메뉴 건너뛰기




Volumn 17, Issue 10, 2016, Pages 2632-2647

Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; LAMIN B; LAMIN B1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 85003009337     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.11.022     Document Type: Article
Times cited : (91)

References (50)
  • 2
    • 84908399662 scopus 로고    scopus 로고
    • DNA-damage response during mitosis induces whole-chromosome missegregation
    • Bakhoum, S.F., Kabeche, L., Murnane, J.P., Zaki, B.I., Compton, D.A., DNA-damage response during mitosis induces whole-chromosome missegregation. Cancer Discov. 4 (2014), 1281–1289.
    • (2014) Cancer Discov. , vol.4 , pp. 1281-1289
    • Bakhoum, S.F.1    Kabeche, L.2    Murnane, J.P.3    Zaki, B.I.4    Compton, D.A.5
  • 3
    • 84884365015 scopus 로고    scopus 로고
    • The causes and consequences of genetic heterogeneity in cancer evolution
    • Burrell, R.A., McGranahan, N., Bartek, J., Swanton, C., The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501 (2013), 338–345.
    • (2013) Nature , vol.501 , pp. 338-345
    • Burrell, R.A.1    McGranahan, N.2    Bartek, J.3    Swanton, C.4
  • 5
    • 84862777815 scopus 로고    scopus 로고
    • Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
    • Chen, G., Bradford, W.D., Seidel, C.W., Li, R., Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature 482 (2012), 246–250.
    • (2012) Nature , vol.482 , pp. 246-250
    • Chen, G.1    Bradford, W.D.2    Seidel, C.W.3    Li, R.4
  • 6
    • 33644681986 scopus 로고    scopus 로고
    • The advantages and disadvantages of being polyploid
    • Comai, L., The advantages and disadvantages of being polyploid. Nat. Rev. Genet. 6 (2005), 836–846.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 836-846
    • Comai, L.1
  • 9
    • 0034785348 scopus 로고    scopus 로고
    • TGF—beta signaling in tumor suppression and cancer progression
    • Derynck, R., Akhurst, R.J., Balmain, A., TGF—beta signaling in tumor suppression and cancer progression. Nat. Genet. 29 (2001), 117–129.
    • (2001) Nat. Genet. , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 11
    • 84948429460 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
    • Fischer, K.R., Durrans, A., Lee, S., Sheng, J., Li, F., Wong, S.T., Choi, H., El Rayes, T., Ryu, S., Troeger, J., et al. Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature 527 (2015), 472–476.
    • (2015) Nature , vol.527 , pp. 472-476
    • Fischer, K.R.1    Durrans, A.2    Lee, S.3    Sheng, J.4    Li, F.5    Wong, S.T.6    Choi, H.7    El Rayes, T.8    Ryu, S.9    Troeger, J.10
  • 13
    • 67649467032 scopus 로고    scopus 로고
    • A mechanism linking extra centrosomes to chromosomal instability
    • Ganem, N.J., Godinho, S.A., Pellman, D., A mechanism linking extra centrosomes to chromosomal instability. Nature 460 (2009), 278–282.
    • (2009) Nature , vol.460 , pp. 278-282
    • Ganem, N.J.1    Godinho, S.A.2    Pellman, D.3
  • 14
    • 0034716888 scopus 로고    scopus 로고
    • A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
    • Grosshans, J., Wieschaus, E., A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell 101 (2000), 523–531.
    • (2000) Cell , vol.101 , pp. 523-531
    • Grosshans, J.1    Wieschaus, E.2
  • 15
    • 84930719986 scopus 로고    scopus 로고
    • Lamins: Nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation
    • Gruenbaum, Y., Foisner, R., Lamins: Nuclear intermediate filament proteins with fundamental functions in nuclear mechanics and genome regulation. Annu. Rev. Biochem. 84 (2015), 131–164.
    • (2015) Annu. Rev. Biochem. , vol.84 , pp. 131-164
    • Gruenbaum, Y.1    Foisner, R.2
  • 16
    • 60749108426 scopus 로고    scopus 로고
    • Orchestrating nuclear envelope disassembly and reassembly during mitosis
    • Güttinger, S., Laurell, E., Kutay, U., Orchestrating nuclear envelope disassembly and reassembly during mitosis. Nat. Rev. Mol. Cell Biol. 10 (2009), 178–191.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 178-191
    • Güttinger, S.1    Laurell, E.2    Kutay, U.3
  • 17
    • 84879956366 scopus 로고    scopus 로고
    • Catastrophic nuclear envelope collapse in cancer cell micronuclei
    • Hatch, E.M., Fischer, A.H., Deerinck, T.J., Hetzer, M.W., Catastrophic nuclear envelope collapse in cancer cell micronuclei. Cell 154 (2013), 47–60.
