-
1
-
-
0031832805
-
Liver cell models in in vitro toxicology
-
Guillouzo A. Liver cell models in in vitro toxicology. Environ Health Perspect 1998;106(Suppl 2):511-532.
-
(1998)
Environ Health Perspect
, vol.106
, Issue.SUPPL. 2
, pp. 511-532
-
-
Guillouzo, A.1
-
2
-
-
0020822437
-
Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes
-
Clayton DF, Darnell JE Jr. Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol 1983;3:1552-1561.
-
(1983)
Mol Cell Biol
, vol.3
, pp. 1552-1561
-
-
Clayton, D.F.1
Darnell Jr., J.E.2
-
3
-
-
0029973363
-
Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1
-
Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C. Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1. J Biol Chem 1996;271:11484-11492.
-
(1996)
J Biol Chem
, vol.271
, pp. 11484-11492
-
-
Loyer, P.1
Cariou, S.2
Glaise, D.3
Bilodeau, M.4
Baffet, G.5
Guguen-Guillouzo, C.6
-
4
-
-
0035159826
-
Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations
-
Rescan C, Coutant A, Talarmin H, Theret N, Glaise D, Guguen-Guillouzo C, et al. Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations. Mol Biol Cell 2001;12:725-738.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 725-738
-
-
Rescan, C.1
Coutant, A.2
Talarmin, H.3
Theret, N.4
Glaise, D.5
Guguen-Guillouzo, C.6
-
5
-
-
0036287040
-
The EGF/ErbB receptor family and apoptosis
-
Danielsen AJ, Maihle NJ. The EGF/ErbB receptor family and apoptosis. Growth Factors 2002;20:1-15.
-
(2002)
Growth Factors
, vol.20
, pp. 1-15
-
-
Danielsen, A.J.1
Maihle, N.J.2
-
6
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
Pages G, Guerin S, Grall D, Bonino F, Smith A, Anjuere F, et al. Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 1999;286:1374-1377.
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pages, G.1
Guerin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
-
7
-
-
0242607637
-
An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development
-
Saba-El-Leil MK, Vella FD, Vernay B, Voisin L, Chen L, Labrecque N, et al. An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep 2003;4:964-968.
-
(2003)
EMBO Rep
, vol.4
, pp. 964-968
-
-
Saba-El-Leil, M.K.1
Vella, F.D.2
Vernay, B.3
Voisin, L.4
Chen, L.5
Labrecque, N.6
-
8
-
-
10744228332
-
Essential role for ERK2 mitogen-activated protein kinase in placental development
-
Hatano N, Mori Y, Oh-hora M, Kosugi A, Fujikawa T, Nakai N, et al. Essential role for ERK2 mitogen-activated protein kinase in placental development. Genes Cells 2003;8:847-856.
-
(2003)
Genes Cells
, vol.8
, pp. 847-856
-
-
Hatano, N.1
Mori, Y.2
Oh-hora, M.3
Kosugi, A.4
Fujikawa, T.5
Nakai, N.6
-
9
-
-
0242300107
-
Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation
-
Yao Y, Li W, Wu J, Germann UA, Su MS, Kuida K, et al. Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation. Proc Natl Acad Sci U S A 2003;100:12759-12764.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12759-12764
-
-
Yao, Y.1
Li, W.2
Wu, J.3
Germann, U.A.4
Su, M.S.5
Kuida, K.6
-
10
-
-
11144358069
-
MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo
-
Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, et al. MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation 2004;109:1938-1941.
