Upregulation of heme oxygenase 1 by hemin impairs endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat

Hypertension

Volumn 58, Issue 5, 2011, Pages 926-934

  Li, Zhuoming ^a   Wang, Yu ^a   Vanhoutte, Paul M ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b Chonbuk National University   (South Korea)

Author keywords

Endothelial dysfunction; Endothelium dependent contractions; Heme oxygenase 1; Hemin; Prostacyclin; Reactive oxygen species; Spontaneously hypertensive rat; Thromboxane prostanoid receptor

Indexed keywords

ACETYLCHOLINE; BILIRUBIN; CALCIUM IONOPHORE; CARBON MONOXIDE; CYCLOOXYGENASE 1; DICHLORODIHYDROFLUORESCEIN DIACETATE; HEME OXYGENASE 1; HEMIN; HYDROETHIDINE; ILOPROST; LUCIGENIN; PROSTACYCLIN; PROSTANOID RECEPTOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; THROMBOXANE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TEMPERATURE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HEME OXYGENASE-1; HEMIN; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; OXIDATIVE STRESS; PROSTAGLANDINS; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; UP-REGULATION;

EID: 83155175257     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.173807     Document Type: Article

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