The placental interleukin-6 signaling controls fetal brain development and behavior

Brain, Behavior, and Immunity

Volumn 62, Issue , 2017, Pages 11-23

  Wu, Wei Li ^a   Hsiao, Elaine Y ^a,b   Yan, Zihao ^a   Mazmanian, Sarkis K ^a   Patterson, Paul H ^a  

^a California Institute of Technology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autism spectrum disorder (ASD); Hindbrain development; Interleukin 6 (IL 6); Maternal immune activation (MIA); Maternal placental fetal axis; Placenta; Purkinje cells

Indexed keywords

INTERLEUKIN 6; JANUS KINASE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTOME; INTERLEUKIN 6 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; CRYOPRESERVATION; CYTOKINE PRODUCTION; DNA EXTRACTION; ENZYME ACTIVATION; FEMALE; FETUS; FETUS BRAIN; GENE AMPLIFICATION; GENE FREQUENCY; GENOTYPE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PURKINJE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA DEGRADATION; SIGNAL TRANSDUCTION; TROPHOBLAST; ANIMAL; ANIMAL BEHAVIOR; BRAIN; EMBRYOLOGY; FETUS DEVELOPMENT; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PLACENTA; PREGNANCY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; FEMALE; FETAL DEVELOPMENT; INTERLEUKIN-6; MICE; MICE, KNOCKOUT; PLACENTA; PREGNANCY; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION;

EID: 85007485854     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2016.11.007     Document Type: Article

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