메뉴 건너뛰기




Volumn 6, Issue 12, 2016, Pages 4023-4033

Regulation of secondary metabolism by the velvet complex is temperature-responsive in aspergillus

Author keywords

Aspergillus fumigatus; Gene cluster; Gene expression; Gene regulation; Temperaturedependent

Indexed keywords

ASPERGILLUS FUMIGATUS; DNA TRANSCRIPTION; ENVIRONMENTAL FACTOR; EXPOSURE; GENE CLUSTER; GENE EXPRESSION REGULATION; HUMAN; METABOLITE; NONHUMAN; SECONDARY METABOLISM; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ASPERGILLUS; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MULTIGENE FAMILY; TEMPERATURE;

EID: 85008462134     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.116.033084     Document Type: Article
Times cited : (49)

References (74)
  • 1
    • 78649931835 scopus 로고    scopus 로고
    • What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis
    • Abad, A., J. V. Fernández-Molina, J. Bikandi, A. Ramírez, J. Margareto et al., 2010 What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis. Rev. Iberoam.Micol. 27: 155-182.
    • (2010) Rev. Iberoam.Micol , vol.27 , pp. 155-182
    • Abad, A.1    Fernández-Molina, J.V.2    Bikandi, J.3    Ramírez, A.4    Margareto, J.5
  • 2
    • 77957269196 scopus 로고    scopus 로고
    • Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis
    • Ames, B. D., X. Liu, and C. T. Walsh, 2010 Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis. Biochemistry 49: 8564-8576.
    • (2010) Biochemistry , vol.49 , pp. 8564-8576
    • Ames, B.D.1    Liu, X.2    Walsh, C.T.3
  • 3
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq-a python framework to work with high-throughput sequencing data
    • Anders, S., P. T. Pyl, and W. Huber, 2014 HTSeq-a python framework to work with high-throughput sequencing data. Bioinformatics 31:166-169.
    • (2014) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 4
    • 75549090164 scopus 로고    scopus 로고
    • The Aspergillus genome database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community
    • Arnaud, M. B., M. C. Chibucos, M. C. Costanzo, J. Crabtree, D. O. Inglis et al., 2010 The Aspergillus genome database, a curated comparative genomics resource for gene, protein and sequence information for the Aspergillus research community. Nucleic Acids Res. 38: D420-D 427.
    • (2010) Nucleic Acids Res , vol.38 , pp. D420-D427
    • Arnaud, M.B.1    Chibucos, M.C.2    Costanzo, M.C.3    Crabtree, J.4    Inglis, D.O.5
  • 5
    • 84862228827 scopus 로고    scopus 로고
    • The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources
    • Arnaud, M. B., G. C. Cerqueira, D. O. Inglis, M. S. Skrzypek, J. Binkley et al., 2012 The Aspergillus Genome Database (AspGD): recent developments in comprehensive multispecies curation, comparative genomics and community resources. Nucleic Acids Res. 40: D653-D 659.
    • (2012) Nucleic Acids Res , vol.40 , pp. D653-D659
    • Arnaud, M.B.1    Cerqueira, G.C.2    Inglis, D.O.3    Skrzypek, M.S.4    Binkley, J.5
  • 6
    • 78449250735 scopus 로고    scopus 로고
    • Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans
    • Atoui, A., C. Kastner, C. M. Larey, R. Thokala, O. Etxebeste et al., 2010 Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans. Fungal Genet. Biol. 47: 962-972.
    • (2010) Fungal Genet. Biol , vol.47 , pp. 962-972
    • Atoui, A.1    Kastner, C.2    Larey, C.M.3    Thokala, R.4    Etxebeste, O.5
  • 7
    • 84856569061 scopus 로고    scopus 로고
    • Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter
    • Barker, B. M., K. Kroll, M. Vödisch, A. Mazurie, O. Kniemeyer et al., 2012 Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. BMC Genomics 13: 62.
    • (2012) BMC Genomics , vol.13 , pp. 62
    • Barker, B.M.1    Kroll, K.2    Vödisch, M.3    Mazurie, A.4    Kniemeyer, O.5
  • 8
    • 83355169636 scopus 로고    scopus 로고
    • Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins
    • Bayram, O., and G. H. Braus, 2012 Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins. FEMS Microbiol. Rev. 36: 1-24.
