메뉴 건너뛰기




Volumn 344, Issue , 2017, Pages 1-14

Medullary 5-HT neurons: Switch from tonic respiratory drive to chemoreception during postnatal development

Author keywords

chemoreception; Lmx1b; respiratory; serotonin

Indexed keywords

ACIDOSIS; ADULT; AMBIENT AIR; ANIMAL CELL; ARTICLE; BREATHING; CELL CULTURE; CELL MATURATION; CHEMORECEPTOR; CHEMOSENSITIVITY; CONTROLLED STUDY; GENE EXPRESSION; GROWTH RATE; HYPERCAPNIC VENTILATORY RESPONSE; HYPEROXIA; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MORTALITY; MOUSE; NEWBORN; NONHUMAN; PATCH CLAMP TECHNIQUE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REPORTER GENE; RESPIRATORY TRACT PARAMETERS; SEROTONINERGIC NERVE CELL; SEROTONINERGIC SYSTEM; SURVIVAL RATE; ACTION POTENTIAL; ANIMAL; BODY PLETHYSMOGRAPHY; CHEMORECEPTOR CELL; GENETICS; GROWTH, DEVELOPMENT AND AGING; MEDULLA OBLONGATA; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

EID: 85008879520     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2016.09.002     Document Type: Article
Times cited : (26)

References (81)
  • 1
    • 85008880368 scopus 로고    scopus 로고
    • C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with the sympathetic outflow
    • Abbott, S.B., Kanbar, R., Coates, M.B., Stornetta, R.J., Guyenet, P.G., C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with the sympathetic outflow. Faseb J, 25, 2011.
    • (2011) Faseb J , vol.25
    • Abbott, S.B.1    Kanbar, R.2    Coates, M.B.3    Stornetta, R.J.4    Guyenet, P.G.5
  • 3
    • 0029995042 scopus 로고    scopus 로고
    • Serotonergic and noradrenergic effects on respiratory neural discharge in the medullary slice preparation of neonatal rats
    • Al-Zubaidy, Z.A., Erickson, R.L., Greer, J.J., Serotonergic and noradrenergic effects on respiratory neural discharge in the medullary slice preparation of neonatal rats. Pflugers Arch Eur J Physiol 431:6 (1996), 942–949.
    • (1996) Pflugers Arch Eur J Physiol , vol.431 , Issue.6 , pp. 942-949
    • Al-Zubaidy, Z.A.1    Erickson, R.L.2    Greer, J.J.3
  • 5
    • 0030273282 scopus 로고    scopus 로고
    • Effect of nicotine exposure on postnatal ventilatory responses to hypoxia and hypercapnia
    • Bamford, O.S., Schuen, J.N., Carroll, J.L., Effect of nicotine exposure on postnatal ventilatory responses to hypoxia and hypercapnia. Respir Physiol 106:1 (1996), 1–11.
    • (1996) Respir Physiol , vol.106 , Issue.1 , pp. 1-11
    • Bamford, O.S.1    Schuen, J.N.2    Carroll, J.L.3
  • 6
    • 0012463405 scopus 로고    scopus 로고
    • Types of Nerve Cell Cultures, Their Advantages and Limitations
    • G. Banker K. Goslin Second ed. MIT Press Cambridge, MA
    • Banker, G., Goslin, K., Types of Nerve Cell Cultures, Their Advantages and Limitations. Banker, G., Goslin, K., (eds.) Culturing Nerve Cells, Second ed., 1998, MIT Press, Cambridge, MA, 11–35.
    • (1998) Culturing Nerve Cells , pp. 11-35
    • Banker, G.1    Goslin, K.2
  • 7
    • 1842377995 scopus 로고    scopus 로고
    • Effects of serotonin on caudal raphe neurons: Activation of an inwardly rectifying potassium conductance
    • Bayliss, D.A., Li, Y.W., Talley, E.M., Effects of serotonin on caudal raphe neurons: Activation of an inwardly rectifying potassium conductance. J Neurophysiol 77:3 (1997), 1349–1361.
    • (1997) J Neurophysiol , vol.77 , Issue.3 , pp. 1349-1361
    • Bayliss, D.A.1    Li, Y.W.2    Talley, E.M.3
  • 8
    • 0029014109 scopus 로고
    • Inhibition of N-Type and P-Type calcium currents and the after hyperpolarization in rat motoneurons by serotonin
    • Bayliss, D.A., Umemiya, M., Berger, A.J., Inhibition of N-Type and P-Type calcium currents and the after hyperpolarization in rat motoneurons by serotonin. J Physiol 485:3 (1995), 635–647.
