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Volumn 54, Issue 1, 2017, Pages 33-38

Lymphocyte generation and population homeostasis throughout life

Author keywords

Age associated B cells (ABC); B cell generation; Homeostatic proliferation; Immune aging; T cell receptor diversity; Thymic involution

Indexed keywords

B LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR;

EID: 85006999434     PISSN: 00371963     EISSN: 15328686     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2016.10.003     Document Type: Review
Times cited : (62)

References (37)
  • 1
    • 0037425564 scopus 로고    scopus 로고
    • Mortality associated with influenza and respiratory syncytial virus in the United States
    • [1] Thompson, W.W., Shay, D.K., Weintraub, E., et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289 (2003), 179–186.
    • (2003) JAMA , vol.289 , pp. 179-186
    • Thompson, W.W.1    Shay, D.K.2    Weintraub, E.3
  • 2
    • 84888320636 scopus 로고    scopus 로고
    • Age-dependent dysregulation of innate immunity
    • [2] Shaw, A.C., Goldstein, D.R., Montgomery, R.R., Age-dependent dysregulation of innate immunity. Nat Rev Immunol 13 (2013), 875–887.
    • (2013) Nat Rev Immunol , vol.13 , pp. 875-887
    • Shaw, A.C.1    Goldstein, D.R.2    Montgomery, R.R.3
  • 3
    • 84876535364 scopus 로고    scopus 로고
    • Understanding immunosenescence to improve responses to vaccines
    • [3] Goronzy, J.J., Weyand, C.M., Understanding immunosenescence to improve responses to vaccines. Nat Immunol 14 (2013), 428–436.
    • (2013) Nat Immunol , vol.14 , pp. 428-436
    • Goronzy, J.J.1    Weyand, C.M.2
  • 4
    • 84885402793 scopus 로고    scopus 로고
    • The effect of age on thymic function
    • [4] Palmer, D.B., The effect of age on thymic function. Front Immunol, 4, 2013, 316.
    • (2013) Front Immunol , vol.4 , pp. 316
    • Palmer, D.B.1
  • 5
    • 84868208782 scopus 로고    scopus 로고
    • Impact of immune-metabolic interactions on age-related thymic demise and T cell senescence
    • [5] Dixit, V.D., Impact of immune-metabolic interactions on age-related thymic demise and T cell senescence. Semin Immunol 24 (2012), 321–330.
    • (2012) Semin Immunol , vol.24 , pp. 321-330
    • Dixit, V.D.1
  • 7
    • 2942700206 scopus 로고    scopus 로고
    • Reduction in the developmental potential of intrathymic T cell progenitors with age
    • [7] Min, H., Montecino-Rodriguez, E., Dorshkind, K., Reduction in the developmental potential of intrathymic T cell progenitors with age. J Immunol 173 (2004), 245–250.
    • (2004) J Immunol , vol.173 , pp. 245-250
    • Min, H.1    Montecino-Rodriguez, E.2    Dorshkind, K.3
  • 8
    • 70349664158 scopus 로고    scopus 로고
    • Evidence of premature immune aging in patients thymectomized during early childhood
    • [8] Sauce, D., Larsen, M., Fastenackels, S., et al. Evidence of premature immune aging in patients thymectomized during early childhood. J Clin Invest 119 (2009), 3070–3078.
    • (2009) J Clin Invest , vol.119 , pp. 3070-3078
    • Sauce, D.1    Larsen, M.2    Fastenackels, S.3
  • 9
    • 21044451726 scopus 로고    scopus 로고
    • The influence of age on T cell generation and TCR diversity
    • [9] Naylor, K., Li, G., Vallejo, A.N., et al. The influence of age on T cell generation and TCR diversity. J Immunol 174 (2005), 7446–7452.
    • (2005) J Immunol , vol.174 , pp. 7446-7452
    • Naylor, K.1    Li, G.2    Vallejo, A.N.3
  • 11
    • 84924266729 scopus 로고    scopus 로고
    • Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover
    • [11] Westera, L., van Hoeven, V., Drylewicz, J., et al. Lymphocyte maintenance during healthy aging requires no substantial alterations in cellular turnover. Aging Cell 14 (2015), 219–227.
    • (2015) Aging Cell , vol.14 , pp. 219-227
    • Westera, L.1    van Hoeven, V.2    Drylewicz, J.3
  • 12
    • 0029129542 scopus 로고
    • Emergence of oligoclonal T cell populations following therapeutic T cell depletion in rheumatoid arthritis
    • [12] Jendro, M.C., Ganten, T., Matteson, E.L., Weyand, C.M., Goronzy, J.J., Emergence of oligoclonal T cell populations following therapeutic T cell depletion in rheumatoid arthritis. Arthritis Rheum 38 (1995), 1242–1251.
    • (1995) Arthritis Rheum , vol.38 , pp. 1242-1251