    • (2012) FEMS Microbiol. Rev , vol.36 , pp. 1-24
    • Bayram, O.1    Braus, G.H.2
  • 9
    • 45849147020 scopus 로고    scopus 로고
    • VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism
    • Bayram, Ö., S. Krappmann, M. Ni, J. W. Bok, K. Helmstaedt et al., 2008 VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science 320: 1504-1506.
    • (2008) Science , vol.320 , pp. 1504-1506
    • Bayram, Ö.1    Krappmann, S.2    Ni, M.3    Bok, J.W.4    Helmstaedt, K.5
  • 10
    • 6544275960 scopus 로고    scopus 로고
    • Mycological control and surveillance of biological waste and compost
    • Beffa, T., F. Staib, J. Lott Fischer, P. F. Lyon, P. Gumowski et al., 1998 Mycological control and surveillance of biological waste and compost. Med. Mycol. 36(Suppl. 1): 137-145.
    • (1998) Med. Mycol , vol.36 , pp. 137-145
    • Beffa, T.1    Staib, F.2    Lott Fischer, J.3    Lyon, P.F.4    Gumowski, P.5
  • 12
    • 84876819014 scopus 로고    scopus 로고
    • Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites
    • Berthier, E., F. Y. Lim, Q. Deng, C.-J. Guo, D. P. Kontoyiannis et al., 2013 Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites. PLoS Pathog. 9: e 1003289.
    • (2013) PLoS Pathog , vol.9
    • Berthier, E.1    Lim, F.Y.2    Deng, Q.3    Guo, C.-J.4    Kontoyiannis, D.P.5
  • 13
    • 14544269834 scopus 로고    scopus 로고
    • The Aspergillus pH-responsive transcription factor PacC regulates virulence
    • Bignell, E., S. Negrete-Urtasun, A. M. Calcagno, K. Haynes, H. N. Arst et al., 2005 The Aspergillus pH-responsive transcription factor PacC regulates virulence. Mol. Microbiol. 55: 1072-1084.
    • (2005) Mol. Microbiol , vol.55 , pp. 1072-1084
    • Bignell, E.1    Negrete-Urtasun, S.2    Calcagno, A.M.3    Haynes, K.4    Arst, H.N.5
  • 14
    • 84855278233 scopus 로고    scopus 로고
    • SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus
    • Blatzer, M., B. M. Barker, S. D. Willger, N. Beckmann, S. J. Blosser et al., 2011 SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus. PLoS Genet. 7: e 1002374.
    • (2011) PLoS Genet , vol.7
    • Blatzer, M.1    Barker, B.M.2    Willger, S.D.3    Beckmann, N.4    Blosser, S.J.5
  • 16
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: a flexible trimmer for illumina sequence data
    • Bolger, A. M., M. Lohse, and B. Usadel, 2014 Trimmomatic: a flexible trimmer for illumina sequence data. Bioinformatics 30: 2114-2120.
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1    Lohse, M.2    Usadel, B.3
  • 17
    • 78349307951 scopus 로고    scopus 로고
    • Fungal genome mining and activation of silent gene clusters
    • edited by Esser, K. Sprigner-Verlag, Heidelberg
    • Brakhage, A., S. Bergmann, J. Schuemann, K. Scherlach, V. Schroeckh et al., 2009 Fungal genome mining and activation of silent gene clusters, pp. 297-303 in TheMycota XV, edited by Esser, K. Sprigner-Verlag, Heidelberg.
    • (2009) TheMycota XV , pp. 297-303
    • Brakhage, A.1    Bergmann, S.2    Schuemann, J.3    Scherlach, K.4    Schroeckh, V.5
  • 18
    • 84871292787 scopus 로고    scopus 로고
    • Regulation of fungal secondary metabolism
    • Brakhage, A. A., 2013 Regulation of fungal secondary metabolism. Nat. Rev. Microbiol. 11: 21-32.
    • (2013) Nat. Rev. Microbiol , vol.11 , pp. 21-32
    • Brakhage, A.A.1
  • 19
    • 44649167604 scopus 로고    scopus 로고
    • The VeA regulatory system and its role in morphological and chemical development in fungi
    • Calvo, A. M., 2008 The VeA regulatory system and its role in morphological and chemical development in fungi. Fungal Genet. Biol. 45: 1053-1061.
