Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode

Bioelectrochemistry

Volumn 114, Issue , 2017, Pages 24-32

  Khoshfetrat, Seyyed Mehdi ^a   Mehrgardi, Masoud A ^a  

^a UNIVERSITY OF ISFAHAN   (Iran)

Author keywords

Aptamer; Cancer cell; CCRF CEM; Gold coated magnetic nanoparticle; Nitrogen doped graphene

Indexed keywords

DOPING (ADDITIVES); ELECTRODES; GOLD; GOLD COATINGS; GRAPHENE; MAGNETISM; NANOMAGNETICS; NANOPARTICLES; NITROGEN;

APTAMERS; CANCER CELLS; CCRF-CEM; MAGNETIC NANO-PARTICLES; NITROGEN DOPED GRAPHENE;

DISEASES;

APTAMER; ETHIDIUM BROMIDE; GOLD NANOPARTICLE; GRAPHENE; MAGNETIC NANOPARTICLE; NANOSHEET; NITROGEN; GOLD; GRAPHITE; MAGNETITE NANOPARTICLE; METAL NANOPARTICLE;

ARTICLE; BIOSENSOR; CANCER DIAGNOSIS; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; ELECTRODE; HUMAN; HUMAN CELL; IMMOBILIZATION; LEUKEMIA; LEUKEMIA CELL; QUANTITATIVE ANALYSIS; CHEMISTRY; DEVICES; ELECTROCHEMISTRY; GENETIC PROCEDURES; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PH; PROCEDURES; TIME FACTOR; TUMOR CELL LINE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BIOSENSING TECHNIQUES; CELL LINE, TUMOR; ELECTROCHEMISTRY; ELECTRODES; GOLD; GRAPHITE; HUMANS; HYDROGEN-ION CONCENTRATION; LEUKEMIA; MAGNETITE NANOPARTICLES; METAL NANOPARTICLES; NITROGEN; TIME FACTORS;

EID: 85006470304     PISSN: 15675394     EISSN: 1878562X     Source Type: Journal    
DOI: 10.1016/j.bioelechem.2016.12.001     Document Type: Article

References (76)