    • (1995) J Physiol , vol.485 , Issue.3 , pp. 635-647
    • Bayliss, D.A.1    Umemiya, M.2    Berger, A.J.3
  • 10
    • 0030050524 scopus 로고    scopus 로고
    • Evidence for central chemoreception in the midline raphe
    • Bernard, D.G., Li, A.H., Nattie, E.E., Evidence for central chemoreception in the midline raphe. J Appl Physiol 80:1 (1996), 108–115.
    • (1996) J Appl Physiol , vol.80 , Issue.1 , pp. 108-115
    • Bernard, D.G.1    Li, A.H.2    Nattie, E.E.3
  • 11
    • 25444528434 scopus 로고    scopus 로고
    • Hypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65)
    • Bissonnette, J.M., Knopp, S.J., Hypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65). Respir Res, 5, 2004, 3.
    • (2004) Respir Res , vol.5 , pp. 3
    • Bissonnette, J.M.1    Knopp, S.J.2
  • 14
    • 84919876035 scopus 로고    scopus 로고
    • Functional and developmental identification of a molecular subtype of brain serotonergic neuron specialized to regulate breathing dynamics
    • Brust, R.D., Corcoran, A.E., Richerson, G.B., Nattie, E., Dymecki, S.M., Functional and developmental identification of a molecular subtype of brain serotonergic neuron specialized to regulate breathing dynamics. Cell Rep 9:6 (2014), 2152–2165.
    • (2014) Cell Rep , vol.9 , Issue.6 , pp. 2152-2165
    • Brust, R.D.1    Corcoran, A.E.2    Richerson, G.B.3    Nattie, E.4    Dymecki, S.M.5
  • 15
    • 84907487062 scopus 로고    scopus 로고
    • Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception
    • Cerpa, V., Gonzalez, A., Richerson, G.B., Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception. Neuroscience 279 (2014), 65–76.
    • (2014) Neuroscience , vol.279 , pp. 65-76
    • Cerpa, V.1    Gonzalez, A.2    Richerson, G.B.3
  • 17
    • 80054978974 scopus 로고    scopus 로고
    • Postnatal loss of brainstem serotonin neurones compromises the ability of neonatal rats to survive episodic severe hypoxia
    • Cummings, K.J., Hewitt, J.C., Li, A., Daubenspeck, J.A., Nattie, E.E., Postnatal loss of brainstem serotonin neurones compromises the ability of neonatal rats to survive episodic severe hypoxia. J Physiol 589:Pt 21 (2011), 5247–5256.
    • (2011) J Physiol , vol.589 , pp. 5247-5256
    • Cummings, K.J.1    Hewitt, J.C.2    Li, A.3    Daubenspeck, J.A.4    Nattie, E.E.5
  • 18
    • 77951763419 scopus 로고    scopus 로고
    • Bradycardia in serotonin-deficient Pet-1(-/-) mice: influence of respiratory dysfunction and hyperthermia over the first 2 postnatal weeks
    • Cummings, K.J., Li, A., Deneris, E.S., Nattie, E.E., Bradycardia in serotonin-deficient Pet-1(-/-) mice: influence of respiratory dysfunction and hyperthermia over the first 2 postnatal weeks. Am J Physiol Regul Integr Comp Physiol 298:5 (2010), R1333–R1342.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298 , Issue.5 , pp. R1333-R1342
    • Cummings, K.J.1    Li, A.2    Deneris, E.S.3    Nattie, E.E.4
  • 20
    • 0025293089 scopus 로고
    • Depolarization and stimulation of neurons in nucleus tractus solitarii by carbon dioxide does not require chemical synaptic input
    • Dean, J.B., Bayliss, D.A., Erickson, J.T., Lawing, W.L., Millhorn, D.E., Depolarization and stimulation of neurons in nucleus tractus solitarii by carbon dioxide does not require chemical synaptic input. Neuroscience 36:1 (1990), 207–216.
