-
1
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363(8):711-23.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
2
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman P, Hauschild A, Robert C, Haanen J, Ascierto P, Larkin J, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011;364(26):2507-16.
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.1
Hauschild, A.2
Robert, C.3
Haanen, J.4
Ascierto, P.5
Larkin, J.6
-
3
-
-
84891648456
-
Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma
-
Ascierto P, Minor D, Ribas A, Lebbe C, O'Hagan A, Arya N, et al. Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma. J Clin Oncol. 2013;31(26):3205-11.
-
(2013)
J Clin Oncol
, vol.31
, Issue.26
, pp. 3205-3211
-
-
Ascierto, P.1
Minor, D.2
Ribas, A.3
Lebbe, C.4
O'Hagan, A.5
Arya, N.6
-
4
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
Flaherty KT, Infante JR, Daud A, Gonzalez R, Kefford RF, Sosman J, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med. 2012;367(18):1694-703.
-
(2012)
N Engl J Med
, vol.367
, Issue.18
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
Gonzalez, R.4
Kefford, R.F.5
Sosman, J.6
-
5
-
-
84908354848
-
Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
-
Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet. 2014;384(9948):1109-17.
-
(2014)
Lancet
, vol.384
, Issue.9948
, pp. 1109-1117
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
Hodi, F.S.4
Hamid, O.5
Kefford, R.6
-
6
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH, et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol. 2014;32(10):1020-30.
-
(2014)
J Clin Oncol
, vol.32
, Issue.10
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
7
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell G, Cox C, Stephens P, Edkins S, Clegg S, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417(6892):949-54.
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
8
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild A, Grob JJ, Demidov LV, Jouary T, Gutzmer R, Millward M, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet. 2012;380(9839):358-65.
-
(2012)
Lancet
, vol.380
, Issue.9839
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
Jouary, T.4
Gutzmer, R.5
Millward, M.6
-
9
-
-
84863116743
-
Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
-
Sosman JA, Kim KB, Schuchter L, Gonzalez R, Pavlick AC, Weber JS, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Eng J Med. 2012;366(8):707-14.
-
(2012)
N Eng J Med.
, vol.366
, Issue.8
, pp. 707-714
-
-
Sosman, J.A.1
Kim, K.B.2
Schuchter, L.3
Gonzalez, R.4
Pavlick, A.C.5
Weber, J.S.6
-
10
-
-
84891898344
-
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy
-
Shi H, Hugo W, Kong X, Hong A, Koya RC, Moriceau G, et al. Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy. Cancer Discov. 2014;4(1):80-93.
-
(2014)
Cancer Discov.
, vol.4
, Issue.1
, pp. 80-93
-
-
Shi, H.1
Hugo, W.2
Kong, X.3
Hong, A.4
Koya, R.C.5
Moriceau, G.6
-
11
-
-
84898738821
-
BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact
-
Rizos H, Menzies AM, Pupo GM, Carlino MS, Fung C, Hyman J, et al. BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact. Clin Cancer Res. 2014;20(7):1965-77.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.7
, pp. 1965-1977
-
-
Rizos, H.1
Menzies, A.M.2
Pupo, G.M.3
Carlino, M.S.4
Fung, C.5
Hyman, J.6
-
12
-
-
80051625929
-
Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling
-
Wagle N, Emery C, Berger MF, Davis MJ, Sawyer A, Pochanard P, et al. Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling. J Clin Oncol. 2011;29(22):3085-96.
-
(2011)
J Clin Oncol
, vol.29
, Issue.22
, pp. 3085-3096
-
-
Wagle, N.1
Emery, C.2
Berger, M.F.3
Davis, M.J.4
Sawyer, A.5
Pochanard, P.6
-
13
-
-
84862908097
-
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors
-
Su F, Viros A, Milagre C, Trunzer K, Bollag G, Spleiss O, et al. RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N Engl J Med. 2012;366(3):207-15.
-
(2012)
N Engl J Med
, vol.366
, Issue.3
, pp. 207-215
-
-
Su, F.1
Viros, A.2
Milagre, C.3
Trunzer, K.4
Bollag, G.5
Spleiss, O.6
-
14
-
-
84879754813
-
Dabrafenib: preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions
-
King AJ, Arnone MR, Bleam MR, Moss KG, Yang J, Fedorowicz KE, et al. Dabrafenib: preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions. PLoS ONE. 2013;8(7):e67583.
-
(2013)
PLoS ONE
, vol.8
, Issue.7
-
-
King, A.J.1
Arnone, M.R.2
Bleam, M.R.3
Moss, K.G.4
Yang, J.5
Fedorowicz, K.E.6
-
15
-
-
84863673204
-
Improved survival with MEK inhibition in BRAF-mutated melanoma
-
Flaherty KT, Robert C, Hersey P, Nathan P, Garbe C, Milhem M, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N Eng J Med. 2012;367(2):107-14.
