Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity

Biomedicine and Pharmacotherapy

Volumn 87, Issue , 2017, Pages 73-81

  Sampath, Chethan ^a   Rashid, Muhammed Raihan ^a   Sang, Shengmin ^b   Ahmedna, Mohamed ^a  

^a Qatar University   (Qatar)

^b NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

Advance glycation end products; Diabetes; Dicarbonyl stress; Epigallocatechin gallate; Nrf2; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; EPIGALLOCATECHIN GALLATE; GLUCOSE; INSULIN; TRANSCRIPTION FACTOR NRF2; CATECHIN; NFE2L2 PROTEIN, MOUSE; TEA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; C57BL/6N MOUSE; CONTROLLED STUDY; DIET INDUCED OBESITY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; KIDNEY MASS; LIPID DIET; LIVER WEIGHT; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; TEA; WEIGHT GAIN; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; OBESITY; PHYSIOLOGY; RANDOMIZATION; SIGNAL TRANSDUCTION;

ANIMALS; CATECHIN; DIET, HIGH-FAT; GLYCOSYLATION END PRODUCTS, ADVANCED; HYPERGLYCEMIA; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; OBESITY; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; TEA;

EID: 85007472384     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.12.082     Document Type: Article

References (44)

1. [1] world health organisati, Obesity: Preventing and Managing the Global Epidemic. 2000.
2. [2] IDF Diabetes Atlas Update Poster. 7th ed., 2015, International Diabetes Federation, Brussels, Belgium.
3. [3] Roblin, L., Childhood obesity: food, nutrient, and eating-habit trends and influences. Appl. Physiol. Nutr. Metab. 32 (2007), 635–645, 10.1139/H07-046.
4. [4] Anders, S., Diabetes, Schroeter C., diet-health behavior, and obesity. Front. Endocrinol. (Lausanne), 6, 2015, 33, 10.3389/fendo.2015.00033.
5. [5] Allaman, I., Bélanger, M., Methylglyoxal, Magistretti P.J., the dark side of glycolysis. Front. Neurosci., 9, 2015, 23, 10.3389/fnins.2015.00023.
6. [6] Lee, B.-H., Hsu, W.-H., Chang, Y.-Y., Kuo, H.-F., Hsu, Y.-W., Pan Ankaflavin, T.-M., A natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic. Biol. Med. 53 (2012), 2008–2016, 10.1016/j.freeradbiomed.2012.09.025.
7. [7] Teerlink, T., Barto, R., Ten Brink, H.J., Schalkwijk, C.G., Measurement of Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine in human plasma protein by stable-isotope-dilution tandem mass spectrometry. Clin. Chem. 50 (2004), 1222–1228, 10.1373/clinchem.2004.031286.
8. [8] Shao, X., Bai, N., He, K., Ho, C.-T., Yang, C.S., Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species. Chem. Res. Toxicol. 21 (2008), 2042–2050, 10.1021/tx800227v.
9. [9] Naito, Y., Yoshikawa, T., Green tea and heart health. J. Cardiovasc. Pharmacol. 54 (2009), 385–390, 10.1097/FJC.0b013e3181b6e7a1.
10. [10] Grove, K.A., Lambert, J.D., Laboratory, epidemiological, and human intervention studies show that tea (Camellia sinensis) may be useful in the prevention of obesity. J. Nutr. 140 (2010), 446–453, 10.3945/jn.109.115972.
11. [11] Wolfram, S., Raederstorff, D., Preller, M., Wang, Y., Teixeira, S.R., Riegger, C., et al. Epigallocatechin gallate supplementation alleviates diabetes in rodents. J. Nutr. 136 (2006), 2512–2518.
12. [12] Yang, C.S., Wang, X., Lu, G., Picinich, S.C., Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer 9 (2009), 429–439, 10.1038/nrc2641.