1. [1] Meng, H.-M., Liu, H., Kuai, H., Peng, R., Mo, L., Zhang, X.-B., Aptamer-integrated, D.N.A., Nanostructures for biosensing, bioimaging and cancer therapy. Chem. Soc. Rev. 45 (2016), 2583–2602.
2. [2] Gavai, A.V., Quesnelle, C., Norris, D., Han, W.-C., Gill, P., Shan, W., Balog, A., Chen, K., Tebben, A., Rampulla, R., Wu, D.-R., Zhang, Y., Mathur, A., White, R., Rose, A., Wang, H., Yang, Z., Ranasinghe, A., D'Arienzo, C., Guarino, V., Xiao, L., Su, C., Everlof, G., Arora, V., Shen, D.R., Cvijic, M.E., Menard, K., Wen, M.-L., Meredith, J., Trainor, G., Lombardo, L.J., Olson, R., Baran, P.S., Hunt, J.T., Vite, G.D., Fischer, B.S., Westhouse, R.A., Lee, F.Y., Discovery of clinical candidate BMS-906024: a potent pan-notch inhibitor for the treatment of leukemia and solid tumors. ACS Med. Chem. Lett. 6 (2015), 523–527.
3. [3] Dupuis, J., Brice, P., François, S., Ysebaert, L., de Guibert, S., Levy, V., Leprêtre, S., Choquet, S., Dilhuydy, M.S., Fornecker, L., Morel, V., Tempescul, A., Ofatumumab in refractory chronic lymphocytic leukemia: experience through the French early access program. Clin. Lymphoma Myeloma Leuk. 15 (2015), e43–e46.
4. [4] Hourigan, C.S., Karp, J.E., Minimal residual disease in acute myeloid leukaemia. Nat. Rev. Clin. Oncol. 10 (2013), 460–471.
5. [5] Paredes-Aguilera, R., Romero-Guzman, L., Lopez-Santiago, N., Burbano-Ceron, L., Monte, C.D., Nieto-Martinez, S., Flow cytometric analysis of cell-surface and intracellular antigens in the diagnosis of acute leukemia. Am. J. Hematol. 68 (2001), 69–74.
6. [6] Ghossein, R., Bhattacharya, S., Molecular detection and characterisation of circulating tumour cells and micrometastases in solid tumours. Eur. J. Cancer 36 (2000), 1681–1694.
7. [7] Belov, L., de la Vega, O., dos Remedios, C.G., Mulligan, S.P., Christopherson, R.I., Immunophenotyping of leukemias using a cluster of differentiation antibody microarray. Cancer Res. 61 (2001), 4483–4489.
8. [8] Dewald, G.W., Brockman, S.R., Paternoster, S.F., Bone, N.D., O'Fallon, J.R., Allmer, C., James, C.D., Jelinek, D.F., Tschumper, R.C., Hanson, C.A., Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia. Br. J. Haematol. 121 (2003), 287–295.
9. [9] Singh, S.K., Hawkins, C., Clarke, I.D., Squire, J.A., Bayani, J., Hide, T., Henkelman, R.M., Cusimano, M.D., Dirks, P.B., Identification of human brain tumour initiating cells. Nature 432 (2004), 396–401.
10. [10] Ley, T.J., Mardis, E.R., Ding, L., Fulton, B., McLellan, M.D., Chen, K., Dooling, D., Dunford-Shore, B.H., McGrath, S., Hickenbotham, M., DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456 (2008), 66–72.
11. [11] Khoshfetrat, S.M., Mehrgardi, M.A., Dual amplification of single nucleotide polymorphism detection using graphene oxide and nanoporous gold electrode platform. Analyst 139 (2014), 5192–5199.
12. [12] Aznar-Cervantes, S., Martínez, J.G., Bernabeu-Esclapez, A., Lozano-Pérez, A.A., Meseguer-Olmo, L., Otero, T.F., Cenis, J.L., Fabrication of electrospun silk fibroin scaffolds coated with graphene oxide and reduced graphene for applications in biomedicine. Bioelectrochemistry 108 (2016), 36–45.
13. [13] Zhang, L., Xia, J., Zhao, Q., Liu, L., Zhang, Z., Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs. Small 6 (2010), 537–544.
14. [14] Wang, X., Han, Q., Yu, N., Li, J., Yang, L., Yang, R., Wang, C., Aptamer-conjugated graphene oxide-gold nanocomposites for targeted chemo-photothermal therapy of cancer cells. J. Mater. Chem. B 3 (2015), 4036–4042.
15. [15] Yang, K., Hu, L., Ma, X., Ye, S., Cheng, L., Shi, X., Li, C., Li, Y., Liu, Z., Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles. Adv. Mater. 24 (2012), 1868–1872.
16. [16] Akhavan, O., Ghaderi, E., Rahighi, R., Abdolahad, M., Spongy graphene electrode in electrochemical detection of leukemia at single-cell levels. Carbon 79 (2014), 654–663.
17. [17] Heerema, S.J., Dekker, C., Graphene nanodevices for DNA sequencing. Nat. Nanotechnol. 11 (2016), 127–136.