-
(2012)
N Eng J Med.
, vol.367
, Issue.2
, pp. 107-114
-
-
Flaherty, K.T.1
Robert, C.2
Hersey, P.3
Nathan, P.4
Garbe, C.5
Milhem, M.6
-
16
-
-
84908257665
-
Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma
-
Long GV, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, et al. Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma. N Engl J Med. 2014;371(20):1877-88.
-
(2014)
N Engl J Med
, vol.371
, Issue.20
, pp. 1877-1888
-
-
Long, G.V.1
Stroyakovskiy, D.2
Gogas, H.3
Levchenko, E.4
Braud, F.5
Larkin, J.6
-
17
-
-
84938739283
-
Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
-
Long GV, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, et al. Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial. Lancet. 2015;386(9992):444-51.
-
(2015)
Lancet
, vol.386
, Issue.9992
, pp. 444-451
-
-
Long, G.V.1
Stroyakovskiy, D.2
Gogas, H.3
Levchenko, E.4
Braud, F.5
Larkin, J.6
-
18
-
-
84920394727
-
Improved overall survival in melanoma with combined dabrafenib and trametinib
-
Robert C, Karaszewska B, Schachter J, Rutkowski P, Mackiewicz A, Stroiakovski D, et al. Improved overall survival in melanoma with combined dabrafenib and trametinib. N Engl J Med. 2015;372(1):30-9.
-
(2015)
N Engl J Med
, vol.372
, Issue.1
, pp. 30-39
-
-
Robert, C.1
Karaszewska, B.2
Schachter, J.3
Rutkowski, P.4
Mackiewicz, A.5
Stroiakovski, D.6
-
19
-
-
84904916223
-
Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study
-
Ribas A, Gonzalez R, Pavlick A, Hamid O, Gajewski TF, Daud A, et al. Combination of vemurafenib and cobimetinib in patients with advanced BRAF(V600)-mutated melanoma: a phase 1b study. Lancet Oncol. 2014;15(9):954-65.
-
(2014)
Lancet Oncol.
, vol.15
, Issue.9
, pp. 954-965
-
-
Ribas, A.1
Gonzalez, R.2
Pavlick, A.3
Hamid, O.4
Gajewski, T.F.5
Daud, A.6
-
20
-
-
84948403152
-
Extended follow-up results of phase Ib study (BRIM7) of vemurafenib (VEM) with cobimetinib (COBI) in BRAF-mutant melanoma
-
Pavlick AC, Ribas A, Gonzalez R, Hamid O, Gajewski T, Daud A, Puzanov I, Hsu JJ, Choong NW, McArthur GA. Extended follow-up results of phase Ib study (BRIM7) of vemurafenib (VEM) with cobimetinib (COBI) in BRAF-mutant melanoma. J Clin Oncol. 2015;33(15):9020.
-
(2015)
J Clin Oncol
, vol.33
, Issue.15
, pp. 9020
-
-
Pavlick, A.C.1
Ribas, A.2
Gonzalez, R.3
Hamid, O.4
Gajewski, T.5
Daud, A.6
Puzanov, I.7
Hsu, J.J.8
Choong, N.W.9
McArthur, G.A.10
-
21
-
-
84908245075
-
Combined vemurafenib and cobimetinib in BRAF-mutated melanoma
-
Larkin J, Ascierto PA, Dréno B, Atkinson V, Liszkay G, Maio M, et al. Combined vemurafenib and cobimetinib in BRAF-mutated melanoma. N Engl J Med. 2014;371(20):1867-76.
-
(2014)
N Engl J Med
, vol.371
, Issue.20
, pp. 1867-1876
-
-
Larkin, J.1
Ascierto, P.A.2
Dréno, B.3
Atkinson, V.4
Liszkay, G.5
Maio, M.6
-
22
-
-
84938986183
-
Update of progression free survival (PFS) and correlative biomarker analysis from coBRIM: phase III study of cobimetinib (cobi) plus vemurafenib (vem) in advanced BRAF-mutated melanoma
-
Larkin JMG, Yan Y, Mcarthur GA, Ascierto PA, Liszkay G, Maio M, et al. Update of progression free survival (PFS) and correlative biomarker analysis from coBRIM: phase III study of cobimetinib (cobi) plus vemurafenib (vem) in advanced BRAF-mutated melanoma. J Clin Oncol. 2015;33:9006.