13. [13] Bode, A.M., Dong, Z., Epigallocatechin 3-gallate and green tea catechins: united they work, divided they fail. Cancer Prev. Res. (Phila.) 2 (2009), 514–517, 10.1158/1940-6207.CAPR-09-0083.
14. [14] Dou, Q.P., Molecular mechanisms of green tea polyphenols. Nutr. Cancer 61 (2009), 827–835, 10.1080/01635580903285049.
15. [15] Yang, C.S., Sang, S., Lambert, J.D., Hou, Z., Ju, J., Lu, G., Possible mechanisms of the cancer-preventive activities of green tea. Mol. Nutr. Food Res. 50 (2006), 170–175, 10.1002/mnfr.200500105.
16. [16] Uchiyama, Y., Suzuki, T., Mochizuki, K., Goda, T., Dietary supplementation with (−)-epigallocatechin-3-gallate reduces inflammatory response in adipose tissue of non-obese type 2 diabetic Goto-Kakizaki (GK) rats. J. Agric. Food Chem. 61 (2013), 11410–11417, 10.1021/jf401635w.
17. [17] Cai, E.P., Lin, J.-K., Epigallocatechin gallate (EGCG) and rutin suppress the glucotoxicity through activating IRS2 and AMPK signaling in rat pancreatic beta cells. J. Agric. Food Chem. 57 (2009), 9817–9827, 10.1021/jf902618v.
18. [18] Song, Y., Manson, J.E., Buring, J.E., Sesso, H.D., Liu, S., Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysis. J. Am. Coll. Nutr. 24 (2005), 376–384.
19. [19] Friedrich, M., Petzke, K.J., Raederstorff, D., Wolfram, S., Klaus, S., Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet. Int. J. Obes. (Lond.) 36 (2012), 735–743, 10.1038/ijo.2011.136.
20. [20] Grove, K.A., Sae-tan, S., Kennett, M.J., Lambert, J.D., (−)-Epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice. Obesity (Silver Spring) 20 (2012), 2311–2313, 10.1038/oby.2011.139.
21. [21] Sang, S., Shao, X., Bai, N., Lo, C.-Y., Yang, C.S., Ho, C.-T., Tea polyphenol (−)-epigallocatechin-3-gallate: a new trapping agent of reactive dicarbonyl species. Chem. Res. Toxicol. 20 (2007), 1862–1870, 10.1021/tx700190s.
22. [22] Sampath, C., Zhu, Y., Sang, S., Ahmedna, M., Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells. Phytomedicine 23 (2016), 200–213, 10.1016/j.phymed.2015.12.013.
23. [23] Bose, M., Lambert, J.D., Ju, J., Reuhl, K.R., Shapses, S.A., Yang, C.S., The major green tea polyphenol, (−)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice. J. Nutr. 138 (2008), 1677–1683.
24. [24] Zhao, Y., Sedighi, R., Wang, P., Chen, H., Zhu, Y., Sang, S., Carnosic acid as a major bioactive component in rosemary extract ameliorates high-fat-diet-induced obesity and metabolic syndrome in mice. J. Agric. Food Chem. 63 (2015), 4843–4852, 10.1021/acs.jafc.5b01246.
25. [25] Samarghandian, S., Farkhondeh, T., Samini, F., Borji, A., Protective effects of carvacrol against oxidative stress induced by chronic stress in rat's brain, liver, and kidney. Biochem. Res. Int., 2016, 2016, 2645237, 10.1155/2016/2645237.
26. [26] Tang, Y., Zhong, Z., Obtusifolin treatment improves hyperlipidemia and hyperglycemia: possible mechanism involving oxidative stress. Cell Biochem. Biophys. 70 (2014), 1751–1757, 10.1007/s12013-014-0124-0.
27. [27] Steffen, L.M. Five or more servings of fruit and vegetables each day for better health! In: Ronald RW, editor. Complement. Altern. Ther. Aging Popul., San Diego: Academic Press; 2009, p. 417–431.
28. [28] Klaus, S., Pültz, S., Thöne-Reineke, C., Wolfram, S., Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation. Int. J. Obes. (Lond.) 29 (2005), 615–623, 10.1038/sj.ijo.0802926.
