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Volumn 3, Issue 3, 2015, Pages

Reduced activity of SKC a and Na-K ATPase underlies the accelerated impairment of EDH-type relaxations in mesenteric arteries of aging spontaneously hypertensive rats

Author keywords

Aging; endothelial dysfunction; endothelium derived hyperpolarization; hypertension; small conductance calcium activated potassium channel; sodium potassium ATPase

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; 6,10 DIAZA 3(1,3)8,(1,4) DIBENZENA 1,5(1,4) DIQUINOLINACYCLODECAPHANE; ACETYLCHOLINE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BARIUM CHLORIDE; ENDOTHELIUM DERIVED RELAXING FACTOR; INDOMETACIN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; OUABAIN; PHENYLEPHRINE; SIRTUIN 1; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

EID: 85006575352     PISSN: None     EISSN: 20521707     Source Type: Journal    
DOI: 10.1002/prp2.150     Document Type: Article
Times cited : (25)

References (55)
  • 2
    • 0037160097 scopus 로고    scopus 로고
    • Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
    • Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, Sinclair DA (2002). Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 227: 45009–45107.
    • (2002) J Biol Chem , vol.227 , pp. 45009-45107
    • Bitterman, K.J.1    Anderson, R.M.2    Cohen, H.Y.3    Latorre-Esteves, M.4    Sinclair, D.A.5
  • 4
    • 0141893558 scopus 로고    scopus 로고
    • Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery
    • Büssemaker E, Popp R, Fisslthaler B, Larson CM, Fleming I, Busse R, et al. (2003). Aged spontaneously hypertensive rats exhibit a selective loss of EDHF-mediated relaxation in the renal artery. Hypertension 42: 562–568.
    • (2003) Hypertension , vol.42 , pp. 562-568
    • Büssemaker, E.1    Popp, R.2    Fisslthaler, B.3    Larson, C.M.4    Fleming, I.5    Busse, R.6
  • 5
    • 0031786851 scopus 로고    scopus 로고
    • Impaired endothelial regulation of vascular tone in patients with systemic arterial hypertension
    • Cardillo C, Panza JA (1998). Impaired endothelial regulation of vascular tone in patients with systemic arterial hypertension. Vasc Med 3: 138–144.
    • (1998) Vasc Med , vol.3 , pp. 138-144
    • Cardillo, C.1    Panza, J.A.2
  • 6
    • 0031984877 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids, potassium channel blockers and endothelium-dependent hyperpolarization in the guinea-pig carotid artery
    • Chataigneau T, Félétou M, Duhault J, Vanhoutte PM (1998). Epoxyeicosatrienoic acids, potassium channel blockers and endothelium-dependent hyperpolarization in the guinea-pig carotid artery. Br J Pharmacol 123: 574–580.
    • (1998) Br J Pharmacol , vol.123 , pp. 574-580
    • Chataigneau, T.1    Félétou, M.2    Duhault, J.3    Vanhoutte, P.M.4
  • 7
    • 0032522387 scopus 로고    scopus 로고
    • Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries
    • Chaytor AT, Evans WH, Griffith TM (1998). Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol 508: 561–573.
    • (1998) J Physiol , vol.508 , pp. 561-573
    • Chaytor, A.T.1    Evans, W.H.2    Griffith, T.M.3
  • 8
    • 0029962654 scopus 로고    scopus 로고
    • Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig
    • Corriu C, Félétou M, Canet E, Vanhoutte PM (1996). Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig. Br J Pharmacol 119: 959–964.
    • (1996) Br J Pharmacol , vol.119 , pp. 959-964
    • Corriu, C.1    Félétou, M.2    Canet, E.3    Vanhoutte, P.M.4
  • 9
    • 55449136486 scopus 로고    scopus 로고
    • Inflammation and endothelial dysfunction during aging: role of NF-kappaB
    • Csiszar A, Wang M, Lakatta EG, Ungvari Z (2008). Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol 105: 1333–1341.
    • (2008) J Appl Physiol , vol.105 , pp. 1333-1341
    • Csiszar, A.1    Wang, M.2    Lakatta, E.G.3    Ungvari, Z.4
  • 11
    • 77953257025 scopus 로고    scopus 로고
    • Aging and disease: connections to sirtuins
    • Donmez G, Guarente L (2010). Aging and disease: connections to sirtuins. Aging Cell 9: 285–290.