    • (2008) Fungal Genet. Biol , vol.45 , pp. 1053-1061
    • Calvo, A.M.1
  • 20
    • 84927513915 scopus 로고    scopus 로고
    • Association of fungal secondary metabolism and sclerotial biology
    • Calvo, A. M., and J. W. Cary, 2015 Association of fungal secondary metabolism and sclerotial biology. Front. Microbiol. 6: 62.
    • (2015) Front. Microbiol , vol.6 , pp. 62
    • Calvo, A.M.1    Cary, J.W.2
  • 21
    • 84969725435 scopus 로고    scopus 로고
    • Velvet regulation of fungal development
    • edited by Wendland, J. Springer International Publishing, Switzerland
    • Calvo, A., J. Lohmar, B. Ibarra, and T. Satterlee, 2016 Velvet regulation of fungal development, pp. 475-497 in Mycota, Vol. 1, edited by Wendland, J. Springer International Publishing, Switzerland.
    • (2016) Mycota , vol.1 , pp. 475-497
    • Calvo, A.1    Lohmar, J.2    Ibarra, B.3    Satterlee, T.4
  • 22
    • 84862808882 scopus 로고    scopus 로고
    • The veA gene of the pine needle pathogen Dothistroma septosporum regulates sporulation and secondary metabolism
    • Chettri, P., A. M. Calvo, J. W. Cary, S. Dhingra, Y. Guo et al., 2012 The veA gene of the pine needle pathogen Dothistroma septosporum regulates sporulation and secondary metabolism. Fungal Genet. Biol. 49: 141-151.
    • (2012) Fungal Genet. Biol , vol.49 , pp. 141-151
    • Chettri, P.1    Calvo, A.M.2    Cary, J.W.3    Dhingra, S.4    Guo, Y.5
  • 23
    • 45149124021 scopus 로고    scopus 로고
    • Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway
    • Chiang, Y.-M., E. Szewczyk, T. Nayak, A. D. Davidson, J. F. Sanchez et al., 2008 Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway. Chem. Biol. 15: 527-532.
    • (2008) Chem. Biol , vol.15 , pp. 527-532
    • Chiang, Y.-M.1    Szewczyk, E.2    Nayak, T.3    Davidson, A.D.4    Sanchez, J.F.5
  • 24
    • 33846517012 scopus 로고    scopus 로고
    • Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils
    • Coméra, C., K. André, J. Laffitte, X. Collet, P. Galtier et al., 2007 Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways in human neutrophils. Microbes Infect. 9: 47-54.
    • (2007) Microbes Infect , vol.9 , pp. 47-54
    • Coméra, C.1    André, K.2    Laffitte, J.3    Collet, X.4    Galtier, P.5
  • 25
    • 84870417381 scopus 로고    scopus 로고
    • VeA regulates conidiation, gliotoxin production and protease activity in the opportunistic human pathogen Aspergillus fumigatus
    • Dhingra, S., D. Andes, and A. M. Calvo, 2012 VeA regulates conidiation, gliotoxin production and protease activity in the opportunistic human pathogen Aspergillus fumigatus. Eukaryot. Cell 11: 1531-1543.
    • (2012) Eukaryot. Cell , vol.11 , pp. 1531-1543
    • Dhingra, S.1    Andes, D.2    Calvo, A.M.3
  • 26
    • 84885051447 scopus 로고    scopus 로고
    • The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus
    • Dhingra, S., A. L. Lind, H.-C. Lin, Y. Tang, A. Rokas et al., 2013 The fumagillin gene cluster, an example of hundreds of genes under veA control in Aspergillus fumigatus. PLoS One 8: e 77147.
    • (2013) PLoS One , vol.8
    • Dhingra, S.1    Lind, A.L.2    Lin, H.-C.3    Tang, Y.4    Rokas, A.5
  • 27
    • 0010330205 scopus 로고    scopus 로고
    • Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans
    • Feng, G. H., and T. J. Leonard, 1998 Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans. Appl. Environ. Microbiol. 64: 2275-2277.