-
(2015)
J Clin Oncol
, vol.33
, pp. 9006
-
-
Larkin, J.M.G.1
Yan, Y.2
Mcarthur, G.A.3
Ascierto, P.A.4
Liszkay, G.5
Maio, M.6
-
23
-
-
84936821505
-
A phase Ib/II study of BRAF inhibitor (BRAFi) encorafenib (ENCO) plus MEK inhibitor (MEKi) binimetinib (BINI) in cutaneous melanoma patients naive to BRAFi treatment
-
Sullivan RJ, Weber JS, Patel SP, Dummer R, Miller WH, Cosgrove D, et al. A phase Ib/II study of BRAF inhibitor (BRAFi) encorafenib (ENCO) plus MEK inhibitor (MEKi) binimetinib (BINI) in cutaneous melanoma patients naive to BRAFi treatment. J Clin Oncol. 2015;33:9007.
-
(2015)
J Clin Oncol
, vol.33
, pp. 9007
-
-
Sullivan, R.J.1
Weber, J.S.2
Patel, S.P.3
Dummer, R.4
Miller, W.H.5
Cosgrove, D.6
-
24
-
-
84990226859
-
Results of NEMO: A phase III trial of binimetinib (BINI) vs dacarbazine (DTIC) in NRAS-mutant cutaneous melanoma
-
Dummer R, Schadendorf D, Ascierto PA, Arance Fernández AM, Dutriaux C, Maio M, Rutkowski P, et al. Results of NEMO: A phase III trial of binimetinib (BINI) vs dacarbazine (DTIC) in NRAS-mutant cutaneous melanoma. J Clin Oncol. 2016;34:9500.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9500
-
-
Dummer, R.1
Schadendorf, D.2
Ascierto, P.A.3
Arance Fernández, A.M.4
Dutriaux, C.5
Maio, M.6
Rutkowski, P.7
-
25
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 2013;369(2):134-44.
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
26
-
-
84938205998
-
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial
-
Ribas A, Puzanov I, Dummer R, Schadendorf D, Hamid O, Robert C, et al. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncol. 2015;16:908-18.
-
(2015)
Lancet Oncol
, vol.16
, pp. 908-918
-
-
Ribas, A.1
Puzanov, I.2
Dummer, R.3
Schadendorf, D.4
Hamid, O.5
Robert, C.6
-
27
-
-
84964341647
-
Association of pembrolizumab with tumor response and survival among patients with advanced melanoma
-
Ribas A, Hamid O, Daud A, Hodi FS, Wolchok JD, Kefford R, et al. Association of pembrolizumab with tumor response and survival among patients with advanced melanoma. JAMA. 2016;315(15):1600-9.
-
(2016)
JAMA
, vol.315
, Issue.15
, pp. 1600-1609
-
-
Ribas, A.1
Hamid, O.2
Daud, A.3
Hodi, F.S.4
Wolchok, J.D.5
Kefford, R.6
-
28
-
-
84995462969
-
Three-year overall survival for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001
-
Robert C, Ribas A, Hamid O, Daud A, Wolchok JD, Joshua AM, et al. Three-year overall survival for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001. J Clin Oncol. 2016;34:9503.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9503
-
-
Robert, C.1
Ribas, A.2
Hamid, O.3
Daud, A.4
Wolchok, J.D.5
Joshua, A.M.6
-
29
-
-
84929481481
-
Pembrolizumab vs ipilimumab in advanced melanoma
-
Robert C, Schachter J, Long GV, Arance A, Grob JJ, Mortier L, et al. Pembrolizumab vs ipilimumab in advanced melanoma. N Engl J Med. 2015;372(26):2521-32.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
Arance, A.4
Grob, J.J.5
Mortier, L.6
-
30
-
-
85011670254
-
Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival analysis of KEYNOTE-006
-
Schachter J, Ribas A, Long GV, Arance A, Grob JJ, Mortier L, et al. Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival analysis of KEYNOTE-006. J Clin Oncol. 2016;34:9504.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9504
-
-
Schachter, J.1
Ribas, A.2
Long, G.V.3
Arance, A.4
Grob, J.J.5
Mortier, L.6
-
31
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28:3167-75.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
32
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C, Long GV, Brady B, Dutriaux C, Maio M, Mortier L, et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med. 2015;372:320-30.
-
(2015)
N Engl J Med
, vol.372
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
Dutriaux, C.4
Maio, M.5
Mortier, L.6
-
33
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
-
Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2015;16:375-84.
-
(2015)
Lancet Oncol
, vol.16
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
Hodi, F.S.4
Gutzmer, R.5
Neyns, B.6
-
34
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev. 2009;229(1):12-26.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
35
-
-
2442585121
-
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
-
Chen L. Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nat Rev Immunol. 2004;4(5):336-47.
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.5
, pp. 336-347
-
-
Chen, L.1
-
36
-
-
84884561907
-
Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy
-
Nirschl CJ, Drake CG. Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res. 2013;19(18):4917-24.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.18
, pp. 4917-4924
-
-
Nirschl, C.J.1
Drake, C.G.2
-
37
-
-
33746336533
-
The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology
-
Sansom DM, Walker LS. The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology. Immunol Rev. 2006;212:131-48.