    • Jendro, M.C.1    Ganten, T.2    Matteson, E.L.3    Weyand, C.M.4    Goronzy, J.J.5
  • 13
    • 20144387499 scopus 로고    scopus 로고
    • Age-dependent incidence, time course, and consequences of thymic renewal in adults
    • [13] Hakim, F.T., Memon, S.A., Cepeda, R., et al. Age-dependent incidence, time course, and consequences of thymic renewal in adults. J Clin Invest 115 (2005), 930–939.
    • (2005) J Clin Invest , vol.115 , pp. 930-939
    • Hakim, F.T.1    Memon, S.A.2    Cepeda, R.3
  • 14
    • 84857416171 scopus 로고    scopus 로고
    • Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans
    • [14] den Braber, I., Mugwagwa, T., Vrisekoop, N., et al. Maintenance of peripheral naive T cells is sustained by thymus output in mice but not humans. Immunity 36 (2012), 288–297.
    • (2012) Immunity , vol.36 , pp. 288-297
    • den Braber, I.1    Mugwagwa, T.2    Vrisekoop, N.3
  • 15
    • 84928473003 scopus 로고    scopus 로고
    • Naive T cell maintenance and function in human aging
    • [15] Goronzy, J.J., Fang, F., Cavanagh, M.M., Qi, Q., Weyand, C.M., Naive T cell maintenance and function in human aging. J Immunol 194 (2015), 4073–4080.
    • (2015) J Immunol , vol.194 , pp. 4073-4080
    • Goronzy, J.J.1    Fang, F.2    Cavanagh, M.M.3    Qi, Q.4    Weyand, C.M.5
  • 16
    • 84896501298 scopus 로고    scopus 로고
    • Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans
    • [16] Wertheimer, A.M., Bennett, M.S., Park, B., et al. Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans. J Immunol 192 (2014), 2143–2155.
    • (2014) J Immunol , vol.192 , pp. 2143-2155
    • Wertheimer, A.M.1    Bennett, M.S.2    Park, B.3
  • 17
    • 57449097558 scopus 로고    scopus 로고
    • Homeostasis of naive and memory T cells
    • [17] Surh, C.D., Sprent, J., Homeostasis of naive and memory T cells. Immunity 29 (2008), 848–862.
    • (2008) Immunity , vol.29 , pp. 848-862
    • Surh, C.D.1    Sprent, J.2
  • 18
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance
    • [18] Fry, T.J., Mackall, C.L., The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J Immunol 174 (2005), 6571–6576.
    • (2005) J Immunol , vol.174 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 19
    • 84892166251 scopus 로고    scopus 로고
    • Mathematical model of naive T cell division and survival IL-7 thresholds
    • [19] Reynolds, J., Coles, M., Lythe, G., Molina-Paris, C., Mathematical model of naive T cell division and survival IL-7 thresholds. Front Immunol, 4, 2013, 434.
    • (2013) Front Immunol , vol.4 , pp. 434
    • Reynolds, J.1    Coles, M.2    Lythe, G.3    Molina-Paris, C.4
  • 20
    • 84921634186 scopus 로고    scopus 로고
    • Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories
    • [20] Nikolich-Zugich, J., Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories. J Immunol 193 (2014), 2622–2629.
    • (2014) J Immunol , vol.193 , pp. 2622-2629
    • Nikolich-Zugich, J.1
  • 21
    • 80051970221 scopus 로고    scopus 로고
    • Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions
    • [21] Rudd, B.D., Venturi, V., Li, G., et al. Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions. Proc Natl Acad Sci U S A 108 (2011), 13694–13699.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 13694-13699
    • Rudd, B.D.1    Venturi, V.2    Li, G.3
  • 22
    • 63049091860 scopus 로고    scopus 로고
    • The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion
    • [22] Haluszczak, C., Akue, A.D., Hamilton, S.E., et al. The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion. J Exp Med 206 (2009), 435–448.
    • (2009) J Exp Med , vol.206 , pp. 435-448
    • Haluszczak, C.1    Akue, A.D.2    Hamilton, S.E.3
  • 23
    • 84976298029 scopus 로고    scopus 로고
    • Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses
    • [23] Pulko, V., Davies, J.S., Martinez, C., et al. Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses. Nat Immunol 8 (2016), 966–975.
    • (2016) Nat Immunol , vol.8 , pp. 966-975
    • Pulko, V.1    Davies, J.S.2    Martinez, C.3
  • 24
    • 84907001176 scopus 로고    scopus 로고
    • Diversity and clonal selection in the human T-cell repertoire
    • [24] Qi, Q., Liu, Y., Cheng, Y., et al. Diversity and clonal selection in the human T-cell repertoire. Proc Natl Acad Sci U S A 111 (2014), 13139–13144.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 13139-13144