    • (1990) Neuroscience , vol.36 , Issue.1 , pp. 207-216
    • Dean, J.B.1    Bayliss, D.A.2    Erickson, J.T.3    Lawing, W.L.4    Millhorn, D.E.5
  • 21
    • 79951522470 scopus 로고    scopus 로고
    • Control of breathing by raphe obscurus serotonergic neurons in mice
    • DePuy, S.D., Kanbar, R., Coates, M.B., Stornetta, R.L., Guyenet, P.G., Control of breathing by raphe obscurus serotonergic neurons in mice. J Neurosci 31:6 (2011), 1981–1990.
    • (2011) J Neurosci , vol.31 , Issue.6 , pp. 1981-1990
    • DePuy, S.D.1    Kanbar, R.2    Coates, M.B.3    Stornetta, R.L.4    Guyenet, P.G.5
  • 22
    • 0002834878 scopus 로고
    • A barometric method for measuring ventilation in newborn infants
    • Drorbaugh, J.E., Fenn, W.O., A barometric method for measuring ventilation in newborn infants. Pediatrics 16:1 (1955), 81–87.
    • (1955) Pediatrics , vol.16 , Issue.1 , pp. 81-87
    • Drorbaugh, J.E.1    Fenn, W.O.2
  • 24
    • 0032848638 scopus 로고    scopus 로고
    • Nucleus ambiguus and bulbospinal ventral respiratory group neurons in the neonatal rat
    • Ellenberger, H.H., Nucleus ambiguus and bulbospinal ventral respiratory group neurons in the neonatal rat. Brain Res Bull 50:1 (1999), 1–13.
    • (1999) Brain Res Bull , vol.50 , Issue.1 , pp. 1-13
    • Ellenberger, H.H.1
  • 25
    • 34548828248 scopus 로고    scopus 로고
    • Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges
    • Erickson, J.T., Shafer, G., Rossetti, M.D., Wilson, C.G., Deneris, E.S., Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges. Respir Physiol Neurobiol 159:1 (2007), 85–101.
    • (2007) Respir Physiol Neurobiol , vol.159 , Issue.1 , pp. 85-101
    • Erickson, J.T.1    Shafer, G.2    Rossetti, M.D.3    Wilson, C.G.4    Deneris, E.S.5
  • 26
    • 58149401177 scopus 로고    scopus 로고
    • Prenatal to early postnatal nicotine exposure impairs central chemoreception and modifies breathing pattern in mouse neonates: A probable link to sudden infant death syndrome
    • Eugenin, J., Otarola, M., Bravo, E., Coddou, C., Cerpa, V., Reyes-Parada, M., Llona, I., von Bernhardi, R., Prenatal to early postnatal nicotine exposure impairs central chemoreception and modifies breathing pattern in mouse neonates: A probable link to sudden infant death syndrome. J Neurosci 28:51 (2008), 13907–13917.
    • (2008) J Neurosci , vol.28 , Issue.51 , pp. 13907-13917
    • Eugenin, J.1    Otarola, M.2    Bravo, E.3    Coddou, C.4    Cerpa, V.5    Reyes-Parada, M.6    Llona, I.7    von Bernhardi, R.8
  • 27
    • 0037586422 scopus 로고    scopus 로고
    • Breathing: rhythmicity, plasticity, chemosensitivity
    • Feldman, J.L., Mitchell, G.S., Nattie, E.E., Breathing: rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci 26 (2003), 239–266.
    • (2003) Annu Rev Neurosci , vol.26 , pp. 239-266
    • Feldman, J.L.1    Mitchell, G.S.2    Nattie, E.E.3
  • 29
    • 56449121657 scopus 로고    scopus 로고
    • Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons
    • Hodges, M.R., Richerson, G.B., Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons. Respir Physiol Neurobiol 164:3 (2008), 350–357.
    • (2008) Respir Physiol Neurobiol , vol.164 , Issue.3 , pp. 350-357
    • Hodges, M.R.1    Richerson, G.B.2
  • 30
    • 77957016202 scopus 로고    scopus 로고
    • Medullary serotonin neurons and their roles in central respiratory chemoreception
    • Hodges, M.R., Richerson, G.B., Medullary serotonin neurons and their roles in central respiratory chemoreception. Respir Physiol Neurobiol 173:3 (2010), 256–263.
    • (2010) Respir Physiol Neurobiol , vol.173 , Issue.3 , pp. 256-263
    • Hodges, M.R.1    Richerson, G.B.2
  • 31
    • 77951972560 scopus 로고    scopus 로고
    • 2 chemoreception, and thermoregulation
    • 2 chemoreception, and thermoregulation. J Appl Physiol 108:5 (2010), 1425–1432.
