Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction

Journal of Hepatology

Volumn 65, Issue 6, 2016, Pages 1198-1208

  van Zutphen, Tim ^a   Ciapaite, Jolita ^a   Bloks, Vincent W ^a   Ackereley, Cameron ^b   Gerding, Albert ^a   Jurdzinski, Angelika ^a   de Moraes, Roberta Allgayer ^a   Zhang, Ling ^c   Wolters, Justina C ^a,d   Bischoff, Rainer ^a,d   Wanders, Ronald J ^e   Houten, Sander M ^e   Bronte Tinkew, Dana ^b   Shatseva, Tatiana ^b   Lewis, Gary F ^f   Groen, Albert K ^a   Reijngoud, Dirk Jan ^a   Bakker, Barbara M ^a   Jonker, Johan W ^a   Kim, Peter K ^b,f   Bandsma, Robert H J ^a,b,c   more..

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

Hepatic steatosis; Kwashiorkor; Malnutrition; Marasmus; Metabolism; Mitochondria; Peroxisomes; Targeted quantitative proteomics

Indexed keywords

ADENOSINE TRIPHOSPHATE; FENOFIBRATE; MITOCHONDRIAL PROTEIN; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RESPIRATORY CHAIN COMPLEX I; RESPIRATORY CHAIN COMPLEX IV; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ULTRASTRUCTURE; CITRIC ACID CYCLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FATTY ACID OXIDATION; GROWTH RETARDATION; HYPOALBUMINEMIA; MALNUTRITION; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PEROXISOME; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN RESTRICTION; PROTEOMICS; RAT; ANIMAL; CHILD; FATTY LIVER; HUMAN; LIVER; MITOCHONDRION; OXIDATION REDUCTION REACTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHILD; FATTY LIVER; HUMANS; LIVER; MALNUTRITION; MITOCHONDRIA; OXIDATION-REDUCTION; RATS;

EID: 85004125571     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2016.05.046     Document Type: Article

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