-
(2006)
Immunol Rev
, vol.212
, pp. 131-148
-
-
Sansom, D.M.1
Walker, L.S.2
-
38
-
-
53749094183
-
CTLA-4 control over Foxp3 + regulatory T cell function
-
Wing K, Onishi Y, Prieto-Martin P, Yamaguchi T, Miyara M, Fehervari Z, et al. CTLA-4 control over Foxp3 + regulatory T cell function. Science. 2008;322(5899):271-5.
-
(2008)
Science
, vol.322
, Issue.5899
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
-
39
-
-
84884287627
-
Treg and CTLA-4: two intertwining pathways to immune tolerance
-
Walker LSK. Treg and CTLA-4: two intertwining pathways to immune tolerance. J Autoimmun. 2013;45:49-57.
-
(2013)
J Autoimmun
, vol.45
, pp. 49-57
-
-
Walker, L.S.K.1
-
40
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco LM, Salinas VH, Brown KE, Vanguri VK, Freeman GJ, Kuchroo VK, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med. 2009;206(13):3015-29.
-
(2009)
J Exp Med
, vol.206
, Issue.13
, pp. 3015-3029
-
-
Francisco, L.M.1
Salinas, V.H.2
Brown, K.E.3
Vanguri, V.K.4
Freeman, G.J.5
Kuchroo, V.K.6
-
41
-
-
44349150012
-
Inhibitory B7-family molecules in the tumour microenvironment
-
Zou W, Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol. 2008;8(6):467-77.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.6
, pp. 467-477
-
-
Zou, W.1
Chen, L.2
-
42
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med. 2015;373:23-34.
-
(2015)
N Engl J Med
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, C.L.5
Lao, C.D.6
-
43
-
-
84982101639
-
Updated results from a phase III trial of nivolumab (NIVO) combined with ipilimumab (IPI) in treatment-naive patients (pts) with advanced melanoma (MEL) (CheckMate 067)
-
Wolchok JD, Chiarion-Sileni V, Gonzalez R, Rutkowski P, Grob JJ, Cowey CL, et al. Updated results from a phase III trial of nivolumab (NIVO) combined with ipilimumab (IPI) in treatment-naive patients (pts) with advanced melanoma (MEL) (CheckMate 067). J Clin Oncol. 2016;34:9505.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9505
-
-
Wolchok, J.D.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Rutkowski, P.4
Grob, J.J.5
Cowey, C.L.6
-
44
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med. 2015;372:2006-17.
-
(2015)
N Engl J Med
, vol.372
, pp. 2006-2017
-
-
Postow, M.A.1
Chesney, J.2
Pavlick, A.C.3
Robert, C.4
Grossmann, K.5
McDermott, D.6
-
45
-
-
84945968491
-
Nivolumab plus ipilimumab in the treatment of advanced melanoma
-
Tsai KK, Daud AI. Nivolumab plus ipilimumab in the treatment of advanced melanoma. J Hematol Oncol. 2015;31(8):123.
-
(2015)
J Hematol Oncol.
, vol.31
, Issue.8
, pp. 123
-
-
Tsai, K.K.1
Daud, A.I.2
-
46
-
-
84990177918
-
Pembrolizumab (pembro) plus ipilimumab (ipi) for advanced melanoma: results of the KEYNOTE-029 expansion cohort
-
Long GV, Atkinson V, Cebon JS, Jameson MB, Fitzharris BM, McNeil CM, et al. Pembrolizumab (pembro) plus ipilimumab (ipi) for advanced melanoma: results of the KEYNOTE-029 expansion cohort. J Clin Oncol. 2016;34:9506.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9506
-
-
Long, G.V.1
Atkinson, V.2
Cebon, J.S.3
Jameson, M.B.4
Fitzharris, B.M.5
McNeil, C.M.6
-
47
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
-
Liu BL, Robinson M, Han ZQ, Branston RH, English C, Reay P, et al. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Gene Ther. 2003;10:292-303.
-
(2003)
Gene Ther
, vol.10
, pp. 292-303
-
-
Liu, B.L.1
Robinson, M.2
Han, Z.Q.3
Branston, R.H.4
English, C.5
Reay, P.6
-
48
-
-
0031951655
-
Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse TAP
-
Tomazin R, van Schoot NE, Goldsmith K, Jugovic P, Sempe P, Fruh K, et al. Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse TAP. J Virol. 1998;72:2560-3.
