Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines

Biomedicine and Pharmacotherapy

Volumn 86, Issue , 2017, Pages 307-315

  Erukainure, Ochuko L ^a,b,c   Choudhary, M Iqbal ^b   Adhikari, Achyut ^b   Islam, Md Shahidul ^c   Hafizur, Rahman M ^b   Mesaik, Ahmed M ^b,d   Muhammad, Aliyu ^b,g   Atolani, Olubunmi ^e,f   Banerjee, Priyanka ^e   Preissner, Robert ^e  

^a FEDERAL INSTITUTE OF INDUSTRIAL RESEARCH   (Nigeria)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF TABUK   (Saudi Arabia)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^f UNIVERSITY OF ILORIN   (Nigeria)

^g AHMADU BELLO UNIVERSITY   (Nigeria)

Author keywords

Clerodendrum volubile; Oxidative burst; Protocatechuic acid; Type 2 diabetes; Glucosidase

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIDIABETIC AGENT; CLERODENDRUM VOLUBILE EXTRACT; CYTOKINE; IMMUNOMODULATING AGENT; NICOTINAMIDE; PLANT EXTRACT; PROTOCATECHUIC ACID; STREPTOZOCIN; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; AUTACOID; HYDROXYBENZOIC ACID DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CLERODENDRUM; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; IMMUNOMODULATION; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; MALE; MOLECULAR MODEL; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NORMAL HUMAN; PHAGOCYTOSIS; PLANT LEAF; PRIORITY JOURNAL; RAT; RESPIRATORY BURST; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; T LYMPHOCYTE; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR DOCKING; PHAGOCYTE; PHYSIOLOGY; WISTAR RAT;

ACETATES; ANIMALS; CLERODENDRUM; CYTOKINES; HUMANS; HYDROXYBENZOATES; HYPOGLYCEMIC AGENTS; INFLAMMATION MEDIATORS; MALE; MOLECULAR DOCKING SIMULATION; PHAGOCYTES; PLANT EXTRACTS; RATS; RATS, WISTAR; RESPIRATORY BURST;

EID: 85006968177     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.12.035     Document Type: Article

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