-
(2004)
Circulation
, vol.109
, pp. 1938-1941
-
-
Lips, D.J.1
Bueno, O.F.2
Wilkins, B.J.3
Purcell, N.H.4
Kaiser, R.A.5
Lorenz, J.N.6
-
11
-
-
33744543239
-
ERK2 is required for efficient terminal differentiation of skeletal myoblasts
-
Li J, Johnson SE. ERK2 is required for efficient terminal differentiation of skeletal myoblasts. Biochem Biophys Res Commun 2006;345:1425-1433.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 1425-1433
-
-
Li, J.1
Johnson, S.E.2
-
12
-
-
37549016809
-
Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels
-
Lefloch R, Pouyssegur J, Lenormand P. Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels. Mol Cell Biol 2008;28:511-527.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 511-527
-
-
Lefloch, R.1
Pouyssegur, J.2
Lenormand, P.3
-
13
-
-
33845904217
-
ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially
-
Vantaggiato C, Formentini I, Bondanza A, Bonini C, Naldini L, Brambilla R. ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially. J Biol 2006;5:14.
-
(2006)
J Biol
, vol.5
, pp. 14
-
-
Vantaggiato, C.1
Formentini, I.2
Bondanza, A.3
Bonini, C.4
Naldini, L.5
Brambilla, R.6
-
14
-
-
0032795940
-
The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes
-
Talarmin H, Rescan C, Cariou S, Glaise D, Zanninelli G, Bilodeau M, et al. The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes. Mol Cell Biol 1999;19:6003-6011.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6003-6011
-
-
Talarmin, H.1
Rescan, C.2
Cariou, S.3
Glaise, D.4
Zanninelli, G.5
Bilodeau, M.6
-
15
-
-
34247358156
-
ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes
-
Fremin C, Ezan F, Boisselier P, Bessard A, Pages G, Pouyssegur J, et al. ERK2 but not ERK1 plays a key role in hepatocyte replication: An RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes. HEPATOLOGY 2007;45:1035-1045.
-
(2007)
HEPATOLOGY
, vol.45
, pp. 1035-1045
-
-
Fremin, C.1
Ezan, F.2
Boisselier, P.3
Bessard, A.4
Pages, G.5
Pouyssegur, J.6
-
17
-
-
0036830564
-
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival
-
Coutant A, Rescan C, Gilot D, Loyer P, Guguen-Guillouzo C, Baffet G. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival. HEPATOLOGY 2002;36:1079-1088.
-
(2002)
HEPATOLOGY
, vol.36
, pp. 1079-1088
-
-
Coutant, A.1
Rescan, C.2
Gilot, D.3
Loyer, P.4
Guguen-Guillouzo, C.5
Baffet, G.6
-
18
-
-
0032535711
-
Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice
-
Auer KL, Park JS, Seth P, Coffey RJ, Darlington G, Abo A, et al. Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice. Biochem J 1998;336: 551-560.
-
(1998)
Biochem J
, vol.336
, pp. 551-560
-
-
Auer, K.L.1
Park, J.S.2
Seth, P.3
Coffey, R.J.4
Darlington, G.5
Abo, A.6
-
19
-
-
0032521642
-
The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic
-
Tombes RM, Auer KL, Mikkelsen R, Valerie K, Wymann MP, Marshall CJ, McMahon M, et al. The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochem J 1998;330:1451-1460.
-
(1998)
Biochem J
, vol.330
, pp. 1451-1460
-
-
Tombes, R.M.1
Auer, K.L.2
Mikkelsen, R.3
Valerie, K.4
Wymann, M.P.5
Marshall, C.J.6
McMahon, M.7
-
20
-
-
0034490479
-
A role for both ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes
-
Park JS, Qiao L, Gilfor D, Yang MY, Hylemon PB, Benz C, et al. A role for both ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes. Mol Biol Cell 2000;11:2915-2932.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 2915-2932
-
-
Park, J.S.1
Qiao, L.2
Gilfor, D.3
Yang, M.Y.4
Hylemon, P.B.5
Benz, C.6
-
21
-
-
33745913027
-
An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway
-
Bessard A, Coutant A, Rescan C, Ezan F, Fremin C, Courselaud B, et al. An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway. HEPATOLOGY 2006;44:152-163.