    • (1998) Appl. Environ. Microbiol , vol.64 , pp. 2275-2277
    • Feng, G.H.1    Leonard, T.J.2
  • 29
    • 21744453939 scopus 로고    scopus 로고
    • Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus
    • Gardiner, D. M., and B. J. Howlett, 2005 Bioinformatic and expression analysis of the putative gliotoxin biosynthetic gene cluster of Aspergillus fumigatus. FEMS Microbiol. Lett. 248: 241-248.
    • (2005) FEMS Microbiol. Lett , vol.248 , pp. 241-248
    • Gardiner, D.M.1    Howlett, B.J.2
  • 30
    • 84938911283 scopus 로고    scopus 로고
    • Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals
    • Gressler, M., F. Meyer, D. Heine, P. Hortschansky, C. Hertweck et al., 2015 Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals. eLife 4: e 07861.
    • (2015) ELife , vol.4
    • Gressler, M.1    Meyer, F.2    Heine, D.3    Hortschansky, P.4    Hertweck, C.5
  • 31
    • 77955346444 scopus 로고    scopus 로고
    • Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum
    • Hoff, B., J. Kamerewerd, C. Sigl, R. Mitterbauer, I. Zadra et al., 2010 Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum. Eukaryot. Cell 9: 1236-1250.
    • (2010) Eukaryot. Cell , vol.9 , pp. 1236-1250
    • Hoff, B.1    Kamerewerd, J.2    Sigl, C.3    Mitterbauer, R.4    Zadra, I.5
  • 32
    • 84876692068 scopus 로고    scopus 로고
    • Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae
    • Inglis, D. O., J. Binkley, M. S. Skrzypek, M. B. Arnaud, G. C. Cerqueira et al., 2013 Comprehensive annotation of secondary metabolite biosynthetic genes and gene clusters of Aspergillus nidulans, A. fumigatus, A. niger and A. oryzae. BMC Microbiol. 13: 91.
    • (2013) BMC Microbiol , vol.13 , pp. 91
    • Inglis, D.O.1    Binkley, J.2    Skrzypek, M.S.3    Arnaud, M.B.4    Cerqueira, G.C.5
  • 33
    • 84939638571 scopus 로고    scopus 로고
    • Translating biosynthetic gene clusters into fungal armor and weaponry
    • Keller, N. P., 2015 Translating biosynthetic gene clusters into fungal armor and weaponry. Nat. Chem. Biol. 11: 671-677.
    • (2015) Nat. Chem. Biol , vol.11 , pp. 671-677
    • Keller, N.P.1
  • 34
    • 30544434099 scopus 로고    scopus 로고
    • Fungal secondary metabolism-from biochemistry to genomics
    • Keller, N. P., G. Turner, and J. W. Bennett, 2005 Fungal secondary metabolism-from biochemistry to genomics. Nat. Rev. Microbiol. 3: 937-947.
    • (2005) Nat. Rev. Microbiol , vol.3 , pp. 937-947
    • Keller, N.P.1    Turner, G.2    Bennett, J.W.3
  • 35
    • 0033591447 scopus 로고    scopus 로고
    • Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
    • Kennedy, J., K. Auclair, S. G. Kendrew, C. Park, J. C. Vederas et al., 1999 Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis. Science 284: 1368-1372.
    • (1999) Science , vol.284 , pp. 1368-1372
    • Kennedy, J.1    Auclair, K.2    Kendrew, S.G.3    Park, C.4    Vederas, J.C.5
  • 36
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim, D., G. Pertea, C. Trapnell, H. Pimentel, R. Kelley et al., 2013 TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14: R 36.
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5
  • 37
    • 84878012899 scopus 로고    scopus 로고
    • Bacterium induces cryptic meroterpenoid pathway in the pathogenic fungus Aspergillus fumigatus
    • König, C. C., K. Scherlach, V. Schroeckh, F. Horn, S. Nietzsche et al., 2013 Bacterium induces cryptic meroterpenoid pathway in the pathogenic fungus Aspergillus fumigatus. Chembiochem 14: 938-942.
    • (2013) Chembiochem , vol.14 , pp. 938-942
    • König, C.C.1    Scherlach, K.2    Schroeckh, V.3    Horn, F.4    Nietzsche, S.5
  • 38
    • 0032916340 scopus 로고    scopus 로고
    • Aspergillus fumigatus and Aspergillosis
    • Latge, J.-P., 1999 Aspergillus fumigatus and Aspergillosis. Clin. Microbiol. Rev. 12: 310-350.
