The p53 family member p73 modulates the proproliferative role of IGFBP3 in short children born small for gestational age

Molecular Biology of the Cell

Volumn 26, Issue 15, 2015, Pages 2733-2741

  Marzano, Flaviana ^a   Ventura, Annamaria ^b   Caratozzolo, Mariano Francesco ^a   Aiello, Italia ^b   Mastropasqua, Francesca ^b   Brunetti, Giacomina ^b   Cavallo, Luciano ^b   Sbisà, Elisabetta ^a   Faienza, Maria Felicia ^b   Tullo, Apollonia ^a  

^a CNR   (Italy)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P73; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; DNA BINDING PROTEIN; HUMAN GROWTH HORMONE; IGFBP3 PROTEIN, HUMAN; NUCLEAR PROTEIN; P73 PROTEIN, HUMAN; SOMATOMEDIN BINDING PROTEIN 1; TUMOR PROTEIN P73; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; INVESTIGATIVE PROCEDURES; MALE; MULTIGENE FAMILY; PRIORITY JOURNAL; SMALL FOR DATE INFANT; CELL CULTURE; GENETIC TRANSFECTION; GENETICS; HCT 116 CELL LINE; HEK293 CELL LINE; INFANT; MCF-7 CELL LINE; METABOLISM; MOLECULAR GENETICS; NEWBORN; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; CELL PROLIFERATION; CELLS, CULTURED; CHILD; DNA-BINDING PROTEINS; FEMALE; GENES, P53; HCT116 CELLS; HEK293 CELLS; HUMAN GROWTH HORMONE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; MALE; MCF-7 CELLS; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; TRANSFECTION; TUMOR PROTEIN P73; TUMOR SUPPRESSOR PROTEINS;

EID: 84938946166     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-02-0105     Document Type: Article

References (37)

