The unfolded protein response mediates fibrogenesis and collagen I secretion through regulating TANGO1 in mice

Hepatology

Volumn 65, Issue 3, 2017, Pages 983-998

  Maiers, Jessica L ^a   Kostallari, Enis ^a   Mushref, Malek ^a   deAssuncao, Thiago M ^a   Li, Haiyang ^a   Jalan Sakrikar, Nidhi ^a   Huebert, Robert C ^a   Cao, Sheng ^a   Malhi, Harmeet ^a   Shah, Vijay H ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ALPHA SMOOTH MUSCLE ACTIN; CARRIER PROTEINS AND BINDING PROTEINS; CASPASE 3; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 1; DESMIN; ENDOPLASMIC RETICULUM DEGRADATION ENHANCER MANNOSIDASE ALPHA; ERDJ4 PROTEIN; FIBRONECTIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROCOLLAGEN; PROCOLLAGEN TYPE 1; PROTEIN IRE1; REGULATOR PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; TRANSPORT AND GOLGI ORGANIZATION 1 PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; BENZYLIDENE DERIVATIVE; HYDANTOIN DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1BETA; TANGO PROTEIN, MOUSE; UPR1024;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BILE DUCT LIGATION; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CELL MEMBRANE; CELL NUCLEUS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CYTOSOL; EMBRYO; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FIBROGENESIS; HEPATIC STELLATE CELL; HUMAN; HUMAN TISSUE; IN VIVO STUDY; LIVER CIRRHOSIS; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ANIMAL; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROCEDURES; RANDOMIZATION; SECRETION (PROCESS); SENSITIVITY AND SPECIFICITY;

ANIMALS; APOPTOSIS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BENZYLIDENE COMPOUNDS; CELLS, CULTURED; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; HUMANS; HYDANTOINS; IMMUNOBLOTTING; LIVER CIRRHOSIS; MICE; MICROSCOPY, CONFOCAL; POLYMERASE CHAIN REACTION; RANDOM ALLOCATION; SENSITIVITY AND SPECIFICITY; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

EID: 85007452945     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28921     Document Type: Article

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