    • (2013) Cell , vol.154 , pp. 47-60
    • Hatch, E.M.1    Fischer, A.H.2    Deerinck, T.J.3    Hetzer, M.W.4
  • 18
    • 84985919203 scopus 로고    scopus 로고
    • B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in Drosophila male meiosis
    • Hayashi, D., Tanabe, K., Katsube, H., Inoue, Y.H., B-type nuclear lamin and the nuclear pore complex Nup107-160 influences maintenance of the spindle envelope required for cytokinesis in Drosophila male meiosis. Biol. Open 5 (2016), 1011–1021.
    • (2016) Biol. Open , vol.5 , pp. 1011-1021
    • Hayashi, D.1    Tanabe, K.2    Katsube, H.3    Inoue, Y.H.4
  • 19
    • 80053364894 scopus 로고    scopus 로고
    • Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
    • Janssen, A., van der Burg, M., Szuhai, K., Kops, G.J., Medema, R.H., Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations. Science 333 (2011), 1895–1898.
    • (2011) Science , vol.333 , pp. 1895-1898
    • Janssen, A.1    van der Burg, M.2    Szuhai, K.3    Kops, G.J.4    Medema, R.H.5
  • 20
    • 10344255835 scopus 로고    scopus 로고
    • TGF—beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells
    • Kim, E.S., Kim, M.S., Moon, A., TGF—beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells. Int. J. Oncol. 25 (2004), 1375–1382.
    • (2004) Int. J. Oncol. , vol.25 , pp. 1375-1382
    • Kim, E.S.1    Kim, M.S.2    Moon, A.3
  • 21
    • 81255205399 scopus 로고    scopus 로고
    • Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
    • Labelle, M., Begum, S., Hynes, R.O., Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell 20 (2011), 576–590.
    • (2011) Cancer Cell , vol.20 , pp. 576-590
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 22
    • 84971222718 scopus 로고    scopus 로고
    • Mechanisms and Consequences of Cancer Genome Instability: Lessons from Genome Sequencing Studies
    • Lee, J.K., Choi, Y.L., Kwon, M., Park, P.J., Mechanisms and Consequences of Cancer Genome Instability: Lessons from Genome Sequencing Studies. Annu. Rev. Pathol. 11 (2016), 283–312.
    • (2016) Annu. Rev. Pathol. , vol.11 , pp. 283-312
    • Lee, J.K.1    Choi, Y.L.2    Kwon, M.3    Park, P.J.4
  • 23
    • 84948426563 scopus 로고    scopus 로고
    • Cell fate: Transition loses its invasive edge
    • Maheswaran, S., Haber, D.A., Cell fate: Transition loses its invasive edge. Nature 527 (2015), 452–453.
    • (2015) Nature , vol.527 , pp. 452-453
    • Maheswaran, S.1    Haber, D.A.2
  • 24
    • 77956924034 scopus 로고    scopus 로고
    • Inheriting nuclear organization: Can nuclear lamins impart spatial memory during post-mitotic nuclear assembly?
    • Martin, C., Chen, S., Jackson, D.A., Inheriting nuclear organization: Can nuclear lamins impart spatial memory during post-mitotic nuclear assembly?. Chromosome Res. 18 (2010), 525–541.
    • (2010) Chromosome Res. , vol.18 , pp. 525-541
    • Martin, C.1    Chen, S.2    Jackson, D.A.3
  • 25
    • 47549090432 scopus 로고    scopus 로고
    • TGF-beta in Cancer
    • Massagué, J., TGF-beta in Cancer. Cell 134 (2008), 215–230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massagué, J.1
  • 26
    • 0034716905 scopus 로고    scopus 로고
    • Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis
    • Mata, J., Curado, S., Ephrussi, A., Rørth, P., Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis. Cell 101 (2000), 511–522.
    • (2000) Cell , vol.101 , pp. 511-522
    • Mata, J.1    Curado, S.2    Ephrussi, A.3    Rørth, P.4
  • 27
    • 84904325891 scopus 로고    scopus 로고
    • MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes
    • McAlister, G.C., Nusinow, D.P., Jedrychowski, M.P., Wühr, M., Huttlin, E.L., Erickson, B.K., Rad, R., Haas, W., Gygi, S.P., MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Anal. Chem. 86 (2014), 7150–7158.
    • (2014) Anal. Chem. , vol.86 , pp. 7150-7158
    • McAlister, G.C.1    Nusinow, D.P.2    Jedrychowski, M.P.3    Wühr, M.4    Huttlin, E.L.5    Erickson, B.K.6    Rad, R.7    Haas, W.8    Gygi, S.P.9
  • 29
    • 74949093198 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer
    • Miyazono, K., Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. 85 (2009), 314–323.
