The effect of elevated temperature on gene transcription and aflatoxin biosynthesis

Mycologia

Volumn 99, Issue 2, 2007, Pages 232-239

  Obrian, G R ^a   Georgianna, D R ^a   Wilkinson, J R ^b   Yu, J ^c   Abbas, H K ^d   Bhatnagar, D ^c   Cleveland, T E ^c   Nierman, W ^e   Payne, G A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b MISSISSIPPI STATE UNIVERSITY   (United States)

^c SOUTHERN REGIONAL RESEARCH CENTER   (United States)

^d AGRICULTURAL RESEARCH SERVICE   (United States)

^e J CRAIG VENTER INSTITUTE   (United States)

Author keywords

AFLR; Biosynthesis; Micro arrays

Indexed keywords

AFLATOXIN; AFLR PROTEIN, ASPERGILLUS; DNA BINDING PROTEIN; FUNGAL PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

CATALYSIS; ENVIRONMENTAL CONDITIONS; GENE EXPRESSION; TEMPERATURE EFFECT; TOXIN;

ARTICLE; ASPERGILLUS FLAVUS; BIOSYNTHESIS; COMPARATIVE STUDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEAT; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

AFLATOXINS; ASPERGILLUS FLAVUS; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; HEAT; POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

ASPERGILLUS FLAVUS; FUNGI;

EID: 34547152123     PISSN: 00275514     EISSN: 15572536     Source Type: Journal    
DOI: 10.3852/mycologia.99.2.232     Document Type: Article

References (38)