    • (2010) J Appl Physiol , vol.108 , Issue.5 , pp. 1425-1432
    • Hodges, M.R.1    Richerson, G.B.2
  • 33
    • 69049111812 scopus 로고    scopus 로고
    • Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development
    • Hodges, M.R., Wehner, M., Aungst, J., Smith, J.C., Richerson, G.B., Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development. J Neurosci 29:33 (2009), 10341–10349.
    • (2009) J Neurosci , vol.29 , Issue.33 , pp. 10341-10349
    • Hodges, M.R.1    Wehner, M.2    Aungst, J.3    Smith, J.C.4    Richerson, G.B.5
  • 34
    • 0242391960 scopus 로고    scopus 로고
    • Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression
    • Holmes, A., Murphy, D.L., Crawley, J.N., Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression. Biol Psychiatry 54:10 (2003), 953–959.
    • (2003) Biol Psychiatry , vol.54 , Issue.10 , pp. 953-959
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 35
    • 0023812645 scopus 로고
    • Immunohistochemical localization of serotonin-containing and substance P-containing fibers around respiratory muscle motoneurons in the nucleus ambiguus of the cat
    • Holtman, J.R., Immunohistochemical localization of serotonin-containing and substance P-containing fibers around respiratory muscle motoneurons in the nucleus ambiguus of the cat. Neuroscience 26:1 (1988), 169–178.
    • (1988) Neuroscience , vol.26 , Issue.1 , pp. 169-178
    • Holtman, J.R.1
  • 36
    • 0022635613 scopus 로고
    • Effect of electrical and chemical-stimulation of the raphe obscurus on phrenic-nerve activity in the cat
    • Holtman, J.R., Anastasi, N.C., Norman, W.P., Dretchen, K.L., Effect of electrical and chemical-stimulation of the raphe obscurus on phrenic-nerve activity in the cat. Brain Res 362:2 (1986), 214–220.
    • (1986) Brain Res , vol.362 , Issue.2 , pp. 214-220
    • Holtman, J.R.1    Anastasi, N.C.2    Norman, W.P.3    Dretchen, K.L.4
  • 37
    • 0025170678 scopus 로고
    • Origin of serotonin-containing projections to the ventral respiratory group in the rat
    • Holtman, J.R., Marion, L.J., Speck, D.F., Origin of serotonin-containing projections to the ventral respiratory group in the rat. Neuroscience 37:2 (1990), 541–552.
    • (1990) Neuroscience , vol.37 , Issue.2 , pp. 541-552
    • Holtman, J.R.1    Marion, L.J.2    Speck, D.F.3
  • 38
    • 22344433287 scopus 로고    scopus 로고
    • Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats
    • Johnson, P.L., Hollis, J.H., Moratalla, R., Lightman, S.L., Lowry, C.A., Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats. J Psychopharmacol 19:4 (2005), 327–341.
    • (2005) J Psychopharmacol , vol.19 , Issue.4 , pp. 327-341
    • Johnson, P.L.1    Hollis, J.H.2    Moratalla, R.3    Lightman, S.L.4    Lowry, C.A.5
  • 43
    • 69049117328 scopus 로고    scopus 로고
    • MEDICAL PROGRESS The sudden infant death syndrome
    • Kinney, H.C., Thach, B.T., MEDICAL PROGRESS The sudden infant death syndrome. N Engl J Med 361:8 (2009), 795–805.
    • (2009) N Engl J Med , vol.361 , Issue.8 , pp. 795-805
    • Kinney, H.C.1    Thach, B.T.2
  • 45
    • 0031055045 scopus 로고    scopus 로고
    • Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons
    • Lalley, P.M., Benacka, R., Bischoff, A.M., Richter, D.W., Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons. Brain Res 747:1 (1997), 156–159.
    • (1997) Brain Res , vol.747 , Issue.1 , pp. 156-159
    • Lalley, P.M.1    Benacka, R.2    Bischoff, A.M.3    Richter, D.W.4
  • 46
    • 0010351249 scopus 로고
    • Environmental Influences on the Development of Sympathetic Neurons
    • J. Bottenstein G. Sato Springer US
    • Landis, S., Environmental Influences on the Development of Sympathetic Neurons. Bottenstein, J., Sato, G., (eds.) Cell Culture in the Neurosciences, 1985, Springer, US, 169–192.