    • (2010) Aging Cell , vol.9 , pp. 285-290
    • Donmez, G.1    Guarente, L.2
  • 13
    • 0033946196 scopus 로고    scopus 로고
    • Potassium does not mimic EDHF in rat mesenteric arteries
    • Doughty JM, Boyle JP, Langton PD (2000). Potassium does not mimic EDHF in rat mesenteric arteries. Br J Pharmacol 130: 1174–1182.
    • (2000) Br J Pharmacol , vol.130 , pp. 1174-1182
    • Doughty, J.M.1    Boyle, J.P.2    Langton, P.D.3
  • 14
    • 0032548099 scopus 로고    scopus 로고
    • K+ is an endothelium-derived hyperpolarizing factor in rat arteries
    • Edwards G, Dora KA, Gardener MJ, Garland CJ, Weston AH (1998). K+ is an endothelium-derived hyperpolarizing factor in rat arteries. Nature 396: 269–272.
    • (1998) Nature , vol.396 , pp. 269-272
    • Edwards, G.1    Dora, K.A.2    Gardener, M.J.3    Garland, C.J.4    Weston, A.H.5
  • 15
    • 77955292086 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarising factors and associated pathways: a synopsis
    • Edwards G, Félétou M, Weston AH (2010). Endothelium-derived hyperpolarising factors and associated pathways: a synopsis. Pflügers Arch 459: 863–879.
    • (2010) Pflügers Arch , vol.459 , pp. 863-879
    • Edwards, G.1    Félétou, M.2    Weston, A.H.3
  • 16
    • 84903190232 scopus 로고    scopus 로고
    • Endothelial AMP-activated protein kinase regulates blood pressure and coronary flow responses through hyperpolarization mechanism in mice
    • Enkhjargal B, Godo S, Sawada A, Suvd N, Saito H, Noda K, et al. (2014). Endothelial AMP-activated protein kinase regulates blood pressure and coronary flow responses through hyperpolarization mechanism in mice. Arterioscler Thromb Vasc Biol 34: 1505–1513.
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 1505-1513
    • Enkhjargal, B.1    Godo, S.2    Sawada, A.3    Suvd, N.4    Saito, H.5    Noda, K.6
  • 17
    • 58849155179 scopus 로고    scopus 로고
    • Vascular endothelial senescence: from mechanisms to pathophysiology
    • Erusalimsky JD (2009). Vascular endothelial senescence: from mechanisms to pathophysiology. J Appl Physiol 106: 326–332.
    • (2009) J Appl Physiol , vol.106 , pp. 326-332
    • Erusalimsky, J.D.1
  • 18
    • 33748421398 scopus 로고    scopus 로고
    • Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture)
    • Félétou M, Vanhoutte PM (2006). Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). Am J Physiol Heart Circ Physiol 291: H985–H1002.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H985-H1002
    • Félétou, M.1    Vanhoutte, P.M.2
  • 19
    • 35748931462 scopus 로고    scopus 로고
    • Endothelium-dependent hyperolarizations: past beliefs and present facts
    • Félétou M, Vanhoutte PM (2007). Endothelium-dependent hyperolarizations: past beliefs and present facts. Annals of Med 39: 495–516.
    • (2007) Annals of Med , vol.39 , pp. 495-516
    • Félétou, M.1    Vanhoutte, P.M.2
  • 21
    • 68049103917 scopus 로고    scopus 로고
    • Activation and signaling by the AMP-activated protein kinase in endothelial cells
    • Fisslthaler B, Fleming I (2009). Activation and signaling by the AMP-activated protein kinase in endothelial cells. Circ Res 105: 114–127.
    • (2009) Circ Res , vol.105 , pp. 114-127
    • Fisslthaler, B.1    Fleming, I.2
  • 22
    • 84858702507 scopus 로고    scopus 로고
    • AMP-activated protein kinase activator AICAR acutely lowers blood pressure and relaxes isolated resistance arteries of hypertensive rats
    • Ford RJ, Teschke SR, Reid B, Durham KK, Kroetsch JT, Rush JWE (2012). AMP-activated protein kinase activator AICAR acutely lowers blood pressure and relaxes isolated resistance arteries of hypertensive rats. J Hypertens 30: 725–733.
    • (2012) J Hypertens , vol.30 , pp. 725-733
    • Ford, R.J.1    Teschke, S.R.2    Reid, B.3    Durham, K.K.4    Kroetsch, J.T.5    Rush, J.W.E.6
  • 23
    • 0024390169 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • Furchgott RF, Vanhoutte PM (1989). Endothelium-derived relaxing and contracting factors. FASEB J 3: 2007–2018.