1. Abbas HK, Zablotowicz RM, Weaver BW, Horn BW, Xie W. 2004. Comparison of cultural and analytical methods for determination of aflatoxin production by Mississippi Delta Aspergillus isolates. Can J Microbiol 50(3):193-199.
2. Bennett JW, Klich M. 2003. Mycotoxins. Clin Microbiol Rev 16(3):497-516.
3. Bhatnagar D, Ehrlich KC, Cleveland TE. 2003. Molecular genetic analysis and regulation of aflatoxin biosynthesis. Appl Microbiol Biotechnol 61(2):83-93.
4. Bok JW, Keller NP. 2004. LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot Cell 3(2):527-535.
5. Bressac B, Kew M, Wands J, Ozturk M. 1991. Selective Gmutation to T-mutation of P53 Gene in hepatocellular-carcinoma from southern Africa. Nature 350(6317):429-431.
6. Cary JW, Klich MA, Beltz SB. 2005. Characterization of aflatoxin producing fungi outside of Aspergillus section Flavi. Mycologia 97(2):425-432.
7. Chang PK. 2003. The Aspergillus parasiticus protein aflJ interacts with the aflatoxin pathway-specific regulator AFLR. Mol Genet Genomics 268(6):711-719.
8. Diener UL, Davis ND. 1967. Limiting temperature and relative humidity for growth and production of aflatoxin and free fatty acids by Aspergillus flavus in sterile peanuts. J Am Oil Chem Soc 44(4):259.
9. Feng GH, Leonard TJ. 1995. Characterization of the polyketide synthase gene (PksII) required for aflatoxin biosynthesis in Aspergillus parasiticus. J Bacteriol 177(21):6246-6254.
10. _. 1998. Culture conditions control expression of the genes for aflatoxin and sterigmatocystin biosynthesis in Aspergillus parasiticus and A. nidulans. Appl Environ Microbiol 64(6):2275-2277.
11. Hsu IC, Metcalf RA, Sun T, Welsh JA, Wang NJ, Harris CC. 1991. Mutational hotspot in the P53 gene in human hepatocellular carcinomas. Nature 350(6317):427-428.
12. Jain AN, Tokuyasu TA, Snijders AM, Segraves R, Albertson DG, Pinkel D. 2002. Fully automatic quantification of microarray image data. Genome Res 12(2):325-332.
13. Kraus PR, Boily MJ, Giles SS, Stajich JE, Allen A, Cox GM, Dietrich FS, Perfect JR, Heitman J. 2004. Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray. Eukaryot Cell 3(5):1249-1260.
14. Lewis L, Onsongo M, Njapau H, Schurz-Rogers H, Luber G, Kieszak S, Nyamongo J, Backer L, Dahiye AM, Misore A, De Cock K, Rubin C. 2005. Aflatoxin contamination of commercial maize products during an outbreak of acute aflatoxicosis in eastern and central Kenya. Environ Health Perspect 113(12):1763-1767.
15. Liu BH, Chu FS. 1998. Regulation of aflR and its product, AflR, associated with aflatoxin biosynthesis. Appl Environ Microbiol 64(10):3718-3723.
16. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) method. Methods 25(4):402-408.
17. Luchese RH, Harrigan WF. 1993. Biosynthesis of aflatoxin - the role of nutritional factors. J Appl Bacteriol 74(1):5-14.
18. Mayne RY, Franz AO, Goldblat LA. 1967. Effect of temperature and substrate on production of aflatoxin. J Am Oil Chem Soc 44(3):A107.
19. Meyers DM, Obrian G, Du WL, Bhatnagar D, Payne GA. 1998. Characterization of aflJ, a gene required for conversion of pathway intermediates to aflatoxin. Appl Environ Microbiol 64(10):3713-3717.
20. OBrian GR, Fakhoury AM, Payne GA. 2003. Identification of genes differentially expressed during aflatoxin biosynthesis in Aspergillus flavus and Aspergillus parasiticus. Fungal Genet Biol 39(2):118-127.
21. Payne GA, Brown MP. 1998. Genetics and physiology of aflatoxin biosynthesis. Ann Rev Phytopathol 36:329-362.
22. Price MS, Conners SB, Tachdjian S, Kelly RM, Payne GA. 2005. Aflatoxin conducive and non-conducive growth conditions reveal new gene associations with aflatoxin production. Fungal Genet Biol 42(6):506-518.
23. _, Yu J, Nierman WC, Kim HS, Pritchard B, Jacobus CA, Bhatnagar D, Cleveland TE, Payne GA. 2006. The aflatoxin pathway regulator AflR induces gene transcription inside and outside of the aflatoxin biosynthetic cluster. FEMS Microbiol Lett 255(2):275-279.
24. Richard JL, Payne GA. 2003. Mycotoxins: risks in plant, animal and human systems. Ames, Iowa: Council for Agricultural Science and Technology.
25. Samson RA. 2001. Current fungal taxonomy and mycotoxins. Mycotoxins and Phycotoxins in Perspective at the Turn of the Millennium. Wageningen, The Netherlands: Ponsen & Looyen.
26. Schindler AF, Palmer JG, Eisenber WV. 1967. Aflatoxin production by Aspergillus flavus as related to various temperatures. Appl Microbiol 15(5):1006-1009.
27. Schroeder HW, Hein H Jr. 1967. Aflatoxins: production of the toxins in vitro in relation to temperature. Appl Microbiol 15(2):441-445.
28. _. 1968. Effect of diurnal temperature cycles on the production of aflatoxin. Appl Microbiol 16(7):988-990.
29. Shimizu K, Hicks JK, Huang TP, Keller NP. 2003. Pka, Ras and RGS protein interactions regulate activity of AflR, a Zn(II)2Cys6 transcription factor in Aspergillus nidulans. Genetics 165(3):1095-1104.
30. Sobolev VS, Dorner JW. 2002. Cleanup procedure for determination of aflatoxin in major agricultural commodities by liquid chromatography. J AOAC Internat 85(3):642-645.
31. Varga J, Rigo K, Toth B, Teren J, Kozakiewicz Z. 2003. Evolutionary relationships among Aspergillus species producing economically important mycotoxins. Food Tech Biotech 41(1):29-36.
32. Wang JS, Huang T, Su J, Liang F, Wei Z, Liang Y, Luo H, Kuang SY, Qian GS, Sun G, He X, Kensler TW, Groopman JD. 2001. Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiol Biomarkers Prev 10(2):143-146.
33. Wilkinson HH, Ramaswamy A, Sim SC, Keller NP. 2004. Increased conidiation associated with progression along the sterigmatocystin biosynthetic pathway. Mycologia 96(6):1190-1198.
34. Wolfinger RD, Gibson G, Wolfinger ED, Bennett L, Hamadeh H, Bushel P, Afshari C, Paules RS. 2001. Assessing gene significance from cDNA microarray expression data via mixed models. J Comput Biol 8(6):625-637.
35. Woloshuk CP, Foutz KR, Brewer JF, Bhatnagar D, Cleveland TE, Payne GA. 1994. Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis. Appl Environ Microbiol 60(7):2408-2414.
36. Yu J, Whitelaw CA, Nierman WC, Bhatnagar D, Cleveland TE. 2004c. Aspergillus flavus expressed sequence tags for identification of genes with putative roles in aflatoxin contamination of crops. FEMS Microbiol Lett 237(2):333-340.
37. _, Bhatnagar D, Cleveland TE. 2004a. Completed sequence of aflatoxin pathway gene cluster in Aspergillus parasiticus. FEBS Lett 564(1-2):126-130.
38. _, Chang PK, Ehrlich KC, Cary JW, Bhatnagar D, Cleveland TE, Payne GA, Linz JE, Woloshuk CP, Bennett JW. 2004b. Clustered pathway genes in aflatoxin biosynthesis. Appl Environ Microbiol 70(3): 1253-1262.