Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity

Cell Stem Cell

Volumn 20, Issue 1, 2017, Pages 41-55

  Katsuda, Takeshi ^a   Kawamata, Masaki ^a,b   Hagiwara, Keitaro ^a   Takahashi, Ryou u ^a   Yamamoto, Yusuke ^a   Camargo, Fernando D ^b   Ochiya, Takahiro ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

bipotentiality; in vitro reprogramming; liver progenitor cell; liver repopulation; small molecule

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; A-83-01; AMIDE; MOLECULAR LIBRARY; PYRAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; THIOSEMICARBAZONE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; LIVER CELL; LIVER INJURY; LIVER REGENERATION; LIVER TISSUE; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; RAT; STEM CELL; ANIMAL; CELL CULTURE; CELL LINEAGE; CELL PROLIFERATION; CHIMERA; CYTOLOGY; DIPLOIDY; DRUG EFFECTS; EPITHELIUM CELL; INJURIES; LIVER; METABOLISM; MOLECULAR LIBRARY; MOUSE; NUCLEAR REPROGRAMMING; PATHOLOGY; PHARMACOLOGY; REGENERATION; REPRODUCIBILITY; TIME FACTOR;

AMIDES; ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELLS, CULTURED; CELLULAR REPROGRAMMING; CHIMERA; DIPLOIDY; EPITHELIAL CELLS; HEPATOCYTES; LIVER; LIVER REGENERATION; MICE; PYRAZOLES; PYRIDINES; PYRIMIDINES; RATS; REGENERATION; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES; STEM CELLS; THIOSEMICARBAZONES; TIME FACTORS;

EID: 85006263481     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.10.007     Document Type: Article

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