-
(1998)
J Virol
, vol.72
, pp. 2560-2563
-
-
Tomazin, R.1
Schoot, N.E.2
Goldsmith, K.3
Jugovic, P.4
Sempe, P.5
Fruh, K.6
-
49
-
-
0029034237
-
Herpes simplex virus turns off the TAP to evade host immunity
-
Hill A, Jugovic P, York I, Russ G, Bennink J, Yewdell J, et al. Herpes simplex virus turns off the TAP to evade host immunity. Nature. 1995;375:411-5.
-
(1995)
Nature
, vol.375
, pp. 411-415
-
-
Hill, A.1
Jugovic, P.2
York, I.3
Russ, G.4
Bennink, J.5
Yewdell, J.6
-
50
-
-
84977111376
-
Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma
-
Kaufman HL, Ruby CE, Hughes T, Slingluff CL Jr. Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma. J Immunother Cancer. 2014;2:11.
-
(2014)
J Immunother Cancer
, vol.2
, pp. 11
-
-
Kaufman, H.L.1
Ruby, C.E.2
Hughes, T.3
Slingluff, C.L.4
-
51
-
-
33845336115
-
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
-
Hu JCC, Coffin RS, Davis CJ. A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res. 2006;12:6737-47.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6737-6747
-
-
Hu, J.C.C.1
Coffin, R.S.2
Davis, C.J.3
-
52
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
-
Senzer NN, Kaufman HL, Amatruda T, Nemunaitis M, Reid T, Daniels G, et al. Phase II clinical trial of a granulocyte-macrophage colony stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol. 2009;27:5763-71.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5763-5771
-
-
Senzer, N.N.1
Kaufman, H.L.2
Amatruda, T.3
Nemunaitis, M.4
Reid, T.5
Daniels, G.6
-
53
-
-
84933586864
-
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma
-
Andtbacka RHI, Kaufman HL, Collichio F, Amatruda T, Senzer N, Chesney J, et al. Talimogene laherparepvec improves durable response rate in patients with advanced melanoma. J Clin Oncol. 2015;33:2780-8.
-
(2015)
J Clin Oncol
, vol.33
, pp. 2780-2788
-
-
Andtbacka, R.H.I.1
Kaufman, H.L.2
Collichio, F.3
Amatruda, T.4
Senzer, N.5
Chesney, J.6
-
54
-
-
84997077977
-
Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study
-
Kaufman HL, Amatruda T, Reid T, Gonzalez R, Glaspy J, Whitman E, et al. Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study. J Immunother Cancer. 2016;15(4):12.
-
(2016)
J Immunother Cancer.
, vol.15
, Issue.4
, pp. 12
-
-
Kaufman, H.L.1
Amatruda, T.2
Reid, T.3
Gonzalez, R.4
Glaspy, J.5
Whitman, E.6
-
55
-
-
77954373338
-
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function
-
Boni A, Cogdill AP, Dang P, Udayakumar D, Njauw CN, Sloss CM, et al. Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res. 2010;70(13):5213-9.
-
(2010)
Cancer Res
, vol.70
, Issue.13
, pp. 5213-5219
-
-
Boni, A.1
Cogdill, A.P.2
Dang, P.3
Udayakumar, D.4
Njauw, C.N.5
Sloss, C.M.6
-
56
-
-
84885816614
-
Vemurafenib enhances MHC induction in BRAF homozygous melanoma cells
-
Sapkota B, Hill CE, Pollack BP. Vemurafenib enhances MHC induction in BRAF homozygous melanoma cells. Oncoimmunology. 2013;2:22890.
-
(2013)
Oncoimmunology.
, vol.2
, pp. 22890
-
-
Sapkota, B.1
Hill, C.E.2
Pollack, B.P.3
-
57
-
-
84874872137
-
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
-
Frederick DT, Piris A, Cogdill AP, Cooper ZA, Lezcano C, Ferrone CR, et al. BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma. Clin Cancer Res. 2013;19(5):1225-31.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.5
, pp. 1225-1231
-
-
Frederick, D.T.1
Piris, A.2
Cogdill, A.P.3
Cooper, Z.A.4
Lezcano, C.5
Ferrone, C.R.6
-
58
-
-
84883008576
-
BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer
-
Donia M, Fagone P, Nicoletti F, Andersen RS, Høgdall E, Straten PT, et al. BRAF inhibition improves tumor recognition by the immune system: Potential implications for combinatorial therapies against melanoma involving adoptive T-cell transfer. Oncoimmunology. 2012;1(9):1476-83.
-
(2012)
Oncoimmunology.