    • (1985) Cell Culture in the Neurosciences , pp. 169-192
    • Landis, S.1
  • 47
    • 42949136397 scopus 로고    scopus 로고
    • Serotonin transporter knockout mice have a reduced ventilatory response to hypercapnia (predominantly in males) but not to hypoxia
    • Li, A., Nattie, E., Serotonin transporter knockout mice have a reduced ventilatory response to hypercapnia (predominantly in males) but not to hypoxia. J Physiol 586:9 (2008), 2321–2329.
    • (2008) J Physiol , vol.586 , Issue.9 , pp. 2321-2329
    • Li, A.1    Nattie, E.2
  • 48
    • 38449118278 scopus 로고    scopus 로고
    • Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism
    • Mulkey, D.K., Rosin, D.L., West, G., Takakura, A.C., Moreira, T.S., Bayliss, D.A., Guyenet, P.G., Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. J Neurosci 27:51 (2007), 14128–14138.
    • (2007) J Neurosci , vol.27 , Issue.51 , pp. 14128-14138
    • Mulkey, D.K.1    Rosin, D.L.2    West, G.3    Takakura, A.C.4    Moreira, T.S.5    Bayliss, D.A.6    Guyenet, P.G.7
  • 50
    • 38449084123 scopus 로고    scopus 로고
    • TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity
    • Mulkey, D.K., Talley, E.M., Stornetta, R.L., Siegel, A.R., West, G.H., Chen, X., Sen, N., Mistry, A.M., Guyenet, P.G., Bayliss, D.A., TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. J Neurosci 27:51 (2007), 14049–14058.
    • (2007) J Neurosci , vol.27 , Issue.51 , pp. 14049-14058
    • Mulkey, D.K.1    Talley, E.M.2    Stornetta, R.L.3    Siegel, A.R.4    West, G.H.5    Chen, X.6    Sen, N.7    Mistry, A.M.8    Guyenet, P.G.9    Bayliss, D.A.10
  • 51
    • 1942485936 scopus 로고    scopus 로고
    • Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo
    • Nattie, E.E., Li, A., Richerson, G.B., Lappi, D.A., Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556:Pt 1 (2004), 235–253.
    • (2004) J Physiol , vol.556 , pp. 235-253
    • Nattie, E.E.1    Li, A.2    Richerson, G.B.3    Lappi, D.A.4
  • 52
    • 79960618469 scopus 로고    scopus 로고
    • Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network
    • Niebert, M., Vogelgesang, S., Koch, U.R., Bischoff, A.M., Kron, M., Bock, N., Manzke, T., Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network. PLoS One, 6(7), 2011, e21395.
    • (2011) PLoS One , vol.6 , Issue.7
    • Niebert, M.1    Vogelgesang, S.2    Koch, U.R.3    Bischoff, A.M.4    Kron, M.5    Bock, N.6    Manzke, T.7
  • 53
    • 0036348193 scopus 로고    scopus 로고
    • Alteration of serotonergic receptors in the brain stems of human patients with respiratory disorders
    • Ozawa, Y., Okado, N., Alteration of serotonergic receptors in the brain stems of human patients with respiratory disorders. Neuropediatrics 33:3 (2002), 142–149.
    • (2002) Neuropediatrics , vol.33 , Issue.3 , pp. 142-149
    • Ozawa, Y.1    Okado, N.2
  • 56
    • 0037114964 scopus 로고    scopus 로고
    • Endogenous activation of serotonin-2A receptors is required for respiratory rhythm generation in vitro
    • Pena, F., Ramirez, J.M., Endogenous activation of serotonin-2A receptors is required for respiratory rhythm generation in vitro. J Neurosci 22:24 (2002), 11055–11064.
    • (2002) J Neurosci , vol.22 , Issue.24 , pp. 11055-11064
    • Pena, F.1    Ramirez, J.M.2
  • 57
  • 58
    • 0031550622 scopus 로고    scopus 로고
    • Carbon dioxide regulates the tonic activity of locus coeruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current
    • Pineda, J., Aghajanian, G.K., Carbon dioxide regulates the tonic activity of locus coeruleus neurons by modulating a proton- and polyamine-sensitive inward rectifier potassium current. Neuroscience 77:3 (1997), 723–743.