    • (1989) FASEB J , vol.3 , pp. 2007-2018
    • Furchgott, R.F.1    Vanhoutte, P.M.2
  • 24
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV (1980). The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373–376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 25
    • 70249130135 scopus 로고    scopus 로고
    • Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats
    • Giachini FR, Carneiro FS, Lima VV, Carneiro ZN, Dorrance A, Webb RC, et al. (2009). Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats. Transl Res 154: 183–193.
    • (2009) Transl Res , vol.154 , pp. 183-193
    • Giachini, F.R.1    Carneiro, F.S.2    Lima, V.V.3    Carneiro, Z.N.4    Dorrance, A.5    Webb, R.C.6
  • 26
    • 14844289539 scopus 로고    scopus 로고
    • Role of SK(Ca) and IK(Ca) in endothelium-dependent hyperpolarizations of the guinea-pig isolated carotid artery
    • Gluais P, Edwards G, Weston AH, Falck JR, Vanhoutte PM, Félétou M (2005a). Role of SK(Ca) and IK(Ca) in endothelium-dependent hyperpolarizations of the guinea-pig isolated carotid artery. Br J Pharmacol 144: 477–485.
    • (2005) Br J Pharmacol , vol.144 , pp. 477-485
    • Gluais, P.1    Edwards, G.2    Weston, A.H.3    Falck, J.R.4    Vanhoutte, P.M.5    Félétou, M.6
  • 27
    • 27744564624 scopus 로고    scopus 로고
    • Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin
    • Gluais P, Lonchampt M, Morrow JD, Vanhoutte PM, Feletou M (2005b). Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. Br J Pharmacol 146: 834–845.
    • (2005) Br J Pharmacol , vol.146 , pp. 834-845
    • Gluais, P.1    Lonchampt, M.2    Morrow, J.D.3    Vanhoutte, P.M.4    Feletou, M.5
  • 28
    • 0019826525 scopus 로고
    • Aortic endothelial and subendothelial cells in experimental hypertension and aging
    • Haudenschild CC, Prescott MF, Chobanian AV (1981). Aortic endothelial and subendothelial cells in experimental hypertension and aging. Hypertension 3(Suppl. I): I148–I153.
    • (1981) Hypertension , vol.3 , pp. I148-I153
    • Haudenschild, C.C.1    Prescott, M.F.2    Chobanian, A.V.3
  • 29
    • 0029132074 scopus 로고
    • Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors
    • Lang MG, Noll G, Lüscher TF (1995). Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors. Am J Physiol 269: H837–H844.
    • (1995) Am J Physiol , vol.269 , pp. H837-H844
    • Lang, M.G.1    Noll, G.2    Lüscher, T.F.3
  • 30
    • 84865860473 scopus 로고    scopus 로고
    • Endothelium-selective activation of AMP-activated protein kinase prevents diabetes mellitus-induced impairment in vascular function and reendothelialization via induction of heme oxygenase-1 in mice
    • Li FY, Lam KS, Tse HF, Chen C, Wang Y, Vanhoutte PM, et al. (2012). Endothelium-selective activation of AMP-activated protein kinase prevents diabetes mellitus-induced impairment in vascular function and reendothelialization via induction of heme oxygenase-1 in mice. Circulation 126: 1267–1277.
    • (2012) Circulation , vol.126 , pp. 1267-1277
    • Li, F.Y.1    Lam, K.S.2    Tse, H.F.3    Chen, C.4    Wang, Y.5    Vanhoutte, P.M.6
  • 31
    • 84887590359 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat
    • Li Z, Wang Y, Man RYK, Vanhoutte PM (2013). Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol 305: H1474–H1483.
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , pp. H1474-H1483
    • Li, Z.1    Wang, Y.2    Man, R.Y.K.3    Vanhoutte, P.M.4
  • 32
    • 83155175257 scopus 로고    scopus 로고
    • Upregulation of heme oxygenase 1 by hemin impairs endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat
    • Li Z, Wang Y, Vanhoutte PM (2011). Upregulation of heme oxygenase 1 by hemin impairs endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat. Hypertension 58: 926–934.
