메뉴 건너뛰기




Volumn 15, Issue 2, 2015, Pages e43-e46

Ofatumumab in refractory chronic lymphocytic leukemia: Experience through the french early access program

Author keywords

CD20; CLL; Ofatumumab; Relapsed refractory; Temporary use authorization

Indexed keywords

ALEMTUZUMAB; ANALGESIC AGENT; ANTIHISTAMINIC AGENT; CORTICOSTEROID; FLUDARABINE; OFATUMUMAB; RITUXIMAB; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

EID: 84921669944     PISSN: 21522650     EISSN: 21522669     Source Type: Journal    
DOI: 10.1016/j.clml.2014.07.013     Document Type: Article
Times cited : (9)

References (13)
  • 3
    • 68949129063 scopus 로고    scopus 로고
    • Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): Considerably higher levels of CDC are induced by OFA than by RTX
    • A.W. Pawluczkowycz, F.J. Beurskens, and P.V. Beum Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX J Immunol 183 2009 749 758
    • (2009) J Immunol , vol.183 , pp. 749-758
    • Pawluczkowycz, A.W.1    Beurskens, F.J.2    Beum, P.V.3
  • 4
    • 84871831846 scopus 로고    scopus 로고
    • Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy
    • L. Bologna, E. Gotti, and F. Da Roit Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy J Immunol 190 2013 231 239
    • (2013) J Immunol , vol.190 , pp. 231-239
    • Bologna, L.1    Gotti, E.2    Da Roit, F.3
  • 5
    • 84867164575 scopus 로고    scopus 로고
    • France's new framework for regulating off-label drug use
    • J. Emmerich, N. Dumarcet, and A. Lorence France's new framework for regulating off-label drug use N Engl J Med 367 2012 1279 1281
    • (2012) N Engl J Med , vol.367 , pp. 1279-1281
    • Emmerich, J.1    Dumarcet, N.2    Lorence, A.3
  • 6
    • 78650980278 scopus 로고    scopus 로고
    • The European Medicines Agency review of ofatumumab (Arzerra) for the treatment of chronic lymphocytic leukemia in patients refractory to fludarabine and alemtuzumab: Summary of the scientific assessment of the European Medicines Agency Committee for Medicinal Products for Human Use
    • I. Gravanis, J. Ersbøll, E. Skovlund, E. Abadie, M. Marty, and F. Pignatti The European Medicines Agency review of ofatumumab (Arzerra) for the treatment of chronic lymphocytic leukemia in patients refractory to fludarabine and alemtuzumab: summary of the scientific assessment of the European Medicines Agency Committee for Medicinal Products for Human Use Oncologist 15 2010 1335 1343
    • (2010) Oncologist , vol.15 , pp. 1335-1343
    • Gravanis, I.1    Ersbøll, J.2    Skovlund, E.3    Abadie, E.4    Marty, M.5    Pignatti, F.6
  • 7
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • M. Hallek, B.D. Cheson, and D. Catovsky Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines Blood 111 2008 5446 5456
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 8
    • 38949185742 scopus 로고    scopus 로고
    • Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: A phase 1-2 study
    • B. Coiffier, S. Lepretre, and L.M. Pedersen Safety and efficacy of ofatumumab, a fully human monoclonal anti-CD20 antibody, in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: a phase 1-2 study Blood 111 2008 1094 1100
    • (2008) Blood , vol.111 , pp. 1094-1100
    • Coiffier, B.1    Lepretre, S.2    Pedersen, L.M.3
  • 9
    • 77950502126 scopus 로고    scopus 로고
    • Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia
    • W.G. Wierda, T.J. Kipps, and J. Mayer Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia J Clin Oncol 28 2010 1749 1755
    • (2010) J Clin Oncol , vol.28 , pp. 1749-1755
    • Wierda, W.G.1    Kipps, T.J.2    Mayer, J.3
  • 10
    • 84976585919 scopus 로고    scopus 로고
    • Arzerra: summary of product characteristics. Available at: http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product-Information/human/001131/WC500093091.pdf.
    • Arzerra: Summary of Product Characteristics
  • 11
    • 81055148076 scopus 로고    scopus 로고
    • Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: Results from the phase 2 international study
    • W.G. Wierda, S. Padmanabhan, G.W. Chan, I.V. Gupta, S. Lisby, and A. Osterborg Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: results from the phase 2 international study Blood 118 2011 5126 5129
    • (2011) Blood , vol.118 , pp. 5126-5129
    • Wierda, W.G.1    Padmanabhan, S.2    Chan, G.W.3    Gupta, I.V.4    Lisby, S.5    Osterborg, A.6
  • 12
    • 84875241089 scopus 로고    scopus 로고
    • A case of long-term remission with ofatumumab maintenance therapy in multiply relapsed and rituximab-refractory chronic lymphocytic leukaemia with deletion 17p
    • K. Namberger, L. Weiss, B. Krause, T. Melchardt, and R. Greil A case of long-term remission with ofatumumab maintenance therapy in multiply relapsed and rituximab-refractory chronic lymphocytic leukaemia with deletion 17p Eur J Haematol 90 2013 349 350
    • (2013) Eur J Haematol , vol.90 , pp. 349-350
    • Namberger, K.1    Weiss, L.2    Krause, B.3    Melchardt, T.4    Greil, R.5
  • 13
    • 80054996610 scopus 로고    scopus 로고
    • Ofatumumab in advanced stage chronic lymphocytic leukaemia: Results of the UK named patient compassionate use programme
    • O. Chowdhury, A. Varghese, and J. Pattinson Ofatumumab in advanced stage chronic lymphocytic leukaemia: results of the UK named patient compassionate use programme Br J Haematol 155 2011 519 521
    • (2011) Br J Haematol , vol.155 , pp. 519-521
    • Chowdhury, O.1    Varghese, A.2    Pattinson, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.