18. [18] Khoshfetrat, S.M., Mehrgardi, M.A., Amplified electrochemical genotyping of single-nucleotide polymorphisms using a graphene–gold nanoparticles modified glassy carbon platform. RSC Adv. 5 (2015), 29285–29293.
19. [19] Nandini, S., Nalini, S., Reddy, M.B.M., Suresh, G.S., Melo, J.S., Niranjana, P., Sanetuntikul, J., Shanmugam, S., Synthesis of one-dimensional gold nanostructures and the electrochemical application of the nanohybrid containing functionalized graphene oxide for cholesterol biosensing. Bioelectrochemistry 110 (2016), 79–90.
20. [20] Bonaccorso, F., Colombo, L., Yu, G., Stoller, M., Tozzini, V., Ferrari, A.C., Ruoff, R.S., Pellegrini, V., Graphene, related two-dimensional crystals, and hybrid systems for energy conversion and storage. Science, 347, 2015, 1246501.
21. [21] Wang, X., Sun, G., Routh, P., Kim, D.-H., Huang, W., Chen, P., Heteroatom-doped graphene materials: syntheses, properties and applications. Chem. Soc. Rev. 43 (2014), 7067–7098.
22. [22] Deng, D., Pan, X., Yu, L., Cui, Y., Jiang, Y., Qi, J., Li, W.-X., Fu, Q., Ma, X., Xue, Q., Toward N-doped graphene via solvothermal synthesis. Chem. Mater. 23 (2011), 1188–1193.
23. [23] Wang, H., Maiyalagan, T., Wang, X., Review on recent progress in nitrogen-doped graphene: synthesis, characterization, and its potential applications. ACS Catal. 2 (2012), 781–794.
24. [24] Wen, Q., Wang, S., Yan, J., Cong, L., Chen, Y., Xi, H., Porous nitrogen-doped carbon nanosheet on graphene as metal-free catalyst for oxygen reduction reaction in air-cathode microbial fuel cells. Bioelectrochemistry 95 (2014), 23–28.
25. [25] Barsan, M.M., David, M., Florescu, M., Ţugulea, L., Brett, C.M.A., A new self-assembled layer-by-layer glucose biosensor based on chitosan biopolymer entrapped enzyme with nitrogen doped graphene. Bioelectrochemistry 99 (2014), 46–52.
26. [26] Du, D., Ju, H., Zhang, X., Chen, J., Cai, J., Chen, H., Electrochemical immunoassay of membrane P-glycoprotein by immobilization of cells on gold nanoparticles modified on a methoxysilyl-terminated butyrylchitosan matrix. Biochemistry 44 (2005), 11539–11545.
27. [27] Li, H., Chen, J., Han, S., Niu, W., Liu, X., Xu, G., Electrochemiluminescence from tris (2, 2′-bipyridyl) ruthenium (II)–graphene–Nafion modified electrode. Talanta 79 (2009), 165–170.
28. [28] Ding, L., Hao, C., Xue, Y., Ju, H., A bio-inspired support of gold nanoparticles-chitosan nanocomposites gel for immobilization and electrochemical study of K562 leukemia cells. Biomacromolecules 8 (2007), 1341–1346.
29. [29] Wu, X., Jiang, H., Zheng, J., Wang, X., Gu, Z., Chen, C., Highly sensitive recognition of cancer cells by electrochemical biosensor based on the interface of gold nanoparticles/polylactide nanocomposites. J. Electroanal. Chem. 656 (2011), 174–178.
30. [30] Hao, C., Ding, L., Zhang, X., Ju, H., Biocompatible conductive architecture of carbon nanofiber-doped chitosan prepared with controllable electrodeposition for cytosensing. Anal. Chem. 79 (2007), 4442–4447.
31. [31] Wu, X., Jiang, H., Zhou, Y., Li, J., Wu, C., Wu, C., Chen, B., Wang, X., Selective determination of drug resistant cancer cells on indium tin oxide electrode modified with nano titanium dioxide. Electrochem. Commun. 12 (2010), 962–965.
32. [32] Chen, M., Bi, S., Jia, X., He, P., Aptamer-conjugated bio-bar-code Au–Fe 3 O 4 nanoparticles as amplification station for electrochemiluminescence detection of tumor cells. Anal. Chim. Acta 837 (2014), 44–51.
33. [33] Zhang, K., Tan, T., Fu, J.-J., Zheng, T., Zhu, J.-J., A novel aptamer-based competition strategy for ultrasensitive electrochemical detection of leukemia cells. Analyst 138 (2013), 6323–6330.
34. [34] Pan, Y., Guo, M., Nie, Z., Huang, Y., Pan, C., Zeng, K., Zhang, Y., Yao, S., Selective collection and detection of leukemia cells on a magnet-quartz crystal microbalance system using aptamer-conjugated magnetic beads. Biosens. Bioelectron. 25 (2010), 1609–1614.