    • (1997) Neuroscience , vol.77 , Issue.3 , pp. 723-743
    • Pineda, J.1    Aghajanian, G.K.2
  • 59
    • 64849101288 scopus 로고    scopus 로고
    • Raphe neurons stimulate respiratory circuit activity by multiple mechanisms via endogenously released serotonin and substance P
    • Ptak, K., Yamanishi, T., Aungst, J., Milescu, L.S., Zhang, R., Richerson, G.B., Smith, J.C., Raphe neurons stimulate respiratory circuit activity by multiple mechanisms via endogenously released serotonin and substance P. J Neurosci 29:12 (2009), 3720–3737.
    • (2009) J Neurosci , vol.29 , Issue.12 , pp. 3720-3737
    • Ptak, K.1    Yamanishi, T.2    Aungst, J.3    Milescu, L.S.4    Zhang, R.5    Richerson, G.B.6    Smith, J.C.7
  • 62
    • 36048986271 scopus 로고    scopus 로고
    • Effects of temperature on ventilatory response to hypercapnia in newborn mice heterozygous for transcription factor Phox2b
    • Ramanantsoa, N., Vaubourg, V., Matrot, B., Vardon, G., Dauger, S., Gallego, J., Effects of temperature on ventilatory response to hypercapnia in newborn mice heterozygous for transcription factor Phox2b. Am J Physiol Regul Integr Comp Physiol 293:5 (2007), R2027–2035.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , Issue.5 , pp. R2027-2035
    • Ramanantsoa, N.1    Vaubourg, V.2    Matrot, B.3    Vardon, G.4    Dauger, S.5    Gallego, J.6
  • 63
    • 23444444510 scopus 로고    scopus 로고
    • Determinants of inspiratory activity
    • Ramirez, J.M., Viemari, J.C., Determinants of inspiratory activity. Respir Physiol Neurobiol 147:2–3 (2005), 145–157.
    • (2005) Respir Physiol Neurobiol , vol.147 , Issue.2-3 , pp. 145-157
    • Ramirez, J.M.1    Viemari, J.C.2
  • 64
    • 79960937702 scopus 로고    scopus 로고
    • Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition
    • Ray, R.S., Corcoran, A.E., Brust, R.D., Kim, J.C., Richerson, G.B., Nattie, E., Dymecki, S.M., Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition. Science 333:6042 (2011), 637–642.
    • (2011) Science , vol.333 , Issue.6042 , pp. 637-642
    • Ray, R.S.1    Corcoran, A.E.2    Brust, R.D.3    Kim, J.C.4    Richerson, G.B.5    Nattie, E.6    Dymecki, S.M.7
  • 65
    • 2642547405 scopus 로고    scopus 로고
    • Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis
    • Richerson, G.B., Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5:6 (2004), 449–461.
    • (2004) Nat Rev Neurosci , vol.5 , Issue.6 , pp. 449-461
    • Richerson, G.B.1
  • 66
    • 0028918588 scopus 로고
    • Effect of composition of experimental solutions on neuronal survival during rat brain slicing
    • Richerson, G.B., Messer, C., Effect of composition of experimental solutions on neuronal survival during rat brain slicing. Exp Neurol 131:1 (1995), 133–143.
    • (1995) Exp Neurol , vol.131 , Issue.1 , pp. 133-143
    • Richerson, G.B.1    Messer, C.2
  • 67
    • 0036487074 scopus 로고    scopus 로고
    • Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice
    • Robinson, D.M., Peebles, K.C., Kwok, H., Adams, B.M., Clarke, L.L., Woollard, G.A., Funk, G.D., Prenatal nicotine exposure increases apnoea and reduces nicotinic potentiation of hypoglossal inspiratory output in mice. J Physiol 538:3 (2002), 957–973.
    • (2002) J Physiol , vol.538 , Issue.3 , pp. 957-973
    • Robinson, D.M.1    Peebles, K.C.2    Kwok, H.3    Adams, B.M.4    Clarke, L.L.5    Woollard, G.A.6    Funk, G.D.7
  • 71
    • 0034601135 scopus 로고    scopus 로고
    • Sensing arterial CO(2) levels: a role for medullary P2X receptors
    • Spyer, K.M., Thomas, T., Sensing arterial CO(2) levels: a role for medullary P2X receptors. J Auton Nerv Syst 81:1–3 (2000), 228–235.