    • (1999) Clin. Microbiol. Rev , vol.12 , pp. 310-350
    • Latge, J.-P.1
  • 39
    • 84866157264 scopus 로고    scopus 로고
    • Genome-based cluster deletion reveals an endocrocin biosynthetic pathway in Aspergillus fumigatus
    • Lim, F. Y., Y. Hou, Y. Chen, J.-H. Oh, I. Lee et al., 2012 Genome-based cluster deletion reveals an endocrocin biosynthetic pathway in Aspergillus fumigatus. Appl. Environ. Microbiol. 78: 4117-4125.
    • (2012) Appl. Environ. Microbiol , vol.78 , pp. 4117-4125
    • Lim, F.Y.1    Hou, Y.2    Chen, Y.3    Oh, J.-H.4    Lee, I.5
  • 40
    • 84875749007 scopus 로고    scopus 로고
    • The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of b-trans-bergamotene
    • Lin, H.-C., Y.-H. Chooi, S. Dhingra, W. Xu, A. M. Calvo et al., 2013 The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of b-trans-bergamotene. J. Am. Chem. Soc. 135: 4616-4619.
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 4616-4619
    • Lin, H.-C.1    Chooi, Y.-H.2    Dhingra, S.3    Xu, W.4    Calvo, A.M.5
  • 41
    • 84926357089 scopus 로고    scopus 로고
    • Examining the evolution of the regulatory circuit controlling secondary metabolism and development in the fungal genus Aspergillus
    • Lind, A. L., J. H. Wisecaver, T. D. Smith, X. Feng, A. M. Calvo et al., 2015 Examining the evolution of the regulatory circuit controlling secondary metabolism and development in the fungal genus Aspergillus. PLoS Genet. 11: e 1005096.
    • (2015) PLoS Genet , vol.11
    • Lind, A.L.1    Wisecaver, J.H.2    Smith, T.D.3    Feng, X.4    Calvo, A.M.5
  • 42
    • 84890805887 scopus 로고    scopus 로고
    • Combinatorial function of velvet and AreA in transcriptional regulation of nitrate utilization and secondary metabolism
    • López-Berges, M. S., K. Schäfer, C. Hera, and A. Di Pietro, 2014 Combinatorial function of velvet and AreA in transcriptional regulation of nitrate utilization and secondary metabolism. Fungal Genet. Biol. 62: 78-84.
    • (2014) Fungal Genet. Biol , vol.62 , pp. 78-84
    • López-Berges, M.S.1    Schäfer, K.2    Hera, C.3    Di Pietro, A.4
  • 43
    • 67651120253 scopus 로고    scopus 로고
    • Effect of competition on the production and activity of secondary metabolites in Aspergillus species
    • Losada, L., O. Ajayi, J. C. Frisvad, J. Yu, and W. C. Nierman, 2009 Effect of competition on the production and activity of secondary metabolites in Aspergillus species. Med. Mycol. 47(Suppl. 1): S88-S 96.
    • (2009) Med. Mycol , vol.47 , pp. S88-S96
    • Losada, L.1    Ajayi, O.2    Frisvad, J.C.3    Yu, J.4    Nierman, W.C.5
  • 44
    • 84924629414 scopus 로고    scopus 로고
    • Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
    • Love, M. I., W. Huber, and S. Anders, 2014 Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 15: 550.
    • (2014) Genome Biol , vol.15 , pp. 550
    • Love, M.I.1    Huber, W.2    Anders, S.3
  • 45
    • 84925405662 scopus 로고    scopus 로고
    • Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus
    • Macheleidt, J., K. Scherlach, T. Neuwirth, W. Schmidt-Heck, M. Straßburger et al., 2015 Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus. Mol. Microbiol. 96: 148-162.
    • (2015) Mol. Microbiol , vol.96 , pp. 148-162
    • Macheleidt, J.1    Scherlach, K.2    Neuwirth, T.3    Schmidt-Heck, W.4    Straßburger, M.5
  • 46
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks
    • Maere, S., K. Heymans, and M. Kuiper, 2005 BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 21: 3448-3449.
