Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia

Human Molecular Genetics

Volumn 23, Issue 25, 2014, Pages 6838-6847

  Hayashi, Genki ^a   Shen, Yan ^a   Pedersen, Theresa L ^b   Newman, John W ^a,b   Pook, Mark ^c   Cortopassi, Gino ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11-HYDROXY-5,8,12,14-EICOSATETRAENOIC ACID; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FRATAXIN; HYDROXYICOSATETRAENOIC ACID; IRON BINDING PROTEIN; MEMBRANE PROTEIN; OXYLIPIN; PROSTAGLANDIN; PTGS1 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; THROMBOXANE B2; TRANSCRIPTION FACTOR AP 1;

ANIMAL; B LYMPHOCYTE; C57BL MOUSE; CELL LINE; CEREBELLUM; FRIEDREICH ATAXIA; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; METABOLISM; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; B-LYMPHOCYTES; CELL LINE; CEREBELLUM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FRIEDREICH ATAXIA; GENE EXPRESSION REGULATION; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; INFLAMMATION; IRON-BINDING PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXYLIPINS; PROSTAGLANDINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THROMBOXANE B2; TRANSCRIPTION FACTOR AP-1;

EID: 85005896319     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu407     Document Type: Article

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