Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 2, 2017, Pages 298-303

  Aguirre, Jacob D ^a   Dunkerley, Karen M ^a   Mercier, Pascal ^a   Shaw, Gary S ^a  

^a WESTERN UNIVERSITY   (Canada)

Author keywords

Conformational change; E3 ligase; Parkinson's disease; Phosphorylation; Ubiquitin

Indexed keywords

PARKIN; PHOSPHOSERINE; PROTEIN KINASE; PTEN INDUCED KINASE 1; UBIQUITIN; UNCLASSIFIED DRUG; PROTEIN BINDING; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

CONFERENCE PAPER; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; HUMAN; MITOPHAGY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; STATIC ELECTRICITY; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

HUMANS; MUTATION; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN BINDING; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 85009266835     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1613040114     Document Type: Article

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