    • (2000) J Auton Nerv Syst , vol.81 , Issue.1-3 , pp. 228-235
    • Spyer, K.M.1    Thomas, T.2
  • 72
    • 0034894597 scopus 로고    scopus 로고
    • Development of in vivo ventilatory and single chemosensitive neuron responses to hypercapnia in rats
    • Stunden, C.E., Filosa, J.A., Garcia, A.J., Dean, J.B., Putnam, R.W., Development of in vivo ventilatory and single chemosensitive neuron responses to hypercapnia in rats. Resp Physiol 127:2–3 (2001), 135–155.
    • (2001) Resp Physiol , vol.127 , Issue.2-3 , pp. 135-155
    • Stunden, C.E.1    Filosa, J.A.2    Garcia, A.J.3    Dean, J.B.4    Putnam, R.W.5
  • 73
    • 0030833070 scopus 로고    scopus 로고
    • Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia
    • Teppema, L.J., Veening, J.G., Kranenburg, A., Dahan, A., Berkenbosch, A., Olievier, C., Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia. J Comp Neurol 388:2 (1997), 169–190.
    • (1997) J Comp Neurol , vol.388 , Issue.2 , pp. 169-190
    • Teppema, L.J.1    Veening, J.G.2    Kranenburg, A.3    Dahan, A.4    Berkenbosch, A.5    Olievier, C.6
  • 74
    • 84924719252 scopus 로고    scopus 로고
    • Serotonin neurons and central respiratory chemoreception: where are we now?
    • Teran, F.A., Massey, C.A., Richerson, G.B., Serotonin neurons and central respiratory chemoreception: where are we now?. Prog Brain Res 209 (2014), 207–233.
    • (2014) Prog Brain Res , vol.209 , pp. 207-233
    • Teran, F.A.1    Massey, C.A.2    Richerson, G.B.3
  • 75
    • 0029051506 scopus 로고
    • Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats
    • Veasey, S.C., Fornal, C.A., Metzler, C.W., Jacobs, B.L., Response of serotonergic caudal raphe neurons in relation to specific motor activities in freely moving cats. J Neurosci 15:7 (1995), 5346–5359.
    • (1995) J Neurosci , vol.15 , Issue.7 , pp. 5346-5359
    • Veasey, S.C.1    Fornal, C.A.2    Metzler, C.W.3    Jacobs, B.L.4
  • 77
    • 0032169807 scopus 로고    scopus 로고
    • Chemosensitivity of rat medullary raphe neurones in primary tissue culture
    • Wang, W., Pizzonia, J.H., Richerson, G.B., Chemosensitivity of rat medullary raphe neurones in primary tissue culture. J Physiol 511:Pt 2 (1998), 433–450.
    • (1998) J Physiol , vol.511 , pp. 433-450
    • Wang, W.1    Pizzonia, J.H.2    Richerson, G.B.3
  • 78
    • 0032947693 scopus 로고    scopus 로고
    • Development of chemosensitivity of rat medullary raphe neurons
    • Wang, W., Richerson, G.B., Development of chemosensitivity of rat medullary raphe neurons. Neuroscience 90:3 (1999), 1001–1011.
    • (1999) Neuroscience , vol.90 , Issue.3 , pp. 1001-1011
    • Wang, W.1    Richerson, G.B.2
  • 79
    • 0035003713 scopus 로고    scopus 로고
    • Acidosis-stimulated neurons of the medullary raphe are serotonergic
    • Wang, W., Tiwari, J.K., Bradley, S.R., Zaykin, R.V., Richerson, G.B., Acidosis-stimulated neurons of the medullary raphe are serotonergic. J Neurophysiol 85:5 (2001), 2224–2235.
    • (2001) J Neurophysiol , vol.85 , Issue.5 , pp. 2224-2235
    • Wang, W.1    Tiwari, J.K.2    Bradley, S.R.3    Zaykin, R.V.4    Richerson, G.B.5
  • 81
    • 33845423914 scopus 로고    scopus 로고
    • Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity
    • Zhao, Z.-Q., Scott, M., Chiechio, S., Wang, J.-S., Renner, K.J., Gereau, R.W., Johnson, R.L., Deneris, E.S., Chen, Z.-F., Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci 26:49 (2006), 12781–12788.
    • (2006) J Neurosci , vol.26 , Issue.49 , pp. 12781-12788
    • Zhao, Z.-Q.1    Scott, M.2    Chiechio, S.3    Wang, J.-S.4    Renner, K.J.5    Gereau, R.W.6    Johnson, R.L.7    Deneris, E.S.8    Chen, Z.-F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.