    • (2005) Bioinformatics , vol.21 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 47
    • 33745905309 scopus 로고    scopus 로고
    • The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase
    • Maiya, S., A. Grundmann, S.-M. Li, and G. Turner, 2006 The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase. ChemBioChem 7: 1062-1069.
    • (2006) ChemBioChem , vol.7 , pp. 1062-1069
    • Maiya, S.1    Grundmann, A.2    Li, S.-M.3    Turner, G.4
  • 48
    • 84947023643 scopus 로고    scopus 로고
    • Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus
    • Mattern, D. J., H. Schoeler, J. Weber, S. Novohradská, K. Kraibooj et al., 2015 Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus. Appl. Microbiol. Biotechnol. 99: 10151-10161.
    • (2015) Appl. Microbiol. Biotechnol , vol.99 , pp. 10151-10161
    • Mattern, D.J.1    Schoeler, H.2    Weber, J.3    Novohradská, S.4    Kraibooj, K.5
  • 49
    • 34547152123 scopus 로고    scopus 로고
    • The effect of elevated temperature on gene transcription and aflatoxin biosynthesis
    • O'Brian, G. R., D. R. Georgianna, J. R. Wilkinson, J. Yu, H. K. Abbas et al., 2007 The effect of elevated temperature on gene transcription and aflatoxin biosynthesis. Mycologia 99: 232-239.
    • (2007) Mycologia , vol.99 , pp. 232-239
    • O'Brian, G.R.1    Georgianna, D.R.2    Wilkinson, J.R.3    Yu, J.4    Abbas, H.K.5
  • 50
    • 85008457235 scopus 로고    scopus 로고
    • Biological activities of fungal metabolites
    • edited by An, Z. Marcel Dekker, New York
    • Paláez, F., 2004 Biological activities of fungal metabolites, pp. 49-92 in Handbook of Industrial Mycology, edited by An, Z. Marcel Dekker, New York.
    • (2004) Handbook of Industrial Mycology , pp. 49-92
    • Paláez, F.1
  • 51
    • 84873498382 scopus 로고    scopus 로고
    • Secondary metabolism and development is mediated by LlmF control of VeA subcellular localization in Aspergillus nidulans
    • Palmer, J. M., J. M. Theisen, R. M. Duran, W. S. Grayburn, A. M. Calvo et al., 2013 Secondary metabolism and development is mediated by LlmF control of VeA subcellular localization in Aspergillus nidulans. PLoS Genet. 9: e 1003193.
    • (2013) PLoS Genet , vol.9
    • Palmer, J.M.1    Theisen, J.M.2    Duran, R.M.3    Grayburn, W.S.4    Calvo, A.M.5
  • 52
    • 34247626534 scopus 로고    scopus 로고
    • Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA
    • Perrin, R. M., N. D. Fedorova, J. W. Bok, R. A. Cramer, J. R. Wortman et al., 2007 Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. PLoS Pathog. 3: e 50.
    • (2007) PLoS Pathog , vol.3
    • Perrin, R.M.1    Fedorova, N.D.2    Bok, J.W.3    Cramer, R.A.4    Wortman, J.R.5
  • 53
    • 0029328518 scopus 로고
    • Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene
    • Proctor, R. H., T. M. Hohn, and S. P. McCormick, 1995 Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene. Mol. Plant Microbe Interact. 8: 593-601.
    • (1995) Mol. Plant Microbe Interact , vol.8 , pp. 593-601
    • Proctor, R.H.1    Hohn, T.M.2    McCormick, S.P.3
  • 54
    • 39249085811 scopus 로고    scopus 로고
    • Functional and physical interaction of blue-and red-light sensors in Aspergillus nidulans
    • Purschwitz, J., S. Müller, C. Kastner, M. Schöser, H. Haas et al., 2008 Functional and physical interaction of blue-and red-light sensors in Aspergillus nidulans. Curr. Biol. 18: 255-259.
    • (2008) Curr. Biol , vol.18 , pp. 255-259
    • Purschwitz, J.1    Müller, S.2    Kastner, C.3    Schöser, M.4    Haas, H.5
  • 55
    • 57649210719 scopus 로고    scopus 로고
    • Mapping the interaction sites of Aspergillus nidulans phytochrome FphA with the global regulator VeA and the White Collar protein LreB
    • Purschwitz, J., S. Müller, and R. Fischer, 2009 Mapping the interaction sites of Aspergillus nidulans phytochrome FphA with the global regulator VeA and the White Collar protein LreB. Mol. Genet. Genomics 281: 35-42.