35. [35] Tombácz, E., Turcu, R., Socoliuc, V., Vékás, L., Magnetic iron oxide nanoparticles: recent trends in design and synthesis of magnetoresponsive nanosystems. Biochem. Biophys. Res. Commun. 468 (2015), 442–453.
36. [36] Liu, H., Zhang, J., Chen, X., Du, X.S., Zhang, J.L., Liu, G., Zhang, W.G., Application of iron oxide nanoparticles in glioma imaging and therapy: from bench to bedside. Nanoscale 8 (2016), 7808–7826.
37. [37] Li, D., Teoh, W.Y., Gooding, J.J., Selomulya, C., Amal, R., Functionalization strategies for protease immobilization on magnetic nanoparticles. Adv. Funct. Mater. 20 (2010), 1767–1777.
38. [38] Hamidi-Asl, E., Raoof, J.B., Hejazi, M.S., Sharifi, S., Golabi, S.M., Palchetti, I., Mascini, M., Genosensor, A., For point mutation detection of P53 Gene PCR product using magnetic particles. Electroanalysis 27 (2015), 1378–1386.
39. [39] Zeng, H., Sun, S., Syntheses, properties, and potential applications of multicomponent magnetic nanoparticles. Adv. Funct. Mater. 18 (2008), 391–400.
40. [40] Bettazzi, F., Enayati, L., Sánchez, I.C., Motaghed, R., Mascini, M., Palchetti, I., Electrochemical bioassay for the detection of TNF-α using magnetic beads and disposable screen-printed array of electrodes. Bioanalysis 5 (2013), 11–19.
41. [41] Jeong, U., Teng, X., Wang, Y., Yang, H., Xia, Y., Superparamagnetic colloids: controlled synthesis and niche applications. Adv. Mater. 19 (2007), 33–60.
42. [42] Al-Khafaji, Q.A.M., Tombelli, S., Laschi, S., Marrazza, G., Mascini, M., Mohammed, N.A.M., Detection of a tumor marker in serum by an electrochemical assay coupled to magnetic beads. Lecture Notes in Electrical Engineering, 2011, 157–161.
43. [43] Shin, T.H., Choi, Y., Kim, S., Cheon, J., Recent advances in magnetic nanoparticle-based multi-modal imaging. Chem. Soc. Rev. 44 (2015), 4501–4516.
44. [44] Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., Muller, R.N., Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem. Rev. 108 (2008), 2064–2110.
45. [45] Majetich, S.A., Wen, T., Booth, R.A., Functional magnetic nanoparticle assemblies: formation, collective behavior, and future directions. ACS Nano 5 (2011), 6081–6084.
46. [46] Aguilar-Arteaga, K., Rodriguez, J., Barrado, E., Magnetic solids in analytical chemistry: a review. Anal. Chim. Acta 674 (2010), 157–165.
47. [47] Yildiz, I., Applications of magnetic nanoparticles in biomedical separation and purification. Nanotechnol. Rev. 5 (2016), 331–340.
48. [48] Moraes Silva, S., Tavallaie, R., Sandiford, L., Tilley, R.D., Gooding, J.J., Gold coated magnetic nanoparticles: from preparation to surface modification for analytical and biomedical applications. Chem. Commun. 52 (2016), 7528–7540.
49. [49] Goon, I.Y., Lai, L.M.H., Lim, M., Munroe, P., Gooding, J.J., Amal, R., Fabrication and dispersion of gold-shell-protected magnetite nanoparticles: systematic control using polyethyleneimine. Chem. Mater. 21 (2009), 673–681.
50. [50] MoraesSilva, S., Tavallaie, R., TanzirulAlam, M., Chuah, K., Gooding, J.J., Comparison, A., Of differently synthesized gold-coated magnetic nanoparticles as ‘dispersible electrodes’. Electroanalysis 28 (2016), 431–438.
51. [51] Stephanie, I., Core@ shell nanomaterials: gold-coated magnetic oxide nanoparticles. J. Mater. Chem. 18 (2008), 2629–2635.
52. [52] Leung, K.C.-F., Xuan, S., Zhu, X., Wang, D., Chak, C.-P., Lee, S.-F., Ho, W.K.-W., Chung, B.C.-T., Gold and iron oxide hybrid nanocomposite materials. Chem. Soc. Rev. 41 (2012), 1911–1928.
53. [53] Chuah, K., Lai, L.M.H., Goon, I.Y., Parker, S.G., Amal, R., Justin Gooding, J., Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as ‘dispersible electrodes. Chem. Commun. 48 (2012), 3503–3505.
54. [54] Barman, J., Targeting cancer cells using aptamers: cell-SELEX approach and recent advancements. RSC Adv. 5 (2015), 11724–11732.
55. [55] Zhou, W., Jimmy Huang, P.-J., Ding, J., Liu, J., Aptamer-based biosensors for biomedical diagnostics. Analyst 139 (2014), 2627–2640.
56. [56] Jiang, Z., Le, N.D.B., Gupta, A., Rotello, V.M., Cell surface-based sensing with metallic nanoparticles. Chem. Soc. Rev. 44 (2015), 4264–4274.