    • Qi, Q.1    Liu, Y.2    Cheng, Y.3
  • 25
    • 84927635336 scopus 로고    scopus 로고
    • Long-lasting stem cell-like memory CD8+ T cells with a naive-like profile upon yellow fever vaccination
    • 282ra48
    • [25] Fuertes Marraco, S.A., Soneson, C., Cagnon, L., et al. Long-lasting stem cell-like memory CD8+ T cells with a naive-like profile upon yellow fever vaccination. Sci Transl Med, 7, 2015 282ra48.
    • (2015) Sci Transl Med , vol.7
    • Fuertes Marraco, S.A.1    Soneson, C.2    Cagnon, L.3
  • 27
    • 84870293512 scopus 로고    scopus 로고
    • Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
    • [27] Li, G., Yu, M., Lee, W.W., et al. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 18 (2012), 1518–1524.
    • (2012) Nat Med , vol.18 , pp. 1518-1524
    • Li, G.1    Yu, M.2    Lee, W.W.3
  • 28
    • 84871835297 scopus 로고    scopus 로고
    • Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
    • [28] Johnson, P.L., Yates, A.J., Goronzy, J.J., Antia, R., Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age. Proc Natl Acad Sci U S A 109 (2012), 21432–21437.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 21432-21437
    • Johnson, P.L.1    Yates, A.J.2    Goronzy, J.J.3    Antia, R.4
  • 29
    • 0032957642 scopus 로고    scopus 로고
    • Role of cytomegalovirus in the T cell changes seen in elderly individuals
    • [29] Looney, R.J., Falsey, A., Campbell, D., et al. Role of cytomegalovirus in the T cell changes seen in elderly individuals. Clin Immunol 90 (1999), 213–219.
    • (1999) Clin Immunol , vol.90 , pp. 213-219
    • Looney, R.J.1    Falsey, A.2    Campbell, D.3
  • 30
    • 32044433093 scopus 로고    scopus 로고
    • Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
    • [30] Hadrup, S.R., Strindhall, J., Kollgaard, T., et al. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J Immunol 176 (2006), 2645–2653.
    • (2006) J Immunol , vol.176 , pp. 2645-2653
    • Hadrup, S.R.1    Strindhall, J.2    Kollgaard, T.3
  • 31
    • 34447260501 scopus 로고    scopus 로고
    • The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire
    • [31] Pourgheysari, B., Khan, N., Best, D., Bruton, R., Nayak, L., Moss, P.A., The cytomegalovirus-specific CD4+ T-cell response expands with age and markedly alters the CD4+ T-cell repertoire. J Virol 81 (2007), 7759–7765.
    • (2007) J Virol , vol.81 , pp. 7759-7765
    • Pourgheysari, B.1    Khan, N.2    Best, D.3    Bruton, R.4    Nayak, L.5    Moss, P.A.6
  • 32
    • 0037103256 scopus 로고    scopus 로고
    • Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
    • [32] Khan, N., Shariff, N., Cobbold, M., et al. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol 169 (2002), 1984–1992.
    • (2002) J Immunol , vol.169 , pp. 1984-1992
    • Khan, N.1    Shariff, N.2    Cobbold, M.3
  • 33
    • 61349097791 scopus 로고    scopus 로고
    • B-cell responses to vaccination at the extremes of age
    • [33] Siegrist, C.A., Aspinall, R., B-cell responses to vaccination at the extremes of age. Nat Rev Immunol 9 (2009), 185–194.
    • (2009) Nat Rev Immunol , vol.9 , pp. 185-194
    • Siegrist, C.A.1    Aspinall, R.2
  • 34
    • 67649402297 scopus 로고    scopus 로고
    • Aging in the lympho-hematopoietic stem cell compartment
    • [34] Geiger, H., Rudolph, K.L., Aging in the lympho-hematopoietic stem cell compartment. Trends Immunol 30 (2009), 360–365.
    • (2009) Trends Immunol , vol.30 , pp. 360-365
    • Geiger, H.1    Rudolph, K.L.2
  • 36
    • 84955241577 scopus 로고    scopus 로고
    • The ageing human B cell repertoire: a failure of selection?
    • [36] Dunn-Walters, D.K., The ageing human B cell repertoire: a failure of selection?. Clin Exp Immunol 183 (2016), 50–56.
    • (2016) Clin Exp Immunol , vol.183 , pp. 50-56
    • Dunn-Walters, D.K.1
  • 37
    • 84950153720 scopus 로고    scopus 로고
    • Age-associated B cells: key mediators of both protective and autoreactive humoral responses
    • [37] Naradikian, M.S., Hao, Y., Cancro, M.P., Age-associated B cells: key mediators of both protective and autoreactive humoral responses. Immunol Rev 269 (2016), 118–129.
    • (2016) Immunol Rev , vol.269 , pp. 118-129
    • Naradikian, M.S.1    Hao, Y.2    Cancro, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.