., et al. Fidaxomicin versus vancomycin for Clostridium difficile infection. N Engl J Med 364 (2011), 422–431.
    • (2011) N Engl J Med , vol.364 , pp. 422-431
    • Louie, T.J.1    Miller, M.A.2    Mullane, K.M.3
  • 49
    • 80051957059 scopus 로고    scopus 로고
    • Efficacy of fidaxomicin versus vancomycin as therapy for Clostridium difficile infection in individuals taking concomitant antibiotics for other concurrent infections
    • 49 Mullane, K.M., Miller, M.A., Weiss, K., et al. Efficacy of fidaxomicin versus vancomycin as therapy for Clostridium difficile infection in individuals taking concomitant antibiotics for other concurrent infections. Clin Infect Dis 53 (2011), 440–447.
    • (2011) Clin Infect Dis , vol.53 , pp. 440-447
    • Mullane, K.M.1    Miller, M.A.2    Weiss, K.3
  • 50
    • 84880944583 scopus 로고    scopus 로고
    • Is fidaxomicin worth the cost? An economic analysis
    • 50 Bartsch, S.M., Umscheid, C.A., Fishman, N., et al. Is fidaxomicin worth the cost? An economic analysis. Clin Infect Dis 57 (2013), 555–561.
    • (2013) Clin Infect Dis , vol.57 , pp. 555-561
    • Bartsch, S.M.1    Umscheid, C.A.2    Fishman, N.3
  • 51
    • 84906092884 scopus 로고    scopus 로고
    • Antibiotics for treatment of Clostridium difficile infection in hospitalized patients with inflammatory bowel disease
    • 51 Horton, H.A., Dezfoli, S., Berel, D., et al. Antibiotics for treatment of Clostridium difficile infection in hospitalized patients with inflammatory bowel disease. Antimicrob Agents Chemother 58 (2014), 5054–5059.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 5054-5059
    • Horton, H.A.1    Dezfoli, S.2    Berel, D.3
  • 52
    • 85026330864 scopus 로고    scopus 로고
    • Outcomes of fidaxomicin treatment of Clostridium difficile infection
    • 52 Spiceland, C., Khanna, S., Pardi, D.S., Outcomes of fidaxomicin treatment of Clostridium difficile infection. Gastroenterology, 150, 2015, S744.
    • (2015) Gastroenterology , vol.150 , pp. S744
    • Spiceland, C.1    Khanna, S.2    Pardi, D.S.3
  • 53
    • 79956076630 scopus 로고    scopus 로고
    • Increased health burden associated with Clostridium difficile diarrhoea in patients with inflammatory bowel disease
    • 53 Jen, M.H., Saxena, S., Bottle, A., et al. Increased health burden associated with Clostridium difficile diarrhoea in patients with inflammatory bowel disease. Aliment Pharmacol Ther 33 (2011), 1322–1331.
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1322-1331
    • Jen, M.H.1    Saxena, S.2    Bottle, A.3
  • 54
    • 84931295496 scopus 로고    scopus 로고
    • Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook
    • 54 Kelly, C.R., Kahn, S., Kashyap, P., et al. Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook. Gastroenterology 149 (2015), 223–237.
    • (2015) Gastroenterology , vol.149 , pp. 223-237
    • Kelly, C.R.1    Kahn, S.2    Kashyap, P.3
  • 55
    • 84858146907 scopus 로고    scopus 로고
    • Current strategies for management of initial Clostridium difficile infection
    • 55 Kelly, C.P., Current strategies for management of initial Clostridium difficile infection. J Hosp Med 7:Suppl 3 (2012), S5–S10.
    • (2012) J Hosp Med , vol.7 , pp. S5-S10
    • Kelly, C.P.1
  • 56
    • 84903894091 scopus 로고    scopus 로고
    • Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients
    • 56 Kelly, C.R., Ihunnah, C., Fischer, M., et al. Fecal microbiota transplant for treatment of Clostridium difficile infection in immunocompromised patients. Am J Gastroenterol 109 (2014), 1065–1671.
    • (2014) Am J Gastroenterol , vol.109 , pp. 1065-1671
    • Kelly, C.R.1    Ihunnah, C.2    Fischer, M.3
  • 57
    • 84964765013 scopus 로고    scopus 로고
    • Inflammatory bowel disease affects the outcome of fecal microbiota transplantation for recurrent Clostridium difficile infection
    • 57 Khoruts, A., Rank, K.M., Newman, K.M., et al. Inflammatory bowel disease affects the outcome of fecal microbiota transplantation for recurrent Clostridium difficile infection. Clin Gastroenterol Hepatol 14 (2016), 1433–1438.
    • (2016) Clin Gastroenterol Hepatol , vol.14 , pp. 1433-1438
    • Khoruts, A.1    Rank, K.M.2    Newman, K.M.3
  • 58
    • 84966293687 scopus 로고    scopus 로고
    • Donor species richness determines faecal microbiota transplantation success in inflammatory bowel disease
    • 58 Vermeire, S., Joossens, M., Verbeke, K., et al. Donor species richness determines faecal microbiota transplantation success in inflammatory bowel disease. J Crohns Colitis 10 (2016), 387–394.
    • (2016) J Crohns Colitis , vol.10 , pp. 387-394
    • Vermeire, S.1    Joossens, M.2    Verbeke, K.3
  • 59
    • 69249181666 scopus 로고    scopus 로고
    • Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and clostridium difficile infection
    • 59 Ben-Horin, S., Margalit, M., Bossuyt, P., et al. Combination immunomodulator and antibiotic treatment in patients with inflammatory bowel disease and clostridium difficile infection. Clin Gastroenterol Hepatol 7 (2009), 981–987.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 981-987
    • Ben-Horin, S.1    Margalit, M.2    Bossuyt, P.3
  • 60
    • 84858284133 scopus 로고    scopus 로고
    • Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease
    • 60 Ananthakrishnan, A.N., Guzman-Perez, R., Gainer, V., et al. Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease. Aliment Pharmacol Ther 35 (2012), 789–795.
    • (2012) Aliment Pharmacol Ther , vol.35 , pp. 789-795
    • Ananthakrishnan, A.N.1    Guzman-Perez, R.2    Gainer, V.3
  • 61
    • 79958795293 scopus 로고    scopus 로고
    • Practice of gastroenterologists in treating flaring inflammatory bowel disease patients with clostridium difficile: antibiotics alone or combined antibiotics/immunomodulators?
    • 61 Yanai, H., Nguyen, G.C., Yun, L., et al. Practice of gastroenterologists in treating flaring inflammatory bowel disease patients with clostridium difficile: antibiotics alone or combined antibiotics/immunomodulators?. Inflamm Bowel Dis 17 (2011), 1540–1546.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1540-1546
    • Yanai, H.1    Nguyen, G.C.2    Yun, L.3
  • 62
    • 58849142243 scopus 로고    scopus 로고
    • Clostridium difficile and inflammatory bowel disease
    • 62 Issa, M., Ananthakrishnan, A.N., Binion, D.G., Clostridium difficile and inflammatory bowel disease. Inflamm Bowel Dis 14 (2008), 1432–1442.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1432-1442
    • Issa, M.1    Ananthakrishnan, A.N.2    Binion, D.G.3
  • 63
    • 70449488916 scopus 로고    scopus 로고
    • Therapy- and non-therapy-dependent infectious complications in inflammatory bowel disease
    • 63 Epple, H.J., Therapy- and non-therapy-dependent infectious complications in inflammatory bowel disease. Dig Dis 27 (2009), 555–559.
    • (2009) Dig Dis , vol.27 , pp. 555-559
    • Epple, H.J.1


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