    • (2011) Hypertension , vol.58 , pp. 926-934
    • Li, Z.1    Wang, Y.2    Vanhoutte, P.M.3
  • 34
    • 0022545417 scopus 로고
    • Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat
    • Lüscher TF, Vanhoutte PM (1986). Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 8: 344–348.
    • (1986) Hypertension , vol.8 , pp. 344-348
    • Lüscher, T.F.1    Vanhoutte, P.M.2
  • 35
    • 0028918559 scopus 로고
    • Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension
    • Mantelli L, Amerini S, Ledda F (1995). Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension. J Cardiovasc Pharmacol 25: 595–602.
    • (1995) J Cardiovasc Pharmacol , vol.25 , pp. 595-602
    • Mantelli, L.1    Amerini, S.2    Ledda, F.3
  • 36
    • 35549008884 scopus 로고    scopus 로고
    • SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
    • Mattagajasingh I, Kim CS, Naqvi A, Yamamori T, Hoffman TA, Jung SB, et al. (2007). SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase. Proc Natl Acad Sci USA 104: 14855–14860.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14855-14860
    • Mattagajasingh, I.1    Kim, C.S.2    Naqvi, A.3    Yamamori, T.4    Hoffman, T.A.5    Jung, S.B.6
  • 37
    • 9144223017 scopus 로고    scopus 로고
    • Pivotal role of Cu, Zn-superoxide dismutase in endothelium-dependent hyperpolarization
    • Morikawa K, Shimokawa H, Matoba T, Kubota H, Akaike T, Talukder MA, et al. (2003). Pivotal role of Cu, Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest 112: 1871–1189.
    • (2003) J Clin Invest , vol.112 , pp. 1189-1871
    • Morikawa, K.1    Shimokawa, H.2    Matoba, T.3    Kubota, H.4    Akaike, T.5    Talukder, M.A.6
  • 38
    • 2942564591 scopus 로고    scopus 로고
    • Sirtuins: Sir2-related NAD-dependent protein deacetylases
    • North BJ, Verdin E (2004). Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol 5: 224. doi:10.1186/gb-2004-5-5-224
    • (2004) Genome Biol , vol.5 , pp. 224
    • North, B.J.1    Verdin, E.2
  • 39
    • 80052638751 scopus 로고    scopus 로고
    • Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells
    • Orecchia A, Scarponi C, Di Felice F, Cesarini E, Avitabile S, Mai A, et al. (2011). Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells. PLoS ONE 6: e24307.
    • (2011) PLoS ONE , vol.6
    • Orecchia, A.1    Scarponi, C.2    Di Felice, F.3    Cesarini, E.4    Avitabile, S.5    Mai, A.6
  • 40
    • 35349011597 scopus 로고    scopus 로고
    • Sirt1 modulates premature senescence-like phenotype in human endothelial cells
    • Ota H, Akishita M, Eto M, Iijima K, Kaneki M, Ouchi Y (2007). Sirt1 modulates premature senescence-like phenotype in human endothelial cells. J Mol Cell Cardiol 43: 571–579.
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 571-579
    • Ota, H.1    Akishita, M.2    Eto, M.3    Iijima, K.4    Kaneki, M.5    Ouchi, Y.6
  • 41
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrigo AG, Moncada S (1987). Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524–525.
    • (1987) Nature , vol.327 , pp. 524-525
    • Palmer, R.M.1    Ferrigo, A.G.2    Moncada, S.3
  • 42
    • 84901369802 scopus 로고    scopus 로고
    • Probiotics (VSL#3) prevent endothelial dysfunction in rats with portal hypertension: role of the angiotensin system
    • Rashid SK, Khodja NI, Auger C, Alhosin M, Boehm N, Oswald-Mammosser M, et al. (2014). Probiotics (VSL#3) prevent endothelial dysfunction in rats with portal hypertension: role of the angiotensin system. PLoS ONE 9: e97458.
    • (2014) PLoS ONE , vol.9
    • Rashid, S.K.1    Khodja, N.I.2    Auger, C.3    Alhosin, M.4    Boehm, N.5    Oswald-Mammosser, M.6
  • 43
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees DD, Palmer RMJ, Schulz R, Hodson HF, Moncada S (1990). Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 101: 746–752.