-
(2006)
HEPATOLOGY
, vol.44
, pp. 152-163
-
-
Bessard, A.1
Coutant, A.2
Rescan, C.3
Ezan, F.4
Fremin, C.5
Courselaud, B.6
-
22
-
-
0026486878
-
Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
-
Traverse S, Gomez N, Paterson H, Marshall C, Cohen P. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem J 1992;288: 351-355.
-
(1992)
Biochem J
, vol.288
, pp. 351-355
-
-
Traverse, S.1
Gomez, N.2
Paterson, H.3
Marshall, C.4
Cohen, P.5
-
23
-
-
0030691207
-
Exposure of primary rat hepatocytes in long-term DMSO culture to selected transition metals induces hepatocyte proliferation and formation of duct-like structures
-
Cable EE, Isom HC. Exposure of primary rat hepatocytes in long-term DMSO culture to selected transition metals induces hepatocyte proliferation and formation of duct-like structures. HEPATOLOGY 1997;26:1444-1457.
-
(1997)
HEPATOLOGY
, vol.26
, pp. 1444-1457
-
-
Cable, E.E.1
Isom, H.C.2
-
24
-
-
0025909862
-
Effect of 2% dimethyl sulfoxide on the mitogenic properties of epidermal growth factor and hepatocyte growth factor in primary hepatocyte culture
-
Kost DP, Michalopoulos GK. Effect of 2% dimethyl sulfoxide on the mitogenic properties of epidermal growth factor and hepatocyte growth factor in primary hepatocyte culture. J Cell Physiol 1991;147:274-280.
-
(1991)
J Cell Physiol
, vol.147
, pp. 274-280
-
-
Kost, D.P.1
Michalopoulos, G.K.2
-
25
-
-
14244258690
-
TNFalpha-mediated extracellular matrix remodeling is required for multiple division cycles in rat hepatocytes
-
Serandour AL, Loyer P, Garnier D, Courselaud B, Theret N, Glaise D, et al. TNFalpha-mediated extracellular matrix remodeling is required for multiple division cycles in rat hepatocytes. HEPATOLOGY 2005;41:478-486.
-
(2005)
HEPATOLOGY
, vol.41
, pp. 478-486
-
-
Serandour, A.L.1
Loyer, P.2
Garnier, D.3
Courselaud, B.4
Theret, N.5
Glaise, D.6
-
26
-
-
34547101027
-
Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest
-
Mullany LK, Nelsen CJ, Hanse EA, GogginMM,Anttila CK, Peterson M, et al. Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest. J Biol Chem 2007;282:21244-21252.
-
(2007)
J Biol Chem
, vol.282
, pp. 21244-21252
-
-
Mullany, L.K.1
Nelsen, C.J.2
Hanse, E.A.3
GogginMM4
Anttila, C.K.5
Peterson, M.6
-
27
-
-
0036237044
-
The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers
-
Jaime M, Pujol MJ, Serratosa J, Pantoja C, Canela N, Casanovas O, et al. The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers. HEPATOLOGY 2002;35:1063-1071.
-
(2002)
HEPATOLOGY
, vol.35
, pp. 1063-1071
-
-
Jaime, M.1
Pujol, M.J.2
Serratosa, J.3
Pantoja, C.4
Canela, N.5
Casanovas, O.6
-
28
-
-
34547101027
-
Akt-mediated liver growth promotes inducation of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest
-
Mullany LK, Nelsen CJ, Hanse EA, Goggin MM, Anttila CK, Peterson M, et al. Akt-mediated liver growth promotes inducation of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest. J Biol Chem 2007;282:21244-21252.