    • (2009) Mol. Genet. Genomics , vol.281 , pp. 35-42
    • Purschwitz, J.1    Müller, S.2    Fischer, R.3
  • 56
    • 84951127504 scopus 로고    scopus 로고
    • A phosphorylation code of the Aspergillus nidulans global regulator VelvetA (VeA) determines specific functions
    • Rauscher, S., S. Pacher, M. Hedtke, O. Kniemeyer, and R. Fischer, 2015 A phosphorylation code of the Aspergillus nidulans global regulator VelvetA (VeA) determines specific functions. Mol. Microbiol. 99: 909-924.
    • (2015) Mol. Microbiol , vol.99 , pp. 909-924
    • Rauscher, S.1    Pacher, S.2    Hedtke, M.3    Kniemeyer, O.4    Fischer, R.5
  • 57
    • 84866235346 scopus 로고    scopus 로고
    • Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus
    • Robinson, S. L., and D. G. Panaccione, 2012 Chemotypic and genotypic diversity in the ergot alkaloid pathway of Aspergillus fumigatus. Mycologia 104: 804-812.
    • (2012) Mycologia , vol.104 , pp. 804-812
    • Robinson, S.L.1    Panaccione, D.G.2
  • 58
    • 84858667719 scopus 로고    scopus 로고
    • Signaling the induction of sporulation involves the interaction of two secondary metabolites in Aspergillus nidulans
    • Rodríguez-Urra, A. B., C. Jiménez, M. I. Nieto, J. Rodríguez, H. Hayashi et al., 2012 Signaling the induction of sporulation involves the interaction of two secondary metabolites in Aspergillus nidulans. ACS Chem. Biol. 7: 599-606.
    • (2012) ACS Chem. Biol , vol.7 , pp. 599-606
    • Rodríguez-Urra, A.B.1    Jiménez, C.2    Nieto, M.I.3    Rodríguez, J.4    Hayashi, H.5
  • 59
    • 35548929808 scopus 로고    scopus 로고
    • Secondary chemicals protect mould from fungivory
    • Rohlfs, M., M. Albert, N. P. Keller, and F. Kempken, 2007 Secondary chemicals protect mould from fungivory. Biol. Lett. 3: 523-525.
    • (2007) Biol. Lett , vol.3 , pp. 523-525
    • Rohlfs, M.1    Albert, M.2    Keller, N.P.3    Kempken, F.4
  • 60
    • 0037219162 scopus 로고    scopus 로고
    • Microbiological aspects of biowaste during composting in a monitored compost bin
    • Ryckeboer, J., J. Mergaert, J. Coosemans, K. Deprins, and J. Swings, 2003 Microbiological aspects of biowaste during composting in a monitored compost bin. J. Appl. Microbiol. 94: 127-137.
    • (2003) J. Appl. Microbiol , vol.94 , pp. 127-137
    • Ryckeboer, J.1    Mergaert, J.2    Coosemans, J.3    Deprins, K.4    Swings, J.5
  • 61
    • 84901399695 scopus 로고    scopus 로고
    • Membrane-bound methyltransferase complex VapA-VipC-VapB guides epigenetic control of fungal development
    • Sarikaya-Bayram, O., O. Bayram, K. Feussner, J.-H. Kim, H.-S. Kim et al., 2014 Membrane-bound methyltransferase complex VapA-VipC-VapB guides epigenetic control of fungal development. Dev. Cell 29: 406-420.
    • (2014) Dev. Cell , vol.29 , pp. 406-420
    • Sarikaya-Bayram, O.1    Bayram, O.2    Feussner, K.3    Kim, J.-H.4    Kim, H.-S.5
  • 64
    • 0242490780 scopus 로고    scopus 로고
    • Cytoscape: a software environment for integrated models of biomolecular interaction networks
    • Shannon, P., A. Markiel, O. Ozier, N. S. Baliga, J. T. Wang et al., 2003 Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 13: 2498-2504.