57. [57] Costa, R.R., Mano, J.F., Polyelectrolyte multilayered assemblies in biomedical technologies. Chem. Soc. Rev. 43 (2014), 3453–3479.
58. [58] Barsan, M.M., Brett, C.M., Recent advances in layer-by-layer strategies for biosensors incorporating metal nanoparticles, TrAC. Trends Anal. Chem. 79 (2016), 286–296.
59. [59] Liu, X.Q., Picart, C., Layer-by-layer assemblies for cancer treatment and diagnosis. Adv. Mater. 28 (2016), 1295–1301.
60. [60] Wang, T., Liu, J., Gu, X., Li, D., Wang, J., Wang, E., Label-free electrochemical aptasensor constructed by layer-by-layer technology for sensitive and selective detection of cancer cells. Anal. Chim. Acta 882 (2015), 32–37.
61. [61] Sun, Y., Ren, Q., Liu, B., Qin, Y., Zhao, S., Enzyme-free and sensitive electrochemical determination of the FLT3 gene based on a dual signal amplified strategy: controlled nanomaterial multilayers and a target-catalyzed hairpin assembly. Biosens. Bioelectron. 78 (2016), 7–13.
62. [62] Bee, A., Massart, R., Neveu, S., Synthesis of very fine maghemite particles. J. Magn. Magn. Mater. 149 (1995), 6–9.
63. [63] Stöber, W., Fink, A., Bohn, E., Controlled growth of monodisperse silica spheres in the micron size range. J. Colloid Interface Sci. 26 (1968), 62–69.
64. [64] Xu, Y., Bai, H., Lu, G., Li, C., Shi, G., Flexible graphene films via the filtration of water-soluble noncovalent functionalized graphene sheets. J. Am. Chem. Soc. 130 (2008), 5856–5857.
65. [65] Li, D., Müller, M.B., Gilje, S., Kaner, R.B., Wallace, G.G., Processable aqueous dispersions of graphene nanosheets. Nat. Nanotechnol. 3 (2008), 101–105.
66. [66] Wang, D.-W., Gentle, I.R., Lu, G.Q.M., Enhanced electrochemical sensitivity of PtRh electrodes coated with nitrogen-doped graphene. Electrochem. Commun. 12 (2010), 1423–1427.
67. [67] Shangguan, D., Cao, Z., Meng, L., Mallikaratchy, P., Sefah, K., Wang, H., Li, Y., Tan, W., Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J. Proteome Res. 7 (2008), 2133–2139.
68. [68] Huang, Y.F., Shangguan, D., Liu, H., Phillips, J.A., Zhang, X., Chen, Y., Tan, W., Molecular assembly of an aptamer–drug conjugate for targeted drug delivery to tumor cells. Chembiochem 10 (2009), 862–868.
69. [69] Minasyan, S., Tavadyan, L., Antonyan, A., Davtyan, H., Parsadanyan, M., Vardevanyan, P., Differential pulse voltammetric studies of ethidium bromide binding to DNA. Bioelectrochemistry 68 (2006), 48–55.
70. [70] Bettazzi, F., Hamid-Asl, E., Esposito, C.L., Quintavalle, C., Formisano, N., Laschi, S., Catuogno, S., Iaboni, M., Marrazza, G., Mascini, M., Cerchia, L., De Franciscis, V., Condorelli, G., Palchetti, I., Electrochemical detection of miRNA-222 by use of a magnetic bead-based bioassay. Anal. Bioanal. Chem. 405 (2013), 1025–1034.
71. [71] Wang, Y., Li, Y., Tang, L., Lu, J., Li, J., Application of graphene-modified electrode for selective detection of dopamine. Electrochem. Commun. 11 (2009), 889–892.
72. [72] Wu, J.-F., Xu, M.-Q., Zhao, G.-C., Graphene-based modified electrode for the direct electron transfer of cytochrome c and biosensing. Electrochem. Commun. 12 (2010), 175–177.
73. [73] Wang, A.-J., Li, Y.-F., Li, Z.-H., Feng, J.-J., Sun, Y.-L., Chen, J.-R., Amperometric glucose sensor based on enhanced catalytic reduction of oxygen using glucose oxidase adsorbed onto core-shell Fe 3 O 4@ silica@ Au magnetic nanoparticles. Mater. Sci. Eng. C 32 (2012), 1640–1647.
74. [74] Chen, T., Shukoor, M.I., Chen, Y., Yuan, Q., Zhu, Z., Zhao, Z., Gulbakan, B., Tan, W., Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications. Nanoscale 3 (2011), 546–556.
75. [75] Oliveira, S.C.B., Nascimento, V.B., Electrochemical oxidation mechanism of ethidium bromide at a glassy carbon electrode. Electroanalysis 25 (2013), 2117–2123.
76. [76] Vardevanyan, P.O., Antonyan, A.P., Parsadanyan, M.A., Davtyan, H.G., Karapetyan, A.T., The binding of ethidium bromide with DNA: interaction with single- and double-stranded structures. Exp. Mol. Med. 35 (2003), 527–533.