-
(2007)
J Biol Chem
, vol.282
, pp. 21244-21252
-
-
Mullany, L.K.1
Nelsen, C.J.2
Hanse, E.A.3
Goggin, M.M.4
Anttila, C.K.5
Peterson, M.6
-
29
-
-
0037663743
-
Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth
-
Ilyin GP, Glaise D, Gilot D, Baffet G, Guguen-Guillouzo C. Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth. Am J Physiol Gastrointest Liver Physiol 2003;285:G115-G127.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Ilyin, G.P.1
Glaise, D.2
Gilot, D.3
Baffet, G.4
Guguen-Guillouzo, C.5
-
30
-
-
26644459229
-
The role of erk1 and erk2 in multiple stages of T cell development
-
Fischer AM, Katayama CD, Pages G, Pouyssegur J, Hedrick SM. The role of erk1 and erk2 in multiple stages of T cell development. Immunity 2005;23:431-443.
-
(2005)
Immunity
, vol.23
, pp. 431-443
-
-
Fischer, A.M.1
Katayama, C.D.2
Pages, G.3
Pouyssegur, J.4
Hedrick, S.M.5
-
31
-
-
1242272924
-
The MAP kinase pathway is required for entry into mitosis and cell survival
-
Liu X, Yan S, Zhou T, Terada Y, Erikson RL. The MAP kinase pathway is required for entry into mitosis and cell survival. Oncogene 2004;23:763-776.
-
(2004)
Oncogene
, vol.23
, pp. 763-776
-
-
Liu, X.1
Yan, S.2
Zhou, T.3
Terada, Y.4
Erikson, R.L.5
-
32
-
-
19944433322
-
The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis
-
Bost F, Aouadi M, Caron L, Even P, Belmonte N, Prot M, et al. The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes 2005;54:402-411.
-
(2005)
Diabetes
, vol.54
, pp. 402-411
-
-
Bost, F.1
Aouadi, M.2
Caron, L.3
Even, P.4
Belmonte, N.5
Prot, M.6
-
33
-
-
34347370458
-
-
Bessard A, Fremin C, Ezan F, Coutant A, Baffet G. MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells. J Cell Physiol 2007;212:526-536.
-
Bessard A, Fremin C, Ezan F, Coutant A, Baffet G. MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells. J Cell Physiol 2007;212:526-536.
-
-
-
-
34
-
-
33645072441
-
p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis
-
Bourcier C, Jacquel A, Hess J, Peyrottes I, Angel P, Hofman P, et al. p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis. Cancer Res 2006;66:2700-2707.
-
(2006)
Cancer Res
, vol.66
, pp. 2700-2707
-
-
Bourcier, C.1
Jacquel, A.2
Hess, J.3
Peyrottes, I.4
Angel, P.5
Hofman, P.6
-
35
-
-
27744564224
-
RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells
-
Zeng P, Wagoner HA, Pescovitz OH, Steinmetz R. RNA interference (RNAi) for extracellular signal-regulated kinase 1 (ERK1) alone is sufficient to suppress cell viability in ovarian cancer cells. Cancer Biol Ther 2005;4:961-967.
-
(2005)
Cancer Biol Ther
, vol.4
, pp. 961-967
-
-
Zeng, P.1
Wagoner, H.A.2
Pescovitz, O.H.3
Steinmetz, R.4
-
36
-
-
18444381728
-
Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory
-
Mazzucchelli C, Vantaggiato C, Ciamei A, Fasano S, Pakhotin P, Krezel W, et al. Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory. Neuron 2002;34:807-820.
-
(2002)
Neuron
, vol.34
, pp. 807-820
-
-
Mazzucchelli, C.1
Vantaggiato, C.2
Ciamei, A.3
Fasano, S.4
Pakhotin, P.5
Krezel, W.6
-
37
-
-
33846907736
-
Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G
-
Sanjo H, Hikida M, Aiba Y, Mori Y, Hatano N, Ogata M, et al. Extracellular signal-regulated protein kinase 2 is required for efficient generation of B cells bearing antigen-specific immunoglobulin G. Mol Cell Biol 2007; 27:1236-1246.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1236-1246
-
-
Sanjo, H.1
Hikida, M.2
Aiba, Y.3
Mori, Y.4
Hatano, N.5
Ogata, M.6
|