Early hypermethylation of hepatic Igfbp2 results in its reduced expression preceding fatty liver in mice

Human Molecular Genetics

Volumn 25, Issue 12, 2016, Pages 2588-2599

  Kammel, Anne ^a,b   Saussenthaler, Sophie ^a,b   Jähnert, Markus ^a,b   Jonas, Wenke ^a,b   Stirm, Laura ^b,c   Hoeflich, Andreas ^d   Staiger, Harald ^b,c   Fritsche, Andreas ^b,c   Häring, Hans Ulrich ^b,c   Joost, Hans Georg ^a,b   Schürmann, Annette ^a,b   Schwenk, Robert W ^a,b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^c University Hospital Tü bingen   (Germany)

^d LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOSE; INSULIN; LEPTIN; SOMATOMEDIN BINDING PROTEIN 2; TRIACYLGLYCEROL; GLUCOSE BLOOD LEVEL;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; CPG ISLAND; DIET INDUCED OBESITY; DNA METHYLATION; EPIGENETICS; FAT MASS; FATTY LIVER; FLUID INTAKE; FOOD INTAKE; GENETIC REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; LIPID DIET; LIPID STORAGE; LIVER TISSUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION SITE; WEIGHT GAIN; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; BLOOD; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INSULIN RESISTANCE; LIVER; METABOLISM; MIDDLE AGED; OBESITY; PATHOLOGY;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DIET, HIGH-FAT; DNA METHYLATION; FATTY LIVER; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; LIVER; MALE; MICE; MIDDLE AGED; OBESITY;

EID: 85007405478     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw121     Document Type: Article

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