1. Barbieri CE, Perez CA, Johnson KN, Ely KA, Billheimer D, Pietenpol JA (2005). IGFBP-3 is a direct target of transcriptional regulation by ΔNp63α in squamous epithelium. Cancer Res 65, 2314-2320.
2. Bertino E, Spada E, Occhi L, Coscia A, Giuliani F, Gagliardi L, Gilli G, Bona G, Fabris C, De Curtis M, Milani S (2010). Neonatal anthropometric charts: the Italian neonatal study compared with other European studies. J Pediatr Gastroenterol Nutr 51, 353-361.
3. Buckbinder L, Talbott R, Velasco-Miguel S, Takenaka I, Faha B, Seizinger BR, Kley N (1995). Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 377, 646-649.
4. Butt AJ, Martin JL, Dickson KA, McDougall F, Firth SM, Baxter RC (2004). Insulin-like growth factor binding protein-3 expression is associated with growth stimulation of T47D human breast cancer cells: the role of altered epidermal growth factor signaling. J Clin Endocrinol Metab 89, 1950-1956.
5. Clayton PE, Cianfarani S, Czernichow P, Johannsson G, Rapaport R, Rogol A (2007). Management of the child born small for gestational age through to adulthood: a consensus statement of the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society. J Clin Endocrinol Metab 92, 804-109.
6. Costanzo A, Pediconi N, Narcisi A, Guerrieri F, Belloni L, Fausti F, Botti E, Levrero M (2014). TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy. FEBS Lett 588, 2590-2599.
7. Deyoung MP, Ellisen LW (2007). p63 and p73 in human cancer: defining the network. Oncogene 26, 5169-5183.
8. DiGirolamo DJ, Mukherjee A, Fulzele K, Gan Y, Cao X, Frank SJ, Clemens TL (2007). Mode of growth hormone action in osteoblasts. J Biol Chem 282, 31666-31674.
9. Faienza MF, Marzano F, Ventura AM, Wasniewska M, Valenzise M, Valletti A, Caratozzolo MF, Cornacchia S, Sbis E, Cavallo L, Tullo A (2011). Regulation of IGFBP3 gene expression in short children born small for gestational age. Growth Horm IGF Res 21, 349-355.
10. Firth SM, Baxter RC (2002). Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23, 824-854.
11. Fulco M, Costanzo A, Merlo P, Mangiacasale R, Strano S, Blandino G, Balsano C, Lavia P, Levrero M (2003). p73 is regulated by phosphorylation at the G2/M transition. J Biol Chem 278, 49196-49202.
12. Gisel A, Panetta M, Grillo G, Licciulli VF, Liuni S, Saccone C, Pesole G (2004). DNAfan: a software tool for automated extraction and analysis of user-defined sequence regions. Bioinformatics 20, 3676-3679.
13. Gottlieb E, Vousden KH (2010). p53 regulation of metabolic pathways. Cold Spring Harb Perspect Biol 2, a001040.
14. Grillo G, Licciulli F, Liuni S, Sbis E, Pesole G (2003). PatSearch: a program for the detection of patterns and structural motifs in nucleotide sequences. Nucleic Acids Res 31, 3608-3612.
15. Huynh H, Yang X, Pollak M (1996). Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells. J Biol Chem 271, 1016-1021.
16. Klammt J, Pfffle R, Werner H, Kiess W (2008). IGF signaling defects as causes of growth failure and IUGR. Trends Endocrinol Metab 19, 197-205.
17. Labarta JI, Ruiz JA, Molina I, De Arriba A, Mayayo E, Longs AF (2009). Growth and growth hormone treatment in short stature children born small for gestational age. Pediatr Endocrinol Rev 6, 350-357.
18. Lefkimmiatis K, Caratozzolo MF, Merlo P, D'Erchia AM, Navarro B, Levrero M, Sbis E, Tullo A (2009). p73 and p63 sustain cellular growth by transcriptional activation of cell cycle progression genes. Cancer Res 69, 8563-8571.
19. Leger J, Noel M, Limal JM, Czernichow P (1996). Growth factors and intrauterine growth retardation. II. Serum growth hormone, insulin-like growth factor (IGF) I, and IGF-binding protein 3 levels in children with intrauterine growth retardation compared with normal control subjects: prospective study from birth to two years of age. Study Group of IUGR. Pediatr Res 40, 101-107.
20. Liao L, Dearth RK, Zhou S, Britton OL, Lee AV, Xu J (2006). Liver-specific overexpression of the insulin-like growth factor-I enhances somatic growth and partially prevents the effects of growth hormone deficiency. Endocrinology 147, 3877-3888.
21. Longobardi L, Torello M, Buckway C, O'Rear L, Horton WA, Hwa V, Roberts CT Jr, Chiarelli F, Rosenfeld RG, Spagnoli A (2003). A novel insulin-like growth factor (IGF)-independent role for IGF binding protein-3 in mesenchymal chondroprogenitor cell apoptosis. Endocrinology 144, 1695-1702.
22. Martin JL, Weenink SM, Baxter RC (2003). Insulin-like growth factor-binding protein-3 potentiates epidermal growth factor action in MCF-10A mammary epithelial cells. Involvement of p44/42 and p38 mitogen-activated protein kinases. J Biol Chem 278, 2969-2976.
23. Menendez D, Inga A, Resnick MA (2009). The expanding universe of p53 targets. Nat Rev Cancer 9, 724-37.
24. Merlo P, Fulco M, Costanzo A, Mangiacasale R, Strano S, Blandino G, Taya Y, Lavia P, Levrero M (2005). A role of p73 in mitotic exit. J Biol Chem 280, 30354-30360.
25. Meyer G, Cabrera Socorro A, Perez Garcia CG, Martinez Millan L, Walker N, Caput D (2004). Developmental roles of p73 in Cajal-Retzius cells and cortical patterning. J Neurosci 24, 9878-9887.
26. Mohan S, Baylink DJ (2002). IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. J Endocrinol 175, 19-31.
27. Murray-Zmijewski F, Lane DP, Bourdon JC (2006). p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ 213, 962-972.
28. Nickerson T, Huynh H (1999). Vitamin D analogue EB1089-induced prostate regression is associated with increased gene expression of insulin-like growth factor binding proteins. J Endocrinol 160, 223-229.
29. Niklison-Chirou MV, Steinert JR, Agostini M, Knight RA, Dinsdale D, Cattaneo A, Mak TW, Melino G (2013). TAp73 knockout mice show morphological and functional nervous system defects associated with loss of p75 neurotrophin receptor. Proc Natl Acad Sci USA 110, 18952-18957.
30. Sbis E, Catalano D, Grillo G, Licciulli F, Turi A, Liuni S, Pesole G, De Grassi A, Caratozzolo MF, D'Erchia AM, et al. (2007). p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data. BMC Bioinformatics 8, 520.
31. Sung HY, Choi EN, Lyu D, Mook-Jung I, Ahn JH (2014). Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease. PLoS One 9, e99047.
32. Takaoka M, Smith CE, Mashiba MK, Okawa T, Andl CD, El-Deiry WS, Nakagawa H (2006). EGF-mediated regulation of IGFBP-3 determines esophageal epithelial cellular response to IGF-I. Am J Physiol Gastrointest Liver Physiol 290, 404-416.
33. Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brck W, Moll UM (2010). p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis. Cell Death Differ 17, 1816-1829.
34. Talos F, Nemajerova A, Flores ER, Petrenko O, Moll UM (2007). p73 suppresses polyploidy and aneuploidy in the absence of functional p53. Mol Cell 27, 647-659.
35. Tomasini R, Tsuchihara K, Tsuda C, Launame SK, Wilhelm M, Ruffini A, Tsao MS, Iovanna JL, Jurisicova A, Melino G, Mak TW (2009). TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci USA 106, 797-802.
36. Tullo A, Mastropasqua G, Bourdon JC, Centonze P, Gostissa M, Costanzo A, Levrero M, Del Sal G, Saccone C, Sbis E (2003). Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target. Oncogene 22, 8738-8748.
37. Vousden KH, Ryan KM (2009). p53 and metabolism. Nat Rev Cancer 9, 691-700.