메뉴 건너뛰기




Volumn 8, Issue 1, 2015, Pages

Nivolumab plus ipilimumab in the treatment of advanced melanoma

Author keywords

CTLA 4; Immunotherapy; Ipilimumab; Melanoma; Nivolumab; PD 1

Indexed keywords

DACARBAZINE; IPILIMUMAB; NIVOLUMAB; PROGRAMMED DEATH 1 LIGAND 1; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

EID: 84945968491     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-015-0219-0     Document Type: Review
Times cited : (46)

References (16)
  • 1
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med. 1995;182:459-65.
    • (1995) J Exp Med. , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 2
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel MF, Allison JP. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J Exp Med. 1996;183:2533-40.
    • (1996) J Exp Med. , vol.183 , pp. 2533-2540
    • Krummel, M.F.1    Allison, J.P.2
  • 3
    • 0026700235 scopus 로고
    • Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death
    • Ishida Y, Agata Y, Shibahara K, Honjo T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. EMBO J. 1992;11:3887-95.
    • (1992) EMBO J. , vol.11 , pp. 3887-3895
    • Ishida, Y.1    Agata, Y.2    Shibahara, K.3    Honjo, T.4
  • 4
    • 84887862839 scopus 로고    scopus 로고
    • A rheostat for immune responses: The unique properties of PD-1 and their advantages for clinical application
    • Okazaki T, Chikuma S, Iwai Y, Fagarasan S, Honjo T. A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application. Nat Immunol. 2013;14:1212-8.
    • (2013) Nat Immunol. , vol.14 , pp. 1212-1218
    • Okazaki, T.1    Chikuma, S.2    Iwai, Y.3    Fagarasan, S.4    Honjo, T.5
  • 5
    • 77749279776 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
    • Curran MA, Montalvo W, Yagita H, Allison JP. PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci. 2010;107:4275-80.
    • (2010) Proc Natl Acad Sci. , vol.107 , pp. 4275-4280
    • Curran, M.A.1    Montalvo, W.2    Yagita, H.3    Allison, J.P.4
  • 6
    • 84880322360 scopus 로고    scopus 로고
    • Antitumor activity of concurrent blockade of immune checkpoint molecules CTLA-4 and PD-1 in preclinical models
    • (suppl;abstr 3061)
    • Selby M, Engelhardt H, Lu L-S, Quigley M, Wang C, Chen B, et al. Antitumor activity of concurrent blockade of immune checkpoint molecules CTLA-4 and PD-1 in preclinical models. J Clin Oncol 31, 2013(suppl;abstr 3061).
    • (2013) J Clin Oncol , vol.31
    • Selby, M.1    Engelhardt, H.2    Lu, L.-S.3    Quigley, M.4    Wang, C.5    Chen, B.6
  • 7
    • 84921456279 scopus 로고    scopus 로고
    • Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo
    • Das R, Verma R, Sznol M, Boddupalli CS, Gettinger SN, Kluger H, et al. Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo. J Immunol. 2015;194:950-9.
    • (2015) J Immunol. , vol.194 , pp. 950-959
    • Das, R.1    Verma, R.2    Sznol, M.3    Boddupalli, C.S.4    Gettinger, S.N.5    Kluger, H.6
  • 12
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med. 2011;364:2517-26.
    • (2011) N Engl J Med. , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.4    Weber, J.5    Garbe, C.6
  • 14
    • 84925622262 scopus 로고    scopus 로고
    • A phase 3 randomized, open-label study of nivolumab (anti-PD-1; BMS-936558; ONO-4538) versus investigator's choicechemotherapy (ICC) in patients with advanced melanoma with prior anti-CTLA-4 therapy
    • Presented at the, Madrid, September 26-30, 2014. abstract
    • Weber JS, Minor D, D'Angelo SP, Hodi FS, Gutzmer R, Bart N, et al. A phase 3 randomized, open-label study of nivolumab (anti-PD-1; BMS-936558; ONO-4538) versus investigator's choicechemotherapy (ICC) in patients with advanced melanoma with prior anti-CTLA-4 therapy, Presented at the European Society for Medical Oncology 2014 Congress, Madrid, September 26-30, 2014. 2014. abstract.
    • (2014) European Society for Medical Oncology 2014 Congress
    • Weber, J.S.1    Minor, D.2    D'Angelo, S.P.3    Hodi, F.S.4    Gutzmer, R.5    Bart, N.6
  • 15
    • 84907996097 scopus 로고    scopus 로고
    • Strategies for modern biomarker and drug development in oncology
    • Smith AD, Roda D, Yap TA. Strategies for modern biomarker and drug development in oncology. J Hematol Oncol. 2014;7:70.
    • (2014) J Hematol Oncol. , vol.7 , pp. 70
    • Smith, A.D.1    Roda, D.2    Yap, T.A.3
  • 16
    • 84907498833 scopus 로고    scopus 로고
    • Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL)
    • Sznol M, Kluger HM, Callahan MK, Postow MA, Gordon RA, Segal NH, et al. Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL). J Clin Oncol. 2014;32(5s).
    • (2014) J Clin Oncol. , vol.32 , Issue.5 S
    • Sznol, M.1    Kluger, H.M.2    Callahan, M.K.3    Postow, M.A.4    Gordon, R.A.5    Segal, N.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.