-
1
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, et al. Signatures of mutational processes in human cancer. Nature. 2013;500(7463):415-21.
-
(2013)
Nature
, vol.500
, Issue.7463
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
-
2
-
-
1842862755
-
TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer
-
Olivier M, Hussain SP, de FC C, Hainaut P, Harris CC. TP53 mutation spectra and load: a tool for generating hypotheses on the etiology of cancer. IARC Sci Publ. 2004;157:247-70.
-
(2004)
IARC Sci Publ
, vol.157
, pp. 247-270
-
-
Olivier, M.1
Hussain, S.P.2
Caron de Fromentel, C.3
Hainaut, P.4
Harris, C.C.5
-
3
-
-
84873186179
-
Deciphering signatures of mutational processes operative in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, Campbell PJ, Stratton MR. Deciphering signatures of mutational processes operative in human cancer. Cell Rep. 2013;3(1):246-59.
-
(2013)
Cell Rep
, vol.3
, Issue.1
, pp. 246-259
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Campbell, P.J.4
Stratton, M.R.5
-
4
-
-
84891102589
-
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
-
Alexandrov LB, Stratton MR. Mutational signatures: the patterns of somatic mutations hidden in cancer genomes. Curr Opin Genet Dev. 2014;24:52-60.
-
(2014)
Curr Opin Genet Dev
, vol.24
, pp. 52-60
-
-
Alexandrov, L.B.1
Stratton, M.R.2
-
5
-
-
84906303775
-
Mechanisms underlying mutational signatures in human cancers
-
Helleday T, Eshtad S, Nik-Zainal S. Mechanisms underlying mutational signatures in human cancers. Nat Rev Genet. 2014;15(9):585-98.
-
(2014)
Nat Rev Genet
, vol.15
, Issue.9
, pp. 585-598
-
-
Helleday, T.1
Eshtad, S.2
Nik-Zainal, S.3
-
6
-
-
84861541343
-
Mutational processes molding the genomes of 21 breast cancers
-
Nik-Zainal S, Alexandrov LB, Wedge DC, Van LP, Greenman CD, Raine K, et al. Mutational processes molding the genomes of 21 breast cancers. Cell. 2012; 149(5):979-93.
-
(2012)
Cell
, vol.149
, Issue.5
, pp. 979-993
-
-
Nik-Zainal, S.1
Alexandrov, L.B.2
Wedge, D.C.3
Van, L.P.4
Greenman, C.D.5
Raine, K.6
-
7
-
-
84907481031
-
C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency
-
Meier B, Cooke SL, Weiss J, Bailly AP, Alexandrov LB, Marshall J, et al. C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency. Genome Res. 2014;24(10):1624-36.
-
(2014)
Genome Res
, vol.24
, Issue.10
, pp. 1624-1636
-
-
Meier, B.1
Cooke, S.L.2
Weiss, J.3
Bailly, A.P.4
Alexandrov, L.B.5
Marshall, J.6
-
8
-
-
84905382541
-
Modelling mutational landscapes of human cancers in vitro
-
Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallee MP, et al. Modelling mutational landscapes of human cancers in vitro. Sci Rep. 2014;4:4482.
-
(2014)
Sci Rep
, vol.4
, pp. 4482
-
-
Olivier, M.1
Weninger, A.2
Ardin, M.3
Huskova, H.4
Castells, X.5
Vallee, M.P.6
-
9
-
-
84883872416
-
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool
-
Poon SL, Pang ST, McPherson JR, Yu W, Huang KK, Guan P, et al. Genome-wide mutational signatures of aristolochic acid and its application as a screening tool. Sci Transl Med. 2013;5(197):197ra101.
-
(2013)
Sci Transl Med
, vol.5
, Issue.197
-
-
Poon, S.L.1
Pang, S.T.2
McPherson, J.R.3
Yu, W.4
Huang, K.K.5
Guan, P.6
-
10
-
-
84912046893
-
Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells
-
Severson PL, Vrba L, Stampfer MR, Futscher BW. Exome-wide mutation profile in benzo[a]pyrene-derived post-stasis and immortal human mammary epithelial cells. Mutat Res Genet Toxicol Environ Mutagen. 2014;775-776:48-54.
-
(2014)
Mutat Res Genet Toxicol Environ Mutagen
, vol.775-776
, pp. 48-54
-
-
Severson, P.L.1
Vrba, L.2
Stampfer, M.R.3
Futscher, B.W.4
-
11
-
-
84938292675
-
Dissecting genetic and environmental mutation signatures with model organisms
-
Segovia R, Tam AS, Stirling PC. Dissecting genetic and environmental mutation signatures with model organisms. Trends Genet. 2015;31(8):465-74.
-
(2015)
Trends Genet
, vol.31
, Issue.8
, pp. 465-474
-
-
Segovia, R.1
Tam, A.S.2
Stirling, P.C.3
-
12
-
-
84925536961
-
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
-
Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, et al. The mutational landscapes of genetic and chemical models of Kras-driven lung cancer. Nature. 2015;517(7535):489-92.