, vol.1
, Issue.9
, pp. 1476-1483
-
-
Donia, M.1
Fagone, P.2
Nicoletti, F.3
Andersen, R.S.4
Høgdall, E.5
Straten, P.T.6
-
59
-
-
84863393623
-
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma
-
Wilmott JS, Long GV, Howle JR, Haydu LE, Sharma RN, Thompson JF, et al. Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma. Clin Cancer Res. 2012;18(5):1386-94.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.5
, pp. 1386-1394
-
-
Wilmott, J.S.1
Long, G.V.2
Howle, J.R.3
Haydu, L.E.4
Sharma, R.N.5
Thompson, J.F.6
-
60
-
-
84879786038
-
Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression
-
Long GV, Wilmott JS, Haydu LE, Tembe V, Sharma R, Rizos H, Thompson JF, et al. Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression. Pigment Cell Melanoma Res. 2013;26(4):499-508.
-
(2013)
Pigment Cell Melanoma Res.
, vol.26
, Issue.4
, pp. 499-508
-
-
Long, G.V.1
Wilmott, J.S.2
Haydu, L.E.3
Tembe, V.4
Sharma, R.5
Rizos, H.6
Thompson, J.F.7
-
61
-
-
84865112760
-
BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy
-
Koya RC, Mok S, Otte N, Blacketor KJ, Comin-Anduix B, Tumeh PC, Minasyan A, et al. BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy. Cancer Res. 2012;72(16):3928-37.
-
(2012)
Cancer Res
, vol.72
, Issue.16
, pp. 3928-3937
-
-
Koya, R.C.1
Mok, S.2
Otte, N.3
Blacketor, K.J.4
Comin-Anduix, B.5
Tumeh, P.C.6
Minasyan, A.7
-
62
-
-
78650391890
-
The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations
-
Comin-Anduix B, Chodon T, Sazegar H, Matsunaga D, Mock S, Jalil J, et al. The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations. Clin Cancer Res. 2010;16(24):6040-8.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.24
, pp. 6040-6048
-
-
Comin-Anduix, B.1
Chodon, T.2
Sazegar, H.3
Matsunaga, D.4
Mock, S.5
Jalil, J.6
-
63
-
-
33750598863
-
Role of the mitogen-activated protein kinase signaling pathway in the regulation of human melanocytic antigen expression
-
Kono M, Dunn IS, Durda PJ, Butera D, Rose LB, Haggerty TJ, et al. Role of the mitogen-activated protein kinase signaling pathway in the regulation of human melanocytic antigen expression. Mol Cancer Res. 2006;4(10):779-92.
-
(2006)
Mol Cancer Res
, vol.4
, Issue.10
, pp. 779-792
-
-
Kono, M.1
Dunn, I.S.2
Durda, P.J.3
Butera, D.4
Rose, L.B.5
Haggerty, T.J.6
-
64
-
-
84904286464
-
MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells
-
Vella LJ, Pasam A, Dimopoulos N, Andrews M, Knights A, Puaux AL, et al. MEK inhibition, alone or in combination with BRAF inhibition, affects multiple functions of isolated normal human lymphocytes and dendritic cells. Cancer Immunol Res. 2014;2(4):351-60.
-
(2014)
Cancer Immunol Res.
, vol.2
, Issue.4
, pp. 351-360
-
-
Vella, L.J.1
Pasam, A.2
Dimopoulos, N.3
Andrews, M.4
Knights, A.5
Puaux, A.L.6
-
65
-
-
84875785905
-
Hepatotoxicity with combination of vemurafenib and ipilimumab
-
Ribas A, Hodi FS, Callahan M, Konto C, Wolchok J. Hepatotoxicity with combination of vemurafenib and ipilimumab. N Engl J Med. 2013;368:1365-6.
-
(2013)
N Engl J Med
, vol.368
, pp. 1365-1366
-
-
Ribas, A.1
Hodi, F.S.2
Callahan, M.3
Konto, C.4
Wolchok, J.5
-
66
-
-
84912135461
-
Phase 1 study of the BRAF inhibitor dabrafenib (D) with or without the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM)
-
Puzanov I, Callahan MK, Linette GP, Patel SP, Luke JL, Sosman JA, et al. Phase 1 study of the BRAF inhibitor dabrafenib (D) with or without the MEK inhibitor trametinib (T) in combination with ipilimumab (Ipi) for V600E/K mutation-positive unresectable or metastatic melanoma (MM). J Clin Oncol. 2014;32(5):2511.
-
(2014)
J Clin Oncol
, vol.32
, Issue.5
, pp. 2511
-
-
Puzanov, I.1
Callahan, M.K.2
Linette, G.P.3
Patel, S.P.4
Luke, J.L.5
Sosman, J.A.6
-
67
-
-
84936821507
-
Phase I study combining anti-PD-L1 (MEDI4736) with BRAF (dabrafenib) and/or MEK (trametinib) inhibitors in advanced melanoma
-
Ribas A, Butler M, Lutzky J, Lawrence DP, Robert C, Miller W, et al. Phase I study combining anti-PD-L1 (MEDI4736) with BRAF (dabrafenib) and/or MEK (trametinib) inhibitors in advanced melanoma. J Clin Oncol. 2015;33:3003.