29. [29] Wolfram, S., Raederstorff, D., Wang, Y., Teixeira, S.R., Elste, V., Weber, P., TEAVIGO™ (Epigallocatechin gallate) supplementation prevents obesity in rodents by reducing adipose tissue mass. Ann. Nutr. Metab. 49 (2005), 54–63, 10.1159/000084178.
30. [30] Ahmad, R.S., Butt, M.S., Sultan, M.T., Mushtaq, Z., Ahmad, S., Dewanjee, S., et al. Preventive role of green tea catechins from obesity and related disorders especially hypercholesterolemia and hyperglycemia. J. Transl. Med., 13, 2015, 79, 10.1186/s12967-015-0436-x.
31. [31] Lu, S.C., Glutathione synthesis. Biochim. Biophys. Acta 1830 (2013), 3143–3153, 10.1016/j.bbagen.2012.09.008.
32. [32] Lu, J., Holmgren, A., The thioredoxin antioxidant system. Free Radic. Biol. Med. 66 (2014), 75–87, 10.1016/j.freeradbiomed.2013.07.036.
33. [33] Wu, L.-Y., Juan, C.-C., Hwang, L.S., Hsu, Y.-P., Ho, P.-H., Ho, L.-T., Green tea supplementation ameliorates insulin resistance and increases glucose transporter IV content in a fructose-fed rat model. Eur. J. Nutr. 43 (2004), 116–124, 10.1007/s00394-004-0450-x.
34. [34] Koyama, Y., Abe, K., Sano, Y., Ishizaki, Y., Njelekela, M., Shoji, Y., et al. Effects of green tea on gene expression of hepatic gluconeogenic enzymes in vivo. Planta Med. 70 (2004), 1100–1102, 10.1055/s-2004-832659.
35. [35] Waltner-Law, M.E., Wang, X.L., Law, B.K., Hall, R.K., Nawano, M., Granner, D.K., Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J. Biol. Chem. 277 (2002), 34933–34940, 10.1074/jbc.M204672200.
36. [36] Wolfram, S., Wang, Y., Thielecke, F., Anti-obesity effects of green tea: from bedside to bench. Mol. Nutr. Food Res. 50 (2006), 176–187, 10.1002/mnfr.200500102.
37. [37] Plebanski, M., Elson, C.J., Billington, W.D., Dependency on interleukin-1 of primary human in vitro T cell responses to soluble antigens. Eur. J. Immunol. 22 (1992), 2353–2358, 10.1002/eji.1830220926.
38. [38] Lin, C.-L., Lin, J.-K., Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells. Mol. Nutr. Food Res. 52 (2008), 930–939, 10.1002/mnfr.200700437.
39. [39] Morino, K., Petersen, K.F., Shulman, G.I., Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 55:Suppl. 2 (2006), S9–S15, 10.2337/diabetes.
40. [40] Shen, G., Xu, C., Hu, R., Jain, M.R., Nair, S., Lin, W., et al. Comparison of (−)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice. Pharm. Res. 22 (2005), 1805–1820, 10.1007/s11095-005-7546-8.
41. [41] Bhakkiyalakshmi, E., Sireesh, D., Rajaguru, P., Paulmurugan, R., Ramkumar, K.M., The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes. Pharmacol. Res. 91 (2015), 104–114, 10.1016/j.phrs.2014.10.004.
42. [42] Zhang, X., Liang, D., Guo, L., Liang, W., Jiang, Y., Li, H., et al. Curcumin protects renal tubular epithelial cells from high glucose-induced epithelial-to-mesenchymal transition through Nrf2-mediated upregulation of heme oxygenase-1. Mol. Med. Rep. 12 (2015), 1347–1355, 10.3892/mmr.2015.3556.
43. [43] Babu, P., Suresh Babu, K., Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats. Mol. Cell. Biochem. 181 (1998), 87–96.
44. [44] Sang, S., Shao, X., Bai, N., Lo, C.-Y., Yang, C.S., Ho, C.-T., Tea polyphenol (−)-epigallocatechin-3-gallate: a new trapping agent of reactive dicarbonyl species. Chem. Res. Toxicol. 20 (2007), 1862–1870, 10.1021/tx700190s.