-
(2015)
Nature
, vol.517
, Issue.7535
, pp. 489-492
-
-
Westcott, P.M.1
Halliwill, K.D.2
To, M.D.3
Rashid, M.4
Rust, A.G.5
Keane, T.M.6
-
13
-
-
84938770070
-
Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma
-
Nassar D, Latil M, Boeckx B, Lambrechts D, Blanpain C. Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma. Nat Med. 2015;21(8):946-54.
-
(2015)
Nat Med
, vol.21
, Issue.8
, pp. 946-954
-
-
Nassar, D.1
Latil, M.2
Boeckx, B.3
Lambrechts, D.4
Blanpain, C.5
-
14
-
-
77955801615
-
Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
-
Goecks J, Nekrutenko A, Taylor J. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol. 2010;11(8):R86.
-
(2010)
Genome Biol
, vol.11
, Issue.8
-
-
Goecks, J.1
Nekrutenko, A.2
Taylor, J.3
-
15
-
-
25844449770
-
Galaxy: a platform for interactive large-scale genome analysis
-
Giardine B, Riemer C, Hardison RC, Burhans R, Elnitski L, Shah P, et al. Galaxy: a platform for interactive large-scale genome analysis. Genome Res. 2005;15(10):1451-5.
-
(2005)
Genome Res
, vol.15
, Issue.10
, pp. 1451-1455
-
-
Giardine, B.1
Riemer, C.2
Hardison, R.C.3
Burhans, R.4
Elnitski, L.5
Shah, P.6
-
16
-
-
75949108066
-
Galaxy: a web-based genome analysis tool for experimentalists
-
Chapter 19:Unit-21
-
Blankenberg D, Von KG, Coraor N, Ananda G, Lazarus R, Mangan M, et al. Galaxy: a web-based genome analysis tool for experimentalists. Curr Protoc Mol Biol. 2010;Chapter 19:Unit-21.
-
(2010)
Curr Protoc Mol Biol
-
-
Blankenberg, D.1
Von, K.G.2
Coraor, N.3
Ananda, G.4
Lazarus, R.5
Mangan, M.6
-
17
-
-
77956534324
-
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
-
Wang K, Li M, Hakonarson H. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 2010;38(16):e164.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.16
-
-
Wang, K.1
Li, M.2
Hakonarson, H.3
-
18
-
-
77954069195
-
A flexible R package for nonnegative matrix factorization
-
Gaujoux R, Seoighe C. A flexible R package for nonnegative matrix factorization. BMC Bioinformatics. 2010;11:367.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 367
-
-
Gaujoux, R.1
Seoighe, C.2
-
19
-
-
1642529511
-
Metagenes and molecular pattern discovery using matrix factorization
-
Brunet JP, Tamayo P, Golub TR, Mesirov JP. Metagenes and molecular pattern discovery using matrix factorization. Proc Natl Acad Sci U S A. 2004;101(12):4164-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.12
, pp. 4164-4169
-
-
Brunet, J.P.1
Tamayo, P.2
Golub, T.R.3
Mesirov, J.P.4
-
20
-
-
84947024951
-
LSAfun-An R package for computations based on Latent Semantic Analysis
-
Gunther F, Dudschig C, Kaup B. LSAfun-An R package for computations based on Latent Semantic Analysis. Behav Res Methods. 2015;47(4):930-44.
-
(2015)
Behav Res Methods
, vol.47
, Issue.4
, pp. 930-944
-
-
Gunther, F.1
Dudschig, C.2
Kaup, B.3
-
21
-
-
84946040120
-
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
-
Forbes SA, Beare D, Gunasekaran P, Leung K, Bindal N, Boutselakis H, et al. COSMIC: exploring the world's knowledge of somatic mutations in human cancer. Nucleic Acids Res. 2015;43(Database issue):D805-11.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.DATABASE ISSUE
, pp. D805-D811
-
-
Forbes, S.A.1
Beare, D.2
Gunasekaran, P.3
Leung, K.4
Bindal, N.5
Boutselakis, H.6
-
22
-
-
84890177607
-
Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups
-
Maitra A, Biswas NK, Amin K, Kowtal P, Kumar S, Das S, et al. Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups. Nat Commun. 2013;4:2873.
-
(2013)
Nat Commun
, vol.4
, pp. 2873
-
-
Maitra, A.1
Biswas, N.K.2
Amin, K.3
Kowtal, P.4
Kumar, S.5
Das, S.6
-
23
-
-
84883356320
-
Evidence for APOBEC3B mutagenesis in multiple human cancers
-
Burns MB, Temiz NA, Harris RS. Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat Genet. 2013;45(9):977-83.
-
(2013)
Nat Genet
, vol.45
, Issue.9
, pp. 977-983
-
-
Burns, M.B.1
Temiz, N.A.2
Harris, R.S.3
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