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.J.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 44
    • 26844579374 scopus 로고    scopus 로고
    • Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in animals and humans
    • Shimokawa H, Morikawa K (2005). Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in animals and humans. J Mol Cell Cardiol 39: 725–732.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 725-732
    • Shimokawa, H.1    Morikawa, K.2
  • 45
    • 0027952841 scopus 로고
    • Changes in the endothelial cyclooxygenase pathway in resistance arteries of spontaneously hypertensive rats
    • Takase H, Dohi Y, Kojima M, Sato K (1994). Changes in the endothelial cyclooxygenase pathway in resistance arteries of spontaneously hypertensive rats. J Cardiovasc Pharmacol 23: 326–330.
    • (1994) J Cardiovasc Pharmacol , vol.23 , pp. 326-330
    • Takase, H.1    Dohi, Y.2    Kojima, M.3    Sato, K.4
  • 47
    • 50849119073 scopus 로고    scopus 로고
    • Mechanism of thrombin mediated eNOS phosphorylation in endothelial cells is dependent on ATP levels after stimulation
    • Thors B, Halldórsson H, Jónsdóttir G, Thorgeirsson G (2008). Mechanism of thrombin mediated eNOS phosphorylation in endothelial cells is dependent on ATP levels after stimulation. Biochim Biophys Acta 1783: 1893–1902.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1893-1902
    • Thors, B.1    Halldórsson, H.2    Jónsdóttir, G.3    Thorgeirsson, G.4
  • 49
    • 0028289695 scopus 로고
    • Contribution of both nitric oxide and a change in membrane potential to acetylcholine-induced relaxation in the rat small mesenteric artery
    • Waldron GJ, Garland CJ (1994). Contribution of both nitric oxide and a change in membrane potential to acetylcholine-induced relaxation in the rat small mesenteric artery. Br J Pharmacol 112: 831–836.
    • (1994) Br J Pharmacol , vol.112 , pp. 831-836
    • Waldron, G.J.1    Garland, C.J.2
  • 50
    • 79953239122 scopus 로고    scopus 로고
    • SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model
    • Wang Y, Liang Y, Vanhoutte PM (2011). SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model. FEBS Lett 585: 986–994.
    • (2011) FEBS Lett , vol.585 , pp. 986-994
    • Wang, Y.1    Liang, Y.2    Vanhoutte, P.M.3
  • 51
    • 77952816888 scopus 로고    scopus 로고
    • Ca channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats
    • Ca channels and of downstream hyperpolarizing pathways in mesenteric arteries from spontaneously hypertensive rats. Br J Pharmacol 160: 836–843.
    • (2010) Br J Pharmacol , vol.160 , pp. 836-843
    • Weston, A.H.1    Porter, E.L.2    Harno, E.3    Edwards, G.4
  • 52
    • 77958035114 scopus 로고    scopus 로고
    • Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat
    • Wong MS, Delansorne R, Man RY, Svenningsen P, Vanhoutte PM (2010). Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol 299: H1226–H1234.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. H1226-H1234
    • Wong, M.S.1    Delansorne, R.2    Man, R.Y.3    Svenningsen, P.4    Vanhoutte, P.M.5
  • 53
    • 84886400720 scopus 로고    scopus 로고
    • Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries
    • Yeung YYT, Lee SS, Vanhoutte PM, Leung SWS (2013). Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries. J Cardiovasc Pharmacol 62: 397–404.
    • (2013) J Cardiovasc Pharmacol , vol.62 , pp. 397-404
    • Yeung, Y.Y.T.1    Lee, S.S.2    Vanhoutte, P.M.3    Leung, S.W.S.4
  • 54
    • 84861534729 scopus 로고    scopus 로고
    • Activation of nicotinic receptors can contribute to endothelium-dependent relaxations to acetylcholine in the rat aorta
    • Zou Q, Leung SW, Vanhoutte PM (2010). Activation of nicotinic receptors can contribute to endothelium-dependent relaxations to acetylcholine in the rat aorta. J Pharmacol Exp Ther 341: 756–763.
    • (2010) J Pharmacol Exp Ther , vol.341 , pp. 756-763
    • Zou, Q.1    Leung, S.W.2    Vanhoutte, P.M.3
  • 55
    • 77952496696 scopus 로고    scopus 로고
    • SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells
    • Zu Y, Liu L, Lee MYK, Xu C, Liang Y, Man RYK, et al. (2010). SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells. Circ Res 106: 1384–1393.
    • (2010) Circ Res , vol.106 , pp. 1384-1393
    • Zu, Y.1    Liu, L.2    Lee, M.Y.K.3    Xu, C.4    Liang, Y.5    Man, R.Y.K.6


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