    • (2003) Genome Res , vol.13 , pp. 2498-2504
    • Shannon, P.1    Markiel, A.2    Ozier, O.3    Baliga, N.S.4    Wang, J.T.5
  • 65
    • 15244354736 scopus 로고    scopus 로고
    • Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes
    • Stanzani, M., E. Orciuolo, R. Lewis, D. P. Kontoyiannis, S. L. R. Martins et al., 2005 Aspergillus fumigatus suppresses the human cellular immune response via gliotoxin-mediated apoptosis of monocytes. Blood 105: 2258-2265.
    • (2005) Blood , vol.105 , pp. 2258-2265
    • Stanzani, M.1    Orciuolo, E.2    Lewis, R.3    Kontoyiannis, D.P.4    Martins, S.L.R.5
  • 66
    • 84946735654 scopus 로고    scopus 로고
    • Gene ontology consortium: going forward
    • The Gene Ontology Consortium, 2014 Gene ontology consortium: going forward. Nucleic Acids Res. 43: D1049-D 1056.
    • (2014) Nucleic Acids Res , vol.43 , pp. D1049-D1056
  • 67
    • 84956586423 scopus 로고    scopus 로고
    • Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus
    • Throckmorton, K., F. Y. Lim, D. P. Kontoyiannis, W. Zheng, and N. P. Keller, 2015 Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus. Environ. Microbiol. 18: 246-259.
    • (2015) Environ. Microbiol , vol.18 , pp. 246-259
    • Throckmorton, K.1    Lim, F.Y.2    Kontoyiannis, D.P.3    Zheng, W.4    Keller, N.P.5
  • 68
    • 0028913388 scopus 로고
    • The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid-and alkaline-expressed genes by ambient pH
    • Tilburn, J., S. Sarkar, D. A. Widdick, E. A. Espeso, M. Orejas et al., 1995 The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid-and alkaline-expressed genes by ambient pH. EMBO J. 14: 779-790.
    • (1995) EMBO J , vol.14 , pp. 779-790
    • Tilburn, J.1    Sarkar, S.2    Widdick, D.A.3    Espeso, E.A.4    Orejas, M.5
  • 69
    • 0032693329 scopus 로고    scopus 로고
    • A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus
    • Tsai, H. F., M. H. Wheeler, Y. C. Chang, and K. J. Kwon-Chung, 1999 A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus. J. Bacteriol. 181: 6469-6477.
    • (1999) J. Bacteriol , vol.181 , pp. 6469-6477
    • Tsai, H.F.1    Wheeler, M.H.2    Chang, Y.C.3    Kwon-Chung, K.J.4
  • 70
    • 77955379554 scopus 로고    scopus 로고
    • FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence
    • Wiemann, P., D. W. Brown, K. Kleigrewe, J. W. Bok, N. P. Keller et al., 2010 FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence. Mol. Microbiol. 77: 972-994
    • (2010) Mol. Microbiol , vol.77 , pp. 972-994
    • Wiemann, P.1    Brown, D.W.2    Kleigrewe, K.3    Bok, J.W.4    Keller, N.P.5
  • 73
    • 84873683327 scopus 로고    scopus 로고
    • A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus
    • Yin, W.-B., J. A. Baccile, J. W. Bok, Y. Chen, N. P. Keller et al., 2013 A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. J. Am. Chem. Soc. 135: 2064-2067.
    • (2013) J. Am. Chem. Soc , vol.135 , pp. 2064-2067
    • Yin, W.-B.1    Baccile, J.A.2    Bok, J.W.3    Chen, Y.4    Keller, N.P.5
  • 74
    • 80051663373 scopus 로고    scopus 로고
    • Tight control of mycotoxin biosynthesis gene expression in Aspergillus flavus by temperature as revealed by RNA-Seq
    • Yu, J., N. D. Fedorova, B. G. Montalbano, D. Bhatnagar, T. E. Cleveland et al., 2011 Tight control of mycotoxin biosynthesis gene expression in Aspergillus flavus by temperature as revealed by RNA-Seq. FEMS Microbiol. Lett. 322: 145-149.
    • (2011) FEMS Microbiol. Lett , vol.322 , pp. 145-149
    • Yu, J.1    Fedorova, N.D.2    Montalbano, B.G.3    Bhatnagar, D.4    Cleveland, T.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.