-
(2015)
J Clin Oncol
, vol.33
, pp. 3003
-
-
Ribas, A.1
Butler, M.2
Lutzky, J.3
Lawrence, D.P.4
Robert, C.5
Miller, W.6
-
68
-
-
84979599378
-
Talimogene laherparepvec in combination with ipilimumab in previously untreated, unresectable stage IIIB-IV melanoma
-
Puzanov I, Milhem MM, Minor D, Hamid O, Li A, Chen L, et al. Talimogene laherparepvec in combination with ipilimumab in previously untreated, unresectable stage IIIB-IV melanoma. J Clin Oncol. 2016;. doi: 10.1200/JCO.2016.67.1529.
-
(2016)
J Clin Oncol
-
-
Puzanov, I.1
Milhem, M.M.2
Minor, D.3
Hamid, O.4
Li, A.5
Chen, L.6
-
69
-
-
0028927442
-
Nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts
-
Weterman MA, Ajubi N, van Dinter IM, Degen WG, van Muijen GN, Ruitter DJ, et al. Nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts. Int J Cancer. 1995;60(1):73-81.
-
(1995)
Int J Cancer
, vol.60
, Issue.1
, pp. 73-81
-
-
Weterman, M.A.1
Ajubi, N.2
Dinter, I.M.3
Degen, W.G.4
Muijen, G.N.5
Ruitter, D.J.6
-
70
-
-
33644747384
-
CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma
-
Tse KF, Jeffers M, Pollack VA, McCabe DA, Shadish ML, Khramtsov NV, et al. CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma. Clin Cancer Res. 2006;12(4):1373-82.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.4
, pp. 1373-1382
-
-
Tse, K.F.1
Jeffers, M.2
Pollack, V.A.3
McCabe, D.A.4
Shadish, M.L.5
Khramtsov, N.V.6
-
71
-
-
10744222473
-
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
-
Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF, et al. Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol. 2003;21(7):778-84.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.7
, pp. 778-784
-
-
Doronina, S.O.1
Toki, B.E.2
Torgov, M.Y.3
Mendelsohn, B.A.4
Cerveny, C.G.5
Chace, D.F.6
-
72
-
-
55249097877
-
Novel peptide linkers for highly potent antibodyauristatin conjugate
-
Doronina SO, Bovee TD, Meyer DW, Miyamoto JB, Anderson ME, Morris-Tilden CA, et al. Novel peptide linkers for highly potent antibodyauristatin conjugate. Bioconjug Chem. 2008;19(10):1960-3.
-
(2008)
Bioconjug Chem.
, vol.19
, Issue.10
, pp. 1960-1963
-
-
Doronina, S.O.1
Bovee, T.D.2
Meyer, D.W.3
Miyamoto, J.B.4
Anderson, M.E.5
Morris-Tilden, C.A.6
-
73
-
-
33745684533
-
Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment
-
McDonagh CF, Turcott E, Westendorf L, Webster JB, Alley SC, Kim K, et al. Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment. Protein Eng Des Sel. 2006;19(7):299-307.
-
(2006)
Protein Eng Des Sel
, vol.19
, Issue.7
, pp. 299-307
-
-
McDonagh, C.F.1
Turcott, E.2
Westendorf, L.3
Webster, J.B.4
Alley, S.C.5
Kim, K.6
-
74
-
-
34250613133
-
Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB
-
Pollack VA, Alvarez E, Tse KF, Torgov MY, Xie S, Shenoy SG, et al. Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB. Cancer Chemother Pharmacol. 2007;60(3):423-35.
-
(2007)
Cancer Chemother Pharmacol
, vol.60
, Issue.3
, pp. 423-435
-
-
Pollack, V.A.1
Alvarez, E.2
Tse, K.F.3
Torgov, M.Y.4
Xie, S.5
Shenoy, S.G.6
-
75
-
-
84911933928
-
Phase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma
-
Ott PA, Hamid O, Pavlick AC, Kluger H, Kim KB, Boasberg PD, et al. Phase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma. J Clin Oncol. 2014;32(32):3659-66.
-
(2014)
J Clin Oncol
, vol.32
, Issue.32
, pp. 3659-3666
-
-
Ott, P.A.1
Hamid, O.2
Pavlick, A.C.3
Kluger, H.4
Kim, K.B.5
Boasberg, P.D.6
-
76
-
-
56849112041
-
Chemoablation of metastatic melanoma using intralesional rose bengal
-
Thompson JF, Hersey P, Wachter E. Chemoablation of metastatic melanoma using intralesional rose bengal. Melanoma Res. 2008;18:405-11.
