Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids

Autophagy

Volumn 10, Issue 3, 2014, Pages 431-441

  Sahani, Mayurbhai Himatbhai ^a,b   Itakura, Eisuke ^a,c   Mizushima, Noboru ^a,b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Amino acid; SQSTM1 p62; Transcription

Indexed keywords

AMINO ACID; CELL PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN P62; SEQUESTOSOME 1; UNCLASSIFIED DRUG; HEAT SHOCK PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN; SQSTM1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DEGRADATION; EMBRYO; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; KWASHIORKOR; LYSOSOME; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; UPREGULATION; ANIMAL; CELL LINE; METABOLISM; PHYSIOLOGY; STARVATION; TRANSCRIPTION INITIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACIDS; ANIMALS; AUTOPHAGY; CELL LINE; HEAT-SHOCK PROTEINS; HUMANS; LYSOSOMES; MICE; MICROTUBULE-ASSOCIATED PROTEINS; STARVATION; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84896970273     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.27344     Document Type: Article

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