    • (2009) Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. , vol.85 , pp. 314-323
    • Miyazono, K.1
  • 30
    • 1242307447 scopus 로고    scopus 로고
    • Morphogenesis during Xenopus gastrulation requires Wee1-mediated inhibition of cell proliferation
    • Murakami, M.S., Moody, S.A., Daar, I.O., Morrison, D.K., Morphogenesis during Xenopus gastrulation requires Wee1-mediated inhibition of cell proliferation. Development 131 (2004), 571–580.
    • (2004) Development , vol.131 , pp. 571-580
    • Murakami, M.S.1    Moody, S.A.2    Daar, I.O.3    Morrison, D.K.4
  • 34
    • 34250654965 scopus 로고    scopus 로고
    • The comet assay: A method to measure DNA damage in individual cells
    • Olive, P.L., Banáth, J.P., The comet assay: A method to measure DNA damage in individual cells. Nat. Protoc. 1 (2006), 23–29.
    • (2006) Nat. Protoc. , vol.1 , pp. 23-29
    • Olive, P.L.1    Banáth, J.P.2
  • 35
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo, A., Gupta, P.B., Sgroi, D.C., Arenzana-Seisdedos, F., Delaunay, T., Naeem, R., Carey, V.J., Richardson, A.L., Weinberg, R.A., Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121 (2005), 335–348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 36
    • 84901787644 scopus 로고    scopus 로고
    • Oncogenic roles of EMT-inducing transcription factors
    • Puisieux, A., Brabletz, T., Caramel, J., Oncogenic roles of EMT-inducing transcription factors. Nat. Cell Biol. 16 (2014), 488–494.
    • (2014) Nat. Cell Biol. , vol.16 , pp. 488-494
    • Puisieux, A.1    Brabletz, T.2    Caramel, J.3
  • 38
    • 0034213302 scopus 로고    scopus 로고
    • Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation
    • Seher, T.C., Leptin, M., Tribbles, a cell-cycle brake that coordinates proliferation and morphogenesis during Drosophila gastrulation. Curr. Biol. 10 (2000), 623–629.
    • (2000) Curr. Biol. , vol.10 , pp. 623-629
    • Seher, T.C.1    Leptin, M.2
  • 41
    • 84887456252 scopus 로고    scopus 로고
    • The epigenetics of epithelial-mesenchymal plasticity in cancer
    • Tam, W.L., Weinberg, R.A., The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat. Med. 19 (2013), 1438–1449.
    • (2013) Nat. Med. , vol.19 , pp. 1438-1449
    • Tam, W.L.1    Weinberg, R.A.2
  • 42
    • 84876451247 scopus 로고    scopus 로고
    • Tumor dissemination: An EMT affair
    • Thiery, J.P., Lim, C.T., Tumor dissemination: An EMT affair. Cancer Cell 23 (2013), 272–273.
    • (2013) Cancer Cell , vol.23 , pp. 272-273
    • Thiery, J.P.1    Lim, C.T.2
  • 43
    • 80155124832 scopus 로고    scopus 로고
    • MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
    • Ting, L., Rad, R., Gygi, S.P., Haas, W., MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics. Nat. Methods 8 (2011), 937–940.
    • (2011) Nat. Methods , vol.8 , pp. 937-940
    • Ting, L.1    Rad, R.2    Gygi, S.P.3    Haas, W.4
  • 45
    • 84860122715 scopus 로고    scopus 로고
    • Transient nuclear envelope rupturing during interphase in human cancer cells
    • Vargas, J.D., Hatch, E.M., Anderson, D.J., Hetzer, M.W., Transient nuclear envelope rupturing during interphase in human cancer cells. Nucleus 3 (2012), 88–100.
    • (2012) Nucleus , vol.3 , pp. 88-100
    • Vargas, J.D.1    Hatch, E.M.2    Anderson, D.J.3    Hetzer, M.W.4
  • 47
    • 84941243013 scopus 로고    scopus 로고
    • Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
    • Ye, X., Tam, W.L., Shibue, T., Kaygusuz, Y., Reinhardt, F., Ng Eaton, E., Weinberg, R.A., Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature 525 (2015), 256–260.
    • (2015) Nature , vol.525 , pp. 256-260
    • Ye, X.1    Tam, W.L.2    Shibue, T.3    Kaygusuz, Y.4    Reinhardt, F.5    Ng Eaton, E.6    Weinberg, R.A.7
  • 50
    • 84948407218 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
    • Zheng, X., Carstens, J.L., Kim, J., Scheible, M., Kaye, J., Sugimoto, H., Wu, C.C., LeBleu, V.S., Kalluri, R., Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature 527 (2015), 525–530.
    • (2015) Nature , vol.527 , pp. 525-530
    • Zheng, X.1    Carstens, J.L.2    Kim, J.3    Scheible, M.4    Kaye, J.5    Sugimoto, H.6    Wu, C.C.7    LeBleu, V.S.8    Kalluri, R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.