-
(2008)
Melanoma Res
, vol.18
, pp. 405-411
-
-
Thompson, J.F.1
Hersey, P.2
Wachter, E.3
-
77
-
-
0346944007
-
A new liver function test. The elimination of rose bengal when injected into the circulation of human subjects
-
Delprat GD, Epstein NN, Kerr WJ. A new liver function test. The elimination of rose bengal when injected into the circulation of human subjects. Arch Intern Med. 1924;34:533-41.
-
(1924)
Arch Intern Med
, vol.34
, pp. 533-541
-
-
Delprat, G.D.1
Epstein, N.N.2
Kerr, W.J.3
-
79
-
-
0036059488
-
Imaging photosensitizer distribution and pharmacology using multiphoton microscopy
-
In: Farkas DL, Leif RC, editors. Bellingham: SPIE
-
Wachter E, Dees C, Harkins J, Fisher W, Scott T. Imaging photosensitizer distribution and pharmacology using multiphoton microscopy. In: Farkas DL, Leif RC, editors. Proceedings of SPIE, optical diagnostics of living cells V. Bellingham: SPIE; 2002. p. 112-8.
-
(2002)
Proceedings of SPIE, optical diagnostics of living cells V.
, pp. 112-118
-
-
Wachter, E.1
Dees, C.2
Harkins, J.3
Fisher, W.4
Scott, T.5
-
80
-
-
84880437254
-
Intralesional injection of rose bengal induces a systemic tumor-specific immune response in murine models of melanoma and breast cancer
-
Toomey P, Kodumudi K, Weber A, Kuhn L, Moore E, Sarnaik AA, et al. Intralesional injection of rose bengal induces a systemic tumor-specific immune response in murine models of melanoma and breast cancer. PLoS ONE. 2013;8:e68561.
-
(2013)
PLoS ONE
, vol.8
-
-
Toomey, P.1
Kodumudi, K.2
Weber, A.3
Kuhn, L.4
Moore, E.5
Sarnaik, A.A.6
-
81
-
-
84910608166
-
Assessment of immune and clinical efficacy after intralesional PV-10 in injected and uninjected metastatic melanoma lesions
-
Sarnaik A, Crago G, Liu H, Kodumudi K, Weber A, McCardle T, et al. Assessment of immune and clinical efficacy after intralesional PV-10 in injected and uninjected metastatic melanoma lesions. J Clin Oncol. 2014;32(Suppl 5s):9028.
-
(2014)
J Clin Oncol
, vol.32
, pp. 9028
-
-
Sarnaik, A.1
Crago, G.2
Liu, H.3
Kodumudi, K.4
Weber, A.5
McCardle, T.6
-
82
-
-
84930480545
-
Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma
-
Thompson JF, Agarwala SS, Smithers BM, Ross MI, Scoggins CR, Coventry BJ, et al. Phase 2 Study of Intralesional PV-10 in Refractory Metastatic Melanoma. Ann Surg Oncol. 2015;22:2135-42.
-
(2015)
Ann Surg Oncol
, vol.22
, pp. 2135-2142
-
-
Thompson, J.F.1
Agarwala, S.S.2
Smithers, B.M.3
Ross, M.I.4
Scoggins, C.R.5
Coventry, B.J.6
-
83
-
-
85006214983
-
Preliminary results from phase II study of combination treatment with HF10, a replication-competent HSV-1 oncolytic virus, and ipilimumab in patients with stage IIIb, IIIc, or IV unresectable or metastatic melanoma
-
Andtbacka RHI, Ross MI, Agarwala SS, Taylor MH, Vetto JT, Neves RI, et al. Preliminary results from phase II study of combination treatment with HF10, a replication-competent HSV-1 oncolytic virus, and ipilimumab in patients with stage IIIb, IIIc, or IV unresectable or metastatic melanoma. J Clin Oncol. 2016;34:9543.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9543
-
-
Andtbacka, R.H.I.1
Ross, M.I.2
Agarwala, S.S.3
Taylor, M.H.4
Vetto, J.T.5
Neves, R.I.6
-
84
-
-
85006184378
-
Phase I study of vemurafenib and heat shock protein 90 (HSP90) inhibitor XL888 in metastatic BRAF V600 mutant melanoma
-
Eroglu Z, Gibney GT, Weber JS, Kudchadkar RR, Khushalani NI, Markowitz J, et al. Phase I study of vemurafenib and heat shock protein 90 (HSP90) inhibitor XL888 in metastatic BRAF V600 mutant melanoma. J Clin Oncol. 2016;34:9544.
-
(2016)
J Clin Oncol
, vol.34
, pp. 9544
-
-
Eroglu, Z.1
Gibney, G.T.2
Weber, J.S.3
Kudchadkar, R.R.4
Khushalani, N.I.5
Markowitz, J.6
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